Abstract：
:This study isolated and identified the lutein-enriching microalga Chlorella sorokiniana FZU60. Different types of media and concentrations of sodium acetate and nitrate were evaluated to improve mixotrophic growth and lutein production. Highest lutein content, production, and productivity were obtained in BG11 medium with 1 g/L acetate and 0.75 g/L nitrate. Additionally, pulse feeding with 1 g/L acetate every 48 h led to the alternation between mixotrophy and photoinduction, resulting in a lutein production of 33.6 mg/L. Most notably, excellent lutein content (9.57 mg/g) and productivity (11.57 mg/L/d) were obtained using a new multi-operation integrated strategy, and the achieved levels exceed those reported in most related studies. This work demonstrates the synergistic integration of simple and effective strategies for the enhancement of lutein production in the indigenous microalga C. sorokiniana FZU60 and provides new insight into the highly efficient microalgae-based lutein production.
journal_name
Bioresour Technoljournal_title
Bioresource technologyauthors
Xie Y,Li J,Ma R,Ho SH,Shi X,Liu L,Chen Jdoi
10.1016/j.biortech.2019.121798subject
Has Abstractpub_date
2019-10-01 00:00:00pages
121798eissn
0960-8524issn
1873-2976pii
S0960-8524(19)31028-4journal_volume
290pub_type
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