Abstract:
:Fibronectin is an adhesive molecule that plays a crucial role in wound healing, particularly in extracellular matrix (ECM) formation and also in reepithelialisation. Fibronectin plays many different roles in the wound healing process because of the presence of specific function domains and binding sites in its structure. Fibronectin interacts with different cell types, cytokines and the ECM. The main role of fibronectin is ECM formation. First, plasma fibronectin forms a provisional fibrin-fibronectin matrix, which will later be replaced by the mature ECM-containing tissue fibronectin.
journal_name
Int Wound Jjournal_title
International wound journalauthors
Lenselink EAdoi
10.1111/iwj.12109subject
Has Abstractpub_date
2015-06-01 00:00:00pages
313-6issue
3eissn
1742-4801issn
1742-481Xjournal_volume
12pub_type
杂志文章,评审abstract::A case study reporting on the successful treatment of a patient affected by a basal cell carcinoma is submitted. Because the carcinoma had infiltrated deeply, a wide excision was necessary, including the removal of bone tissue. The deep tissue defect was treated with PROMOGRAN* Matrix, a protease-modulating matrix, to...
journal_title:International wound journal
pub_type: 杂志文章
doi:10.1111/j.1742-4801.2005.00120.x
更新日期:2005-09-01 00:00:00
abstract::A sandwich graft was applied to the debrided cortical bone layer of the tibia in the case of a 72-year-old male patient with full-thickness necrotic burn injury. The combined graft consisted of a dermal template material and autologous split thickness skin graft. After application, the graft was found totally accepted...
journal_title:International wound journal
pub_type: 杂志文章
doi:10.1111/j.1742-4801.2006.00175.x
更新日期:2006-03-01 00:00:00
abstract::The aim of the study was to evaluate the maintenance of the 30° side-lying lateral tilt position among aged care residents at the risk of developing pressure injuries when using the standard care pillow and a purpose-designed positioning device. An observational study was conducted. Participants were monitored during ...
journal_title:International wound journal
pub_type: 杂志文章
doi:10.1111/iwj.13142
更新日期:2019-10-01 00:00:00
abstract::The aim of this study was to determine the prevalence, severity, location, aetiology, treatment and healing of medical device-related pressure ulcers (PUs) in intensive care patients for up to 7 days. A prospective repeated measures study design was used. Patients in six intensive care units of two major medical centr...
journal_title:International wound journal
pub_type: 杂志文章
doi:10.1111/iwj.12026
更新日期:2014-12-01 00:00:00
abstract::For the past 20 years, super-oxidised solutions (SOSs) have been shown to be potent antimicrobials and disinfectants via oxidative damage. However, the potential toxicity of SOSs on eukaryotic cells has not been documented in vitro. This is relevant because oxygen and chlorine reactive species may possibly induce agei...
journal_title:International wound journal
pub_type: 杂志文章
doi:10.1111/j.1742-481X.2007.00331.x
更新日期:2007-09-01 00:00:00
abstract::We evaluated the efficacy and safety of a povidone-iodine (PVP-I) foam dressing (Betafoam) for donor site dressing versus a hydrocellular foam dressing (Allevyn) and petrolatum gauze. This prospective Phase 4 study was conducted between March 2016 and April 2017 at eight sites in Korea. A total of 106 consenting patie...
journal_title:International wound journal
pub_type: 杂志文章
doi:10.1111/iwj.13043
更新日期:2019-04-01 00:00:00
abstract::Little is known about the cost-benefit of soft silicone foam dressings in pressure ulcer (PU) prevention among critically ill patients in the emergency department (ED) and intensive care unit (ICU). A randomised controlled trial to assess the efficacy of soft silicone foam dressings in preventing sacral and heel PUs w...
journal_title:International wound journal
pub_type: 杂志文章,随机对照试验
doi:10.1111/iwj.12160
更新日期:2015-06-01 00:00:00
abstract::Wide and deep wound defects are a challenge to surgeons, particularly when aggressive or more radical operations are unavailable. This article introduces refined techniques, indications and the clinical experience of the application of negative pressure wound therapy (NPWT) as an easy ancillary wound dressing method f...
journal_title:International wound journal
pub_type: 杂志文章
doi:10.1111/j.1742-481X.2011.00813.x
更新日期:2011-08-01 00:00:00
abstract::Increasing evidence within the literature has identified the presence of biofilms in chronic wounds and proposed that they contribute to delayed wound healing. This research aimed to investigate the presence of biofilm in diabetic foot ulcers (DFUs) using microscopy and molecular approaches and define if these are pre...
journal_title:International wound journal
pub_type: 杂志文章
doi:10.1111/iwj.12777
更新日期:2017-12-01 00:00:00
abstract::Silver nanoparticles are gaining importance as an antimicrobial agent in wound dressings. Chitin is a biopolymer envisioned to promote rapid dermal regeneration and accelerate wound healing. This study was focused on the evaluation of chitin membranes containing silver nanoparticles for use as an antimicrobial wound d...
journal_title:International wound journal
pub_type: 杂志文章
doi:10.1111/j.1742-481X.2012.01084.x
更新日期:2014-06-01 00:00:00
abstract::Use of silicone derivative and onion extract had been reported in the prevention of hypertrophic scarring. Our experience showed the preventive use of silicone derivative plus onion extract gel on hypertrophic scars after median sternotomy. In a randomized, double blinded, placebo-controlled study, 60 patients after m...
journal_title:International wound journal
pub_type: 杂志文章,随机对照试验
doi:10.1111/j.1742-481X.2011.00898.x
更新日期:2012-08-01 00:00:00
abstract::In the present study, the age- and sex-related differences in platelet ultrastructure were investigated using transmission electron microscopy (TEM). A total of 15 healthy volunteers were grouped according to age, with 5 people in each of the following groups: young group (25-45 years), middle-aged group (46-65 years)...
journal_title:International wound journal
pub_type: 杂志文章
doi:10.1111/iwj.13214
更新日期:2019-12-01 00:00:00
abstract::Venous leg ulcers are the most common form of non-healing leg ulcers. They are subjected to treatments such as topical medications, dressings, and compression therapies. This can lead to exposure to a number of allergens with subsequent sensitisation and contact dermatitis of the regional skin. This may contribute to ...
journal_title:International wound journal
pub_type: 杂志文章,多中心研究
doi:10.1111/iwj.12905
更新日期:2018-08-01 00:00:00
abstract::The critical problem of post-burn depigmentation is the lacking normal melanocytes. Auto-skin grafting and autologous non-cultured epidermal cell suspension have been used to improve the appearance. However, a large amount of skin graft is required of donor sites in the former method, while the latter method is though...
journal_title:International wound journal
pub_type: 杂志文章
doi:10.1111/iwj.12577
更新日期:2017-02-01 00:00:00
abstract::The aim of the study was to assess the reliability of measuring the cross-sectional area of diabetic foot ulcers using Image J software. The inter- and intra-rater reliability of ulcer area measures were assessed using digital images of acetate tracings of ulcers of the foot affecting 31 participants in an off-loading...
journal_title:International wound journal
pub_type: 杂志文章,随机对照试验
doi:10.1111/iwj.12769
更新日期:2017-12-01 00:00:00
abstract::Continuous delivery of oxygen therapy has been observed to improve healing for individuals with an advanced diabetic foot ulcer (DFU). However, this intervention requires the purchasing of an oxygen delivery device and moist dressings. It is unknown whether this upfront financial investment represents good value for m...
journal_title:International wound journal
pub_type: 杂志文章
doi:10.1111/iwj.13468
更新日期:2020-12-01 00:00:00
abstract::The purpose of this analysis was to evaluate the use of DermaPure, a decellularised human skin allograft, in the treatment of a variety of challenging wounds. This retrospective observational analysis reviewed a total of 37 patients from 29 different wound clinics across the USA. Each patient received one application ...
journal_title:International wound journal
pub_type: 杂志文章
doi:10.1111/iwj.12667
更新日期:2017-08-01 00:00:00
abstract::The prognosis of stage I pressure ulcers cannot be predicted; therefore, nursing interventions for preventing their deterioration have not been clearly established. This study describes the clinical course of stage I pressure ulcers and prospectively investigates the factors related to their deterioration. Thirty-one ...
journal_title:International wound journal
pub_type: 杂志文章
doi:10.1111/j.1742-481X.2006.00267.x
更新日期:2006-12-01 00:00:00
abstract::Osteoradionecrosis is an exceptional complication after the treatment of breast carcinoma. We report here a 63-year-old woman who presented with osteoradionecrosis of the sternum 17 years after initial treatment for breast cancer. Difficulty in diagnosing the lesion and its management is discussed. ...
journal_title:International wound journal
pub_type: 杂志文章
doi:10.1111/j.1742-4801.2004.00037.x
更新日期:2004-06-01 00:00:00
abstract::The aim of this study was to retrospectively evaluate the clinical and culture-positive infection rates of open Gustilo/Anderson type II and III fractures using a protocol nanocrystalline silver wound dressing and hydrosurgical debridement. Retrospective case series through chart review on all type II and III open fra...
journal_title:International wound journal
pub_type: 杂志文章
doi:10.1111/j.1742-481X.2011.00822.x
更新日期:2012-02-01 00:00:00
abstract::Diabetic foot ulcers commonly precede diabetic foot osteomyelitis (DFO) and once the latter occurs, surgical management is often performed. The presence of osteomyelitis is an independent risk factor for the development of re-ulceration. We investigated the relationship between causative organisms in osteomyelitis and...
journal_title:International wound journal
pub_type: 杂志文章
doi:10.1111/iwj.13439
更新日期:2020-12-01 00:00:00
abstract::Wound complications following arterial surgery in the groin are relatively common and can result in significant morbidity and mortality. Vascularised muscle flaps (VMF) may be used as an adjunct to aid healing, either to manage complications or prophylactically. This series describes 46 patients who received sartorius...
journal_title:International wound journal
pub_type: 杂志文章
doi:10.1111/iwj.13449
更新日期:2020-12-01 00:00:00
abstract::Over the last decade Vacuum Assisted Closure((R)) (KCI Licensing, Inc., San Antonio, TX) has been established as an effective wound care modality for managing complex acute and chronic wounds. The therapy has been widely adopted by many institutions to treat a variety of wound types. Increasingly, the therapy is being...
journal_title:International wound journal
pub_type: 杂志文章,评审
doi:10.1111/j.1742-481X.2009.00628.x
更新日期:2009-10-01 00:00:00
abstract::In recent years, oxidative stress and free radicals have been implicated in impaired wound healing. Grape (Vitis vinifera) seed extract (GSE) possesses anti-inflammatory and antioxidant properties. The present study was undertaken to assess the potential activity of grape seed hydroalcoholic extract in wound healing i...
journal_title:International wound journal
pub_type: 杂志文章
doi:10.1111/j.1742-481X.2011.00833.x
更新日期:2011-10-01 00:00:00
abstract::Chemotaxis, mitogenesis, motogenesis and cytoprotection are common cellular events involved in both tumourigenesis and tissue repair, which appear amplified upon growth factors exposure. Epidermal growth factor (EGF) promotes these events in epithelial and mesenchymal cells through the binding to a specific tyrosine k...
journal_title:International wound journal
pub_type: 杂志文章,评审
doi:10.1111/j.1742-481X.2009.00622.x
更新日期:2009-10-01 00:00:00
abstract::Skin grafting is one of the most common surgical procedures in the area of non-healing wounds by which skin or a skin substitute is placed over a wound to replace and regenerate the damaged skin. Chronic leg ulcers are an important problem and a major source of expense for Western countries and for which many differen...
journal_title:International wound journal
pub_type: 杂志文章,评审
doi:10.1111/iwj.12575
更新日期:2017-02-01 00:00:00
abstract::Pressure injuries (PIs) have now become a common complication of the elderly patients. Some studies have observed that pressure injuries may increase mortality, but this area of evidence has not been evaluated and summarised. The aim of this study was to compare the mortality of patients with pressure injuries and tho...
journal_title:International wound journal
pub_type: 杂志文章,meta分析
doi:10.1111/iwj.13243
更新日期:2019-12-01 00:00:00
abstract::Venous or mixed ulcers are common and invalidating. Cutaneous transplants may be necessary if conventional treatment is ineffective. We evaluated the performance of Cellutome in promoting the healing of venous or mixed ulcers 2 months after grafting. This was a retrospective, multi-centric, descriptive study of patien...
journal_title:International wound journal
pub_type: 杂志文章,多中心研究
doi:10.1111/iwj.12966
更新日期:2018-12-01 00:00:00
abstract::The aim of the study was to compare three sampling techniques used in routine diagnostics to identify the microbiota in chronic venous leg ulcers. A total of 46 patients with persisting venous leg ulcers were included in the study. At inclusion, swab, biopsy and filter paper pad samples were collected. After 4 weeks, ...
journal_title:International wound journal
pub_type: 杂志文章
doi:10.1111/j.1742-481X.2011.00883.x
更新日期:2012-06-01 00:00:00
abstract::Chronic wounds, including diabetic foot ulcers, pressure ulcers and venous leg ulcers, represent a significant cause of morbidity in developed countries, predominantly in older patients. The aetiology of these wounds is probably multifactorial, but the role of bacteria in their pathogenesis is still unclear. Moreover,...
journal_title:International wound journal
pub_type: 杂志文章
doi:10.1111/j.1742-481X.2011.00910.x
更新日期:2012-10-01 00:00:00