A multicenter evaluation of a new therapeutic plasma exchange procedure.

Abstract:

BACKGROUND:The AMICUS (Fenwal, Inc.) was cleared in the United States for platelet (PLT) and plasma collection in 1996 with subsequent clearances for the collection of other blood products. Although not previously used for therapeutic plasma exchange (TPE), new disposables, software, and hardware were developed to enable TPE on the AMICUS. STUDY DESIGN AND METHODS:A multicenter, randomized, nonblinded, crossover paired treatment protocol was performed. Thirty patients with orders for at least two TPE procedures were randomly assigned to the AMICUS or the COBE Spectra (TerumoBCT) for the first treatment. Each patient was crossed over to the other device using the same procedure settings from the first procedure. The primary objective compared efficiency of plasma removal (EPR) with secondary objectives of comparing PLT and hemoglobin (Hb) waste plasma content, coagulation factor and complement activation, fluid balance tracking accuracy, procedure length, and adverse events. RESULTS:The EPR for the AMICUS (81.9 ± 7.62%) was superior to that of the COBE Spectra (75.2 ± 6.29%; p = 0.00001). The AMICUS also demonstrated statistically higher fluid balance accuracy (99.84%) compared to that of the COBE Spectra (98.83%; p < 0.0001) and a statistically shorter procedure time (103.9 ± 30.8 vs. 110.5 ± 27.1 min, p < 0.001). No significant differences with regard to PLT and Hb content in the waste plasma, change in patient PLT count, or changes in markers of coagulation and complement cascade activation were seen. Frequency and severity of adverse reactions were similar. CONCLUSION:The AMICUS separator can effectively perform TPE. The AMICUS demonstrated superior plasma removal efficiency compared to the COBE Spectra with no evidence of significant differences in PLT removal, hemolysis, and coagulation or complement activation.

journal_name

Transfusion

journal_title

Transfusion

authors

Winters JL,Burgstaler EA,Gottschall JL,Balogun RA,Houghton JR,Lee WJ,Snyder EL

doi

10.1111/trf.12189

subject

Has Abstract

pub_date

2013-12-01 00:00:00

pages

3269-78

issue

12

eissn

0041-1132

issn

1537-2995

journal_volume

53

pub_type

杂志文章,多中心研究,随机对照试验
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    abstract::The anti-A response in a group B patient accidentally given 1 unit transfusion of A1 blood is described. The antibody response is characterized both with conventional agglutination techniques and with radioimmunoassay using pure group A antigens with different core saccharide structures (type 1, 2, and 4 chains) and c...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1046/j.1537-2995.1988.28588337343.x

    authors: Rydberg L,Breimer ME,Samuelsson BE

    更新日期:1988-09-01 00:00:00

  • Prospective randomized and crossover comparison of two apheresis machines for peripheral blood stem cell collection: a multicenter study.

    abstract:BACKGROUND:Improving apheresis technology may lead to an efficient and safe peripheral blood stem cell (PBSC) collection. Recently, the Spectra Optia (Optia, Terumo BCT) was introduced as an automated apheresis instrument, but comparisons with other instruments have been few. This is the first randomized multicenter an...

    journal_title:Transfusion

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1111/trf.13777

    authors: Ikeda K,Minakawa K,Muroi K,Fujiwara SI,Yamada-Fujiwara M,Fujimori Y,Tanosaki R,Ohto H,Study Group for Peripheral Blood Stem Cell Collection, Cell Therapy Committee, The Japan Society of Transfusion Medicine and Cell Therapy.

    更新日期:2016-11-01 00:00:00

  • Donor body mass index is an important factor that affects peripheral blood progenitor cell yield in healthy donors after mobilization with granulocyte-colony-stimulating factor.

    abstract:BACKGROUND:The use of hematopoietic progenitor cell (HPC) transplantation has rapidly expanded in recent years. Currently, several sources of HPCs are available for transplantation including peripheral blood HPCs (PBPCs), cord blood cells, and marrow cells. Of these, PBPC collection has become the major source of HPCs....

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/trf.12238

    authors: Chen J,Burns KM,Babic A,Carrum G,Kennedy M,Segura FJ,Garcia S,Potts S,Leveque C

    更新日期:2014-01-01 00:00:00

  • Assessing transfusion competency in junior doctors: a retrospective cohort study.

    abstract:BACKGROUND:There is scope to further improve the safety of transfusion practice within the United Kingdom. This study aims to identify the current role of junior doctors in the transfusion process and to assess their competency to appropriately prescribe blood and blood products to patients. STUDY DESIGN AND METHODS:T...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/trf.12274

    authors: Graham J,Grant-Casey J,Alston R,Baker P,Pendry K

    更新日期:2014-01-01 00:00:00

  • Blood group incidence and Escherichia coli bacterial sepsis.

    abstract::Many strains of Escherichia coli possess an antigen that reacts with naturally occurring antibodies to human red cell B antigens. The authors tested the hypothesis that the presence of naturally occurring anti-B isoagglutinins afford protection against the development of E. coli septicemia. The blood groups found in 1...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1046/j.1537-2995.1986.26687043620.x

    authors: Wittels EG,Lichtman HC

    更新日期:1986-11-01 00:00:00

  • The minimum number of cord blood units needed for Koreans is 51,000.

    abstract:BACKGROUND:The inventory size for cord blood (CB) depends on the ethnic diversity of human leukocyte antigen (HLA) and the size estimation is important for public health in each ethnicity. STUDY DESIGN AND METHODS:We estimate the CB inventory size in Koreans with stored CB units (CBUs) and patients who underwent allog...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/trf.12284

    authors: Yoon JH,Oh S,Shin S,Park JS,Roh EY,Song EY,Park MH,Han KS

    更新日期:2014-03-01 00:00:00

  • High prevalence of infectious events in thrombotic thrombocytopenic purpura and genetic relationship with toll-like receptor 9 polymorphisms: experience of the French Thrombotic Microangiopathies Reference Center.

    abstract:BACKGROUND:Infectious events have been reported as major environmental triggers of thrombotic thrombocytopenic purpura (TTP). We detail here the potential association between infections and TTP. STUDY DESIGN AND METHODS:We recruited randomly and prospectively a cohort of 280 consecutive TTP patients during a 9-year pe...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/trf.12263

    authors: Morgand M,Buffet M,Busson M,Loiseau P,Malot S,Amokrane K,Fortier C,London J,Bonmarchand G,Wynckel A,Provôt F,Poullin P,Vanhille P,Presne C,Bordessoule D,Girault S,Delmas Y,Hamidou M,Mousson C,Vigneau C,Lautrette A

    更新日期:2014-02-01 00:00:00

  • A national mapping assessment of blood collection and transfusion service facilities in Afghanistan.

    abstract:BACKGROUND:The purpose of this study was to assess functionality and resources of facilities providing blood collection and transfusion services in Afghanistan. STUDY DESIGN AND METHODS:This national cross-sectional assessment included facilities collecting or transfusing blood identified through official data sources...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/j.1537-2995.2012.03674.x

    authors: Mansoor GF,Rahmani AM,Kakar MA,Hashimy P,Abrahimi P,Scott PT,Peel SA,Rentas FJ,Todd CS

    更新日期:2013-01-01 00:00:00

  • Granulocyte-colony-stimulatory factor: a strong inhibitor of natural killer cell function.

    abstract:BACKGROUND:The human cytokine granulocyte-colony stimulatory factor (G-CSF) has found widespread application in the medical treatment of neutropenia and to mobilize hematopoietic stem cells used for transplantation. So far, the effect of G-CSF on natural killer (NK) cells has not been fully investigated. STUDY DESIGN ...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/j.1537-2995.2010.02820.x

    authors: Schlahsa L,Jaimes Y,Blasczyk R,Figueiredo C

    更新日期:2011-02-01 00:00:00

  • Transfusion of ABO-nonidentical platelets is not associated with adverse clinical outcomes in cardiovascular surgery patients.

    abstract:BACKGROUND:Current blood transfusion standards in Canada and the United States permit transfusion of ABO-nonidentical platelets when ABO-identical platelets are not available. This practice increases the availability of platelets, a component in chronic shortage in Ontario, Canada because of the 5-day shelf-life. The i...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1046/j.1537-2995.2002.00037.x

    authors: Lin Y,Callum JL,Coovadia AS,Murphy PM

    更新日期:2002-02-01 00:00:00

  • Validation of simple prediction algorithms to consistently achieve CD3+ and postselection CD34+ targets with leukapheresis.

    abstract:BACKGROUND:Cellular therapies using engineered T cells, haploidentical transplants, and autologous gene therapy are increasing. Specified CD3+ or high CD34+ doses are typically required for subsequent manufacturing, manipulation, or CD34+ selection. Simple, practical, and reliable lymphocyte and hematopoietic progenito...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/trf.15576

    authors: Yoon EJ,Zhang J,Weinberg RS,Brochstein JA,Nandi V,Sachais BS,Shi PA

    更新日期:2020-01-01 00:00:00

  • Can family or replacement blood donors become regular volunteer donors?

    abstract:BACKGROUND:In sub-Saharan Africa (SSA) confirmed viral marker prevalence between family donors (FDs) and first-time volunteer nonremunerated donors (VNRDs) is similar. In a blood service collecting 10 units/1000 inhabitants, a questionnaire examined FD donation conditions and willingness of becoming repeat VNRDs. STUD...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/trf.12216

    authors: Asenso-Mensah K,Achina G,Appiah R,Owusu-Ofori S,Allain JP

    更新日期:2014-03-01 00:00:00

  • An apparent anti-Jka reacting only in the presence of methyl esters of hydroxybenzoic acid.

    abstract::An apparent anti-Jka, reacting only in the presence of methyl esters of hydroxybenzoic acid (HBA), was detected in an individual with Jk (a+) red blood cells. The antibody was first detected when a commercial low-ionic-strength-solution preparation containing the preservative methyl paraben (a methyl ester of hydroxyb...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1046/j.1537-2995.1982.22683068617.x

    authors: Halima D,Garratty G,Bueno R

    更新日期:1982-11-01 00:00:00

  • Considerations on the use of adjunct red blood cell exchange transfusion in the treatment of severe Plasmodium falciparum malaria.

    abstract:BACKGROUND:Travelers returning to the United States from malaria-endemic areas are at increased risk of a potentially fatal infection from Plasmodium falciparum, which requires prompt and aggressive treatment. STUDY DESIGN AND METHODS:Described is a case of a 7-year-old boy who was infected by P. falciparum while in A...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/j.1537-2995.2009.02530.x

    authors: Shelat SG,Lott JP,Braga MS

    更新日期:2010-04-01 00:00:00

  • Effective storage of granulocytes collected by centrifugation leukapheresis from donors stimulated with granulocyte-colony-stimulating factor.

    abstract:BACKGROUND:Donor stimulation with granulocyte-colony-stimulating factor (G-CSF) has increased the number of neutrophils (PMNs) that can be collected for granulocyte transfusion therapy. Clinical utility, however, has been limited by the inability to store functional PMNs ex vivo. This study was conducted to determine w...

    journal_title:Transfusion

    pub_type: 临床试验,杂志文章

    doi:10.1111/j.1537-2995.2005.00636.x

    authors: Hubel K,Rodger E,Gaviria JM,Price TH,Dale DC,Liles WC

    更新日期:2005-12-01 00:00:00

  • Preparation of commercial quantities of a hyperimmune human intravenous immunoglobulin preparation against an emerging infectious disease: the example of pandemic H1N1 influenza.

    abstract:BACKGROUND:The recent H1N1 pandemic provided an opportunity to conceptually assess the possibility of rapidly providing a "hyperimmune" human immunoglobulin (H-IVIG) to an emerging infectious disease, in useful quantities with respect to public health. Commercial-scale H-IVIG production from plasma collected from donor...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/j.1537-2995.2011.03347.x

    authors: Kreil TR,Mc Vey JK,Lei LS,Camacho L,Wodal W,Kerschbaum A,Segura E,Vandamme E,Gavit P,Ehrlich HJ,Barrett PN,Baker DA

    更新日期:2012-04-01 00:00:00

  • The crossmatch. A brief historical perspective.

    abstract::First described in 1907, the crossmatch has been in a constant state of modification since that time. Major milestones in the evolution of the test include demonstration of the relative importance of red blood cell typing and of the matching test, development of rapid techniques for the test, advent of high protein, a...

    journal_title:Transfusion

    pub_type: 历史文章,杂志文章

    doi:10.1046/j.1537-2995.1981.21682085750.x

    authors: Oberman HA

    更新日期:1981-11-01 00:00:00

  • The restricted use of IGHV3 superspecies genes in anti-Rh is not limited to hyperimmunized anti-D donors.

    abstract:BACKGROUND:Antibodies produced against the D antigen make use of IGHV genes restricted to the IGHV3 superfamily. These findings are based on the IGHV gene analysis in anti-D-producing B cells from hyperimmunized donors, however, and therefore the restriction might be due to the hyperimmunization. In this study the IGHV...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/j.1537-2995.2006.01047.x

    authors: Dohmen SE,Verhagen OJ,Muit J,Ligthart PC,van der Schoot CE

    更新日期:2006-12-01 00:00:00

  • Is placental blood a reliable source for the evaluation of neonatal hemostasis at birth?

    abstract:BACKGROUND:Phlebotomy is among the main determinants of anemia of prematurity. Blood sparing policies endorsed umbilical cord blood (here called placental) as an alternative source for laboratory testing. Little is known on the suitability of placental blood to evaluate neonatal hemostasis of newborn infants. We aimed ...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/trf.15785

    authors: Raffaeli G,Tripodi A,Manzoni F,Scalambrino E,Pesenti N,Amodeo I,Cavallaro G,Villamor E,Peyvandi F,Mosca F,Ghirardello S

    更新日期:2020-05-01 00:00:00

  • Freeze-dried plasma stability under prehospital field conditions.

    abstract:BACKGROUND:This study evaluated the effect of routine, uncontrolled, Israeli field storage conditions on the stability and efficacy of Lyo-Plas N freeze-dried plasma (FDP). We evaluated clotting factors V, VIII, and XI; proteins S and C; fibrinogen; partial thromboplastin time (PTT); antithrombin III (ATIII); von Wille...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/trf.15533

    authors: Zur M,Glassberg E,Gorenbein P,Epstein E,Eisenkraft A,Misgav M,Avramovich E

    更新日期:2019-11-01 00:00:00

  • Compatibility testing without a centrifuge: the slide Polybrene method.

    abstract:BACKGROUND:A simple and rapid slide Polybrene method (SP) for pretransfusion compatibility testing is described. SP is particularly suitable for use in developing countries where, due to limited resources, centrifuges and biologic reagents may not be readily available. STUDY DESIGN AND METHODS:The original manual Poly...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/j.1537-2995.2004.00659.x

    authors: Lin M

    更新日期:2004-03-01 00:00:00

  • Further evaluation of a new standard of efficacy for stored platelets.

    abstract:BACKGROUND:The proposal to assess the viability capabilities of platelets (PLTs) collected, treated, or stored in a developmental system against "fresh" PLTs from the same subject poses several important methodologic issues pertaining to the timing and manner of the collecting and separating the fresh PLTs. This study ...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/j.1537-2995.2005.00177.x

    authors: AuBuchon JP,Herschel L,Roger J

    更新日期:2005-07-01 00:00:00

  • Addressing gaps in international blood availability and transfusion safety in low- and middle-income countries: a NHLBI workshop.

    abstract::In April 2017, a workshop sponsored by the National Heart, Lung, and Blood Institute, Division of Blood Diseases and Resources, and the Center for Translation Research and Implementation Science was held to discuss blood availability and transfusion safety in low- and middle-income countries (LMICs). The purpose of th...

    journal_title:Transfusion

    pub_type: 杂志文章,评审

    doi:10.1111/trf.14598

    authors: Custer B,Zou S,Glynn SA,Makani J,Tayou Tagny C,El Ekiaby M,Sabino EC,Choudhury N,Teo D,Nelson K,Peprah E,Price L,Engelgau MM

    更新日期:2018-05-01 00:00:00

  • Blood safety and availability: continuing challenges in China's blood banking system.

    abstract::Social and economic development, along with increased health care coverage, has caused a sharp increase in the clinical demand for blood in China. Whole blood collection has increased rapidly in the past decade but has failed to keep pace with the ever-increasing demand. Overall, the country's blood safety has been im...

    journal_title:Transfusion

    pub_type: 杂志文章,评审

    doi:10.1111/trf.12273

    authors: Shi L,Wang JX,Stevens L,Ness P,Shan H

    更新日期:2014-02-01 00:00:00

  • Creating a uniform donor medical history questionnaire.

    abstract::Blood Centers of California, Inc. (BCC) is a consortium of 19 independent blood centers that collectively draw approximately 800,000 units of whole blood each year. Over the past several years, a committee of BCC, composed primarily of medical and nursing directors at member institutions, developed a Uniform Donor Med...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1046/j.1537-2995.1991.31491213302.x

    authors: Kolins J,Silvergleid AJ

    更新日期:1991-05-01 00:00:00

  • Generation of kinins during preparation and storage of whole blood-derived platelet concentrates.

    abstract:BACKGROUND:Leukoreduction of platelet (PLT) concentrates (PCs) may be associated with hypotension in recipients, and a role for bradykinin (BK)-related peptides has been proposed for this side effect. STUDY DESIGN AND METHODS:The concentration of BK and one of its vasoactive metabolites, des-arginine(9)-BK (des-Arg(9)...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/j.1537-2995.2007.01097.x

    authors: Moreau ME,Thibault L,Désormeaux A,Chagnon M,Lemieux R,Robillard P,Marceau F,Colman RW,Lepage Y,Rivard GE,Adam A

    更新日期:2007-03-01 00:00:00

  • Acute nosocomial HCV infection detected by NAT of a regular blood donor.

    abstract:BACKGROUND:Routine HCV NAT of blood donors to detect persons in the preseroconversion phase of acute infection was introduced in Canada in October 1999. The source of virus exposure was investigated in the first, and to date only, blood donor found to be HCV NAT positive, anti-HCV negative in Canada. He was a regular d...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1046/j.1537-2995.2002.00112.x

    authors: Larke B,Hu YW,Krajden M,Scalia V,Byrne SK,Boychuk LR,Klein J

    更新日期:2002-06-01 00:00:00

  • Human red cell antigens. V. Expression of In(Lu)-related p80 antigens by recessive-type Lu(a-b-) red cells.

    abstract::The In(Lu) gene, which inhibits the expression of Lutheran blood group antigens by red cells (RBCs), also down-regulates the expression of an 80-kD glycoprotein, In(Lu)-related p80, by both RBCs and a subset of white cells. This study examined the expression of multiple-RBC p80 epitopes by autosomal and X-linked reces...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1046/j.1537-2995.1988.28588337330.x

    authors: Telen MJ,Green AM

    更新日期:1988-09-01 00:00:00

  • The influence of irradiation on stored platelets.

    abstract::Platelet concentrates intended for transfusion to immunosuppressed patients are irradiated to minimize transfusion-induced graft-versus-host disease. Because few reports describe how irradiation influences stored platelets, the authors studied whether 5000 rad of gamma irradiation, the maximum dose currently used clin...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1046/j.1537-2995.1986.26587020124.x

    authors: Moroff G,George VM,Siegl AM,Luban NL

    更新日期:1986-09-01 00:00:00

  • The prevalence of human parvovirus B19 DNA and antibodies in blood donors from four Chinese blood centers.

    abstract:BACKGROUND:Human parvovirus B19 is a common human pathogen that causes a variety of diseases with outcomes ranging from asymptomatic to severe, especially in immunocompromised patients. The B19 virus can be transmitted via blood and/or blood products and its resistance to common viral inactivation and/or removal method...

    journal_title:Transfusion

    pub_type: 杂志文章

    doi:10.1111/j.1537-2995.2011.03067.x

    authors: Ke L,He M,Li C,Liu Y,Gao L,Yao F,Li J,Bi X,Lv Y,Wang J,Hirsch ML,Li W

    更新日期:2011-09-01 00:00:00