Serum matrix metalloproteinase-9 level associated with stromal reaction in patients with gastric cancer.

abstract：:Interferon-alpha (IFN-alpha) has been found to exert multiple enhancing effects in the immune response in vitro, IFN-alpha has been also used in clinical trials with variable response rates. The aim of the present study was to assess the effectiveness of IFN-alpha in the treatment of 25 patients with malignant pleural...

journal_title：Anticancer research

authors： Stathopoulos GP,Baxevanis CN,Papadopoulos NG,Zarkadis IK,Papacostas P,Michailakis E,Tsiatas ML,Papamichail M

更新日期：1996-11-01 00:00:00

abstract：AIM:Mitotane is used in adrenal cancer as adjuvant therapy, monotherapy or combined with other cytotoxic agents in advanced disease, but only 30% of patients respond. The aim of this study was to define the structural requirements for drug activity and to develop analogs with improved adrenalytic action. MATERIALS AND...

journal_title：Anticancer research

authors： Schteingart DE,Sinsheimer JE,Benitez RS,Homan DF,Johnson TD,Counsell RE

更新日期：2012-07-01 00:00:00

abstract：:Two different techniques [reduction of a tetrazolium derivative (MTT) and 3HTdR uptake assays] were compared in order to evaluate the cytotoxic effects of different chemotherapeutic agents in vitro. The cytotoxicities of Melphalan, hexamethylmelamine and seven derivatives, and daunorubicin were measured on P388D1 mous...

journal_title：Anticancer research

authors： Arnould R,Dubois J,Abikhalil F,Libert A,Ghanem G,Atassi G,Hanocq M,Lejeune FJ

更新日期：1990-01-01 00:00:00

abstract：BACKGROUND:Pharmacologically active components of ginseng, particularly protopanaxadiol (PPD)-type ginsenosides, have potent anticancer effects, although their effects on highly malignant glioblastoma multiforme (GBM) have not been systemically evaluated. Identification of effective anticancer ginsenosides and further ...

journal_title：Anticancer research

authors： Wanderi C,Kim E,Chang S,Choi C,Choi K

更新日期：2016-03-01 00:00:00

abstract：:The aim of the study was to investigate tumor suppressor genes (TSGs) which play a role in the pathogenesis of prostate cancer. Additionally, different prostate tumors were immunohistochemically related to their potential precursor cells, the basal cells and the glandular secretory epithelium, which differ in their ho...

journal_title：Anticancer research

authors： Wernert N,Bieroff E,Hügel A

更新日期：1997-07-01 00:00:00

abstract：BACKGROUND:Solar ultraviolet-B (UVB) and vitamin D have been found inversely correlated with cancer incidence, mortality, and survival rates in many studies. MATERIALS AND METHODS:In this work, two sets of cancer data were used: age-adjusted cancer incidence and mortality rates in 2002 for 21 Western developed countri...

journal_title：Anticancer research

authors： Grant WB

更新日期：2006-07-01 00:00:00

abstract：BACKGROUND:The presence of cytokeratin (CK)-positive cells in the bone marrow (BM) of breast cancer patients is an independent prognostic marker for long-term survival. While the exact nature of these cells remains under investigation, their persistence after chemotherapy is linked to decreased survival, making them a ...

journal_title：Anticancer research

authors： Becker S,Becker-Pergola G,Fehm T,Wallwiener D,Solomayer EF

更新日期：2005-05-01 00:00:00

abstract：BACKGROUND/AIM:Several epidemiological studies have reported the chemopreventive potential of biochanin A, in cancer development and progression. We investigated the anticancer potential of combination of biochanin A and temozolomide against U-87 MG and T98 G [glioblastoma multiforme (GBM)] cells. MATERIALS AND METHOD...

journal_title：Anticancer research

authors： Desai V,Jain A,Shaghaghi H,Summer R,Lai JCK,Bhushan A

更新日期：2019-01-01 00:00:00

abstract：:L-Histidinol, a structural analogue of the essential amino acid L-histidine, enhances the toxicity of a variety of anticancer drugs for many tumor cells of animal origin. In this study, the effects of L-histidinol on the proliferation and anticancer drug susceptibility of two human tumor cell lines of lymphoid origin,...

journal_title：Anticancer research

authors： Warrington RC,Cheng I,Zhang L,Fang WD

更新日期：1993-11-01 00:00:00

abstract：BACKGROUND:The aim of this study was to develop and characterize a mouse xenograft model for the hypercalcemic-type of small cell carcinoma of the ovary (HTSCCO). PATIENTS AND METHODS:Tumor fragments were removed from a patient and cultured in six subsequent generations of nude mice. Histology, comparative genomic hyb...

journal_title：Anticancer research

authors： Walt H,Hornung R,Fink D,Dobler-Girdziunaite D,Stallmach T,Spycher MA,Maly F,Haller U,Bürki N

更新日期：2001-09-01 00:00:00

abstract：BACKGROUND/AIM:Seizures represent a major problem for patients with brain metastases. This study evaluated the role of seizures in patients receiving single-fraction radiosurgery (SRS) or multi-fraction stereotactic radiotherapy (FSRT). PATIENTS AND METHODS:This retrospective study included 195 patients receiving SRS ...

journal_title：Anticancer research

authors： Rades D,Witteler J,Kjaer TW,Tvilsted S,Schild SE

更新日期：2020-06-01 00:00:00

abstract：:Four cases of canine lymphoma are presented, including histological examination and cytogenetic investigation. The first case showed a derivative chromosome 13, the second case showed a clonal trisomy 8 and the third case showed a complex karyotype with a clonal trisomy 13 and additional clonal trisomies of the chromo...

journal_title：Anticancer research

authors： Winkler S,Murua Escobar H,Reimann-Berg N,Bullerdiek J,Nolte I

更新日期：2005-11-01 00:00:00

abstract：:Basal level of asparagine synthetase mRNA in BALB3T3 cells was elevated when the cells were shifted from medium containing a high concentration (3.3 mM) of asparagine to one lacking asparagine. We then studied whether the expression of asparagine synthetase mRNA is also mediated through other asparagine-independent si...

journal_title：Anticancer research

authors： Chiyo T,Hongo S,Takeda M

更新日期：1995-09-01 00:00:00

abstract：BACKGROUND:Gold(I) and platinum(II) d(10) and d(8) electronic complexes such as (Au(PPh(2)CH(2)CH(2)PPh(2))(2))Cl and cisplatin, ((H(3)N)(2)PtCl(2)), possess strong antineoplastic activities. Almost no information is available regarding the anticancer activity of isoelectronic silver(I) d(10) complexes. This study exam...

journal_title：Anticancer research

authors： Fourie E,Erasmus E,Swarts JC,Tuchscherer A,Jakob A,Lang H,Joone GK,Van Rensburg CE

更新日期：2012-02-01 00:00:00

abstract：BACKGROUND:The purpose of this study was to examine the efficacy of anticoagulant fondaparinux postoperatively for preventing recurrence after curative resection of colorectal cancer with lymphnode metastasis. PATIENTS AND METHODS:The records of 279 patients who underwent curative resection of colorectal cancer with l...

journal_title：Anticancer research

authors： Yamaoka Y,Ikeda M,Ikenaga M,Murakami H,Haraguchi N,Miyake M,Yamamoto K,Asaoka T,Nishikawa K,Miyamoto A,Miyazaki M,Hirao M,Nakamori S,Sekimoto M

更新日期：2016-10-01 00:00:00

abstract：:Binding of 20-[3H]-phorbol 2, 13-dibutyrate [( 3H] PDB) to intact human K 562 cells was characterized. Specific binding of [3H] PDB to K 562 cells at 20 degrees C or 37 degrees C reached a maximum within 15-20 min. Maximal specific [3H] PDB binding to K 562 cells was followed by a decline (down regulation) of radioact...

journal_title：Anticancer research

authors： Louache F,Villeval JL,Pelicci PG,Rouis M,Titeux M,Henri A,Rochant H,Thomopoulos P,Testa U

更新日期：1984-01-01 00:00:00

abstract：:Vascularized bone graft (VBG) is a form of vascularized bone marrow transplant in which the bone marrow is surgically grafted with its microenvironment intact. Due to the preservation of cellular viability, VBG have significant advantages over non-vascularized bone grafts. Free vascularized fibula grafts have superior...

journal_title：Anticancer research

authors： Muramatsu K,Hashimoto T,Tominaga Y,Taguchi T

更新日期：2014-06-01 00:00:00

abstract：:The insufficient interobserver reproducibility limits the practical use of histomorphological tumor grading in daily routine pathology. In this study, the reasons for the quite low rates of agreement between different observers have been investigated by the application of a factor analytical technique, i.e. principal ...

journal_title：Anticancer research

authors： Sun DQ,Feng CH,Böcking A,Biesterfeld S

更新日期：1994-07-01 00:00:00

abstract：BACKGROUND/AIM:To investigate whether high-dose-rate (HDR) intracavitary brachytherapy (IBT) dose ratios can predict treatment outcomes in patients with stage IIB cervical cancer. PATIENTS AND METHODS:Ninety-three patients treated with weekly cisplatin-based concurrent chemoradiotherapy and HDR IBT were analyzed. Pote...

journal_title：Anticancer research

authors： Cho O,Noh OK,Oh YT,Chang SJ,Chun M

更新日期：2017-01-01 00:00:00

abstract：:We describe herein a brother and sister diagnosed with xeroderma pigmentosum variant (XP-V) in early adult life, who presented with increased sensitivity to sunlight and with cutaneous carcinomas on sun-damaged skin. The 27-year-old male farmer (Case 1.) was diagnosed with advanced squamous cell carcinoma (SCC) and mu...

journal_title：Anticancer research

authors： Somos S,Farkas B,Schneider I

更新日期：1999-05-01 00:00:00

abstract：:The reverse transcriptase polymerase chain reaction (RT-PCR) can be of clinical relevance in identifying malignant melanoma cells in blood or tissues of patients at risk for disseminated melanoma. The diagnostic value of this marker however, is still controversial. The objective of this study was to compare and quanti...

journal_title：Anticancer research

authors： Calogero A,Hospers GA,Timmer-Bosscha H,Koops HS,Mulder NH

更新日期：2000-09-01 00:00:00

abstract：UNLABELLED:The aim of this study was to investigate the apoptosis resulting from NSC 95397, brefeldin A, bortezomib and sanguinarine in neuroendocrine tumor cell lines. MATERIALS AND METHODS:A multiparametric high-content screening assay for measurement of apoptosis was used. The human pancreatic carcinoid cell line, ...

journal_title：Anticancer research

authors： Larsson DE,Wickström M,Hassan S,Oberg K,Granberg D

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND:Angioimmunoblastic T-cell lymphomas (AITLs) are the second most frequent peripheral T-cell lymphomas in humans worldwide and histomorphologically well characterized. MicroRNAs are a group of small non-coding RNAs that can negatively regulate gene expression on a posttranscriptional level. Their dysregulation...

journal_title：Anticancer research

authors： Reddemann K,Gola D,Schillert A,Knief J,Kuempers C,Ribbat-Idel J,Ber S,Schemme J,Bernard V,Gebauer N,Feller AC,Thorns C

更新日期：2015-04-01 00:00:00

abstract：:Squamous cell carcinoma (SCC) is the most common epithelial malignancy in the oral cavity. SCCs and their variants constitute over 90% of oral malignancies, and the disease is associated with poor prognosis. OSCC is a complex malignancy where environmental factors, virus infections, and genetic alterations most likely...

journal_title：Anticancer research

authors： Hillbertz NS,Hirsch JM,Jalouli J,Jalouli MM,Sand L

更新日期：2012-10-01 00:00:00

abstract：BACKGROUND/AIM:γδ T cells mediate cytotoxicity against prostate cancer (PCa) cells in vitro; however, the clinical efficacy of γδ T cell-targeted immunotherapy for recurrent and metastatic PCa is unsatisfactory. We hypothesized that the resistance of recurrent and metastatic PCa to γδ T cells is related to the presence...

journal_title：Anticancer research

authors： Miyashita M,Tomogane M,Nakamura Y,Shimizu T,Fujihara A,Ukimura O,Ashihara E

更新日期：2020-10-01 00:00:00

abstract：AIM:Late oral mucosa changes after radiotherapy for head and neck cancer have been poorly studied. This study aimed to determine long-term effects of radiotherapy on oral mucosa using exfoliative oral cytology. PATIENTS AND METHODS:Fifty patients with cancer were enrolled, five of whom in order to validate microscopic...

journal_title：Anticancer research

authors： Massaro P,Corbella F,DI Liberto R,Paolini A,Pasi F,Tinelli C,DE Silvestri A,Nano R

更新日期：2014-02-01 00:00:00

abstract：BACKGROUND:Genomic imprinting is associated with many human diseases, including various types of cancers, however, no studies on gene imprinting are related to squamous cell carcinoma of the head and neck (SCCHN) directly. MATERIALS AND METHODS:In this study, the expression of a panel of 15 imprinted genes in cancerou...

journal_title：Anticancer research

authors： Hsu CM,Lin PM,Lin HC,Lai CC,Yang CH,Lin SF,Yang MY

更新日期：2016-05-01 00:00:00

abstract：AIM:To clarify how patients with epidermal growth factor receptor (EGFR)-mutant lung adenocarcinoma with acquired resistance to EGFR-tyrosine kinase inhibitors (TKIs) respond to radiotherapy (RT) for brain metastases. PATIENTS AND METHODS:Forty-seven patients were divided into the following three groups: a TKI-naïve g...

journal_title：Anticancer research

authors： Hirata H,Nakamura K,Kunitake N,Shioyama Y,Sasaki T,Ohga S,Nonoshita T,Yoshitake T,Asai K,Inoue K,Nagashima A,Ono M,Honda H

更新日期：2013-04-01 00:00:00

abstract：UNLABELLED:The pharmacology of progestins includes actions initiated by various cellular targets, including classic receptors characterized as nuclear transcription factors (nPR), G-protein-coupled membrane receptors (mPR), enzymes, membrane channels and transporters. The effects initiated by targets other than nPR are...

journal_title：Anticancer research

authors： Fjelldal R,Moe BT,Ørbo A,Sager G

更新日期：2010-12-01 00:00:00

abstract：AIM:Despite recent improvements in treatment strategies, the results of chemotherapy in patients with advanced squamous cell carcinoma of the larynx are not satisfactory. Thus, the development of new approaches which influence specific metabolic pathways are needed. In the last decade, evidence has emerged implicating ...

journal_title：Anticancer research

authors： Stepulak A,Luksch H,Uckermann O,Sifringer M,Rzeski W,Polberg K,Kupisz K,Klatka J,Kielbus M,Grabarska A,Marzahn J,Turski L,Ikonomidou C

更新日期：2011-02-01 00:00:00