Mechanisms and effects of arsanilic acid on antibiotic resistance genes and microbial communities during pig manure digestion.

Abstract:

:High concentrations of residual arsanilic acid occur in pig manure due to its use in feed to promote growth and control diseases. This study compared the effects of arsanilic acid at three concentrations (0, 325, and 650mg/kg dry pig manure) on the abundance of antibiotic resistance genes (ARGs) and the microbial community during anaerobic digestion. Addition of 650mg/kg arsanilic acid enhanced the absolute abundances of tetC, sul2, ermB, and gyrA more than twofold in the digestion product. Redundancy analysis indicated that the change in the microbial community structure was the main driver of variation in the ARGs profile. The As resistance gene arsC co-occurred with four ARGs and intI1, possibly causing the increase in ARGs under pressure by arsanilic acid. High arsanilic acid concentrations can increase the risk of ARGs occurring in anaerobic digestion products. The amount of arsanilic acid used as a feed additive should be controlled.

journal_name

Bioresour Technol

journal_title

Bioresource technology

authors

Sun W,Qian X,Gu J,Wang XJ,Zhang L,Guo AY

doi

10.1016/j.biortech.2017.03.025

subject

Has Abstract

pub_date

2017-06-01 00:00:00

pages

217-223

eissn

0960-8524

issn

1873-2976

pii

S0960-8524(17)30295-X

journal_volume

234

pub_type

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