Abstract：
:Numerous comorbidities and cofactors have been known to influence wound healing processes. In this multicentre study, clinical data of 1 000 patients with chronic leg ulcers from ten specialised dermatological wound care centers were analysed. The patient cohort comprised 567 females and 433 males with an average age of 69·9 years. The wounds persisted on average for 40·8 months and had a mean size of 43·7 cm(2) . Venous leg ulcers represented the most common entity accounting for 51·3% of all chronic wounds, followed by mixed-type ulcers in 12·9% and arterial ulcerations in 11·0% of the patients. Vasculitis was diagnosed in 4·5%, trauma in 3·2%, pyoderma gangrenosum in 2·8%, lymphoedema in 1·7%, neoplasia in 1·0% and delayed post-surgical wound healing in 0·6% of the included patients. In total, 70·5% of patients suffered from arterial hypertension, 45·2% were obese, 27·2% had non-insulin dependent diabetes, and 24·4% dyslipidaemia. Altogether 18·4% suffered from metabolic syndrome. Cofactors and comorbidities of patients with chronic leg ulcers have previously been studied but not in detail. Here, we were able to demonstrate the existence of several potentially relevant cofactors, comorbidities of their associations and geographical distributions, which should be routinely examined in patients with chronic leg ulcers and - if possible - treated.
journal_name
Int Wound Jjournal_title
International wound journalauthors
Jockenhöfer F,Gollnick H,Herberger K,Isbary G,Renner R,Stücker M,Valesky E,Wollina U,Weichenthal M,Karrer S,Kuepper B,Roesch A,Dissemond Jdoi
10.1111/iwj.12387subject
Has Abstractpub_date
2016-10-01 00:00:00pages
821-8issue
5eissn
1742-4801issn
1742-481Xjournal_volume
13pub_type
杂志文章,多中心研究abstract：:Nicorandil is an original vasodilatator used to control angina by decreasing cardiac preload and afterload. Since 1997, many reports of single or multiple nicorandil-induced ulcerations have been published. To date, eight cases of nicorandil-induced fistula into adjacent organs have been described. The pathogeneses of...
journal_title：International wound journal
pub_type： 杂志文章
doi：10.1111/j.1742-481X.2012.00966.x
更新日期：2013-04-01 00:00:00
abstract：:Breast cancer is a serious disease in women. We estimated the global technical success rate and complication rates of percutaneous vacuum-assisted breast biopsy (VABB). PubMed, Embase, Web of Science, and Scopus databases were retrieved up to July 2018 to find studies in which technical success rate and complication r...
journal_title：International wound journal
pub_type： 杂志文章,meta分析
doi：10.1111/iwj.13224
更新日期：2019-12-01 00:00:00
abstract：:Diabetic lower extremity wounds cause substantial burden to healthcare systems, costing tens of thousands of dollars per episode. Negative pressure wound therapy (NPWT) devices have been shown to be cost-effective at treating these wounds, but the traditional devices use bulky electrical pumps that require a durable m...
journal_title：International wound journal
pub_type： 杂志文章
doi：10.1111/j.1742-481X.2011.00775.x
更新日期：2011-04-01 00:00:00
abstract：:The aims of this randomised controlled study were to determine whether the application of silicone adhesive dressings with standard preventive care would reduce the impairment of skin integrity and to evaluate the subepidermal moisture (SEM) value in anatomical locations to predict impairment of skin integrity. Of the...
journal_title：International wound journal
pub_type： 杂志文章,随机对照试验
doi：10.1111/iwj.13028
更新日期：2019-03-01 00:00:00
abstract：:There are many porcine burn models that create burns using different materials (e.g. metal, water) and different burn conditions (e.g. temperature and duration of exposure). This review aims to determine whether a pooled analysis of these studies can provide insight into the burn materials and conditions required to c...
journal_title：International wound journal
pub_type： 杂志文章,评审
doi：10.1111/iwj.12786
更新日期：2017-12-01 00:00:00
abstract：:The prognosis of stage I pressure ulcers cannot be predicted; therefore, nursing interventions for preventing their deterioration have not been clearly established. This study describes the clinical course of stage I pressure ulcers and prospectively investigates the factors related to their deterioration. Thirty-one ...
journal_title：International wound journal
pub_type： 杂志文章
doi：10.1111/j.1742-481X.2006.00267.x
更新日期：2006-12-01 00:00:00
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journal_title：International wound journal
pub_type： 杂志文章
doi：10.1111/iwj.13043
更新日期：2019-04-01 00:00:00
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journal_title：International wound journal
pub_type： 杂志文章,评审
doi：10.1111/j.1742-481X.2009.00622.x
更新日期：2009-10-01 00:00:00
abstract：:Combinations of various treatment modalities were shown to be more effective than monotherapy when treating hypertrophic scars and keloids. This study was conducted to assess the effectiveness of combination therapy with non-ablative fractional laser and intralesional steroid injection. From May 2015 to June 2017, a t...
journal_title：International wound journal
pub_type： 杂志文章
doi：10.1111/iwj.13213
更新日期：2019-12-01 00:00:00
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journal_title：International wound journal
pub_type： 杂志文章
doi：10.1111/iwj.12061
更新日期：2015-04-01 00:00:00
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journal_title：International wound journal
pub_type： 杂志文章
doi：10.1111/j.1742-481X.2011.00790.x
更新日期：2011-08-01 00:00:00
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journal_title：International wound journal
pub_type： 杂志文章
doi：10.1111/j.1742-481X.2010.00662.x
更新日期：2010-04-01 00:00:00
abstract：:The World Health Assembly declared 2020, the International Year of the Nurse and the Midwife. Recent editorials and commentaries support the leading role of nurses and midwives as frontline caregivers emphasizing the need to invest in the nursing workforce worldwide to meet global health needs. Today nurses are also l...
journal_title：International wound journal
pub_type： 杂志文章
doi：10.1111/iwj.13492
更新日期：2020-12-01 00:00:00
abstract：:The aim of the study was to evaluate the maintenance of the 30° side-lying lateral tilt position among aged care residents at the risk of developing pressure injuries when using the standard care pillow and a purpose-designed positioning device. An observational study was conducted. Participants were monitored during ...
journal_title：International wound journal
pub_type： 杂志文章
doi：10.1111/iwj.13142
更新日期：2019-10-01 00:00:00
abstract：:Negative pressure wound therapy with instillation and dwell time (NPWTi-d) is an automated system used to deliver, dwell, and remove topical solutions from the wound bed. Recently, a reticulated open cell foam dressing with through holes (ROCF-CC) was developed, which assists with wound cleansing by removing thick exu...
journal_title：International wound journal
pub_type： 杂志文章
doi：10.1111/iwj.13097
更新日期：2019-06-01 00:00:00
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journal_title：International wound journal
pub_type： 杂志文章
doi：10.1111/iwj.12783
更新日期：2017-12-01 00:00:00
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journal_title：International wound journal
pub_type： 杂志文章
doi：10.1111/j.1742-481X.2008.00456.x
更新日期：2008-12-01 00:00:00
abstract：:Health care-associated infections in hospitals, including surgical site infections, contribute significantly to morbidity as well as mortality. Surgical incision management (SIM) using negative pressure wound therapy (Prevena™ Incision Management System, Kinetic Concepts, Inc., San Antonio, TX, USA) is designed to cov...
journal_title：International wound journal
pub_type： 杂志文章
doi：10.1111/iwj.12261
更新日期：2014-06-01 00:00:00
abstract：:Surgical site infections are the most common nosocomial infections in surgical patients. The preventable and the unmodifiable risk factors for deep sternal wound infections (DSWI) have been amply assessed in the literature. The aim of this review was to describe the results of the numerous published studies to describ...
journal_title：International wound journal
pub_type： 杂志文章,评审
doi：10.1111/j.1742-481X.2011.00896.x
更新日期：2012-08-01 00:00:00
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journal_title：International wound journal
pub_type： 杂志文章
doi：10.1111/iwj.13098
更新日期：2019-06-01 00:00:00
abstract：:In recent years, oxidative stress and free radicals have been implicated in impaired wound healing. Grape (Vitis vinifera) seed extract (GSE) possesses anti-inflammatory and antioxidant properties. The present study was undertaken to assess the potential activity of grape seed hydroalcoholic extract in wound healing i...
journal_title：International wound journal
pub_type： 杂志文章
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更新日期：2011-10-01 00:00:00
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journal_title：International wound journal
pub_type： 杂志文章
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更新日期：2014-12-01 00:00:00
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journal_title：International wound journal
pub_type： 杂志文章,多中心研究,随机对照试验
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更新日期：2017-04-01 00:00:00
abstract：:Foreign modelling agent reactions (FMAR) are the result of the injection of unapproved high-viscosity fluids with the purpose of cosmetic body modelling. Its consequences lead to ulceration, disfigurement and even death, and it has reached epidemic proportions in several regions of the world. We describe a series of p...
journal_title：International wound journal
pub_type： 杂志文章,评审
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更新日期：2017-06-01 00:00:00
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journal_title：International wound journal
pub_type： 杂志文章
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更新日期：2015-10-01 00:00:00
abstract：:Venous leg ulcers are the most common form of non-healing leg ulcers. They are subjected to treatments such as topical medications, dressings, and compression therapies. This can lead to exposure to a number of allergens with subsequent sensitisation and contact dermatitis of the regional skin. This may contribute to ...
journal_title：International wound journal
pub_type： 杂志文章,多中心研究
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更新日期：2018-08-01 00:00:00
abstract：:This study developed a measuring instrument of pressure-injury risk assessment competence for nursing education adopting theoretical procedures based on competence structuration to support the psychometric quality. The objective of this study is testing the psychometric properties of the instrument using simulation st...
journal_title：International wound journal
pub_type： 杂志文章
doi：10.1111/iwj.13311
更新日期：2020-06-01 00:00:00
abstract：:Chronic wounds represent an aberrant biochemistry that creates a toxic proteolytic milieu which can be detrimental to the healing process. Rebalancing the wound microenvironment and addressing elevated protease activity (EPA) could therefore help facilitate healing. To understand how clinicians currently diagnose and ...
journal_title：International wound journal
pub_type： 杂志文章,评审
doi：10.1111/j.1742-481X.2012.01040.x
更新日期：2013-12-01 00:00:00
abstract：:To describe the steps needed for a successful implementation of an e-health programme (the Mobile Wound Care system) in rural Victoria, Australia and to provide recommendations for future e-health initiatives. Wound care is a major burden on the health care system. Optimal wound care was found to be impeded by issues ...
journal_title：International wound journal
pub_type： 杂志文章
doi：10.1111/iwj.12041
更新日期：2014-06-01 00:00:00
abstract：:The Smart Negative Pressure (SNaP) wound care system is a novel device that is single-patient use, ultra-portable, and light weight and does not rely on battery or need recharging. A systematic search was performed on major databases to identify relevant articles including case reports, retrospective case series, and ...
journal_title：International wound journal
pub_type： 杂志文章
doi：10.1111/iwj.13114
更新日期：2019-08-01 00:00:00
