Evolution or revolution? Adapting to complexity in wound management.

abstract：:Pressure injuries are one of the most common and costly complications occurring in US hospitals. With up to 3 million patients affected each year, hospital-acquired pressure injuries (HAPIs) place a substantial burden on the US healthcare system. In the current study, US hospital discharge records from 9.6 million pat...

journal_title：International wound journal

authors： Wassel CL,Delhougne G,Gayle JA,Dreyfus J,Larson B

更新日期：2020-12-01 00:00:00

abstract：:This study sought to both assist in the selection of flaps for ischial pressure wound re-construction and to evaluate the overall complication rates associated with re-construction. A retrospective medical record review was conducted for 78 patients following the surgical re-construction of an ischial pressure sore. R...

journal_title：International wound journal

authors： Ahluwalia R,Martin D,Mahoney JL

更新日期：2010-04-01 00:00:00

abstract：:Mohs micrographic surgery is the best therapeutical option for hand squamous cell carcinoma without bone involvement; however, the reconstruction of the surgical defect could be very difficult if the tumour is located in the distal phalanx of a finger. We present the case of a patient with a squamous cell carcinoma of...

journal_title：International wound journal

authors： Magliano J,Rossi V,Turra N,Bazzano C

更新日期：2019-06-01 00:00:00

abstract：:The purpose of this analysis was to evaluate the use of DermaPure, a decellularised human skin allograft, in the treatment of a variety of challenging wounds. This retrospective observational analysis reviewed a total of 37 patients from 29 different wound clinics across the USA. Each patient received one application ...

journal_title：International wound journal

authors： Kimmel H,Gittleman H

更新日期：2017-08-01 00:00:00

abstract：:Venous or mixed ulcers are common and invalidating. Cutaneous transplants may be necessary if conventional treatment is ineffective. We evaluated the performance of Cellutome in promoting the healing of venous or mixed ulcers 2 months after grafting. This was a retrospective, multi-centric, descriptive study of patien...

journal_title：International wound journal

authors： Vinceneux Talvande B,Carvalho Lallement P,Safa G,Journet Tollhupp J,Lembelembe JP,Blaise S,Maillard H

更新日期：2018-12-01 00:00:00

abstract：:Digital ulcers (DUs) represent one of the major burdens for patients with systemic sclerosis (SSc), especially when associated with skin calcinosis (SC). The aim of this work is to evaluate the impact of SC in DUs of patients with SSc for clinical characteristics and prognosis assessed by the wound bed score (WBS). We...

journal_title：International wound journal

authors： Barsotti S,Venturini V,Di Battista M,Janowska A,Dini V,Della Rossa A,Mosca M

更新日期：2020-12-01 00:00:00

abstract：:The aims of this randomised controlled study were to determine whether the application of silicone adhesive dressings with standard preventive care would reduce the impairment of skin integrity and to evaluate the subepidermal moisture (SEM) value in anatomical locations to predict impairment of skin integrity. Of the...

journal_title：International wound journal

authors： Lee YJ,Kim JY,Shin WY

更新日期：2019-03-01 00:00:00

abstract：:Patients with diabetes mellitus have a lifetime risk of 15% to 25% of developing diabetic foot ulcers (DFUs). DFU is associated with significant morbidity and mortality. Wound imaging systems are useful adjuncts in monitoring of wound progress. Our study aims to review existing literature on the available wound assess...

journal_title：International wound journal

authors： Chan KS,Lo ZJ

更新日期：2020-12-01 00:00:00

abstract：:Although platelet gel is considered one of the most popular tools in the treatment of chronic ulcers, current consensus on its use is not unanimous. A prospective randomised trial was carried out at the Plastic Surgery Unit of the 'Salvatore Maugeri' Foundation Hospital of Pavia (Italy). The study involved 13 patients...

journal_title：International wound journal

authors： Scevola S,Nicoletti G,Brenta F,Isernia P,Maestri M,Faga A

更新日期：2010-06-01 00:00:00

abstract：:The aim of the study was to compare three sampling techniques used in routine diagnostics to identify the microbiota in chronic venous leg ulcers. A total of 46 patients with persisting venous leg ulcers were included in the study. At inclusion, swab, biopsy and filter paper pad samples were collected. After 4 weeks, ...

journal_title：International wound journal

authors： Gjødsbøl K,Skindersoe ME,Christensen JJ,Karlsmark T,Jørgensen B,Jensen AM,Klein BM,Sonnested MK,Krogfelt KA

更新日期：2012-06-01 00:00:00

abstract：:We present a new surgical modification to allow propeller perforator flaps to cover pressure sores at various locations. We used a propeller perforator flap concept based on the detection of newly formed perforator vessels located 1 cm from the wound margin and stimulated by the chronic inflammation process. Between J...

journal_title：International wound journal

authors： Kelahmetoglu O,Van Landuyt K,Yagmur C,Sommeling CE,Keles MK,Tayfur V,Simsek T,Demirtas Y,Guneren E

更新日期：2017-12-01 00:00:00

abstract：:Keratin proteins have been shown to play a key role in wound healing. Controlled keratin gene (KRT) expression promotes cell growth, migration and differentiation, and as an example of the importance of keratin proteins, absence of KRT17 has been shown to delay wound closure. In addition, downregulation of KRT6 and KR...

journal_title：International wound journal

authors： Batzer AT,Marsh C,Kirsner RS

更新日期：2016-02-01 00:00:00

abstract：:Health care-associated infections in hospitals, including surgical site infections, contribute significantly to morbidity as well as mortality. Surgical incision management (SIM) using negative pressure wound therapy (Prevena™ Incision Management System, Kinetic Concepts, Inc., San Antonio, TX, USA) is designed to cov...

journal_title：International wound journal

authors： Weir G

更新日期：2014-06-01 00:00:00

abstract：:The overall quality of evidence of autologous platelet-rich plasma (PRP) for treating chronic wounds remains low. While further well-designed clinical studies are clearly required to convincingly demonstrate the efficacy of autologous PRP in improved healing of venous leg ulcers (VLUs) and other chronic wounds, there ...

journal_title：International wound journal

authors： Weller CD,Gardiner EE,Arthur JF,Southey M,Andrews RK

更新日期：2019-06-01 00:00:00

abstract：:Venous leg ulcers are the most common form of non-healing leg ulcers. They are subjected to treatments such as topical medications, dressings, and compression therapies. This can lead to exposure to a number of allergens with subsequent sensitisation and contact dermatitis of the regional skin. This may contribute to ...

journal_title：International wound journal

authors： Rai R,Shenoy MM,Viswanath V,Sarma N,Majid I,Dogra S

更新日期：2018-08-01 00:00:00

abstract：:Ischaemia reperfusion (I/R) injury refers to tissue damage caused when blood supply returns to the tissue after a period of ischaemia. Matrix metalloproteinases (MMPs), neutrophil gelatinase-associated lipocalin (NGAL) and cytokines are biomarkers involved in several vascular complications. The aim of this study was t...

journal_title：International wound journal

authors： de Franciscis S,De Caridi G,Massara M,Spinelli F,Gallelli L,Buffone G,Caliò FG,Butrico L,Grande R,Serra R

更新日期：2016-10-01 00:00:00

abstract：:Cushing's syndrome is a condition caused by high levels of glucocorticoids, or most commonly as a result of prolonged exposure to exogenous steroids. Clinical features include diabetes, hypertension, obesity, skin atrophy, immune suppression and delayed wound healing. We report a patient with iatrogenic Cushing's synd...

journal_title：International wound journal

authors： Biswas M,Gibby O,Ivanova-Stoilova T,Harding K

更新日期：2011-02-01 00:00:00

abstract：:We report a 53-year-old farmer who developed subcutaneous and cerebral masses 24 years after penetrating trauma during a tropic storm. Computed tomography scans, magnetic resonance imaging and histopathology disclosed actinomycetoma, a disease that rarely develops after trauma and is only occasionally seen with intrac...

journal_title：International wound journal

authors： Verma SB,Nayak S,Pasale RK,Kittner T,Wollina U

更新日期：2008-12-01 00:00:00

abstract：:Little is known about the cost-benefit of soft silicone foam dressings in pressure ulcer (PU) prevention among critically ill patients in the emergency department (ED) and intensive care unit (ICU). A randomised controlled trial to assess the efficacy of soft silicone foam dressings in preventing sacral and heel PUs w...

journal_title：International wound journal

authors： Santamaria N,Liu W,Gerdtz M,Sage S,McCann J,Freeman A,Vassiliou T,DeVincentis S,Ng AW,Manias E,Knott J,Liew D

更新日期：2015-06-01 00:00:00

abstract：:In the present study, the age- and sex-related differences in platelet ultrastructure were investigated using transmission electron microscopy (TEM). A total of 15 healthy volunteers were grouped according to age, with 5 people in each of the following groups: young group (25-45 years), middle-aged group (46-65 years)...

journal_title：International wound journal

authors： Tian J,Cheng LH,Cui X,Lei XX,Tang JB,Cheng B

更新日期：2019-12-01 00:00:00

abstract：:Globally, wound care costs the health care system 2-3% of the total expenditure on health, which equates to several billion dollars annually. To date, there are little data on the cost and healing rates of various wounds. This has been partly because of the difficulty in tracking wound management as the majority of wo...

journal_title：International wound journal

authors： Khalil H,Cullen M,Chambers H,Carroll M,Walker J

更新日期：2016-10-01 00:00:00

abstract：:Pressure ulcers (PUs) are a common secondary complication experienced by community dwelling individuals with spinal cord injury (SCI). There is a paucity of literature on the health economic impact of PU in SCI population from a societal perspective. The objective of this study was to determine the resource use and co...

journal_title：International wound journal

authors： Chan BC,Nanwa N,Mittmann N,Bryant D,Coyte PC,Houghton PE

更新日期：2013-08-01 00:00:00

abstract：:We aimed to systematically assess the overall value of interleukin 6 (IL-6) in diagnosing neonates with sepsis. A systematic literature search was conducted using the following electronic databases: PubMed, Embase, and Cochrane, to identify eligible studies through the index words updated till November 2018. Cross-sec...

journal_title：International wound journal

authors： Sun B,Liang LF,Li J,Yang D,Zhao XB,Zhang KG

更新日期：2019-04-01 00:00:00

abstract：:This study aimed to demonstrate the antibacterial effects of bupivacaine and prilocaine on Escherichia coli, Staphylococcus aureus, and Pseudomonas aeruginosa. In our study, the in vitro antimicrobial effects of 20 mg/mL prilocaine and 5 mg/mL bupivacaine were tested against a S. aureus American-type culture collectio...

journal_title：International wound journal

authors： Kesici S,Demirci M,Kesici U

更新日期：2019-10-01 00:00:00

abstract：:This literature review aimed to provide a narrative review of evidence on validity of clinical and microbial indicators of infection and to gain insights into the diagnosis of infection in chronic leg ulcers (CLUs). A search was conducted in Cinahl, Medline, the Cochrane Library databases, Embase, Web of Science, Scie...

journal_title：International wound journal

authors： Bui UT,Finlayson K,Edwards H

更新日期：2019-06-01 00:00:00

abstract：:Infiltration of surgical wounds with long-acting local anaesthetics (LA) is used to reduce postoperative incisional pain. We hypothesised that infiltration with LA interferes with wound healing in rats. Seventy-two rats were allocated into nine groups. After intraperitoneal anaesthesia, the interscapular dorsal region...

journal_title：International wound journal

authors： Abrão J,Fernandes CR,White PF,Shimano AC,Okubo R,Lima GB,Bachur JA,Garcia SB

更新日期：2014-08-01 00:00:00

abstract：:Wound complications following arterial surgery in the groin are relatively common and can result in significant morbidity and mortality. Vascularised muscle flaps (VMF) may be used as an adjunct to aid healing, either to manage complications or prophylactically. This series describes 46 patients who received sartorius...

journal_title：International wound journal

authors： Price A,Contractor U,White R,Williams I

更新日期：2020-12-01 00:00:00

abstract：:Wound chronification and opportunistic infections stand as major factors leading to lower extremities amputations in diabetes. The molecular mechanisms underlying diabetic's torpid healing have not been elucidated. We present the case of a female diabetic patient that after a plantar abscess surgical drainage, tight g...

journal_title：International wound journal

authors： Berlanga-Acosta J,Mendoza-Mari Y,Martínez MD,Valdés-Perez C,Ojalvo AG,Armstrong DG

更新日期：2013-04-01 00:00:00

abstract：:A new method (V.A.C.ULTA Therapy System, KCI USA, Inc., San Antonio, TX) combines the benefits of negative pressure wound therapy (NPWT; V.A.C. Therapy, KCI USA, Inc.) with regulated, periodic instillation of user-selected topical wound solutions (V.A.C. VeraFlo Therapy, KCI USA, Inc.). In simulated wound model studie...

journal_title：International wound journal

authors： Rycerz AM,Allen D,Lessing MC

更新日期：2013-12-01 00:00:00

abstract：:There are many porcine burn models that create burns using different materials (e.g. metal, water) and different burn conditions (e.g. temperature and duration of exposure). This review aims to determine whether a pooled analysis of these studies can provide insight into the burn materials and conditions required to c...

journal_title：International wound journal

authors： Andrews CJ,Cuttle L

更新日期：2017-12-01 00:00:00