Abstract：
:With the recent development of integrated positron emission tomography-magnetic resonance imaging (PET-MRI) scanners, new possibilities for quantitative molecular imaging of cancer are realized. However, the practical advantages and potential clinical benefits of the ability to record PET and MRI data simultaneously must be balanced against the substantial costs and other requirements of such devices. In this review, we highlight several of the key areas where integrated PET-MRI measurements, obtained simultaneously, are anticipated to have a significant impact on clinical and/or research studies. These areas include the use of MR-based motion corrections and/or a priori anatomical information for improved reconstruction of PET data, improved arterial input function characterization for PET kinetic modeling, the use of dual-modality contrast agents, and patient comfort and practical convenience. For widespread acceptance, a compelling case could be made if the combination of quantitative MRI and specific PET biomarkers significantly improves our ability to assess tumor status and response to therapy, and some likely candidates are now emerging. We consider the relative advantages and disadvantages afforded by PET-MRI and summarize current opinions and evidence as to the likely value of PET-MRI in the management of cancer.
journal_name
Magn Reson Imagingjournal_title
Magnetic resonance imagingauthors
Yankeelov TE,Peterson TE,Abramson RG,Izquierdo-Garcia D,Arlinghaus LR,Li X,Atuegwu NC,Catana C,Manning HC,Fayad ZA,Gore JCdoi
10.1016/j.mri.2012.06.001subject
Has Abstractpub_date
2012-11-01 00:00:00pages
1342-56issue
9eissn
0730-725Xissn
1873-5894pii
S0730-725X(12)00199-3journal_volume
30pub_type
杂志文章,评审abstract：PURPOSE:To present preliminary, in vivo temperature measurements during MRI of a pig implanted with a deep brain stimulation (DBS) system. MATERIALS AND METHODS:DBS system (Medtronic Inc., Minneapolis, MN) was implanted in the brain of an anesthetized pig. 3.0-T MRI was performed with a T/R head coil using the low-SAR...
journal_title：Magnetic resonance imaging
pub_type： 杂志文章
doi：10.1016/j.mri.2012.11.005
更新日期：2013-06-01 00:00:00
abstract：:Type A acute aortic dissection (TAAAD) sometimes presents with acute stroke-like symptoms. When intravenous tissue plasminogen activator (IV-tPA) therapy is considered for acute ischemic stroke, TAAAD must be excluded. Painless TAAAD presenting with acute stroke may be easily missed. Two cases of painless TAAAD presen...
journal_title：Magnetic resonance imaging
pub_type： 杂志文章
doi：10.1016/j.mri.2016.04.021
更新日期：2016-09-01 00:00:00
abstract：:Quantitative processing of NMR relaxation images depends on the characteristics of the used fitting algorithm. Therefore several common fitting algorithms are compared for decay curves with low signal-to-noise ratios. The use of magnitude data yields a non-zero base line, and is shown to result in an overestimation of...
journal_title：Magnetic resonance imaging
pub_type： 杂志文章
doi：10.1016/s0730-725x(00)00200-9
更新日期：2000-11-01 00:00:00
abstract：:Qualitative and quantitative proton magnetic resonance imaging techniques were applied to persimmon (Diospyros kaki cv 'Fuyu') fruit during development and post-harvest ripening. Spin-lattice (T(1)) relaxation times in mesocarp parenchyma and vascular tissue exhibited a sigmoidal pattern of increase leading to commerc...
journal_title：Magnetic resonance imaging
pub_type： 杂志文章
doi：10.1016/s0730-725x(03)00082-1
更新日期：2003-07-01 00:00:00
abstract：OBJECTIVE:To test if three-dimensional (3D) cine spatial frequency-temporal frequency Broad-use Linear Acquisition Speed-up Technique (k-t BLAST) is suitable for rapid evaluation of global and regional left ventricular (LV) functional parameters and to evaluate the influence of gadolinium administration. MATERIALS AND...
journal_title：Magnetic resonance imaging
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doi：10.1016/j.mri.2008.01.027
更新日期：2008-07-01 00:00:00
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journal_title：Magnetic resonance imaging
pub_type： 杂志文章
doi：10.1016/j.mri.2012.06.036
更新日期：2013-02-01 00:00:00
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journal_title：Magnetic resonance imaging
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doi：10.1016/j.mri.2015.07.010
更新日期：2016-01-01 00:00:00
abstract：:Surface modification of liposomes containing Gd-diethylenetriaminepentaacetyl-phosphatidylethanolamine (Gd-DTPA-PE) as an amphiphilic paramagnetic label influences their contrast properties as MRI agents. Liposomes with the mean diameter ca. 220 nm and 10% mol content of Gd-DTPA-PE were modified with dextran (molecula...
journal_title：Magnetic resonance imaging
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更新日期：1995-01-01 00:00:00
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journal_title：Magnetic resonance imaging
pub_type： 杂志文章
doi：10.1016/j.mri.2012.06.037
更新日期：2013-02-01 00:00:00
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journal_title：Magnetic resonance imaging
pub_type： 杂志文章
doi：10.1016/j.mri.2005.05.001
更新日期：2005-07-01 00:00:00
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pub_type： 杂志文章
doi：10.1016/j.mri.2020.11.008
更新日期：2021-02-01 00:00:00
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journal_title：Magnetic resonance imaging
pub_type： 杂志文章
doi：10.1016/j.mri.2014.08.028
更新日期：2015-01-01 00:00:00
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journal_title：Magnetic resonance imaging
pub_type： 杂志文章
doi：10.1016/0730-725x(90)90242-t
更新日期：1990-01-01 00:00:00
abstract：:The objective of this study was to describe magnetic resonance (MR) findings with a 1.5T imager for hepatic parenchymal changes after proton beam radiotherapy. Thirty-two patients who received proton radiotherapy with doses of 50-87 Gy underwent MR imaging 1-75 months (mean 22 months) after the start of irradiation. A...
journal_title：Magnetic resonance imaging
pub_type： 杂志文章
doi：10.1016/s0730-725x(00)00152-1
更新日期：2000-07-01 00:00:00
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journal_title：Magnetic resonance imaging
pub_type： 杂志文章
doi：10.1016/j.mri.2008.01.023
更新日期：2008-10-01 00:00:00
abstract：:In this study, magnetic resonance imaging (MRI) was used to dynamically visualize the diffusion process of CO2 in porous media saturated with liquid hydrocarbon. Based on the assumption of semi-infinite media, effective CO2 diffusivity was obtained directly by the nonlinear fitting of one MR profile during the diffusi...
journal_title：Magnetic resonance imaging
pub_type： 杂志文章
doi：10.1016/j.mri.2015.12.024
更新日期：2016-05-01 00:00:00
abstract：:Diffusion tensor imaging (DTI) was used to investigate the involvement of brain white matter in Williams syndrome (WS), a genetic neurodevelopmental disorder. Whole-brain DTIs were obtained from 16 young adults with WS and 16 normal controls. A voxel-based analysis was performed to compare fractional anisotropy (FA) v...
journal_title：Magnetic resonance imaging
pub_type： 杂志文章
doi：10.1016/j.mri.2011.07.012
更新日期：2011-11-01 00:00:00
abstract：:The aim of this work is to present and evaluate a level-set segmentation approach with vesselness-dependent anisotropic energy weights, which focuses on the exact segmentation of malformed as well as small vessels from time-of-flight (TOF) magnetic resonance angiography (MRA) datasets. In a first step, a vesselness fi...
journal_title：Magnetic resonance imaging
pub_type： 杂志文章
doi：10.1016/j.mri.2012.07.008
更新日期：2013-02-01 00:00:00
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journal_title：Magnetic resonance imaging
pub_type： 杂志文章
doi：10.1016/j.mri.2007.08.010
更新日期：2008-04-01 00:00:00
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journal_title：Magnetic resonance imaging
pub_type： 杂志文章
doi：10.1016/j.mri.2012.02.019
更新日期：2012-09-01 00:00:00
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journal_title：Magnetic resonance imaging
pub_type： 杂志文章
doi：10.1016/j.mri.2005.12.013
更新日期：2006-06-01 00:00:00
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journal_title：Magnetic resonance imaging
pub_type： 杂志文章
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更新日期：2020-01-01 00:00:00
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journal_title：Magnetic resonance imaging
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更新日期：2019-06-01 00:00:00
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journal_title：Magnetic resonance imaging
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abstract：:Positive contrast imaging methods produce enhanced signal at large magnetic field gradient in magnetic resonance imaging. Several postprocessing algorithms, such as susceptibility gradient mapping and phase gradient mapping methods, have been applied for positive contrast generation to detect the cells targeted by sup...
journal_title：Magnetic resonance imaging
pub_type： 杂志文章
doi：10.1016/j.mri.2011.04.011
更新日期：2011-09-01 00:00:00
abstract：:This work discusses the effect of sampling time on noise, signal-to-noise and contrast-to-noise ratios in magnetic resonance imaging. A simple imaging experiment is performed to demonstrate the effect of sampling time on noise, confirming theoretical expectations that doubling the sampling time while decreasing the re...
journal_title：Magnetic resonance imaging
pub_type： 杂志文章
doi：10.1016/0730-725x(87)90481-4
更新日期：1987-01-01 00:00:00
abstract：:Diffusion tensor magnetic resonance imaging (DTI) is useful for studying the microstructural changes in the spinal cord following traumatic injury; however, image quality is generally poor due to the small size of the spinal cord, physiological motion and susceptibility artifacts. Self-navigated, interleaved, variable...
journal_title：Magnetic resonance imaging
pub_type： 杂志文章
doi：10.1016/j.mri.2010.06.006
更新日期：2010-11-01 00:00:00
abstract：PURPOSE:To determine the diagnostic performance of diffusion-weighted MRI and MR volumetry for the assessment of tumor response after preoperative chemoradiotherapy (CRT) in patients with locally advanced rectal cancer. MATERIALS AND METHODS:Forty-three patients with rectal cancer who underwent preoperative CRT were p...
journal_title：Magnetic resonance imaging
pub_type： 杂志文章
doi：10.1016/j.mri.2014.08.041
更新日期：2015-02-01 00:00:00
abstract：:Although there is ample evidence in the literature for structural, functional and physiological asymmetries in the two hemispheres of human brain, direct evidence of a similar asymmetry in the in vivo distribution of brain metabolites has been lacking. In this study, the existence of chemical asymmetries in six differ...
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doi：10.1016/s0730-725x(96)00342-6
更新日期：1997-01-01 00:00:00
