Platelet 12-lipoxygenase and stem cells in Barrett's esophagus.

abstract：:Multifocal epithelial hyperplasia (MEH), also known as Heck's disease, manifests as a papulonodular lesion in the oral mucosa and has been associated with the human papillomavirus, a virus related to various precancerous diseases in the oral cavity. It has a predisposition for the female gender and for children. Altho...

journal_title：Oncology letters

authors： Bascones-Martínez A,Cok S,Bascones-Ilundáin C,Arias-Herrera S,Gomez-Font R,Bascones-Ilundáin J

更新日期：2012-02-01 00:00:00

abstract：:Hypoxic microenvironments and angiogenesis have been a focus of tumor research in previous years. The aim of the the present study was to create a hypoxic model and observe the effect of hypoxia on the expression of hypoxia inducible factor-1α (HIF-1α), insulin-like growth factor I (IGF-1) and vascular endothelial gro...

journal_title：Oncology letters

authors： Liu Q,Xu Z,Mao S,Chen W,Zeng R,Zhou S,Liu J

更新日期：2015-03-01 00:00:00

abstract：:The present study examined the expression of podocalyxin (PODX) in surgically-resected astrocytomas, associated the levels of PODX expression with the clinicopathological characteristics and survival outcomes of astrocytoma and assessed how PODX affected the viability of astrocytoma cells following the administration ...

journal_title：Oncology letters

authors： Huang T,Jin X,He L,Zhang M,Wu J,Wang Y,Fang J

更新日期：2013-11-01 00:00:00

abstract：:The present study was performed to quantify tumor neo-vessels, macrophages and fibroblasts in the tumor microenvironment of hepatocellular carcinoma (HCC) and explore the prognostic factors of HCC. The distribution of tumor neo-vessels, macrophages and fibroblasts was quantified by immunohistochemistry and inverted mi...

journal_title：Oncology letters

authors： Fang M,Yuan J,Chen M,Sun Z,Liu L,Cheng G,Ying H,Yang S,Chen M

更新日期：2018-04-01 00:00:00

abstract：:Cerebroma, a nervous system tumor located in the cranial cavity, seriously affects health and may even become life-threatening. The aim of the study was to investigate and discuss the expression levels of cluster of differentiation 44 (CD44) and Golgi protein 73 (GP73) in different types of cerebroma tissues and to st...

journal_title：Oncology letters

authors： Yuan Y,Shi L,Wang S

更新日期：2018-04-01 00:00:00

abstract：:LIM domain containing 2 (LIMD2) is a small LIM-only protein that has been demonstrated to promote tumor progression; however, the expression and function of LIMD2 in non-small cell lung cancer (NSCLC) has not previously been reported. In the present study, reverse transcription-quantitative PCR and western blot analys...

journal_title：Oncology letters

authors： Zhang F,Qin S,Xiao X,Tan Y,Hao P,Xu Y

更新日期：2019-08-01 00:00:00

abstract：:The expression of human transfer ribonucleic acid (tRNA) methyltransferase 9-like (KIAA1456) protein in lung cancer tissue and its effects on certain genes involved in the proliferation, migration and invasion of lung cancer cells were investigated. Immunohistochemistry was applied to stain lung cancer tissue and adja...

journal_title：Oncology letters

authors： Wang S,Liu X,Huang J,Zhang Y,Sang C,Li T,Yuan J

更新日期：2018-09-01 00:00:00

abstract：:The aim of the present study was to investigate the long non-coding RNA (lncRNA)-microRNA (miRNA)-mRNA regulatory network in gastric cancer (GC) using bioinformatics analysis. Two mRNA gene expression profiles, GSE79973 and GSE54129, and two miRNA expression profiles, GSE93415 and GSE78091, were downloaded from the Ge...

journal_title：Oncology letters

authors： Ma XY,Ma Y,Zhou H,Zhang HJ,Sun MJ

更新日期：2019-12-01 00:00:00

abstract：:Although it is the most widely used biomarker for prostate cancer, the use of prostate specific antigen (PSA) is controversial due to its limitations in specificity and sensitivity. The proteasome is a complex associated with cell proliferation and apoptosis, and the abnormity of these processes may lead to tumor occu...

journal_title：Oncology letters

authors： Wei X,Zeng W,Xie K,Diao P,Tang P

更新日期：2018-04-01 00:00:00

abstract：:The CDw75 epitope is an α(2,6) sialylated antigen overexpressed in colorectal cancer (CRC), where its expression correlates with the progression of the disease. The CDw75 epitope is located mainly in N-glycoproteins, whose identity remains unknown. The aim of the present study was to identify proteins with the CDw75 e...

journal_title：Oncology letters

authors： Mariño-Crespo Ó,Fernández-Briera A,Gil-Martín E

更新日期：2018-01-01 00:00:00

abstract：:The talin proteins are a key component of the extracellular matrix-integrin-cytoskeleton system, and our previous study suggested that talin2 contributes to the tumor invasion and metastasis processes regulated by the tumor microenvironment. In the present study, the specific effects of talin2 on the invasive ability ...

journal_title：Oncology letters

authors： Wen Z,Liang Y,Deng S,Zou L,Xie X,Yang J,Wu Y

更新日期：2019-06-01 00:00:00

abstract：:Retroperitoneal tumors are lesions with diverse pathological subtypes that originate from the retroperitoneal space; ~40% of these tumors are benign. Due to such lesions often surrounding and associating with vital abdominal blood vessels, a complete surgical resection is difficult. The current study presents a novel ...

journal_title：Oncology letters

authors： Wan Z,Yin T,Chen H,Li D

更新日期：2016-05-01 00:00:00

abstract：:Exosomes have gained increased research focus due to their key roles as messengers. The components of exosomes include proteins and RNAs that may be horizontally transferred between adjacent or distant cells. Hepatocellular carcinoma (HCC) is among the most malignant types of cancer worldwide, with exosomes implicated...

journal_title：Oncology letters

authors： Wang S,Chen G,Lin X,Xing X,Cai Z,Liu X,Liu J

更新日期：2017-12-01 00:00:00

abstract：:Fibroadenomas are a type of benign tumor that occur in young women below the age of 35 years old. The tumors are the second most common type of tumor after fibrocystic disease. The chance of carcinoma arising in a fibroadenoma is extremely low. To date, <130 such cases have been reported. Previous studies have reporte...

journal_title：Oncology letters

authors： Zheng H,Chen J,Wu X,Jin L,Qi C

更新日期：2015-09-01 00:00:00

abstract：:No standard therapy for pulmonary epithelioid hemangioendothelioma (PEH) has yet been established due to the rarity of the disease, the lack of clear standards for treatment and the partial-to-complete spontaneous regression. This report describes three cases of PHE manifested as bilateral intrapulmonary masses with a...

journal_title：Oncology letters

authors： Ye B,Li W,Feng J,Shi JX,Chen Y,Han BH

更新日期：2013-05-01 00:00:00

abstract：:Dendrobium candidum Wall ex Lindl. (D. candidum) is a traditional Chinese medicine widely used in Asia. The present study has showed that D. candidum exerted an anti-metastatic effect in mice injected with 26-M3.1 colon carcinoma cells. D. candidum showed the most marked tumor inhibitory rate of 64.5% at a dose of 400...

journal_title：Oncology letters

authors： Li G,Sun P,Zhou Y,Zhao X,Chen F

更新日期：2014-10-01 00:00:00

abstract：:The aim of the present study was to use imaging to retrospectively analyze the recurrent sites and patterns of spread of early cervical cancer following radical surgery. A total of 86 patients with cervical cancer (stage IB or IIA) showed postoperative pelvic recurrences and distant metastases. Based on positron emiss...

journal_title：Oncology letters

authors： Cheng S,Li Y,Zhang M,Tong T

更新日期：2018-09-01 00:00:00

abstract：:Small cell lung cancer (SCLC) is a type of lung cancer characterized by a rapid disease progression and poor prognosis. Its diagnosis is often accompanied by distant metastasis. A literature review revealed that metastases to the stomach from breast, lung and esophageal cancer are frequently reported. While SCLC is a ...

journal_title：Oncology letters

authors： Peng Y,Liu Q,Wang Y,Song A,Duan H,Qiu Y,Li Q,Cui HJ

更新日期：2019-08-01 00:00:00

abstract：:The aim of the present study was to identify the differentially expressed microRNAs (DEMs) between Lynch syndrome (LS) and the normal colonic (N-C) control samples, predict the target genes (TGs) and analyze the potential functions of the DEMs and TGs. The miRNA expression dataset GSE30454, which included data of 13 L...

journal_title：Oncology letters

authors： Zhou C,Li J,Li J,Wan Y,Li T,Ma P,Wang Y,Sang H

更新日期：2016-09-01 00:00:00

abstract：:The aim of the present study was to evaluate the clinical value of magnetic resonance imaging (MRI) in the preoperative T staging of gastric cancer and in the postoperative pathological diagnosis. In total, 30 patients with gastric cancer were investigated, including 19 males and 11 females (age, 50-69 years; mean age...

journal_title：Oncology letters

authors： Huo X,Yuan K,Shen Y,Li M,Wang Q,Xing L,Shi G

更新日期：2014-07-01 00:00:00

abstract：:Alcohol consumption is a risk factor for the development of hepatocellular carcinoma (HCC); however, the association between alcohol and HCC remains unknown. The present study aimed to identify key genes related to alcohol-associated HCC to improve the current understanding of the pathology of this disease. Alcohol-as...

journal_title：Oncology letters

authors： Gao B,Li S,Tan Z,Ma L,Liu J

更新日期：2019-02-01 00:00:00

abstract：:5-fluorouracil (5-FU) is one of the standard chemoradiotherapy regimens for hepatocellular carcinoma (HCC) treatment. B-cell-specific Moloney murine leukemia virus insertion site 1 (Bmi-1) has been demonstrated to regulate proliferation. Additionally, Bmi-1 overexpression has been identified in HCC cell lines and corr...

journal_title：Oncology letters

authors： Wu J,Hu D,Zhang R

更新日期：2012-10-01 00:00:00

abstract：:Natural dietary components have become the subject of an increasing amount of interest due to the side effects of anticancer treatment. Pterostilbene, an analog of resveratrol, is primarily found in grapes, and has been suggested to exert antioxidant and anticancer effects in different tumor types. The present study a...

journal_title：Oncology letters

authors： Tan KT,Chen PW,Li S,Ke TM,Lin SH,Yang CC

更新日期：2019-08-01 00:00:00

abstract：:Bladder cancer is one of the most common forms of malignancies involving the urinary system and multiple risk factors have been associated with its etiology. The most common of which include cigarette smoking and various occupational or chemical exposures. It is usually diagnosed in older individuals with an average a...

journal_title：Oncology letters

authors： Khan R,Ibrahim H,Tulpule S,Iroka N

更新日期：2016-05-01 00:00:00

abstract：:The current study presents a case of primary T-cell lymphoma (PTBL), unspecified, in a 27-year-old female. The patient received chemotherapy [cyclophosphamide, epirubicin, vindesine and prednisolone (CHOP) and VP-16 plus CHOP (ECHOP)] and autologous peripheral blood stem cell transplantation, however, relapse occurred...

journal_title：Oncology letters

authors： Gao Q,Zhang X,Xiang H,Ren G,Zheng Y

更新日期：2014-01-01 00:00:00

abstract：:Endotracheal intubation (ETI) and laryngeal mask airway (LMA) in terms of hemodynamics and reaction were compared. A total of 54 general anesthesia patients were randomized into two groups with 27 cases in each group. Acceleration index (ACI), cardiac index (CI), cardiac output (CO), left cardiac work (LCW), systemic ...

journal_title：Oncology letters

authors： Song Z,Tan J,Fang J,Bian Q,Gu L

更新日期：2019-02-01 00:00:00

abstract：:Notch signaling is well-known for its role in regulating cell self-renewal and differentiation. Within the cancer research field, it has been identified that dysregulated Notch signaling is involved directly with various types of cancer. Although Notch signaling is generally considered as oncogenic, it sometimes acts ...

journal_title：Oncology letters

authors： Jia D,Underwood J,Xu Q,Xie Q

更新日期：2019-06-01 00:00:00

abstract：:Nucleobindin 2 (NUCB-2) is a multifunctional protein that contains several functional domains and is associated with a wide variety of biological processes, such as food intake and energy homeostasis. NUCB-2 has been demonstrated to be associated with worse malignant outcomes and cell migration in breast and prostate ...

journal_title：Oncology letters

authors： Tao R,Niu WB,Dou PH,Ni SB,Yu YP,Cai LC,Wang XY,Li SY,Zhang C,Luo ZG

更新日期：2020-06-01 00:00:00

abstract：:MicroRNAs (miRs) are a group of short, endogenous, non-protein-coding and single-stranded RNAs that regulate gene expression by binding to the 3'-untranslated region (3'UTR) of mRNAs, which results in their degradation or translational repression. The aim of the present study was to investigate the expression and func...

journal_title：Oncology letters

authors： Kan Q,Su Y,Yang H

更新日期：2017-12-01 00:00:00

abstract：:WNT1-inducible-signaling pathway protein-1 (WISP-1) belongs to the family of cysteine rich 61/connective tissue growth factor/nephroblastoma overexpressed matricellular proteins, which are involved in various biological processes, including cell adhesion, proliferation, differentiation, angiogenesis and carcinogenesis...

journal_title：Oncology letters

authors： Jung EK,Kim SA,Yoon TM,Lee KH,Kim HK,Lee DH,Lee JK,Chung IJ,Joo YE,Lim SC

更新日期：2017-08-01 00:00:00