Candida infections in solid organ transplantation: Guidelines from the American Society of Transplantation Infectious Diseases Community of Practice.

Abstract:

:These updated guidelines from the American Society of Transplantation Infectious Diseases Community of Practice provide recommendations for the diagnosis and management of Candida infections in solid organ transplant recipients. Candida infections manifest primarily as candidemia and invasive candidiasis and cause considerable morbidity and mortality. Early diagnosis and initiation of treatment are necessary to reduce mortality. For both candidemia and invasive candidiasis, an echinocandin is recommended for initial therapy. However, early transition to oral therapy is encouraged when patients are stable and the organism is susceptible. Candida prophylaxis should be targeted for high-risk patients in liver, small bowel, and pancreas transplant recipients. Future research should address which patient groups may benefit most from preventative antifungal therapy strategies.

journal_name

Clin Transplant

journal_title

Clinical transplantation

authors

Aslam S,Rotstein C,AST Infectious Disease Community of Practice.

doi

10.1111/ctr.13623

subject

Has Abstract

pub_date

2019-09-01 00:00:00

pages

e13623

issue

9

eissn

0902-0063

issn

1399-0012

journal_volume

33

pub_type

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