Prognostic Value of Subcarinal Lymph Nodes in Minimally Invasive Esophagectomy for Cancer.

abstract：BACKGROUND:Matrix metalloproteinase 9 (MMP-9) plays an important role in cancer invasion and metastasis. The relationship between serum MMP-9 levels and clinicopathological factors in gastric cancer patients is not clear. MATERIALS AND METHODS:Preoperative serum was obtained from 170 patients who had undergone gastrec...

journal_title：Anticancer research

authors： Shen KH,Chi CW,Lo SS,Kao HL,Lui WY,Wu CW

更新日期：2000-03-01 00:00:00

abstract：BACKGROUND/AIM:Oral cancer represents approximately 2.5% of all cancers in the United States, with five- and 10-year survival rates of 62% and 51%. In the present study, lyophilized strawberries (LS) were evaluated for their potential to inhibit tumorigenesis in the hamster cheek pouch (HCP) model of oral cancer and fo...

journal_title：Anticancer research

authors： Casto BC,Knobloch TJ,Galioto RL,Yu Z,Accurso BT,Warner BM

更新日期：2013-11-01 00:00:00

abstract：BACKGROUND:Trastuzumab has no major side-effects except the potential for cardiac toxicity. The main objective of this study was to evaluate the association between trastuzumab-associated cardiac toxicity and two potential risk factors: alcohol intake and HER2 polymorphisms. PATIENTS AND METHODS:In a retrospective coh...

journal_title：Anticancer research

authors： Lemieux J,Diorio C,Côté MA,Provencher L,Barabé F,Jacob S,St-Pierre C,Demers E,Tremblay-Lemay R,Nadeau-Larochelle C,Michaud A,Laflamme C

更新日期：2013-06-01 00:00:00

abstract：:Concentrations of soluble CD44 standard (sCD44std) and CD44 variant 6 (sCD44v6) isoforms were determined in the sera of 59 patients with distant metastasis from breast cancer receiving second line hormone- or chemotherapy, in comparison to 46 breast cancer patients without detectable recurrent disease and 21 healthy b...

journal_title：Anticancer research

authors： Kopp R,Classen S,Wolf H,Gholam P,Possinger K,Wilmanns W

更新日期：2001-07-01 00:00:00

abstract：BACKGROUND/AIM:Glioblastoma multiforme (GBM) is a malignant primary brain tumor with high rates of recurrence. This study aimed to investigate the effect of repurposed drug combinations on GBM. MATERIALS AND METHODS:Viability of U87 MG and 11ST patient-derived GMB cell lines, after valproic acid, tranylcypromine or ri...

journal_title：Anticancer research

authors： Sachkova A,Sperling S,Mielke D,Schatlo B,Rohde V,Ninkovic M

更新日期：2019-01-01 00:00:00

abstract：:This study investigated whether neuraminidase (Neu) affects LFA-1 mRNA expression in spleen cells and whether somatostatin (SOM) and substance P (SP) treatment induce changes in the Neu mRNA expression level in spleen cells. Neu treatments down-regulated the LFA-1 mRNA levels after culturing for 2 h. SOM increased the...

journal_title：Anticancer research

authors： Yoon WK,Kim HJ,Son HY,Jeong KS,Park SJ,Kim TH,Kim SH,Kim SR,Ryu SY

更新日期：2004-07-01 00:00:00

abstract：:To evaluate further the chemopreventive role of motherwort (Leonurus sibiricus L; MW) in lesions of the mammary gland and uterus of GR/A mice, the effects on these lesions of the adsorbed (MW1) and unadsorbed (MW2) fractions of MW separated by ion-exchange resins were studied. The incidence of palpable mammary tumours...

journal_title：Anticancer research

authors： Nagasawa H,Inatomi H,Suzuki M,Mori T

更新日期：1992-01-01 00:00:00

abstract：BACKGROUND:As cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) are being increasingly adopted as the standard treatment for peritoneal surface malignancies, familiarity with this procedure's adverse events is also growing. Herein, we describe an unreported adverse event of exocrine panc...

journal_title：Anticancer research

authors： Naffouje SA,Salti GI

更新日期：2018-04-01 00:00:00

abstract：BACKGROUND/AIM:The expression of sphingosine kinase-1 (SphK1) has been reported in several cancers. However, the exact roles of SphK1 in cancer progression still remain unknown. The aim of the present study was to investigate SphK1 expression in oral squamous cell carcinoma (OSCC) and clarify the involvement of SphK1 i...

journal_title：Anticancer research

authors： Kato K,Shimasaki M,Kato T,Segami N,Ueda Y

更新日期：2018-03-01 00:00:00

abstract：BACKGROUND:CD44 is a transmembrane glycoprotein and is associated with cell-matrix and cell-cell interactions. CD44 expression was shown to be relevant to tumour progression in various types of human cancer. The objective of this study was to investigate the relationship between the expression levels of the standard fo...

journal_title：Anticancer research

authors： Al-Maghrabi J,Gomaa W,Buhmeida A,Al-Qahtani M,Al-Ahwal M

更新日期：2012-08-01 00:00:00

abstract：BACKGROUND/AIM:In addition to its cytocidal effects as a microtubule dynamics inhibitor, eribulin mesylate (eribulin) regulates the tumour microenvironment. We examined the clinical significance of tumour infiltrating lymphocytes (TILs) and transforming growth factor-β (TGF-β), which are local markers of host immunity,...

journal_title：Anticancer research

authors： Kashiwagi S,Asano Y,Goto W,Takada K,Morisaki T,Kouhashi R,Yabumoto A,Tanaka S,Takashima T,Ohsawa M,Hirakawa K,Ohira M

更新日期：2020-06-01 00:00:00

abstract：BACKGROUND/AIM:Occult cancers' reported rates vary from 2-12% and serous tubal intraepithelial carcinomas (STICs) have been identified in 3-12% of the prophylactically removed tubes of women carrying a BRCA mutation. The aim of this study was to evaluate the incidence of tubal minor epithelial atypia (STIL), STIC, and ...

journal_title：Anticancer research

authors： Ricciardi E,Tomao F,Aletti G,Bazzurini L,Bocciolone L,Boveri S,Landoni F,Lapresa MT,Maruccio M,Parma G,Peccatori F,Petrella MC,Zanagnolo V,Colombo N,Maggioni A

更新日期：2017-09-01 00:00:00

abstract：BACKGROUND:The aim of this retrospective study was to evaluate the clinical relevance of serum p53 antibody (S-p53Ab) as a biomarker and to investigate whether its diagnostic value could be improved when combined with other biomarkers of gastric cancer (GC). PATIENTS AND METHODS:Serum samples were obtained preoperativ...

journal_title：Anticancer research

authors： Kunizaki M,Fukuda A,Wakata K,Tominaga T,Nonaka T,Miyazaki T,Matsumoto K,Sumida Y,Hidaka S,Yasutake T,Sawai T,Hamamoto R,Nanashima A,Nagayasu T

更新日期：2017-04-01 00:00:00

abstract：:The limited restriction of eucaryotic chromosomes would facilitate our understanding of the aberrant genomes of genetic diseases and cancer. We have described methods for methylating eucaryotic chromosomes embedded in agarose plugs. We now describe how Cla I methylase can be utilized in a methylation-dependent restric...

journal_title：Anticancer research

authors： Wilson WW,Mebane EW,Hoffman RM

更新日期：1993-01-01 00:00:00

abstract：BACKGROUND:Pleomorphic rhabdomyosarcomas of the uterus, mainly occurring in postmenopausal women with leading symptoms of vaginal bleeding and abdominal pain, are very rare malignant tumors of the female genital tract. Due to the inefficiency of the adjuvant therapy, the outcome remains poor in the majority of the repo...

journal_title：Anticancer research

authors： Alavi S,Eckes L,Kratschell R,Taube ET,Rosseck F,Wieners G,Sehouli J

更新日期：2017-05-01 00:00:00

abstract：BACKGROUND:For advanced gastric cancer (AGC) with peritoneal metastasis, decision-making regarding treatment change is often challenging because of the absence of measurable lesions. We attempted to clarify which criterion for treatment change contributes more to longer survival. PATIENTS AND METHODS:We retrospectivel...

journal_title：Anticancer research

authors： Hasegawa H,Fujitani K,Nakazuru S,Hirao M,Yamamoto K,Mita E,Tsujinaka T

更新日期：2014-09-01 00:00:00

abstract：BACKGROUND:The aim of this study was to assess the metallothionein (MT), maintenance protein 2 (Mcm-2) and Ki-67 expressions in adrenocortical adenomas and carcinomas in comparison to normal tissue and evaluate the correlations between these markers of proliferation and between these markers and tumor diameter. MATERI...

journal_title：Anticancer research

authors： Szajerka A,Dziegiel P,Szajerka T,Zabel M,Winowski J,Grzebieniak Z

更新日期：2008-09-01 00:00:00

abstract：BACKGROUND:Colorectal cancer (CRC) is the fifth most common cancer in Africa, with significant differences in incidence, biology and clinical behavior from other populations. MATERIALS AND METHODS:We studied prevalence and clinicopathological features of microsatellite instability (MSI) and young onset CRC in 83 archi...

journal_title：Anticancer research

authors： Irabor DO,Oluwasola OA,Ogunbiyi OJ,Ogun OG,Okolo CA,Melas M,Gruber SB,Shi C,Raskin L

更新日期：2017-05-01 00:00:00

abstract：BACKGROUND:Cancer of the oesophagus is the most common gastrointestinal malignancy in South African blacks. The aim of this study was to determine the reversible and irreversible lipid peroxidation in cancer of the oesophagus; a feature that has not been assessed before in this or other cancer tissue. METHODS:Biopsies...

journal_title：Anticancer research

authors： Levy RD,Oosthuizen MM,Degiannis E,Lambrechts H

更新日期：1998-03-01 00:00:00

abstract：BACKGROUND:The genetic basis of sinonasal inverted papilloma (SNIP)-derived squamous cell carcinoma (SCC) has not yet been well characterized. AIM:To characterize the genetic abnormalities of SNIP and SNIP-derived SCC and to uncover their differences. MATERIALS AND METHODS:Mutations of 409 genes were analyzed using a...

journal_title：Anticancer research

authors： Uchi R,Jiromaru R,Yasumatsu R,Yamamoto H,Hongo T,Manako T,Sato K,Hashimoto K,Wakasaki T,Matsuo M,Nakagawa T

更新日期：2021-01-01 00:00:00

abstract：BACKGROUND:We have previously shown, using the chicken embryo chorioallantoic membrane (CAM) model of in vivo angiogenesis, that X-rays act on the extracellular matrix and enhance normal and tumor-induced angiogenesis. In the present work, we studied the effect of X-rays on the gene expression of three proteins that ar...

journal_title：Anticancer research

authors： Polytarchou C,Gligoris T,Kardamakis D,Kotsaki E,Papadimitriou E

更新日期：2004-09-01 00:00:00

abstract：:We have studied the effects of PAI-1 on the formation of metastasis using human fibrosarcoma cells and DNA transfection. A clone (1-3C), which shows low constitutive expression of PAI-1 and low metastatic potential to the lung, was selected from human fibrosarcoma cell line HT-1080. Newly-derived clones transfected wi...

journal_title：Anticancer research

authors： Tsuchiya H,Sunayama C,Okada G,Matsuda E,Tomita K,Binder BR

更新日期：1997-01-01 00:00:00

abstract：:This review aims to provide insight into treatment of malignant pleural mesothelioma (MPM) considering effects on survival, quality of life (QoL) and costs, in order to determine the value of pemetrexed in MPM treatment. Cisplatin in combination with pemetrexed or raltitrexed increased survival in MPM, whereas vinorel...

journal_title：Anticancer research

authors： Boons CC,VAN Tulder MW,Burgers JA,Beckeringh JJ,Wagner C,Hugtenburg JG

更新日期：2013-09-01 00:00:00

abstract：:Urinary gonadotropin peptide (UGP) has been measured in gynecological and urological cancers, but its usefulness in the diagnosis of cancers of digestive organs has not been investigated. In this report, UGP was measured by sandwich enzyme immunoassay in 311 patients, including 166 patients with cancers of digestive o...

journal_title：Anticancer research

authors： Motoo Y,Watanabe H,Yamaguchi Y,Mouri I,Fujii T,Yamakawa O,Satomura Y,Okai T,Sawabu N

更新日期：1996-07-01 00:00:00

abstract：:We assessed the effect of granulocyte apheresis in patients exhibiting increased granulocyte-to-lymphocyte ratio in order to overcome granulocytosis occurring in the terminal stages of malignancies. 17 patients with post-operative recurrent metastatic tumors including 6 gastric, 3 colonic, 2 rectal, 1 esophageal and 5...

journal_title：Anticancer research

authors： Tabuchi T,Ubukata H,Sato S,Nakata I,Goto Y,Watanabe Y,Hashimoto T,Mizuta T,Adachi M,Soma T

更新日期：1995-05-01 00:00:00

abstract：BACKGROUND:Primary ocular adnexal mucosa-associated lymphoid tissue lymphoma (POAML) is a rare disease. The purpose of this study was to evaluate the treatment outcome and patterns of failure of patients with early-stage POAML treated with radiotherapy. PATIENTS AND METHODS:From 1995 to 2008, 53 patients with early-st...

journal_title：Anticancer research

authors： Ohga S,Nakamura K,Shioyama Y,Sasaki T,Yoshitake T,Atsumi K,Terashima K,Asai K,Matsumoto K,Yoshikawa H,Kawano Y,Honda H

更新日期：2013-12-01 00:00:00

abstract：:The reverse transcriptase polymerase chain reaction (RT-PCR) can be of clinical relevance in identifying malignant melanoma cells in blood or tissues of patients at risk for disseminated melanoma. The diagnostic value of this marker however, is still controversial. The objective of this study was to compare and quanti...

journal_title：Anticancer research

authors： Calogero A,Hospers GA,Timmer-Bosscha H,Koops HS,Mulder NH

更新日期：2000-09-01 00:00:00

abstract：BACKGROUND:Treatment for advanced pancreatic cancer is still very unsatisfactory. Treosulfan is an alkylating agent used for conventional, as well as high-dose chemotherapy regimens, whereby plasma concentrations over 500 μg/ml can be achieved. We investigated the effects of treosulfan on pancreatic cancer cell lines. ...

journal_title：Anticancer research

authors： Nitsch E,Mina S,Brammer I,Pace A,Schuch G,Bokemeyer C,Zander A,Kröger N,Ayuk F

更新日期：2014-04-01 00:00:00

abstract：AIM:To determine the predictive value of HIF-1α and VEGF-C in primary neuroendocrine breast cancers (NEBC) and their correlation with other clinico-pathological characteristics of NEBC. MATERIALS AND METHODS:HIF-1α and VEGF-C were determined immunohistochemically in tissue samples from 31 cases of NEBC. RESULTS:The H...

journal_title：Anticancer research

authors： Marton I,Knezevic F,Ramic S,Milosevic M,Tomas D

更新日期：2012-12-01 00:00:00

abstract：BACKGROUND:The aim of this study was to evaluate the role of radiation therapy alone, employing standard fractionation, in stage III-IV hypopharyngeal carcinoma. MATERIALS AND METHODS:Fourteen (38.9%) stage III and 22 (61.1%) stage IV patients with hypopharyngeal carcinoma were submitted, with curative intent, to excl...

journal_title：Anticancer research

authors： Tombolini V,Santarelli M,Raffetto N,Donato V,Valeriani M,Ferretti A,Enrici RM

更新日期：2004-01-01 00:00:00