Autologous platelet-rich plasma for healing chronic venous leg ulcers: Clinical efficacy and potential mechanisms.

abstract：:The factors preventing healing in venous leg ulcers are still not fully understood. Iron-mediated tissue damage has been hypothesised, yet anecdotally anaemia is also thought to have a negative effect on wound healing. This article summarises the current evidence for these theories and their likely effects in the cont...

journal_title：International wound journal

authors： Ferris AE,Harding KG

更新日期：2019-12-01 00:00:00

abstract：:Immunosuppressive therapy is increasingly being used in clinical practice and has been shown to affect wound healing to varying degrees. This article looks at the effects of the newer immunosuppressive agents on wound healing. It is shown that wound healing is impaired via different mechanisms. Some of the animal and ...

journal_title：International wound journal

authors： Bootun R

更新日期：2013-02-01 00:00:00

abstract：:Gethin G, Cowman S. Case series of use of Manuka honey in leg ulceration. Abstract The historical and current literature reports the successful use of honey to manage a diversity of wound aetiologies. However, only in the last 40 years is research on its mode of action and contribution to wound healing being investiga...

journal_title：International wound journal

authors： Gethin G,Cowman S

更新日期：2005-03-01 00:00:00

abstract：:Nicorandil is an original vasodilatator used to control angina by decreasing cardiac preload and afterload. Since 1997, many reports of single or multiple nicorandil-induced ulcerations have been published. To date, eight cases of nicorandil-induced fistula into adjacent organs have been described. The pathogeneses of...

journal_title：International wound journal

authors： Trechot P,Petitpain N,Guy C,Pinzano A,Javot L,Schmutz JL,Marie B,Barbaud A

更新日期：2013-04-01 00:00:00

abstract：:Pressure injuries are key clinical indicators of care standard. In Australia, pressure injuries increase length of hospital stay by 4.31 and cost $285 million annually. This pilot study examined the effectiveness of sacral dressing in reducing the prevalence of pressure injuries in older, high-risk patients. A non ran...

journal_title：International wound journal

authors： Cubit K,McNally B,Lopez V

更新日期：2013-10-01 00:00:00

abstract：:Facial traumatic events are commonly encountered in plastic and reconstructive surgery. Primary reconstruction is a reliable procedure with function and aesthetic considerations. We conduct a retrospective study of the experience of reconstructing facial traumatic defects in the first stage. One hundred and thirty-two...

journal_title：International wound journal

authors： Chen B,Song H,Gao Q,Xu M,Chai J

更新日期：2017-02-01 00:00:00

abstract：:Increasing evidence within the literature has identified the presence of biofilms in chronic wounds and proposed that they contribute to delayed wound healing. This research aimed to investigate the presence of biofilm in diabetic foot ulcers (DFUs) using microscopy and molecular approaches and define if these are pre...

journal_title：International wound journal

authors： Johani K,Malone M,Jensen S,Gosbell I,Dickson H,Hu H,Vickery K

更新日期：2017-12-01 00:00:00

abstract：:Over the last decade, maggot debridement therapy (MDT) has been recognized by many clinicians as a potential adjunct to conventional therapy, and many patients with non healing, chronic ulcers have been treated. Numerous case reports and case series have described the successful use of MDT in a variety of ulcers. Howe...

journal_title：International wound journal

authors： Zarchi K,Jemec GB

更新日期：2012-10-01 00:00:00

abstract：:Previous studies have reported that the use of incisional negative pressure wound therapy (INPWT) might reduce the incidence of wound infections, although its mechanism remains unknown. We designed a prospective study to explore the effects of INPWT on different stages of the wound healing process. After meeting the i...

journal_title：International wound journal

authors： Rashed A,Csiszar M,Beledi A,Gombocz K

更新日期：2020-11-25 00:00:00

abstract：:Pressure ulcers are associated with a significant economic burden that, in many cases, is recognised as being avoidable. The effectiveness of pressure relieving surfaces is well documented and acknowledged in clinical guidelines on the prevention and management of pressure ulcers. Whilst pressure relieving surfaces ar...

journal_title：International wound journal

authors： Trueman P,Whitehead SJ

更新日期：2010-02-01 00:00:00

abstract：:The aim of this systematic review was to determine the supporting evidence for the clinical use of hydrogel dressings as a first aid measure for burn wound management in the pre-hospital setting. Two authors searched three databases (Ovid Medline, Ovid Embase and The Cochrane Library) for relevant English language art...

journal_title：International wound journal

authors： Goodwin NS,Spinks A,Wasiak J

更新日期：2016-08-01 00:00:00

abstract：:We aimed to systematically assess the overall value of interleukin 6 (IL-6) in diagnosing neonates with sepsis. A systematic literature search was conducted using the following electronic databases: PubMed, Embase, and Cochrane, to identify eligible studies through the index words updated till November 2018. Cross-sec...

journal_title：International wound journal

authors： Sun B,Liang LF,Li J,Yang D,Zhao XB,Zhang KG

更新日期：2019-04-01 00:00:00

abstract：:The World Health Assembly declared 2020, the International Year of the Nurse and the Midwife. Recent editorials and commentaries support the leading role of nurses and midwives as frontline caregivers emphasizing the need to invest in the nursing workforce worldwide to meet global health needs. Today nurses are also l...

journal_title：International wound journal

authors： Gethin G,Probst S,Weller C,Kottner J,Beeckman D

更新日期：2020-12-01 00:00:00

abstract：:Several researches have shown that negative-pressure wound dressings can secure split-thickness skin grafts and improve graft survival. However, in anatomically difficult body regions such as the perineum it is questionable whether these dressings have similar beneficial effects. In this study, we evaluated the effect...

journal_title：International wound journal

authors： Lee KT,Pyon JK,Lim SY,Mun GH,Oh KS,Bang SI

更新日期：2014-04-01 00:00:00

abstract：:Covering the reconstructed area with a healthy soft-tissue envelope is a major challenge after limb-sparing surgery in patients with malignant bone and soft-tissue tumours. Negative pressure wound therapy (NPWT) of open wounds hastens healing and minimises the requirement for complex reconstructive soft-tissue surgery...

journal_title：International wound journal

authors： Mermerkaya U,Bekmez S,Alkan E,Ayvaz M,Tokgozoglu M

更新日期：2016-06-01 00:00:00

abstract：:Prevention and treatment of bacterial colonised/infected wounds are critical. Many commercially available silver dressings claim broad-spectrum bactericidal activity over days and are indicated for serious conditions including burns and ulcers. However, there is no peer-reviewed literature available for many newer dre...

journal_title：International wound journal

authors： Cavanagh MH,Burrell RE,Nadworny PL

更新日期：2010-10-01 00:00:00

abstract：:Reducing and preventing postoperative pain are currently a topic of great interest. There are different modalities for providing analgesia that can provide an alternative or adjunct to opioid therapy. One mode of therapy involves the use of portable pain pump devices that can deliver continuous local anaesthesia direc...

journal_title：International wound journal

authors： Scimeca CL,Fisher TK,Bharara M,Armstrong DG

更新日期：2010-06-01 00:00:00

abstract：:This retrospective study compared the clinical outcomes of negative pressure wound therapy with reticulated open cell foam (NPWT/ROCF) as delivered by Vacuum-Assisted Therapy(®) (V.A.C.(®) Therapy, KCI Licensing Inc., San Antonio, TX) to non-NPWT/ROCF conventional therapy (CT) in split-thickness skin graft (STSG) surv...

journal_title：International wound journal

authors： Blume PA,Key JJ,Thakor P,Thakor S,Sumpio B

更新日期：2010-12-01 00:00:00

abstract：:This study developed a measuring instrument of pressure-injury risk assessment competence for nursing education adopting theoretical procedures based on competence structuration to support the psychometric quality. The objective of this study is testing the psychometric properties of the instrument using simulation st...

journal_title：International wound journal

authors： Moura ECC,Peres AM,Caliri MHL,Lopez V,F Soares S

更新日期：2020-06-01 00:00:00

abstract：:Pressure injuries are one of the most common and costly complications occurring in US hospitals. With up to 3 million patients affected each year, hospital-acquired pressure injuries (HAPIs) place a substantial burden on the US healthcare system. In the current study, US hospital discharge records from 9.6 million pat...

journal_title：International wound journal

authors： Wassel CL,Delhougne G,Gayle JA,Dreyfus J,Larson B

更新日期：2020-12-01 00:00:00

abstract：:Chronic wounds, including diabetic foot ulcers, pressure ulcers and venous leg ulcers, represent a significant cause of morbidity in developed countries, predominantly in older patients. The aetiology of these wounds is probably multifactorial, but the role of bacteria in their pathogenesis is still unclear. Moreover,...

journal_title：International wound journal

authors： Baffoni M,Bessa LJ,Grande R,Di Giulio M,Mongelli M,Ciarelli A,Cellini L

更新日期：2012-10-01 00:00:00

abstract：:Major sickle cell disease syndrome (SCD) is a set of potentially serious and disabling constitutional haemoglobin pathologies characterised by chronic haemolysis and vaso-occlusion phenomena. If expression takes the form of acute vaso-occlusive crisis, SCD is currently considered to be a chronic systemic pathology, pr...

journal_title：International wound journal

authors： Soya E,Makowski C,Blaise S

更新日期：2019-08-01 00:00:00

abstract：:Use of silicone derivative and onion extract had been reported in the prevention of hypertrophic scarring. Our experience showed the preventive use of silicone derivative plus onion extract gel on hypertrophic scars after median sternotomy. In a randomized, double blinded, placebo-controlled study, 60 patients after m...

journal_title：International wound journal

authors： Jenwitheesuk K,Surakunprapha P,Jenwitheesuk K,Kuptarnond C,Prathanee S,Intanoo W

更新日期：2012-08-01 00:00:00

abstract：:The prognosis of stage I pressure ulcers cannot be predicted; therefore, nursing interventions for preventing their deterioration have not been clearly established. This study describes the clinical course of stage I pressure ulcers and prospectively investigates the factors related to their deterioration. Thirty-one ...

journal_title：International wound journal

authors： Sato M,Sanada H,Konya C,Sugama J,Nakagami G

更新日期：2006-12-01 00:00:00

abstract：:Randomised clinical trials (RCTs) to evaluate diabetic foot wound therapies have systematically eliminated large acute wounds from evaluation, focusing only on smaller chronic wounds. The purpose of this study was to evaluate the proportion and rate of wound healing in acute and chronic wounds after partial foot amput...

journal_title：International wound journal

authors： Armstrong DG,Lavery LA,Boulton AJ

更新日期：2007-03-01 00:00:00

abstract：:Foot complications cause substantial morbidity in Tanzania, where 70% of leg amputations occur in diabetic patients. The Step by Step Foot Project was initiated to train healthcare personnel in diabetic foot management, facilitate transfer of knowledge and expertise, and improve patient education. The project comprise...

journal_title：International wound journal

authors： Abbas ZG,Lutale JK,Bakker K,Baker N,Archibald LK

更新日期：2011-04-01 00:00:00

abstract：:Surgical site infections are the most common nosocomial infections in surgical patients. The preventable and the unmodifiable risk factors for deep sternal wound infections (DSWI) have been amply assessed in the literature. The aim of this review was to describe the results of the numerous published studies to describ...

journal_title：International wound journal

authors： Buja A,Zampieron A,Cavalet S,Chiffi D,Sandonà P,Vinelli A,Baldovin T,Baldo V

更新日期：2012-08-01 00:00:00

abstract：:Bacterial colonisation and infection remain the major causes of delayed healing and graft rejection following burns. Topical treatment is necessary to reduce the incidence of burn wound infection. Silver sulphadiazine (SD-Ag) is an often used microbicidal agent. However, this treatment produces adverse reactions and s...

journal_title：International wound journal

authors： Peral MC,Martinez MA,Valdez JC

更新日期：2009-02-01 00:00:00

abstract：:Recent studies have indicated the potential benefits of Non-thermal atmospheric pressure plasma (NTAPP) as a novel therapeutic approach. The purpose of the current study was thus to assess the effect of NTAPP on gingival wound healing. Fifteen patients with bilaterally symmetrical gingival hyperplasia were included in...

journal_title：International wound journal

authors： Kusakci-Seker B,Demirayak-Akdemir M

更新日期：2020-10-01 00:00:00

abstract：:The purpose of this analysis was to evaluate the use of DermaPure, a decellularised human skin allograft, in the treatment of a variety of challenging wounds. This retrospective observational analysis reviewed a total of 37 patients from 29 different wound clinics across the USA. Each patient received one application ...

journal_title：International wound journal

authors： Kimmel H,Gittleman H

更新日期：2017-08-01 00:00:00