Perspectives on donor lung allocation from both sides of the Atlantic: The United States.

Abstract:

:Donor lung allocation in the United States focuses on decreasing waitlist mortality and improving recipient outcomes. The implementation of allocation policy to match deceased donor lungs to waitlisted patients occurs through a unique partnership between government and private organizations, namely the Organ Procurement and Transplantation Network under the Department of Health and Human Services and the United Network for Organ Sharing. In 2005, the donor lung allocation algorithm shifted toward the prioritization of medical urgency of waitlisted patients instead of time accrued on the waitlist. This led to the Lung Allocation Score, which weighs over a dozen clinical variables to predict a 1-year estimate of survival benefit, and is used to prioritize waitlisted patients. In 2017, the use of local allocation boundaries was eliminated in favor of a 250 nautical mile radius from the donor hospital as the first unit of distance used in allocation. The next upcoming iteration of donor allocation policy is expected to use a continuous distribution algorithm where all geographic boundaries are eliminated. There are additional opportunities to improve donor lung allocation, such as for patients with high antibody titers with access to a limited number of donors.

journal_name

Clin Transplant

journal_title

Clinical transplantation

authors

Tsuang WM,Snyder LD,Budev MM

doi

10.1111/ctr.13873

subject

Has Abstract

pub_date

2020-07-01 00:00:00

pages

e13873

issue

7

eissn

0902-0063

issn

1399-0012

journal_volume

34

pub_type

杂志文章
  • Kidney transplant referral practices in southeastern dialysis units.

    abstract:BACKGROUND:The Southeastern Kidney Transplant Coalition was created in 2010 to improve kidney transplant (KTx) rates in Georgia, North Carolina, and South Carolina. To identify dialysis staff-reported barriers to transplant, the Coalition developed a survey of dialysis providers in the region. METHODS:All dialysis uni...

    journal_title:Clinical transplantation

    pub_type: 杂志文章

    doi:10.1111/ctr.12693

    authors: Browne T,Patzer RE,Gander J,Amamoo MA,Krisher J,Sauls L,Pastan S

    更新日期:2016-04-01 00:00:00

  • Renal transplant recipient attitudes toward steroid use and steroid withdrawal.

    abstract::Although steroid avoidance and withdrawal in renal transplant recipients (RTR) are actively being evaluated by physicians, the attitudes of recipients toward steroid use have not been systematically studied in the modern era. We conducted a confidential written survey of single-organ adult RTR pertaining to prednisone...

    journal_title:Clinical transplantation

    pub_type: 杂志文章

    doi:10.1034/j.1399-0012.2003.00034.x

    authors: Prasad GV,Nash MM,McFarlane PA,Zaltzman JS

    更新日期:2003-04-01 00:00:00

  • Influence of anti-rejection therapy on the timing of cytomegalovirus disease and other infections in renal transplant recipients.

    abstract::Infections are an important cause of mortality and morbidity in renal transplant recipients. To study the impact of anti-rejection therapy on the timing of infections, the records of 599 consecutive renal transplants, performed prior to 31 December 1996 at the Royal Melbourne Hospital, were reviewed. Patients were gro...

    journal_title:Clinical transplantation

    pub_type: 杂志文章

    doi:10.1034/j.1399-0012.2000.140104.x

    authors: Jamil B,Nicholls KM,Becker GJ,Walker RG

    更新日期:2000-02-01 00:00:00

  • Report of National Kidney Foundation Consensus Conference to Decrease Kidney Discards.

    abstract::The organ shortage is one of the major challenges in the field of organ transplantation, yet the percentage of kidneys procured and discarded prior to transplantation has continued to rise to twenty percent. The causes of organ discard are complex, yet an urgent need exists for collaborative efforts to maximize the ut...

    journal_title:Clinical transplantation

    pub_type: 杂志文章

    doi:10.1111/ctr.13419

    authors: Cooper M,Formica R,Friedewald J,Hirose R,O'Connor K,Mohan S,Schold J,Axelrod D,Pastan S

    更新日期:2019-01-01 00:00:00

  • Predicting and preventing readmissions in kidney transplant recipients.

    abstract::A lack of research exploring post-transplant process optimization to reduce readmissions and increasing readmission rates at our center from 2009 to 2013 led to this study, aimed at assessing the effect of patient and process factors on 30-d readmission rates after kidney transplantation. This was a retrospective case...

    journal_title:Clinical transplantation

    pub_type: 杂志文章

    doi:10.1111/ctr.12748

    authors: Covert KL,Fleming JN,Staino C,Casale JP,Boyle KM,Pilch NA,Meadows HB,Mardis CR,McGillicuddy JW,Nadig S,Bratton CF,Chavin KD,Baliga PK,Taber DJ

    更新日期:2016-07-01 00:00:00

  • Extracorporeal membrane oxygenation as a bridge vs. non-bridging for lung transplantation: A systematic review and meta-analysis.

    abstract::Whether extracorporeal membrane oxygenation (ECMO) as a bridge to lung transplantation (BTT) can achieve a similar survival to non-BTT remains controversial. We conducted this meta-analysis to compare the outcomes between ECMO BTT and non-BTT to facilitate better clinical decision-making. Seven databases were searched...

    journal_title:Clinical transplantation

    pub_type: 杂志文章

    doi:10.1111/ctr.14157

    authors: Wan X,Bian T,Ye S,Cai P,Yu Z,Zhu J,Zhang W

    更新日期:2020-11-22 00:00:00

  • Ethnicity, medical insurance, and living kidney donation.

    abstract:BACKGROUND:Relationships between race/ethnicity, recipient medical insurance, and living donor kidney transplantation (LKT) are incompletely described. METHODS:Associations between medical insurance and LKT were assessed in 447 recipients at a southeastern US transplant center. Primary and secondary payers were includ...

    journal_title:Clinical transplantation

    pub_type: 杂志文章

    doi:10.1111/ctr.12168

    authors: Reeves-Daniel AM,Farney AC,Fletcher AJ,Assimos D,Westcott C,Rogers J,Stratta RJ,Rocco MV,Freedman BI

    更新日期:2013-07-01 00:00:00

  • Overview of reduced-size liver transplantation.

    abstract::Organ donor availability is the major limiting factor in pediatric liver transplantation, and many children succumb from their liver disease before a suitable donor can be found. In an attempt to overcome this shortage, reduced-size liver transplantation, split liver transplantation, and living-donor liver transplanta...

    journal_title:Clinical transplantation

    pub_type: 杂志文章,评审

    doi:

    authors: Emond JC,Whitington PF,Broelsch CE

    更新日期:1991-04-01 00:00:00

  • Renal transplantation offers a better survival in HCV-infected ESRD patients.

    abstract::Sezer S, Ozdemir FN, Akcay A, Arat Z, Boyacioglu S, Haberal M. Renal transplantation offers a better survival in HCV-infected ESRD patients. Clin Transplant 2004 DOI: 10.1111/j.1399-0012.2004.00252. Abstract: The presence of hepatitis C virus (HCV) infection has been found to adversely affect the morbidity and mortali...

    journal_title:Clinical transplantation

    pub_type: 杂志文章

    doi:10.1111/j.1399-0012.2004.00252.x

    authors: Sezer S,Ozdemir FN,Akcay A,Arat Z,Boyacioglu S,Haberal M

    更新日期:2004-10-01 00:00:00

  • Use of enteric-coated mycophenolate sodium in liver transplant patients with intestinal intolerance caused by mycophenolate mofetil.

    abstract:BACKGROUND:Post-transplant gastrointestinal (GI) side effects can impair a patient's quality of life (QoL). This study investigates the improvement in GI side effects and related QoL changes in recipients of liver transplantation (OLT) after converting patients from mycophenolate mofetil (MMF) to enteric-coated mycophe...

    journal_title:Clinical transplantation

    pub_type: 临床试验,杂志文章

    doi:10.1111/j.1399-0012.2009.01019.x

    authors: Doria C,Ramirez CB,Frank AM,Vaccino S,Fraser N,Marino IR

    更新日期:2009-11-01 00:00:00

  • Indications and outcomes of pancreatic surgery after liver transplantation.

    abstract:BACKGROUND:Prior liver transplantation and immunosuppression potentially translate into significant morbidity and poor outcomes after any type of pancreatic surgery. Little is known about the outcomes of pancreatic surgery after liver transplantation. This study was designed to review our experience regarding the indic...

    journal_title:Clinical transplantation

    pub_type: 杂志文章

    doi:10.1111/ctr.12317

    authors: Mejia J,Sucandy I,Steel J,Golas B,Humar A,Lee K,Zeh H,Marsh J,Tsung A

    更新日期:2014-03-01 00:00:00

  • Use of G-CSF-stimulated marrow in allogeneic hematopoietic stem cell transplantation settings: a comprehensive review.

    abstract::In recent years, several researchers have unraveled the previously unrecognized effects of granulocyte colony-stimulating factor (G-CSF) on hematopoiesis and the immune cell functions of bone marrow in healthy donors. In human leukocyte antigen-matched or haploidentical transplant settings, available data have establi...

    journal_title:Clinical transplantation

    pub_type: 杂志文章,评审

    doi:10.1111/j.1399-0012.2010.01298.x

    authors: Chang YJ,Huang XJ

    更新日期:2011-01-01 00:00:00

  • Diffuse large B-cell lymphoma in a renal allograft associated with Epstein-Barr virus in the recipient: a case report and a review of lymphomas presenting in a transplanted kidney.

    abstract::The purpose of this review was to evaluate the case reports with lymphoproliferative disorders exclusively localized in the allograft transplanted kidney. We also report a rare case of diffuse large B-cell lymphoma originated from the lymphocytes of the recipient with exclusive localization in the kidney allograft. We...

    journal_title:Clinical transplantation

    pub_type: 杂志文章

    doi:10.1111/j.1399-0012.2008.00804.x

    authors: Cobo F,García C,Talavera P,Ruiz-Cabello F,Bravo J,Concha A

    更新日期:2008-07-01 00:00:00

  • Hospital admissions and emergency department visits among kidney transplant recipients.

    abstract::Reducing acute care utilization is a means of improving long-term patient outcomes. We sought to assess high inpatient (IP) admission and standalone emergency department (ED) utilization within a 9-month period post-kidney transplantation and to identify mutable factors to reduce utilization. In this ten-year retrospe...

    journal_title:Clinical transplantation

    pub_type: 临床试验,杂志文章

    doi:10.1111/ctr.13522

    authors: Weeda ER,Su Z,Taber DJ,Bian J,Morinelli TA,Pilch NA,Mauldin PD,DuBay DA

    更新日期:2019-05-01 00:00:00

  • Adherence to a pedometer-based physical activity intervention following kidney transplant and impact on metabolic parameters.

    abstract::The majority of kidney transplant recipients die from cardiovascular events. Physical activity may be a modifiable risk factor for cardiovascular disease following transplant. The goal of our study was to examine adherence to a physical activity intervention following kidney transplant and its impact on metabolic para...

    journal_title:Clinical transplantation

    pub_type: 杂志文章

    doi:10.1111/ctr.12553

    authors: Lorenz EC,Amer H,Dean PG,Stegall MD,Cosio FG,Cheville AL

    更新日期:2015-06-01 00:00:00

  • Sirolimus use and incidence of venous thromboembolism in cardiac transplant recipients.

    abstract::Sirolimus is an immunosuppressive agent increasingly used in cardiac transplant recipients in the setting of allograft vasculopathy or worsening renal function. Recently, sirolimus has been associated with increased risk of venous thromboembolism (VTE) in lung transplant recipients. To investigate whether this associa...

    journal_title:Clinical transplantation

    pub_type: 临床试验,杂志文章

    doi:10.1111/j.1399-0012.2012.01677.x

    authors: Thibodeau JT,Mishkin JD,Patel PC,Kaiser PA,Ayers CR,Mammen PP,Markham DW,Ring WS,Peltz M,Drazner MH

    更新日期:2012-11-01 00:00:00

  • Renal allograft outcomes following early corticosteroid withdrawal in Hispanic transplant recipients.

    abstract:BACKGROUND:Renal transplant outcomes in Hispanics have been conflicting regarding acute rejection (AR) and allograft survival. Additionally, the feasibility of early corticosteroid withdrawal (ECW) regimens among Hispanics has not been adequately addressed. The purpose of this study is to report outcomes following ECW ...

    journal_title:Clinical transplantation

    pub_type: 杂志文章

    doi:10.1111/ctr.12218

    authors: Afaneh C,Cheng E,Aull MJ,Watkins AC,Kim J,Leeser DB,Kapur S

    更新日期:2013-11-01 00:00:00

  • Mycobacterium tuberculosis after solid organ transplantation: A review of more than 2000 cases.

    abstract:BACKGROUND:Mycobacterium tuberculosis (TB) is a common pathogen worldwide, and it may cause significant infection after solid organ transplantation (SOT). We reviewed all reported TB cases to provide an update on its epidemiology, clinical presentation, management, and outcome after SOT. METHODS:MEDLINE, EMBASE, and O...

    journal_title:Clinical transplantation

    pub_type: 杂志文章,评审

    doi:10.1111/ctr.13259

    authors: Abad CLR,Razonable RR

    更新日期:2018-06-01 00:00:00

  • Outcome of kidney transplant in primary, repeat, and kidney-after-nonrenal solid-organ transplantation: 15-year analysis of recent UNOS database.

    abstract::The number of nonrenal solid-organ transplants increased substantially in the last few decades. Many of these patients develop renal failure and receive kidney transplantation. The aim of this study was to evaluate patient and kidney allograft survival in primary, repeat, and kidney-after-nonrenal organ transplantatio...

    journal_title:Clinical transplantation

    pub_type: 杂志文章

    doi:10.1111/ctr.13108

    authors: El-Husseini A,Aghil A,Ramirez J,Sawaya B,Rajagopalan N,Baz M,Mei X,Davenport DL,Gedaly R

    更新日期:2017-11-01 00:00:00

  • Risk factors for acute renal failure requiring dialysis after liver transplantation.

    abstract::Acute renal failure (ARF) is a common and severe complication after liver transplantation (LT). The aim of this study was to ascertain the impact of ARF requiring dialysis in the outcome of LT and to analyze the risk factors leading to this event in the early post-operative period. From October 1988 to December 1994, ...

    journal_title:Clinical transplantation

    pub_type: 杂志文章

    doi:

    authors: Bilbao I,Charco R,Balsells J,Lazaro JL,Hidalgo E,Llopart L,Murio E,Margarit C

    更新日期:1998-04-01 00:00:00

  • Development of the living donation and kidney transplantation information made easy (KidneyTIME) educational animations.

    abstract:BACKGROUND:Current web-based educational approaches about living kidney donation (LKD) are complex, lengthy, and/or text-laden, which may impair accurate interpretation of information, thereby limiting kidney transplant access. PURPOSE:This paper describes the process of developing animation-based LKD education design...

    journal_title:Clinical transplantation

    pub_type: 杂志文章

    doi:10.1111/ctr.13830

    authors: Kayler LK,Dolph B,Seibert R,Keller M,Cadzow R,Feeley TH

    更新日期:2020-04-01 00:00:00

  • Role of pre-transplant marital status in renal transplant outcome.

    abstract:BACKGROUND:End-stage renal disease is associated with illness-induced disruptions that challenge patients and their families to accommodate and adapt. However, the impact of patients' marital status on kidney transplant outcome has never been studied. This project, based on data from United States Renal Data System (US...

    journal_title:Clinical transplantation

    pub_type: 杂志文章

    doi:10.1111/j.1399-0012.2006.00575.x

    authors: Naiman N,Baird BC,Isaacs RB,Koford JK,Habib AN,Wang BJ,Barenbaum LL,Goldfarb-Rumyantzev AS

    更新日期:2007-01-01 00:00:00

  • Liver cell transplantation in children.

    abstract::With increasing shortage of donor organs and changes in organ allocation systems, there is a considerable need for alternative or supportive techniques in the field of liver transplantation. Liver cell transplantation (LCT) is such an innovative technique that is especially promising for use in children, because it is...

    journal_title:Clinical transplantation

    pub_type: 杂志文章,评审

    doi:10.1111/j.1399-0012.2009.01113.x

    authors: Meyburg J,Schmidt J,Hoffmann GF

    更新日期:2009-12-01 00:00:00

  • The international prevalence and variability of nonadherence to the nonpharmacologic treatment regimen after heart transplantation: Findings from the cross-sectional BRIGHT study.

    abstract:INTRODUCTION:Heart transplant (HTx) recipients need to follow a complex therapeutic regimen. We assessed the international prevalence and variability in nonadherence to six nonpharmacologic treatment components (physical activity, sun protection, diet, alcohol use, nonsmoking, and outpatient follow-up visits). METHODS...

    journal_title:Clinical transplantation

    pub_type: 杂志文章

    doi:10.1111/ctr.13280

    authors: Helmy R,Duerinckx N,De Geest S,Denhaerynck K,Berben L,Russell CL,Van Cleemput J,Crespo-Leiro MG,Dobbels F,BRIGHT study team.

    更新日期:2018-07-01 00:00:00

  • Micafungin as antifungal prophylaxis in recipients of allogeneic hematopoietic stem cell transplantation: results of different dosage levels in clinical practice.

    abstract::Micafungin has been approved for the prophylaxis of Candida infections in patients undergoing allogeneic hematopoietic stem cell transplantation (allo-HSCT). Here, we report a single-center experience of three different dose levels regarding efficacy, toxicity, and colonization with Candida ssp. in clinical practice. ...

    journal_title:Clinical transplantation

    pub_type: 杂志文章

    doi:10.1111/ctr.12310

    authors: Langebrake C,Rohde H,Lellek H,Wolschke C,Kröger NM

    更新日期:2014-03-01 00:00:00

  • Social support and immunosuppressant therapy adherence among adult renal transplant recipients.

    abstract:BACKGROUND:The purpose of the study was to assess the relationship between social support and immunosuppressant therapy adherence among adult renal transplant recipients. METHODS:A cross-sectional, survey design was employed. Mailed questionnaires were used to collect data from 81 recipients, and included the Immunosu...

    journal_title:Clinical transplantation

    pub_type: 杂志文章

    doi:10.1111/j.1399-0012.2009.01060.x

    authors: Chisholm-Burns MA,Spivey CA,Wilks SE

    更新日期:2010-05-01 00:00:00

  • Disparity in access to kidney allograft offers among transplant candidates with human immunodeficiency virus.

    abstract:BACKGROUND:Despite a survival benefit from transplantation and acceptable outcomes, patients with human immunodeficiency virus (HIV+) face barriers to kidney transplantation. Little is known about the acceptance or decline of organ offers on their behalf because waitlist registry data do not include HIV serostatus. ME...

    journal_title:Clinical transplantation

    pub_type: 杂志文章

    doi:10.1111/ctr.13466

    authors: Cohen JB,Locke JE,Shelton B,Reed RD,Mustian M,MacLennan P,Forde KA,Reese PP,Sawinski D

    更新日期:2019-02-01 00:00:00

  • Late acute rejection after liver transplantation impacts patient survival.

    abstract::Hepatic allograft rejection still remains an important problem following liver transplantation. Early acute rejection, occurring within three months of transplant, is a common event and usually of lesser significance with respect to prognosis than other non-immune-related post-transplant morbidities. However, little i...

    journal_title:Clinical transplantation

    pub_type: 杂志文章

    doi:10.1111/j.1399-0012.2007.00788.x

    authors: Uemura T,Ikegami T,Sanchez EQ,Jennings LW,Narasimhan G,McKenna GJ,Randall HB,Chinnakotla S,Levy MF,Goldstein RM,Klintmalm GB

    更新日期:2008-05-01 00:00:00

  • Orthotopic liver transplantation for adult-onset type II citrullinaemia.

    abstract::Citrullinaemia is a rare autosomal recessive disorder due to a deficiency of argininosuccinate synthetase (ASS). While the clinical course of the adult onset form (Type II) is unpredictable, many patients undergo sudden deterioration with progressive cerebral oedema. Two patients with Type II citrullinaemia were refer...

    journal_title:Clinical transplantation

    pub_type: 杂志文章

    doi:

    authors: Kawamoto S,Strong RW,Kerlin P,Lynch SV,Steadman C,Kobayashi K,Nakagawa S,Matsunami H,Akatsu T,Saheki T

    更新日期:1997-10-01 00:00:00

  • Intra-operative cardiac arrests during liver transplantation - a retrospective review of the first 15 yr in Asian population.

    abstract::Although many report intra-operative cardiac arrests (ICAs) in liver transplantation (LT), the incidence, major causes, and outcome remain unclear. We aimed to investigate retrospectively, the incidence, nature, and outcome of ICA in Asian population and to identify risk factors for ICA. Consecutive 1071 LTs in an ins...

    journal_title:Clinical transplantation

    pub_type: 杂志文章

    doi:10.1111/ctr.12085

    authors: Lee SH,Gwak MS,Choi SJ,Shin YH,Ko JS,Kim GS,Lee SY,Kim MH,Park HG,Lee SK,Jeon HJ

    更新日期:2013-03-01 00:00:00