Acute carotid artery occlusive thrombosis and its pharmacological prevention in the rabbit.

abstract：BACKGROUND:Predictors of venous thromboembolism (VTE) after trauma are uncertain. OBJECTIVE:To identify independent predictors of VTE after acute trauma. METHODS:Using Rochester Epidemiology Project (REP) resources, we identified all Olmsted County, MN residents with objectively-diagnosed incident VTE within 92days a...

journal_title：Thrombosis research

authors： Park MS,Perkins SE,Spears GM,Ashrani AA,Leibson CL,Boos CM,Harmsen WS,Jenkins DH,Bailey KR,Ballman KV,Heit JA

更新日期：2016-08-01 00:00:00

abstract：:ACS patients undergoing percutaneous coronary intervention (PCI) when treated with bivalirudin and clopidogrel had increased frequency of early stent thrombosis. 24 patients referred for intervention with planned bivalirudin therapy, not previously treated with a P2Y12 inhibitor and not receiving heparins or αIIbβ3 in...

journal_title：Thrombosis research

authors： Kimmelstiel C,Stevenson R,Nguyen N,Van Doren L,Zhang P,Perkins J,Kapur NK,Weintraub A,Castaneda V,Kuliopulos A,Covic L

更新日期：2019-05-01 00:00:00

abstract：BACKGROUND:There is a perception in the orthopaedic and thromboembolism community that the incidence of deep vein thrombosis (DVT) has decreased in patients undergoing total knee arthroplasty (TKA) or total hip arthroplasty (THA). OBJECTIVES:To assess the incidence of DVT with warfarin thromboprophylaxis over time in ...

journal_title：Thrombosis research

authors： Xing KH,Morrison G,Lim W,Douketis J,Odueyungbo A,Crowther M

更新日期：2008-01-01 00:00:00

abstract：INTRODUCTION:Remote ischaemic conditioning (RIC) has been shown to prevent platelet activation during ablation for atrial fibrillation. RIC has also been associated with more postoperative transfusion in the off-pump coronary artery bypass graft surgery (OPCAB) patients. We evaluated the effects of RIC on coagulation f...

journal_title：Thrombosis research

authors： Kim TK,Nam K,Cho YJ,Choi S,Row HS,Jeon Y

更新日期：2020-03-01 00:00:00

abstract：INTRODUCTION:The prevalence and etiology of occult bleeding among patients on warfarin who are screened systematically for new anemia is largely unknown. We aimed to estimate the usefulness of following hemoglobin and mean red cell volume (MCV) with INR in order to screen for developing anemia as an indicator of occult...

journal_title：Thrombosis research

authors： Johannsdottir GA,Onundarson PT,Gudmundsdottir BR,Bjornsson ES

更新日期：2012-09-01 00:00:00

abstract：:The soluble fibrin monomer complexes (SFMC) in 154 obstetric patients with possible disseminated intravascular coagulation (DIC) were evaluated in SDS polyacrylamide gel electrophoresis (PAGE) after precipitation with B-alanine. Other coagulation tests were performed on these patients. The patients were classified int...

journal_title：Thrombosis research

authors： Aznar J,Gilabert J,Estelles A,Fernandez MA,Villa P,Aznar JA

更新日期：1982-09-15 00:00:00

abstract：:A frequent complication of venous access devices (VADs) is axillary-subclavian venous thrombosis. To study this problem we have compared blood drawn through VADs with peripheral blood samples in a group of oncology patients with venographically demonstrated venous damage (N = 14) and a group with normal venograms (N =...

journal_title：Thrombosis research

authors： Horne MK 3rd,Merryman PK,Mayo DJ,Gralnick HR,Chang RC,Alexander HR

更新日期：1995-08-15 00:00:00

abstract：:Thrombocytopenia is a common finding in cancer patients and can have different and/or multifactorial pathogenesis. While in solid tumors it occurs often as a consequence of chemotherapy treatment, it is frequently observed at diagnosis in patients with hematological malignancies being aggravated to a potentially life-...

journal_title：Thrombosis research

authors： Castaman G,Pieri L

更新日期：2018-04-01 00:00:00

abstract：:Lysophosphatidic acid (LPA) is a lipid mediator generated by activated platelets and having various effects on numerous cell types. We investigated some effects of 1-oleyl LPA on vascular smooth muscle cells cultured from adult human normal arteries. At micromolar concentrations, LPA induced a mitogenic effect ([3H]-t...

journal_title：Thrombosis research

authors： Gennero I,Xuereb JM,Simon MF,Girolami JP,Bascands JL,Chap H,Boneu B,Sié P

更新日期：1999-06-01 00:00:00

abstract：:The hemolytic uremic syndrome involves the presence of Shiga toxin producing strains of Escherichia coli and is associated with thrombocytopenia, platelet activation, and microthrombi formation. We have, therefore, investigated the ability of Shiga toxin isotypes 1 and 2 to cause or enhance platelet aggregation under ...

journal_title：Thrombosis research

authors： Viisoreanu D,Polanowska-Grabowska R,Suttitanamongkol S,Obrig TG,Gear AR

更新日期：2000-06-01 00:00:00

abstract：OBJECTIVES:Dabigatran etexilate is widely used for stroke prevention in the patients with atrial fibrillation. The anticoagulation activity of dabigatran is not necessary monitored in routine clinical practice. We aimed to study the effect of dabigatran on thrombin generation (TG) and coagulation assays in rabbit and h...

journal_title：Thrombosis research

authors： Zhang C,Zhang P,Li H,Han L,Zhang L,Zhang L,Yang X

更新日期：2018-05-01 00:00:00

abstract：:Effects of mechanical trauma of platelets and red blood cells on dynamic viscoelasticity of blood during clotting were examined. Two different methods were attempted to give the mechanical damage to blood cells. In one method, a flow apparatus consisting of a thin teflon tube and two sample reservoirs connecting to bo...

journal_title：Thrombosis research

authors： Kaibara M,Ukiya Y,Sekiguchi M

更新日期：1986-08-15 00:00:00

abstract：BACKGROUND:The usefulness of coagulation tests performed before epidural analgesia for surgery or to alleviate labour pain is controversial. The aims of this study were: (1) to evaluate the prevalence of abnormal tests in a large cohort of healthy pregnant women and their association with epidural hematoma; (2) to asse...

journal_title：Thrombosis research

authors： Franchi F,Ibrahim B,Rossi F,Maspero ML,Morabito O,Asti D,Bucciarelli P,Biguzzi E

更新日期：2011-07-01 00:00:00

abstract：:The multiligand receptor, low density lipoprotein receptor-related protein (LRP), is implicated in processes such as atherosclerosis and fibrinolysis through its mediation of the catabolism of lipoproteins, proteases, and protease inhibitor complexes. The hepatoma cell line Hep G2 expresses LRP and has been used widel...

journal_title：Thrombosis research

authors： Grimsley PG,Quinn KA,Chesterman CN,Owensby DA

更新日期：1997-12-15 00:00:00

abstract：:We characterized the antithrombotic, haemorrhagic, and ex vivo anticoagulant effects of a recently identified depolymerized holothurian glycosaminoglycan (DHG), and compared these effects with those of unfractionated heparin (UFH), low molecular weight heparin (LMWH), and dermatan sulfate (DS). In thrombin-induced ven...

journal_title：Thrombosis research

authors： Kitazato K,Kitazato KT,Nagase H,Minamiguchi K

更新日期：1996-10-15 00:00:00

abstract：:Ethamsylate possesses antihemorrhagic properties, but whether or not it directly activates blood platelets is unclear. Here we investigated the platelet activation potential of ethamsylate, by measuring membrane P-selectin expression with flow cytometry in human whole blood and also by immunofluorescence imaging of is...

journal_title：Thrombosis research

authors： Alvarez-Guerra M,Hernandez MR,Escolar G,Chiavaroli C,Garay RP,Hannaert P

更新日期：2002-09-15 00:00:00

abstract：:Blackfoot disease is a unique endemic and chronic progressive arteriosclerotic vascular disease in southwest area of Taiwan. In this study, we determined the plasma levels of tissue plasminogen activator (tPA), plasminogen activator inhibitor (PAI), urokinase plasminogen activator (uPA), and von Willebrand factor (vWF...

journal_title：Thrombosis research

authors： Wu HL,Yang WH,Wang MY,Shi GY

更新日期：1993-11-01 00:00:00

abstract：BACKGROUND/AIMS:The plasminogen activator (PA)-plasmin system is primarily involved in fibrinolysis, but is also in the patho/physiological events in which breakdown of extracellular matrices is evoked topically. In this present study, we examined the expression of fibrinolytic factors, tissue-type PA (t-PA) and Type 1...

journal_title：Thrombosis research

authors： Noguchi T,Matsuyama S,Akao M,Hagiwara H,Uno S,Seki T,Ariga T

更新日期：2001-11-15 00:00:00

abstract：UNLABELLED:We undertook a survey of French university hospital hematological laboratories to ascertain the clinical characteristics of patients with suspected HIT, the laboratory tests performed, and the therapeutic strategy adopted in current practice. METHODS:A standardized medical records database for patients with...

journal_title：Thrombosis research

authors： Bidet A,Tardy Poncet B,Desprez D,de Maistre E,Presles E,Lecompte T,Lavenu-Bombled C,Huisse MG,Wolf M,Morange P,Racadot E,Mouton C,Grunebaum L,Pouplard C,Tardy B,GEHT-HIT study group.

更新日期：2010-06-01 00:00:00

abstract：:The concentrations of tissue plasminogen activator (t-PA) and urokinase (UK) were measured in the plasma of patients with benign or malignant ovarian and uterine tumors. Plasma levels of t-PA were higher in patients with malignant ovarian and uterine tumors than in patients with benign tumors. Plasma UK levels were, h...

journal_title：Thrombosis research

authors： Saito K,Nagashima M,Iwata M,Hamada H,Sumiyoshi K,Takada Y,Takada A

更新日期：1990-05-15 00:00:00

abstract：:This prospective randomized study investigated the influence of normotensive and hypotensive general anesthesia on platelet aggregability, intraoperative blood loss and parameters of plasmatic coagulation during extensive orthognathic surgery. A total of 30 patients were randomly allocated for either normotensive anes...

journal_title：Thrombosis research

authors： Felfernig-Boehm D,Salat A,Kinstner C,Fleck T,Felfernig M,Kimberger O,Andel H,Mueller MR

更新日期：2001-08-01 00:00:00

abstract：INTRODUCTION:Medically ill, hospitalized patients are at increased risk for venous thromboembolism (VTE) after discharge. This study aimed to examine thromboprophylaxis patterns, risk factors, and post-discharge outcomes. METHODS:This was a retrospective claims analysis involving administrative claims data and in-pati...

journal_title：Thrombosis research

authors： Mahan CE,Fisher MD,Mills RM,Fields LE,Stephenson JJ,Fu AC,Spyropoulos AC

更新日期：2013-11-01 00:00:00

abstract：INTRODUCTION:Pulmonary embolism (PE) is a common cause of morbidity and mortality. In this study, we investigated patterns of morbidity and mortality from PE in Australia. MATERIALS & METHODS:Australian government databases were used to extract data on age and sex specific rates of mortality between 1997 and 2007, and...

journal_title：Thrombosis research

authors： Shiraev TP,Omari A,Rushworth RL

更新日期：2013-07-01 00:00:00

abstract：:Megakaryocyte colony formation was increased in 13 patients with ITP. Out of splenectomized ITP patients Colony Forming Unit-Megakaryocyte (CFU-Mk) number normalized in four but was lower than normal in the remaining two. The proportion of immature megakaryocytes was higher in ITP than in normals or in ITP patients af...

journal_title：Thrombosis research

authors： Podolak-Dawidziak M

更新日期：1991-04-01 00:00:00

abstract：INTRODUCTION:Changes in platelet count and function contribute to thrombo-hemorrhagic episodes in chronic myeloproliferative syndromes (MPS). We used flow cytometry to study platelet-leukocyte conjugates and markers of platelet activation in patients with MPS. METHODS:Whole blood from patients with chronic myelogenous...

journal_title：Thrombosis research

authors： Villmow T,Kemkes-Matthes B,Matzdorff AC

更新日期：2002-11-01 00:00:00

abstract：INTRODUCTION:Vitamin K antagonists are often used for anticoagulant treatment in hip fracture patients. The optimal handling with such anticoagulants is unclear. We aimed to determine when anticoagulation reversal occurred after vitamin K administration and how often prothrombin complex concentrates (PCCs) were adminis...

journal_title：Thrombosis research

authors： Buecking B,Eschbach D,Bliemel C,Oberkircher L,Struewer J,Ruchholtz S,Sachs UJ

更新日期：2014-01-01 00:00:00

abstract：:Chloroquine inhibited aggregation of rat blood platelets in a dose-dependent way. The inhibitory effect decreased, depending on the aggregation stimulus used, in the rank order of potency: ADP > thrombin > A23187. Effect of 1 millimolar chloroquine on A23187-stimulated aggregation was significantly decreased or comple...

journal_title：Thrombosis research

authors： Jancinová V,Nosál R,Petríková M

更新日期：1994-06-01 00:00:00

abstract：:The purpose of this study was to determine whether plasma von Willebrand factor concentrations are correlated with the degree of intestinal ischaemia-reperfusion injury. Forty-six anaesthetised adult Wistar rats were divided into five groups. The sham-operated group (S, n=10) had laparotomy and isolation of the superi...

journal_title：Thrombosis research

authors： Abu-Zidan FM,Farrant G,Zwi LJ,Simovic MO,Day T,Bonham MJ,Windsor JA

更新日期：1999-06-15 00:00:00

abstract：BACKGROUND:Advances in medical and surgical therapy in children have resulted in increased survival in children with primary illnesses. However, thrombosis is a serious complication of this success and results in mortality and morbidity. Prevention or treatment of thrombosis using warfarin is challenging in children du...

journal_title：Thrombosis research

authors： Bauman ME,Black K,Kuhle S,Wang L,Legge L,Callen-Wicks D,Mitchell L,Bajzar L,Massicotte MP,Western Canadian Children's Heart Network WCCHN.

更新日期：2009-03-01 00:00:00

abstract：:Aim of this study was to evaluate rapid D-Dimer tests for their utility in diagnosis of acute pulmonary embolism (PE). Tests were performed in 183 consecutive pats referred for lung scanning because of clinically suspected PE. According to lung scans and the clinical course of disease 19 pats were classified to have P...

journal_title：Thrombosis research

authors： Veitl M,Hamwi A,Kurtaran A,Virgolini I,Vukovich T

更新日期：1996-06-01 00:00:00