Efficacy of Polytetrafluoroethylene/Polylactide-co-glycolide (PTFE/PLGA) Laminate and PTFE/PLGA Laminate Containing Slow-Releasing Thalidomide in Delayed Adjustable Strabismus Surgery in a Rabbit Model.

abstract：:The basement membrane of the crystalline lens of the diabetic rat was found to have a similar elasticity modulus at high stress to that of normal membrane. However, at low stress and extension Young's modulus of elasticity was 0.36 (Mean) +/- 0.15 (SD) X 10(6) Nm-2 and about 30 per cent lower than that of normal membr...

journal_title：Current eye research

authors： Hayes BP,Fisher RF

更新日期：1981-01-01 00:00:00

abstract：PURPOSE:To analyze the effect of diamidines (hexamidine-diisethionat (HD), propamidin-isethionate (PD), dibromopropamidine-diisethionat (DD)), and biguanides (polyhexamethylen biguanid (PHMB), chlorhexidine (CH)) on human corneal epithelial cell, keratocyte and endothelial cell viability, proliferation, and migration, ...

journal_title：Current eye research

authors： Shi L,Stachon T,Seitz B,Wagenpfeil S,Langenbucher A,Szentmáry N

更新日期：2018-06-01 00:00:00

abstract：:About 55% of the acyl groups of dog and human vitreous are unsaturated fatty acids. The major components are oleate (18:1, n-9) and arachidonate (20:4, n-6) with moderate amounts of linoleate (18:2, n-6) and docosahexaenoate (22:6, n-3). Palmitate (16:0) and stearate (18:0) are the major saturated fatty acids. There a...

journal_title：Current eye research

authors： Reddy TS,Birkle DL,Packer AJ,Dobard P,Bazan NG

更新日期：1986-06-01 00:00:00

abstract：PURPOSE:Statins have been shown to reduce ocular inflammation in animal models of uveitis and to prevent development of uveitis in observational studies. There have been no experimental human studies evaluating statins' efficacy and safety in uveitis. In this study, we aimed to investigate efficacy and safety of simvas...

journal_title：Current eye research

authors： Shirinsky IV,Biryukova AA,Shirinsky VS

更新日期：2017-12-01 00:00:00

abstract：:Four days after corneal inoculation of mice with herpes simplex (type 1) virus (HSV), infected trigeminal ganglion cells with and without calcitonin gene-related peptide (CGRP) antigenicity were examined by electron microscopy in sections treated with colloidal gold labeled antibodies. Cells that contain CGRP were ide...

journal_title：Current eye research

authors： LaVail JH,Meade LB,Dawson CR

更新日期：1991-01-01 00:00:00

abstract：PURPOSE:To test the ability of two commercially available hydrogen peroxide disinfection solutions, one containing a surfactant and one without, to remove lipid from various contact lens materials using in vitro radiochemical experiments. METHODS:Etafilcon A, senofilcon A and balafilcon A contact lens materials were i...

journal_title：Current eye research

authors： Lorentz H,Heynen M,Tran H,Jones L

更新日期：2012-09-01 00:00:00

abstract：PURPOSE:In the limbo-corneal epithelium the stem and early precursor epithelial cell pool is confined to the limbal rim. Among the features associated with this spatial segregation is the general paucity of connexin43 (Cx43) within the limbal basal cell population and its complete absence in resident stem cells. The li...

journal_title：Current eye research

authors： Wolosin JM,Schütte M,Zieske JD,Budak MT

更新日期：2002-06-01 00:00:00

abstract：:Endothelin-1 (ET-1) affects intraocular pressure (IOP) in rabbits. First, we studied IOP responses to the intravitreal injection of various doses of ET-1 ranging from 5 ng to 5 micrograms in unanesthetized rabbits, and observed a transient rise in IOP, from 0.5 to 2 h in duration, invariably followed by a prolonged IO...

journal_title：Current eye research

authors： Sugiyama K,Haque MS,Okada K,Taniguchi T,Kitazawa Y

更新日期：1995-06-01 00:00:00

abstract：PURPOSE:This study was carried out in order to determine the most potent and novel uveitopathogenic sites of recoverin using synthetic peptides. METHODS:Several synthetic peptides containing the recoverin sequence plus adjuvants were injected into Lewis rats, and the uveitopathogenic sequence was defined, clinically, ...

journal_title：Current eye research

authors： Ohkoshi M,Abe T,Satoh N,Nakajima A,Sakuragi S

更新日期：2001-04-01 00:00:00

abstract：PURPOSE:Endothelial cells of different vascular systems may express site-specific adhesion molecules to attract leukocyte subsets. This study describes a method to visualize and compare leukocyte-endothelial interactions in three vascular beds within the same eye in mice. METHODS:Digital in vivo fluorescence microscop...

journal_title：Current eye research

authors： Rosenbaum JT,Brischetto M,Crespo S,Bierwirth M,Oveson K,Planck SR,Becker MD

更新日期：2002-03-01 00:00:00

abstract：:Purpose: To determine the prevalence of posterior segment manifestations among consecutive patients with pathological myopia attending our University Hospital general ophthalmology clinic and their association with age, refractive error, axial length and each other. Methods: Patients diagnosed with pathological myopia...

journal_title：Current eye research

authors： Elnahry AG,Khafagy MM,Esmat SM,Mortada HA

更新日期：2019-09-01 00:00:00

abstract：PURPOSE:To study changes in the morphometric characteristics of the whole brain visual-related cortex in various stages of primary open angle glaucoma (POAG) in vivo. MATERIALS AND METHODS:Thirty POAG patients (nine early stage cases and 21 advanced-late stage cases) and 30 gender-, education-, and age-matched healthy...

journal_title：Current eye research

authors： Li C,Cai P,Shi L,Lin Y,Zhang J,Liu S,Xie B,Shi Y,Yang H,Li S,Du H,Wang J

更新日期：2012-09-01 00:00:00

abstract：:Posterior subcapsular cataracts (PSC) are associated with hereditary retinal dystrophy in the Royal College of Surgeons (RCS) rat model and with human retinitis pigmentosa. The relationship of lens and retinal pathology has never been explained. Previous studies of pink-eyed RCS rats aged 2.5 to 11 months had shown an...

journal_title：Current eye research

authors： Hess HH,Newsome DA,Knapka JJ,Westney GE

更新日期：1982-01-01 00:00:00

abstract：PURPOSE:Folic acid (FA) is an essential nutrient for normal embryonic development. FA deficiency (FAD) in maternal diet increases the risk of several defects among the progeny, especially, neural tube defects. The eye begins its development from the neural tube; however, the relationship between FAD and ocular developm...

journal_title：Current eye research

authors： Sijilmassi O,López-Alonso JM,Del Río Sevilla A,Murillo González J,Barrio Asensio MDC

更新日期：2019-04-01 00:00:00

abstract：PURPOSE:Pigmentation of the iris is caused by varying amounts of melanin pigment granula in a constant number of melanocytes in the superficial stroma. Melanin has been shown to act as antioxidant. We have now investigated lipid peroxidation in dependence on stromal pigmentation in isolated porcine irises. METHODS:The...

journal_title：Current eye research

authors： Nau-Staudt K,Nau WM,Haefliger IO,Flammer J

更新日期：2001-03-01 00:00:00

abstract：:Two anti-fibrotic agents were evaluated in vitro for potential application in trabeculectomy. The rate of collagen formation by cultured rabbit corneal fibroblasts was determined by [3H]proline uptake and hydroxylation assay. Incubation of fibroblasts, for 96 hours, with 16 mM 2,4-pyridine dicarboxylic acid (2,4-PDCA)...

journal_title：Current eye research

authors： Sharir M,Zimmerman TJ

更新日期：1993-06-01 00:00:00

abstract：PURPOSE:To determine retinal vessel diameter variations in response to neuronal activity induced by diffuse luminance flicker. METHODS:The diameter of retinal arteries and veins was measured in 9 normal subjects by computer analysis of fundus pictures taken in monochromatic light under normal conditions of illuminatio...

journal_title：Current eye research

authors： Formaz F,Riva CE,Geiser M

更新日期：1997-12-01 00:00:00

abstract：PURPOSE:We identified a novel mutation in Paired Box gene 6 (PAX6) and characterized its associated clinical features of severe ocular malformation in a Chinese family with congenital aniridia. METHODS:We studied two patients with aniridia from a Chinese family. All patients and noncarriers in this family underwent fu...

journal_title：Current eye research

authors： He Y,Pan Z,Luo F

更新日期：2012-10-01 00:00:00

abstract：:Many tissues which require vitamin A store the vitamin as long-chain fatty acyl esters of retinol. As part of a study designed to characterize vitamin A metabolism in the lacrimal gland, which transports retinol from blood to lacrimal gland fluid, extracts from lacrimal glands of rabbits and rats were analyzed by non-...

journal_title：Current eye research

authors： Ubels JL,Osgood TB,Foley KM

更新日期：1988-10-01 00:00:00

abstract：:Papavarine, cholera toxin, and isoproterenol each elevated cyclic AMP in cultured rat retinal pigment epithelium and reduced the phagocytosis of isolated rod outer segments (38-66% of controls) during a 4 hour incubation. In addition, cultured pigment epithelium was preincubated with 25 mM exogenous cyclic AMP for two...

journal_title：Current eye research

authors： Edwards RB,Flaherty PM

更新日期：1986-01-01 00:00:00

abstract：PURPOSE:Increases in matrix proteins, such as type I collagen and fibronectin, are observed with aging in the retinal pigment epithelium (RPE) basement membrane. However, little is known about altered gene expression profiles of RPE associated with increases in matrix proteins. We investigated changes in gene expressio...

journal_title：Current eye research

authors： Imai H,Honda S,Kondo N,Ishibashi K,Tsukahara Y,Negi A

更新日期：2007-10-01 00:00:00

abstract：PURPOSE:We have previously described a metabolic acidosis-induced retinopathy in the neonatal rat, similar to retinopathy of prematurity (ROP). We also have reported exacerbation of oxygen-induced retinopathy by postnatal growth retardation, produced by raising newborn rats in 'expanded' litters. In the present study, ...

journal_title：Current eye research

authors： Zhang S,Leske DA,Lanier WL,Holmes JM

更新日期：2001-02-01 00:00:00

abstract：PURPOSE:To assess the effect of aging on optical quality in a normal population. METHODS:We prospectively examined 100 normal eyes of 100 healthy volunteers (50 men, 50 women; ages, 20-69 years; mean age ± standard deviation, 44.6 ± 15.5 years). We quantitatively assessed the values of MTF cutoff frequency, Strehl rat...

journal_title：Current eye research

authors： Kamiya K,Umeda K,Kobashi H,Shimizu K,Kawamorita T,Uozato H

更新日期：2012-10-01 00:00:00

abstract：PURPOSE:NiCl(2) (15 microM) enhances the ERG b-wave amplitude of vertebrate retina, up to 1.5-fold by blocking E/R-type voltage-gated Ca(2+) channels, which is mediated by blocking the release of GABA onto ionotropic GABA-A and GABA-C receptors. In vivo, it is likely that zinc, rather than nickel ions, may be involved ...

journal_title：Current eye research

authors： Siapich SA,Wrubel H,Albanna W,Alnawaiseh M,Hescheler J,Weiergräber M,Lüke M,Schneider T

更新日期：2010-04-01 00:00:00

abstract：:Trabecular meshwork cells from an inbred strain of mice (A/J) were established in tissue culture. Within 1 hour of enucleation, tissue containing the cornea and the chamber angle was excised and placed in tissue culture. Two to five days later, three cell types grew from the explants. Two of these cell types, corneal ...

journal_title：Current eye research

authors： Begley CG,Yue BY,Hendricks RL

更新日期：1991-11-01 00:00:00

abstract：PURPOSE:To compare the clinical outcomes following Descemet's membrane endothelial keratoplasty (DMEK) with 100% air tamponade versus 10% sulfur hexafluoride (SF6) tamponade. METHODS:Retrospective analysis of 108 consecutive DMEK cases subdivided by anterior chamber tamponade with 54 eyes receiving 10% SF6 and 54 eyes...

journal_title：Current eye research

authors： Rickmann A,Szurman P,Jung S,Boden KT,Wahl S,Haus A,Boden K,Januschowski K

更新日期：2018-04-01 00:00:00

abstract：:Spontaneous ocular shedding and adrenergic induction of ocular shedding were examined in rabbits infected with ten strains of herpes simplex virus type 1 (HSV-1): McKrae, KOS, F, Rodanus, 17 Syn+, RE, E-43, SC-16, MacIntyre, and CGA-3. All ocular inoculations were with 50 microliter of HSV-1 with titers between 1-10 X...

journal_title：Current eye research

authors： Hill JM,Rayfield MA,Haruta Y

更新日期：1987-01-01 00:00:00

abstract：:We established growth curves for Propionibacterium acnes isolates recovered from eyes with chronic postoperative endophthalmitis. The growth curve plotted the average of the duplicate bacterial concentration against time. The generation time for P. acnes calculated from the growth curves was approximately 5.1 hours. T...

journal_title：Current eye research

authors： Hall GS,Pratt-Rippin K,Meisler DM,Washington JA,Roussel TJ,Miller D

更新日期：1994-06-01 00:00:00

abstract：:Vernier and grating acuity were measured in infants up to 6 months of age using a two-alternative forced-choice preferential looking technique. Vernier resolution was measured using a horizontal vernier grating. The grating was presented on half of the screen while the other half contained horizontal lines which were ...

journal_title：Current eye research

authors： Manny RE,Klein SA

更新日期：1984-03-01 00:00:00

abstract：PURPOSE:To generate toxicology profiles of individual drugs on human corneal epithelial cells (HCEC) and compare their in vitro cytotoxicity. METHODS:Monolayer cultures of HCEC were harvested from two human donor eyes. Sunitinib (0.3-10 µg/mL) and Sorafenib (0.3-100 µg/mL), diluted in culture medium (CnT-BM.1, CELLnTE...

journal_title：Current eye research

authors： Bayyoud T,Hofmann J,Spitzer M,Bartz-Schmidt KU,Yoeruek E

更新日期：2014-02-01 00:00:00