Hormone-dependent aggression in male rats is proportional to serum testosterone concentration but sexual behavior is not.

Abstract:

:Male hooded rats were castrated and implanted with Silastic capsules (1.57 mm i.d.; 3.18 mm o.d.) having a testosterone-filled space 0, 7, 22, 60, or 90 mm long. All animals were returned to their original group cages for a three-week period to allow hormone concentrations and behavioral tendencies to stabilize. Each male was then housed with an intact female in a large cage. Aggression by the male toward an unfamiliar male was tested at weekly intervals for three weeks. Sexual behavior with an estrogen/progesterone-primed ovariectomized female was tested on each of the subsequent two weeks. Serum testosterone was measured during the following week. The frequency of aggression was correlated with serum testosterone concentration up to the normal level and did not increase with higher serum testosterone concentrations. In contrast, sexual behavior was virtually absent in animals with no testosterone replacement and normal in all other groups. These results demonstrate a clear dissociation in the dependence of hormone-dependent aggression and sexual behavior on serum testosterone concentration. In a male cohabiting with a female, sexual experience activates hormone-dependent aggression toward an unfamiliar male but the level of aggression that develops depends on the serum testosterone concentration in the resident male.

journal_name

Physiol Behav

journal_title

Physiology & behavior

authors

Albert DJ,Jonik RH,Watson NV,Gorzalka BB,Walsh ML

doi

10.1016/0031-9384(90)90336-3

subject

Has Abstract

pub_date

1990-09-01 00:00:00

pages

409-16

issue

3

eissn

0031-9384

issn

1873-507X

pii

0031-9384(90)90336-3

journal_volume

48

pub_type

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