Leg ulcer induced by hydroxycarbamide in sickle cell disease: What is the therapeutic impact?

abstract：:Diabetic foot ulcers commonly precede diabetic foot osteomyelitis (DFO) and once the latter occurs, surgical management is often performed. The presence of osteomyelitis is an independent risk factor for the development of re-ulceration. We investigated the relationship between causative organisms in osteomyelitis and...

journal_title：International wound journal

authors： Schmidt BM,Ye W,Zhou S

更新日期：2020-12-01 00:00:00

abstract：:Subcutaneous mastectomy, the first step in sexual reassignment surgery of female-to-male transsexuals, is associated with high rates of complication and revision surgery. Also, conventional electrosurgery and the associated thermal tissue damage may compromise outcome. This retrospective randomised clinical study eval...

journal_title：International wound journal

authors： Schlosshauer T,Kiehlmann M,Riener MO,Rothenberger J,Sader R,Rieger UM

更新日期：2020-10-01 00:00:00

abstract：:Wound clinics are seeing an increase in the number of 'complex' wounds, which arise as the result of the interaction between multiple coexisting systemic pathologies, environmental factors and local wound factors. These complex wounds require an approach to diagnosis and management that can encapsulate all these facto...

journal_title：International wound journal

authors： Harding K,Gray D,Timmons J,Hurd T

更新日期：2007-06-01 00:00:00

abstract：:Pressure ulcers (PUs) are a common secondary complication experienced by community dwelling individuals with spinal cord injury (SCI). There is a paucity of literature on the health economic impact of PU in SCI population from a societal perspective. The objective of this study was to determine the resource use and co...

journal_title：International wound journal

authors： Chan BC,Nanwa N,Mittmann N,Bryant D,Coyte PC,Houghton PE

更新日期：2013-08-01 00:00:00

abstract：:Symmetrical peripheral digital gangrene is a life-changing complication, caused by a pro-thrombotic life-threatening disease, such as disseminated intravascular coagulopathy (DIC) secondary to systemic infection. We describe the unusual case of a woman who developed symmetrical peripheral digital gangrene following DI...

journal_title：International wound journal

authors： Ghafoor SZ,MacRae EA,Harding KG,Patel GK

更新日期：2010-10-01 00:00:00

abstract：:Chronic wounds represent an aberrant biochemistry that creates a toxic proteolytic milieu which can be detrimental to the healing process. Rebalancing the wound microenvironment and addressing elevated protease activity (EPA) could therefore help facilitate healing. To understand how clinicians currently diagnose and ...

journal_title：International wound journal

authors： Snyder RJ,Cullen B,Nisbet LT

更新日期：2013-12-01 00:00:00

abstract：:This literature review aimed to provide a narrative review of evidence on validity of clinical and microbial indicators of infection and to gain insights into the diagnosis of infection in chronic leg ulcers (CLUs). A search was conducted in Cinahl, Medline, the Cochrane Library databases, Embase, Web of Science, Scie...

journal_title：International wound journal

authors： Bui UT,Finlayson K,Edwards H

更新日期：2019-06-01 00:00:00

abstract：:The critical problem of post-burn depigmentation is the lacking normal melanocytes. Auto-skin grafting and autologous non-cultured epidermal cell suspension have been used to improve the appearance. However, a large amount of skin graft is required of donor sites in the former method, while the latter method is though...

journal_title：International wound journal

authors： Chen B,Xu M,Li B

更新日期：2017-02-01 00:00:00

abstract：:Iodine-based products are antibacterial. The small iodine molecular size is ideally suited to treat surface critical colonisation. Inadine is a 10% povidone iodine dressing with the equivalent of 1% available iodine that is easily extracted from the viscose backing by serum or exudate. The use of hydrophilic polyethyl...

journal_title：International wound journal

authors： Sibbald RG,Elliott JA

更新日期：2017-04-01 00:00:00

abstract：:Chronic wounds are a growing challenge for physicians and health insurance agencies. The burden of affected patients is enormous, because of pain but also because of long-lasting therapies and dependence on nursing services. In other areas of medicine, computer-based diagnostics is established, yet, accurate wound doc...

journal_title：International wound journal

authors： Stremitzer S,Wild T,Hoelzenbein T

更新日期：2007-06-01 00:00:00

abstract：:In May 2011, an international panel of wound care experts from multiple disciplines convened to develop this document to summarise the evolution of negative pressure wound therapy (NPWT) technology devices over the past 15 years, specifically concentrating on the V.A.C.(®) Therapy (KCI USA, Inc., San Antonio, TX) fam...

journal_title：International wound journal

authors： Gupta S

更新日期：2012-08-01 00:00:00

abstract：:The aim of this study was to determine the prevalence, severity, location, aetiology, treatment and healing of medical device-related pressure ulcers (PUs) in intensive care patients for up to 7 days. A prospective repeated measures study design was used. Patients in six intensive care units of two major medical centr...

journal_title：International wound journal

authors： Coyer FM,Stotts NA,Blackman VS

更新日期：2014-12-01 00:00:00

abstract：:The aim of this study was to gain a better understanding of the venous leg ulcer (VLU) management in primary health care settings located in Melbourne metropolitan and rural Victoria, Australia. We explored health professionals' perspective on the use of the Australian and New Zealand Venous Leg Ulcer Clinical Practic...

journal_title：International wound journal

authors： Weller CD,Richards C,Turnour L,Team V

更新日期：2020-06-01 00:00:00

abstract：:Facial traumatic events are commonly encountered in plastic and reconstructive surgery. Primary reconstruction is a reliable procedure with function and aesthetic considerations. We conduct a retrospective study of the experience of reconstructing facial traumatic defects in the first stage. One hundred and thirty-two...

journal_title：International wound journal

authors： Chen B,Song H,Gao Q,Xu M,Chai J

更新日期：2017-02-01 00:00:00

abstract：:The Smart Negative Pressure (SNaP) wound care system is a novel device that is single-patient use, ultra-portable, and light weight and does not rely on battery or need recharging. A systematic search was performed on major databases to identify relevant articles including case reports, retrospective case series, and ...

journal_title：International wound journal

authors： Wee IJY,Mak M,O'Donnell G,Tan J,Chong TT,Tang TY

更新日期：2019-08-01 00:00:00

abstract：:Negative pressure wound therapy (NPWT) contracts the wound and alters the pressure in the tissue of the wound edge, which accelerates wound healing. The aim of this study was to examine the effect of the type (foam or gauze) and size (small or large) of wound filler for NPWT on wound contraction and tissue pressure. N...

journal_title：International wound journal

authors： Anesäter E,Borgquist O,Hedström E,Waga J,Ingemansson R,Malmsjö M

更新日期：2011-08-01 00:00:00

abstract：:Breast cancer is a serious disease in women. We estimated the global technical success rate and complication rates of percutaneous vacuum-assisted breast biopsy (VABB). PubMed, Embase, Web of Science, and Scopus databases were retrieved up to July 2018 to find studies in which technical success rate and complication r...

journal_title：International wound journal

authors： Fang M,Liu G,Luo G,Wu T

更新日期：2019-12-01 00:00:00

abstract：:In the present study, the age- and sex-related differences in platelet ultrastructure were investigated using transmission electron microscopy (TEM). A total of 15 healthy volunteers were grouped according to age, with 5 people in each of the following groups: young group (25-45 years), middle-aged group (46-65 years)...

journal_title：International wound journal

authors： Tian J,Cheng LH,Cui X,Lei XX,Tang JB,Cheng B

更新日期：2019-12-01 00:00:00

abstract：:Previous studies have reported that the use of incisional negative pressure wound therapy (INPWT) might reduce the incidence of wound infections, although its mechanism remains unknown. We designed a prospective study to explore the effects of INPWT on different stages of the wound healing process. After meeting the i...

journal_title：International wound journal

authors： Rashed A,Csiszar M,Beledi A,Gombocz K

更新日期：2020-11-25 00:00:00

abstract：:Current embodiments of negative pressure wound therapy (NPWT) create a hermetically sealed chamber at the surface of the body using polyurethane foam connected to a vacuum pump, which is then covered by a flexible adhesive drape. Commercially available NPWT systems routinely use flexible polyethylene films that have a...

journal_title：International wound journal

authors： Daar DA,Wirth GA,Evans GR,Carmean M,Gordon IL

更新日期：2017-02-01 00:00:00

abstract：:Assess the outcome of a standardised protocol for the treatment of post-operative wound infection in patients undergoing deformity correction for neuro-muscular scoliosis (NMS). Retrospective review of 443 consecutive patients with a minimum 18 months' follow-up, following a primary posterior deformity correction for ...

journal_title：International wound journal

authors： Haleem S,Edwin J,Bashir MA,Soltani S,Nadarajah R,Kieser DC

更新日期：2020-06-01 00:00:00

abstract：:Wide and deep wound defects are a challenge to surgeons, particularly when aggressive or more radical operations are unavailable. This article introduces refined techniques, indications and the clinical experience of the application of negative pressure wound therapy (NPWT) as an easy ancillary wound dressing method f...

journal_title：International wound journal

authors： Lee DL,Ryu AY,Rhee SC

更新日期：2011-08-01 00:00:00

abstract：:Numerous comorbidities and cofactors have been known to influence wound healing processes. In this multicentre study, clinical data of 1 000 patients with chronic leg ulcers from ten specialised dermatological wound care centers were analysed. The patient cohort comprised 567 females and 433 males with an average age ...

journal_title：International wound journal

authors： Jockenhöfer F,Gollnick H,Herberger K,Isbary G,Renner R,Stücker M,Valesky E,Wollina U,Weichenthal M,Karrer S,Kuepper B,Roesch A,Dissemond J

更新日期：2016-10-01 00:00:00

abstract：:Patients with rheumatoid arthritis may develop leg ulcers of varied aetiologies, including venous disease, infection and inflammation (vasculitis or pyoderma gangrenosum). The leg ulcers in rheumatoid arthritis patients may involve several of these aetiological factors and are often difficult to heal. Both the ulcers ...

journal_title：International wound journal

authors： Coelho S,Amarelo M,Ryan S,Reddy M,Sibbald RG

更新日期：2004-04-01 00:00:00

abstract：:The use of lavage was compared to negative pressure wound therapy (NPWT) with instillation (NPWTi) to assess extent of soft tissue damage, debris removal and environmental cross-contamination susceptibility in three distinct models. Scanning electron microscopy in an ex vivo model showed increased visible tissue traum...

journal_title：International wound journal

authors： Allen D,LaBarbera LA,Bondre IL,Lessing MC,Rycerz AM,Kilpadi DV,Collins BA,Perkins J,McNulty AK

更新日期：2014-04-01 00:00:00

abstract：:Negative pressure therapy has been successfully applied to clean, closed incisions in patients at high-risk for wound complications. Using laser Doppler flowmetry, we evaluated peristernal perfusion after cardiac surgery via median sternotomy, assessing the influence of mammary artery harvesting and the impact of nega...

journal_title：International wound journal

authors： Atkins BZ,Tetterton JK,Petersen RP,Hurley K,Wolfe WG

更新日期：2011-02-01 00:00:00

abstract：:Little is known about the cost-benefit of soft silicone foam dressings in pressure ulcer (PU) prevention among critically ill patients in the emergency department (ED) and intensive care unit (ICU). A randomised controlled trial to assess the efficacy of soft silicone foam dressings in preventing sacral and heel PUs w...

journal_title：International wound journal

authors： Santamaria N,Liu W,Gerdtz M,Sage S,McCann J,Freeman A,Vassiliou T,DeVincentis S,Ng AW,Manias E,Knott J,Liew D

更新日期：2015-06-01 00:00:00

abstract：:Foreign modelling agent reactions (FMAR) are the result of the injection of unapproved high-viscosity fluids with the purpose of cosmetic body modelling. Its consequences lead to ulceration, disfigurement and even death, and it has reached epidemic proportions in several regions of the world. We describe a series of p...

journal_title：International wound journal

authors： Martínez-Villarreal AA,Asz-Sigall D,Gutiérrez-Mendoza D,Serena TE,Lozano-Platonoff A,Sanchez-Cruz LY,Toussaint-Caire S,Domínguez-Cherit J,López-García LA,Cárdenas-Sánchez A,Contreras-Ruiz J

更新日期：2017-06-01 00:00:00

abstract：:Recent studies have indicated the potential benefits of Non-thermal atmospheric pressure plasma (NTAPP) as a novel therapeutic approach. The purpose of the current study was thus to assess the effect of NTAPP on gingival wound healing. Fifteen patients with bilaterally symmetrical gingival hyperplasia were included in...

journal_title：International wound journal

authors： Kusakci-Seker B,Demirayak-Akdemir M

更新日期：2020-10-01 00:00:00

abstract：:We present a new surgical modification to allow propeller perforator flaps to cover pressure sores at various locations. We used a propeller perforator flap concept based on the detection of newly formed perforator vessels located 1 cm from the wound margin and stimulated by the chronic inflammation process. Between J...

journal_title：International wound journal

authors： Kelahmetoglu O,Van Landuyt K,Yagmur C,Sommeling CE,Keles MK,Tayfur V,Simsek T,Demirtas Y,Guneren E

更新日期：2017-12-01 00:00:00