Abstract:
:Use of silicone derivative and onion extract had been reported in the prevention of hypertrophic scarring. Our experience showed the preventive use of silicone derivative plus onion extract gel on hypertrophic scars after median sternotomy. In a randomized, double blinded, placebo-controlled study, 60 patients after median sternotomy incisions were separated into two groups. All patients were treated either with silicone derivative plus onion extract gel (Cybele(®) scagel) or placebo gel twice daily for a total treatment period of 12 weeks. During each visit, pain and itching scores were graded by the patients and scar characteristics were observed by surgeons using the Vancouver scar scale. Pain and itch score values from patients' who applied silicone derivative plus onion extract gel was less than another group (P < 0·05). Pigmentation was significantly different between two groups (P < 0·05) and the reduction of scores on vascularity, pliability, height in treated group was not superior to the untreated group. No adverse events were reported by any of the patients. A silicone derivative plus onion extract gel is safe and effective for the preventing the hypertrophic scarring after median sternotomy.
journal_name
Int Wound Jjournal_title
International wound journalauthors
Jenwitheesuk K,Surakunprapha P,Jenwitheesuk K,Kuptarnond C,Prathanee S,Intanoo Wdoi
10.1111/j.1742-481X.2011.00898.xsubject
Has Abstractpub_date
2012-08-01 00:00:00pages
397-402issue
4eissn
1742-4801issn
1742-481Xjournal_volume
9pub_type
杂志文章,随机对照试验abstract::Covering the reconstructed area with a healthy soft-tissue envelope is a major challenge after limb-sparing surgery in patients with malignant bone and soft-tissue tumours. Negative pressure wound therapy (NPWT) of open wounds hastens healing and minimises the requirement for complex reconstructive soft-tissue surgery...
journal_title:International wound journal
pub_type: 杂志文章
doi:10.1111/iwj.12318
更新日期:2016-06-01 00:00:00
abstract::Wound dehiscence is a surgical complication caused by the application of opposing and distracting forces tending to pull apart the suture line. In recent years, a novel negative pressure surgical management system has been developed to prevent surgical wound complications. This system creates a closed environment that...
journal_title:International wound journal
pub_type: 杂志文章
doi:10.1111/iwj.12040
更新日期:2015-02-01 00:00:00
abstract::The aim of this systematic review was to determine the supporting evidence for the clinical use of hydrogel dressings as a first aid measure for burn wound management in the pre-hospital setting. Two authors searched three databases (Ovid Medline, Ovid Embase and The Cochrane Library) for relevant English language art...
journal_title:International wound journal
pub_type: 杂志文章,评审
doi:10.1111/iwj.12469
更新日期:2016-08-01 00:00:00
abstract::The aim of this study was to investigate the relationship between perioperative corticosteroids administration and the incidence of pressure ulcers (PUs) in cardiovascular surgical patients. A retrospective analysis was performed on data from consecutive patients who had cardiac surgery in 2012. Univariate and multiva...
journal_title:International wound journal
pub_type: 杂志文章
doi:10.1111/iwj.12168
更新日期:2015-10-01 00:00:00
abstract::Management of small-bowel fistulas which are in an open abdomen and have no soft tissue overlay or a fistula tract involves many complications and challenges. Controlling the local leakage of enteric contents has a central role in the success of medical treatment. There are several methods to deal with fistula dischar...
journal_title:International wound journal
pub_type: 杂志文章
doi:10.1111/iwj.12726
更新日期:2017-12-01 00:00:00
abstract::The aim of this study was to determine the prevalence, severity, location, aetiology, treatment and healing of medical device-related pressure ulcers (PUs) in intensive care patients for up to 7 days. A prospective repeated measures study design was used. Patients in six intensive care units of two major medical centr...
journal_title:International wound journal
pub_type: 杂志文章
doi:10.1111/iwj.12026
更新日期:2014-12-01 00:00:00
abstract::A 6-month-old Caucasian baby is described with a postaxial polydactyly of the letf foot. Radiographic examination revealed the accessory digit was composed of soft tissue, some with a tiny osseous element, originated from around the metatarsophalangeal joint, defined by floating type (FT). The parents had consistent d...
journal_title:International wound journal
pub_type: 杂志文章
doi:10.1111/iwj.12700
更新日期:2017-10-01 00:00:00
abstract::This study developed a measuring instrument of pressure-injury risk assessment competence for nursing education adopting theoretical procedures based on competence structuration to support the psychometric quality. The objective of this study is testing the psychometric properties of the instrument using simulation st...
journal_title:International wound journal
pub_type: 杂志文章
doi:10.1111/iwj.13311
更新日期:2020-06-01 00:00:00
abstract::The use of a rigid disc as a barrier between the wound bed and the wound filler during negative pressure wound therapy (NPWT) has been suggested to prevent damage to exposed organs. However, it is important to determine that the effects of NPWT, such as wound contraction and fluid removal, are maintained during treatm...
journal_title:International wound journal
pub_type: 杂志文章
doi:10.1111/j.1742-481X.2011.00805.x
更新日期:2011-08-01 00:00:00
abstract::Chronic wounds represent an aberrant biochemistry that creates a toxic proteolytic milieu which can be detrimental to the healing process. Rebalancing the wound microenvironment and addressing elevated protease activity (EPA) could therefore help facilitate healing. To understand how clinicians currently diagnose and ...
journal_title:International wound journal
pub_type: 杂志文章,评审
doi:10.1111/j.1742-481X.2012.01040.x
更新日期:2013-12-01 00:00:00
abstract::The aim of the study was to evaluate the maintenance of the 30° side-lying lateral tilt position among aged care residents at the risk of developing pressure injuries when using the standard care pillow and a purpose-designed positioning device. An observational study was conducted. Participants were monitored during ...
journal_title:International wound journal
pub_type: 杂志文章
doi:10.1111/iwj.13142
更新日期:2019-10-01 00:00:00
abstract::We report a 53-year-old farmer who developed subcutaneous and cerebral masses 24 years after penetrating trauma during a tropic storm. Computed tomography scans, magnetic resonance imaging and histopathology disclosed actinomycetoma, a disease that rarely develops after trauma and is only occasionally seen with intrac...
journal_title:International wound journal
pub_type: 杂志文章
doi:10.1111/j.1742-481X.2008.00456.x
更新日期:2008-12-01 00:00:00
abstract::Nicorandil is an original vasodilatator used to control angina by decreasing cardiac preload and afterload. Since 1997, many reports of single or multiple nicorandil-induced ulcerations have been published. To date, eight cases of nicorandil-induced fistula into adjacent organs have been described. The pathogeneses of...
journal_title:International wound journal
pub_type: 杂志文章
doi:10.1111/j.1742-481X.2012.00966.x
更新日期:2013-04-01 00:00:00
abstract::We reported the efficacy of soft silicone multilayered foam dressings in preventing intraoperatively acquired pressure injuries (IAPIs) in the prone position using a Relton-Hall frame (BOSS trial). The aim of this study was to clarify the incidence and extract the risk factors for IAPIs in cases in which polyurethane ...
journal_title:International wound journal
pub_type: 杂志文章
doi:10.1111/iwj.13287
更新日期:2020-06-01 00:00:00
abstract::Acellular dermal matrices can successfully heal wounds. This study's goal was to compare clinical outcomes of a novel, open-structure human reticular acellular dermis matrix (HR-ADM) to facilitate wound closure in non-healing diabetic foot ulcers (DFUs) versus DFUs treated with standard of care (SOC). Following a 2-we...
journal_title:International wound journal
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1111/iwj.12600
更新日期:2017-04-01 00:00:00
abstract::Major sickle cell disease syndrome (SCD) is a set of potentially serious and disabling constitutional haemoglobin pathologies characterised by chronic haemolysis and vaso-occlusion phenomena. If expression takes the form of acute vaso-occlusive crisis, SCD is currently considered to be a chronic systemic pathology, pr...
journal_title:International wound journal
pub_type: 杂志文章
doi:10.1111/iwj.13115
更新日期:2019-08-01 00:00:00
abstract::Negative pressure therapy has been successfully applied to clean, closed incisions in patients at high-risk for wound complications. Using laser Doppler flowmetry, we evaluated peristernal perfusion after cardiac surgery via median sternotomy, assessing the influence of mammary artery harvesting and the impact of nega...
journal_title:International wound journal
pub_type: 杂志文章
doi:10.1111/j.1742-481X.2010.00743.x
更新日期:2011-02-01 00:00:00
abstract:BACKGROUND:This study was designed to elucidate the in vivo efficacy of epidermal growth factor (EGF) on wound healing in non diabetic and diabetic rats. METHODS:Ninety-six male Wistar-Albino rats were randomly divided into six groups. Saline-moistened gauze, pure gelatin or EGF in gelatin-microsphere dressings were u...
journal_title:International wound journal
pub_type: 杂志文章
doi:10.1111/j.1742-481X.2009.00584.x
更新日期:2009-04-01 00:00:00
abstract::Immunosuppressive therapy is increasingly being used in clinical practice and has been shown to affect wound healing to varying degrees. This article looks at the effects of the newer immunosuppressive agents on wound healing. It is shown that wound healing is impaired via different mechanisms. Some of the animal and ...
journal_title:International wound journal
pub_type: 杂志文章,评审
doi:10.1111/j.1742-481X.2012.00950.x
更新日期:2013-02-01 00:00:00
abstract::Wound bed preparation (WBP) is an integral part of the care programme for chronic wounds. The acronym TIME is used in the context of WBP and describes four barriers to healing in chronic wounds; namely, dead Tissue, Infection and inflammation, Moisture imbalance and a non-migrating Edge. Larval debridement therapy (LD...
journal_title:International wound journal
pub_type: 杂志文章,评审
doi:10.1111/iwj.12457
更新日期:2016-08-01 00:00:00
abstract::Wound healing is a complex cellular and biochemical process and can be affected by several systemic and local factors. In this study, we aimed to discuss the aetiologic factors of non-healing wounds and the management of this complicated process with current information. The medical data of the patients who were admit...
journal_title:International wound journal
pub_type: 杂志文章
doi:10.1111/iwj.13292
更新日期:2020-04-01 00:00:00
abstract::We examined whether outcomes of care (amputation and hospitalisation) among patients with diabetes and foot ulcer differ between those who received pre-ulcer care from podiatrists and those who did not. Adult patients with diabetes and a diagnosis of a diabetic foot ulcer were found in the MarketScan Databases, 2005-2...
journal_title:International wound journal
pub_type: 杂志文章
doi:10.1111/iwj.12021
更新日期:2014-12-01 00:00:00
abstract::The aim of this article was to investigate the effectiveness of testing cold immersion recovery responses in the diabetic foot with neuropathy using a contact thermography system based on thermochromic liquid crystals. A total of 81 subjects with no history of diabetic foot ulceration were assigned to neuropathy, non ...
journal_title:International wound journal
pub_type: 杂志文章
doi:10.1111/j.1742-481X.2008.00454.x
更新日期:2008-10-01 00:00:00
abstract::Pressure ulcers are associated with a significant economic burden that, in many cases, is recognised as being avoidable. The effectiveness of pressure relieving surfaces is well documented and acknowledged in clinical guidelines on the prevention and management of pressure ulcers. Whilst pressure relieving surfaces ar...
journal_title:International wound journal
pub_type: 杂志文章
doi:10.1111/j.1742-481X.2009.00647.x
更新日期:2010-02-01 00:00:00
abstract::Silver nanoparticles are gaining importance as an antimicrobial agent in wound dressings. Chitin is a biopolymer envisioned to promote rapid dermal regeneration and accelerate wound healing. This study was focused on the evaluation of chitin membranes containing silver nanoparticles for use as an antimicrobial wound d...
journal_title:International wound journal
pub_type: 杂志文章
doi:10.1111/j.1742-481X.2012.01084.x
更新日期:2014-06-01 00:00:00
abstract::Diabetic lower extremity wounds cause substantial burden to healthcare systems, costing tens of thousands of dollars per episode. Negative pressure wound therapy (NPWT) devices have been shown to be cost-effective at treating these wounds, but the traditional devices use bulky electrical pumps that require a durable m...
journal_title:International wound journal
pub_type: 杂志文章
doi:10.1111/j.1742-481X.2011.00775.x
更新日期:2011-04-01 00:00:00
abstract::Diabetic foot ulcers commonly precede diabetic foot osteomyelitis (DFO) and once the latter occurs, surgical management is often performed. The presence of osteomyelitis is an independent risk factor for the development of re-ulceration. We investigated the relationship between causative organisms in osteomyelitis and...
journal_title:International wound journal
pub_type: 杂志文章
doi:10.1111/iwj.13439
更新日期:2020-12-01 00:00:00
abstract::Previous studies have reported that the use of incisional negative pressure wound therapy (INPWT) might reduce the incidence of wound infections, although its mechanism remains unknown. We designed a prospective study to explore the effects of INPWT on different stages of the wound healing process. After meeting the i...
journal_title:International wound journal
pub_type: 杂志文章
doi:10.1111/iwj.13497
更新日期:2020-11-25 00:00:00
abstract::The World Health Assembly declared 2020, the International Year of the Nurse and the Midwife. Recent editorials and commentaries support the leading role of nurses and midwives as frontline caregivers emphasizing the need to invest in the nursing workforce worldwide to meet global health needs. Today nurses are also l...
journal_title:International wound journal
pub_type: 杂志文章
doi:10.1111/iwj.13492
更新日期:2020-12-01 00:00:00
abstract::Although platelet gel is considered one of the most popular tools in the treatment of chronic ulcers, current consensus on its use is not unanimous. A prospective randomised trial was carried out at the Plastic Surgery Unit of the 'Salvatore Maugeri' Foundation Hospital of Pavia (Italy). The study involved 13 patients...
journal_title:International wound journal
pub_type: 杂志文章,随机对照试验
doi:10.1111/j.1742-481X.2010.00671.x
更新日期:2010-06-01 00:00:00