Co-localization of Protein Z, Protein Z-Dependent protease inhibitor and coagulation factor X in human colon cancer tissue: implications for coagulation regulation on tumor cells.

abstract：BACKGROUND:The methodology of thromboprophylaxis post minimally invasive esophagectomy (MIE) is unclear. Thus, we compared the efficacy and safety of fondaparinux and nadroparin on the prophylaxis of venous thromboembolism (VTE) after MIE. MATERIALS AND METHODS:We conducted a randomized, double-blind, treatment-contro...

journal_title：Thrombosis research

authors： Song J,Xuan L,Wu W,Shen Y,Tan L,Zhong M

更新日期：2018-06-01 00:00:00

abstract：BACKGROUND:Upon platelet stimulation with agonists, reactive oxygen species (ROS) generation enhances platelet activation and granule release. Whether ROS generation during platelet storage could be directly correlated with the expression of proinflammatory molecules and granule release has been investigated in this st...

journal_title：Thrombosis research

authors： Ghasemzadeh M,Hosseini E

更新日期：2017-08-01 00:00:00

abstract：:Eicosapentaenoic acid (EPA) has been reported to have a potent anti-aggregatory activity and to be efficiently metabolized by 12-lipoxygenase, not by cyclooxygenase in platelets. In vitro effect of 12-lipoxygenase metabolites of EPA on platelet function was studied and compared with those of arachidonic acid (AA). The...

journal_title：Thrombosis research

authors： Takenaga M,Hirai A,Terano T,Tamura Y,Kitagawa H,Yoshida S

更新日期：1986-02-01 00:00:00

abstract：:Cross reactive antigens to factor VIII have been measured in a range of vertebrate phyla. VIII coagulant antigen (VIII:CAg) measured using a human antibody was in general, much lower than reported values of VIII coagulant activity (VIII:C) except in simians and the guinea pig. The dose response curve for the assay was...

journal_title：Thrombosis research

authors： Rotblat F,Hawkey C,O'Brien DP,Tuddenham EG

更新日期：1982-03-01 00:00:00

abstract：:The fibrin sleeve of venous catheters (VC) and parietal thrombi represent frequent and dangerous side-effects of central venous catheterization (CVC), due to the risk of embolism. Reduced levels of coagulation clotting factors inhibitors (such as Antithrombin III) are known to be associated with increased thrombogenic...

journal_title：Thrombosis research

authors： De Cicco M,Matovic M,Balestreri L,De Angelis V,Fracasso A,Morassut S,Coran F,Babare R,Buonadonna A,Testa V

更新日期：1995-04-15 00:00:00

abstract：INTRODUCTION:Post-thrombotic syndrome (PTS) is a chronic sequel of deep vein thrombosis (DVT). The clot structure and fibrinolytic potential in PTS is currently unknown. OBJECTIVE:To assess the fibrinolytic potential and clot structure in patients with PTS. MATERIALS AND METHODS:Patients with a history of DVT were in...

journal_title：Thrombosis research

authors： Bouman AC,McPherson H,Cheung YW,Ten Wolde M,Ten Cate H,Ariëns RAS,Ten Cate-Hoek AJ

更新日期：2016-01-01 00:00:00

abstract：:Activation of human platelets by PAF was augmented by C-reactive protein, an acute phase plasma protein. The concentration of PAF required for irreversible activation (secondary aggregation of platelet and release of serotonin) was decreased to 1/10 in the presence of C-reactive protein (CRP). The presence of CRP stim...

journal_title：Thrombosis research

authors： Kohayakawa M,Inoue K

更新日期：1986-03-01 00:00:00

abstract：INTRODUCTION:Viscoelastometry enables rapid evaluation of coagulopathy in settings such as cardiac surgery but may be influenced by red cell concentration. METHODS:In order to study the effects of supra-physiological red cell concentrations on viscoelastometry, we compared ROTEM® viscoelastometry and plasma coagulatio...

journal_title：Thrombosis research

authors： Westbury SK,Lee K,Reilly-Stitt C,Tulloh R,Mumford AD

更新日期：2013-08-01 00:00:00

abstract：:Bovine hide collagen dispersions were swollen in the pH range 1.6-7.0, treated with glutaraldehyde, and dialyzed to neutral pH. The intensity with which these collagens reacted with human platelets in plasma was studied by aggregometry and scanning electron microscopy. Collagen swollen at a pH below 4.25 +/- 0.30 and ...

journal_title：Thrombosis research

authors： Sylvester MF,Yannas IV,Salzman EW,Forbes MJ

更新日期：1989-07-01 00:00:00

abstract：INTRODUCTION:Retinal vein occlusion is a major cause of ocular morbidity. The precise mechanism leading to thrombosis in retinal vein occlusion has not yet been clearly elucidated. Several risk factors have been identified, including hypertension diabetes, history of cardiovascular disease, hypercholesterolemia, hyperh...

journal_title：Thrombosis research

authors： Leoncini G,Signorello MG,Segantin A,Giacobbe E,Armani U,Piana A,Camicione P

更新日期：2009-12-01 00:00:00

abstract：INTRODUCTION:Venous thromboembolism is a common cause of morbidity and mortality. Although cirrhosis has classically been considered as an acquired bleeding diathesis, there is increasing evidence that rejects the traditional belief that these patients are naturally protected against venous thromboembolism. However, an...

journal_title：Thrombosis research

authors： Gómez Cuervo C,Bisbal Pardo O,Pérez-Jacoiste Asín MA

更新日期：2013-10-01 00:00:00

abstract：BACKGROUND:Brain tumor patients have an increased risk of venous thromboembolism (VTE). An important role in cancer-related VTE has been suggested for tissue factor (TF), the main initiator of the coagulation cascade. We conducted a prospective cohort study to determine whether expression levels of TF in brain tumors a...

journal_title：Thrombosis research

authors： Thaler J,Preusser M,Ay C,Kaider A,Marosi C,Zielinski C,Pabinger I,Hainfellner JA

更新日期：2013-02-01 00:00:00

abstract：:Triflavin, an Arg-Gly-Asp (RGD)-containing disintegrin purified from venom peptide inhibited platelet aggregation by interfering with the interaction of fibrinogen with alpha(IIb)beta(3) integrin. Using an immunostaining technique and electron microscopy, we investigated and compared the distribution of triflavin bind...

journal_title：Thrombosis research

authors： Chuang WJ,Wu CH,Huang HN,Chen SH,Hsiao G,Lin CH,Sheu JR

更新日期：2003-01-01 00:00:00

abstract：:Washed human platelets were incubated with commercial factor VIII concentrate, or with purified factor VIII coagulant moiety. Platelets were then washed again and lysed by sonication. VIII:Ag and vWf:Ag were measured in the platelet lysate prior to and after incubation of the lysate with phospholipase C (PL-C). Platel...

journal_title：Thrombosis research

authors： Muntean W,Leschnik B,Haas J

更新日期：1987-02-15 00:00:00

abstract：:Most proteolytic enzymes that cleave glycoprotein lb (GPlb) also cleave other glycoproteins or receptors on the surface of platelets. We have used an O-sialoglycoprotein endoprotease from Pasteurella haemolytica that selectively cleaves the heavily O-glycosylated GPlb, but does not cleave N-linked glycoproteins or ung...

journal_title：Thrombosis research

authors： Kinlough-Rathbone RL,Perry DW,Rand ML,Packham MA

更新日期：2000-07-15 00:00:00

abstract：:In this paper, we demonstrated that the procoagulant action of Lonomia achelous (Cramer) is due in part to a component that activates prothrombin. The activation by crude venom and Fractions obtained by gel filtration on Sephadex G-75 is not dependent of phospholipid, Ca++ or Factor V. The activation of prothrombin by...

journal_title：Thrombosis research

authors： Guerrero B,Arocha-Piñango CL

更新日期：1992-05-01 00:00:00

abstract：:Platelet concentrates (PC) were prepared by platelet apheresis to obtain a low (< 0.1 x 10(9)/l, PC A) and high (2-9 x 10(9)/l, PC B) concentration of white cells from the same donor. The mean platelet count (+/- SD) of the PC were 1000 +/- 50 x 10(9)/l. During storage 71-96% of the white cells were mononuclear. A por...

journal_title：Thrombosis research

authors： Wallvik J,Suontaka AM

更新日期：1993-05-01 00:00:00

abstract：INTRODUCTION:Pathogenesis of idiopathic pulmonary arterial hypertension (iPAH) includes endothelial dysfunction and in situ thrombosis. A hypercoagulable state has also been postulated but never demonstrated. Our objective was to determine whether patients with iPAH had a hypercoagulable state using calibrated automate...

journal_title：Thrombosis research

authors： Tournier A,Wahl D,Chaouat A,Max JP,Regnault V,Lecompte T,Chabot F

更新日期：2010-12-01 00:00:00

abstract：INTRODUCTION:Pelvic deep vein thrombosis (DVT) is difficult to diagnose during pregnancy. In a two-center trial, we evaluated the agreement between ultrasonography and magnetic resonance imaging (MRI) in diagnosing the extent of DVT into the pelvic veins during pregnancy. MATERIALS AND METHODS:Pregnant women with prox...

journal_title：Thrombosis research

authors： Torkzad MR,Bremme K,Hellgren M,Eriksson MJ,Hagman A,Jörgensen T,Lund K,Sandgren G,Blomqvist L,Kälebo P

更新日期：2010-08-01 00:00:00

abstract：:We investigated the age-related changes in blood coagulation, fibrinolysis, and platelet aggregation in male WBN/Kob rats, animals that exhibit spontaneously diabetes mellitus at more than 6 months of age. The rats aged 6 months or more showed significant hyperglycemia, hypoinsulinemia, and hyperlipidemia. As changes ...

journal_title：Thrombosis research

authors： Nobukata H,Ishikawa T,Obata M,Shibutani Y

更新日期：2000-06-15 00:00:00

abstract：BACKGROUND/AIM:It is believed that the amniotic fluid-derived TF, in the case of amniotic fluid embolism (AFE), contributes to acute disseminated intravascular coagulation (DIC) and obstetric shock in the mother. However, the role of amniotic fluid-derived contact phase coagulation factors that irrupt into the bloodstr...

journal_title：Thrombosis research

authors： Uszyński W,Żekanowska E,Uszyński M,Kieszkowski P

更新日期：2015-04-01 00:00:00

abstract：:A simple and reproducible method to induce an occlusive thrombus in rabbit carotid artery is reported. Rabbits were anesthetized and prepared to record arterial pressure, heart rate, and carotid blood flow. A critical stenosis of a damaged carotid artery was obtained using an external plastic cylinder. Complete occlus...

journal_title：Thrombosis research

authors： Bevilacqua C,Finesso M,Prosdocimi M

更新日期：1991-05-15 00:00:00

abstract：:Carotid artery dissections are the second leading cause of stroke in young adults. The hemostatic response to a dissection involves exposure of the subendothelium to the intravascular environment. Platelet activation/aggregation superimposed by secondary coagulation cascade activity attempts to heal the injury. Failur...

journal_title：Thrombosis research

authors： Stevic I,Chan HH,Chan AK

更新日期：2011-10-01 00:00:00

abstract：:Evidence is presented for in vitro high affinity binding of serotonin (5-HT) by beta-thromboglobulin (beta TG) and platelet factor 4 (PF4) from human blood. Results include: 1) identification by radioimmunoassay of PF4 in specifically bound material obtained by 5-HT affinity chromatography of human platelet extracts; ...

journal_title：Thrombosis research

authors： Heemstra VL

更新日期：1983-02-01 00:00:00

abstract：INTRODUCTION:Bivalirudin is an alternative to heparin anticoagulation in infants and children in the setting of extracorporeal life support (ECLS). While activated partial thromboplastin time (aPTT) is widely accepted as the standard test to monitor bivalirudin therapy, the usefulness of thromboelastometry (ROTEM) to m...

journal_title：Thrombosis research

authors： Teruya J,Hensch L,Bruzdoski K,Adachi I,Hui SR,Kostousov V

更新日期：2020-02-01 00:00:00

abstract：:Acute coronary syndromes (ACS) represent the main clinical manifestation of atherosclerotic progression in the coronary district. Thrombosis plays a critical role in the patho-anatomical of ACS, as disruption of an atherosclerotic plaque exposes flowing blood to subendothelial collagen, tissue factor, and other procoa...

journal_title：Thrombosis research

authors： Abbate R,Cioni G,Ricci I,Miranda M,Gori AM

更新日期：2012-03-01 00:00:00

abstract：INTRODUCTION:Von Willebrand Disease (VWD) is the most common inherited bleeding disorder. Measurement of von Willebrand factor (VWF) activity in plasma is often based on platelet agglutination stimulated by the ristocetin cofactor activity. Novel assays, based on latex beads with recombinant glycoprotein Ib instead of ...

journal_title：Thrombosis research

authors： Timm A,Hillarp A,Philips M,Goetze JP

更新日期：2015-04-01 00:00:00

abstract：:We have investigated the role of platelet activating factor (PAF) in the pathogenesis of a murine model of traumatic shock using WEB 2086, a specific antagonist of PAF. WEB 2086 (0.5 mg/kg) significantly reversed the decrease in mean arterial blood pressure (MABP) induced by PAF (0.3 micrograms/kg) in anesthetized rat...

journal_title：Thrombosis research

authors： Stahl GL,Bitterman H,Lefer AM

更新日期：1989-02-01 00:00:00

abstract：BACKGROUND:Pulmonary embolism (PE) is diagnosed with imaging techniques such as ventilation/perfusion (V/P) lung scintigraphy or multidetector computed tomography of the pulmonary arteries (MDCT). Lung scintigraphy can be performed with planar (V/P PLANAR) and tomographic (V/P SPECT) techniques. V/P SPECT has higher se...

journal_title：Thrombosis research

authors： Alhadad A,Miniati M,Alhadad H,Gottsäter A,Bajc M

更新日期：2012-12-01 00:00:00

abstract：INTRODUCTION:Growth differentiation factor-15 (GDF-15) has been identified as a predictor in cardiovascular diseases and acute pulmonary embolism. However, the association of GDF-15 and deep venous thrombosis (DVT) remains unclear. This study aimed to investigate levels of GDF-15 in patients with DVT, and determine its...

journal_title：Thrombosis research

authors： Liang W,Wei F,Yang C,Xie F,Shuai XX,Wang M,Yu M

更新日期：2020-03-01 00:00:00