An audit to assess the perspectives of U.S. wound care specialists regarding the importance of proteases in wound healing and wound assessment.

abstract：:Leg ulcer management is complex, time-consuming and of high socio-economic importance. Data on cost-of-illness in leg ulcer care are sparse. The objective of this study was to evaluate the cost-of-illness in leg ulcer treatment in the metropolitan area of Hamburg. About 147 institutions involved in wound care particip...

journal_title：International wound journal

authors： Augustin M,Brocatti LK,Rustenbach SJ,Schäfer I,Herberger K

更新日期：2014-06-01 00:00:00

abstract：:Numerous comorbidities and cofactors have been known to influence wound healing processes. In this multicentre study, clinical data of 1 000 patients with chronic leg ulcers from ten specialised dermatological wound care centers were analysed. The patient cohort comprised 567 females and 433 males with an average age ...

journal_title：International wound journal

authors： Jockenhöfer F,Gollnick H,Herberger K,Isbary G,Renner R,Stücker M,Valesky E,Wollina U,Weichenthal M,Karrer S,Kuepper B,Roesch A,Dissemond J

更新日期：2016-10-01 00:00:00

abstract：:Keratin proteins have been shown to play a key role in wound healing. Controlled keratin gene (KRT) expression promotes cell growth, migration and differentiation, and as an example of the importance of keratin proteins, absence of KRT17 has been shown to delay wound closure. In addition, downregulation of KRT6 and KR...

journal_title：International wound journal

authors： Batzer AT,Marsh C,Kirsner RS

更新日期：2016-02-01 00:00:00

abstract：:We examined whether outcomes of care (amputation and hospitalisation) among patients with diabetes and foot ulcer differ between those who received pre-ulcer care from podiatrists and those who did not. Adult patients with diabetes and a diagnosis of a diabetic foot ulcer were found in the MarketScan Databases, 2005-2...

journal_title：International wound journal

authors： Gibson TB,Driver VR,Wrobel JS,Christina JR,Bagalman E,DeFrancis R,Garoufalis MG,Carls GS,Gatwood J

更新日期：2014-12-01 00:00:00

abstract：:Negative pressure wound therapy (NPWT) is an established method for the faster wound healing of chronic non-healing wounds. It is also used for laparostomy wounds and healing of split skin grafts. The commercially available machine and the consumables for NPWT are very expensive and economically not feasible in develo...

journal_title：International wound journal

authors： Gopal SV,Solomon A

更新日期：2019-02-01 00:00:00

abstract：:A study conducted in an Australian home nursing service sought to ascertain whether the provision of funding for compression bandaging and medical footwear would impact on compression therapy use, wound healing and quality of life (QoL) among people with venous leg ulcers. Clients (n = 120) were randomly allocated to ...

journal_title：International wound journal

authors： Kapp S,Miller C,Elder K

更新日期：2012-10-01 00:00:00

abstract：:Over the last decade, maggot debridement therapy (MDT) has been recognized by many clinicians as a potential adjunct to conventional therapy, and many patients with non healing, chronic ulcers have been treated. Numerous case reports and case series have described the successful use of MDT in a variety of ulcers. Howe...

journal_title：International wound journal

authors： Zarchi K,Jemec GB

更新日期：2012-10-01 00:00:00

abstract：:To describe the steps needed for a successful implementation of an e-health programme (the Mobile Wound Care system) in rural Victoria, Australia and to provide recommendations for future e-health initiatives. Wound care is a major burden on the health care system. Optimal wound care was found to be impeded by issues ...

journal_title：International wound journal

authors： Khalil H,Cullen M,Chambers H,Steers N,Walker J

更新日期：2014-06-01 00:00:00

abstract：:Infiltration of surgical wounds with long-acting local anaesthetics (LA) is used to reduce postoperative incisional pain. We hypothesised that infiltration with LA interferes with wound healing in rats. Seventy-two rats were allocated into nine groups. After intraperitoneal anaesthesia, the interscapular dorsal region...

journal_title：International wound journal

authors： Abrão J,Fernandes CR,White PF,Shimano AC,Okubo R,Lima GB,Bachur JA,Garcia SB

更新日期：2014-08-01 00:00:00

abstract：:Covering the reconstructed area with a healthy soft-tissue envelope is a major challenge after limb-sparing surgery in patients with malignant bone and soft-tissue tumours. Negative pressure wound therapy (NPWT) of open wounds hastens healing and minimises the requirement for complex reconstructive soft-tissue surgery...

journal_title：International wound journal

authors： Mermerkaya U,Bekmez S,Alkan E,Ayvaz M,Tokgozoglu M

更新日期：2016-06-01 00:00:00

abstract：:Skin grafting is one of the most common surgical procedures in the area of non-healing wounds by which skin or a skin substitute is placed over a wound to replace and regenerate the damaged skin. Chronic leg ulcers are an important problem and a major source of expense for Western countries and for which many differen...

journal_title：International wound journal

authors： Serra R,Rizzuto A,Rossi A,Perri P,Barbetta A,Abdalla K,Caroleo S,Longo C,Amantea B,Sammarco G,de Franciscis S

更新日期：2017-02-01 00:00:00

abstract：:Necrobiosis lipoidica is a rare granulomatous disorder of the skin. In up to 30% of the affected patients it can lead to ulcerations, which can impair the quality of life and are also very difficult to treat. Its pathogenesis is not fully understood. Only few studies focussing on necrobiosis lipoidica can be found, bu...

journal_title：International wound journal

authors： Franklin C,Stoffels-Weindorf M,Hillen U,Dissemond J

更新日期：2015-10-01 00:00:00

abstract：BACKGROUND:This study was designed to elucidate the in vivo efficacy of epidermal growth factor (EGF) on wound healing in non diabetic and diabetic rats. METHODS:Ninety-six male Wistar-Albino rats were randomly divided into six groups. Saline-moistened gauze, pure gelatin or EGF in gelatin-microsphere dressings were u...

journal_title：International wound journal

authors： Dogan S,Demirer S,Kepenekci I,Erkek B,Kiziltay A,Hasirci N,Müftüoglu S,Nazikoglu A,Renda N,Dincer UD,Elhan A,Kuterdem E

更新日期：2009-04-01 00:00:00

abstract：:Senescent fibroblasts, which are present in chronic ulcers, are the reason for the wound becoming chronic. In this study, we introduce full-thickness micro skin grafts in the ulcer, a surgical technique known as a 'nested graft', which gave encouraging results leading to complete wound healing in all patients. The ass...

journal_title：International wound journal

authors： Gualdi G,Crotti S,Monari P,Calzavara-Pinton P,Vitali M,Baronio M,Lougaris V

更新日期：2016-12-01 00:00:00

abstract：:Even though it is estimated that at least 300 000 people in Canada may be affected by chronic oedema/lymphoedema, recognition of the seriousness of this chronic disease in health care is scarce. Lymphoedema affects up to 70% of breast and prostate cancer patients, substantially increasing their postoperative medical c...

journal_title：International wound journal

authors： Keast DH,Despatis M,Allen JO,Brassard A

更新日期：2015-06-01 00:00:00

abstract：:Nicorandil is an original vasodilatator used to control angina by decreasing cardiac preload and afterload. Since 1997, many reports of single or multiple nicorandil-induced ulcerations have been published. To date, eight cases of nicorandil-induced fistula into adjacent organs have been described. The pathogeneses of...

journal_title：International wound journal

authors： Trechot P,Petitpain N,Guy C,Pinzano A,Javot L,Schmutz JL,Marie B,Barbaud A

更新日期：2013-04-01 00:00:00

abstract：:Diabetic lower extremity wounds cause substantial burden to healthcare systems, costing tens of thousands of dollars per episode. Negative pressure wound therapy (NPWT) devices have been shown to be cost-effective at treating these wounds, but the traditional devices use bulky electrical pumps that require a durable m...

journal_title：International wound journal

authors： Hutton DW,Sheehan P

更新日期：2011-04-01 00:00:00

abstract：:Symmetrical peripheral digital gangrene is a life-changing complication, caused by a pro-thrombotic life-threatening disease, such as disseminated intravascular coagulopathy (DIC) secondary to systemic infection. We describe the unusual case of a woman who developed symmetrical peripheral digital gangrene following DI...

journal_title：International wound journal

authors： Ghafoor SZ,MacRae EA,Harding KG,Patel GK

更新日期：2010-10-01 00:00:00

abstract：:The aim of this study was to retrospectively evaluate the clinical and culture-positive infection rates of open Gustilo/Anderson type II and III fractures using a protocol nanocrystalline silver wound dressing and hydrosurgical debridement. Retrospective case series through chart review on all type II and III open fra...

journal_title：International wound journal

authors： Keen JS,Desai PP,Smith CS,Suk M

更新日期：2012-02-01 00:00:00

abstract：:For nearly two decades, Negative Pressure Wound Therapy (NPWT) has been used for temporary wound coverage as well as wound bed preparation. The addition of instillation and dwell time as an adjunct to NPWT (NPWTi-d) enables wound bed cleaning and improved wound bed granulation. Thirty patients with different types of ...

journal_title：International wound journal

authors： Diehm YF,Loew J,Will PA,Fischer S,Hundeshagen G,Ziegler B,Gazyakan E,Kneser U,Hirche C

更新日期：2020-12-01 00:00:00

abstract：:Subcutaneous mastectomy, the first step in sexual reassignment surgery of female-to-male transsexuals, is associated with high rates of complication and revision surgery. Also, conventional electrosurgery and the associated thermal tissue damage may compromise outcome. This retrospective randomised clinical study eval...

journal_title：International wound journal

authors： Schlosshauer T,Kiehlmann M,Riener MO,Rothenberger J,Sader R,Rieger UM

更新日期：2020-10-01 00:00:00

abstract：:Chemotaxis, mitogenesis, motogenesis and cytoprotection are common cellular events involved in both tumourigenesis and tissue repair, which appear amplified upon growth factors exposure. Epidermal growth factor (EGF) promotes these events in epithelial and mesenchymal cells through the binding to a specific tyrosine k...

journal_title：International wound journal

authors： Berlanga-Acosta J,Gavilondo-Cowley J,López-Saura P,González-López T,Castro-Santana MD,López-Mola E,Guillén-Nieto G,Herrera-Martinez L

更新日期：2009-10-01 00:00:00

abstract：:Deep sternal wound infection (DSWI) is a fatal complication after median sternotomy. This study was to assess the effect of vacuum-assisted closure (VAC) combined with bi-pectoral muscle advancement flap therapy on rehabilitation for the treatment of DSWI. Fifty-two patients with DSWI underwent treatment of VAC and bi...

journal_title：International wound journal

authors： Wang C,Zhang J,Liu Z

更新日期：2020-04-01 00:00:00

abstract：:Alcohol consumption, despite influencing several organic processes, has been scarcely studied regarding the risk of developing surgical wound complications after surgical breast cancer treatment. The aim of this study was to analyse the association between alcohol consumption and the development of surgical wound comp...

journal_title：International wound journal

authors： de Menezes RF,Bergmann A,Thuler LCS

更新日期：2020-12-01 00:00:00

abstract：:Prevention and treatment of bacterial colonised/infected wounds are critical. Many commercially available silver dressings claim broad-spectrum bactericidal activity over days and are indicated for serious conditions including burns and ulcers. However, there is no peer-reviewed literature available for many newer dre...

journal_title：International wound journal

authors： Cavanagh MH,Burrell RE,Nadworny PL

更新日期：2010-10-01 00:00:00

abstract：:The aim of the study was to evaluate the maintenance of the 30° side-lying lateral tilt position among aged care residents at the risk of developing pressure injuries when using the standard care pillow and a purpose-designed positioning device. An observational study was conducted. Participants were monitored during ...

journal_title：International wound journal

authors： Kapp S,Gerdtz M,Gefen A,Prematunga R,Santamaria N

更新日期：2019-10-01 00:00:00

abstract：:Vacuum-assisted closure (VAC) therapy is a sophisticated system that maintains a closed, humid, sterile and isolated environment. Wound infection is considered a relative contraindication. The objective of this study is to extend the indications for VAC therapy to include infected wounds by demonstrating its ability t...

journal_title：International wound journal

authors： Lo Torto F,Ruggiero M,Parisi P,Borab Z,Sergi M,Carlesimo B

更新日期：2017-12-01 00:00:00

abstract：:Cushing's syndrome is a condition caused by high levels of glucocorticoids, or most commonly as a result of prolonged exposure to exogenous steroids. Clinical features include diabetes, hypertension, obesity, skin atrophy, immune suppression and delayed wound healing. We report a patient with iatrogenic Cushing's synd...

journal_title：International wound journal

authors： Biswas M,Gibby O,Ivanova-Stoilova T,Harding K

更新日期：2011-02-01 00:00:00

abstract：:Marjolin's ulcer refers to malignant degeneration in a chronic wound. Although originally described in an area of burns scar, many other chronic wounds such as osteomyelitis sinus tracts, venous stasis ulcers and chronic pressure sores have the potential to undergo malignant transformation. We present an interesting c...

journal_title：International wound journal

authors： Fairbairn NG,Hamilton SA

更新日期：2011-10-01 00:00:00

abstract：:Enzymatic debridement with collagenase is a technique that is commonly used in clinical practice. This systematic review examines the effect of collagenase on all kinds of wounds, compared to an alternative therapy, on wound healing, wound bed characteristics, cost-effectiveness and the occurrence of adverse events. W...

journal_title：International wound journal

authors： Patry J,Blanchette V

更新日期：2017-12-01 00:00:00