Abstract:
:Reducing and preventing postoperative pain are currently a topic of great interest. There are different modalities for providing analgesia that can provide an alternative or adjunct to opioid therapy. One mode of therapy involves the use of portable pain pump devices that can deliver continuous local anaesthesia directly to the site of interest. A considerable amount of attention in literature has been dedicated to using regional anaesthesia postoperatively for various surgical applications. However, to our knowledge, little or no work has been published concerning the use of infusion of regional anaesthesia in the treatment of painful lower extremity wounds. We present a case report of a 55-year-old gentleman with a complex past medical history, 2-year history of opioid dependency and a 2-week history of intractable pain associated with the combination of debilitating painful diabetic neuropathy and painful lower extremity wounds. After surgical debridement of the lower extremity wounds, substantial analgesia was achieved postoperatively through the implantation of a portable direct infusion pump device. The device supplied 2 ml/hour of 0.25% bupivacaine and resulted in a reduction in pain within the first hour of implantation. Although the device achieved maximal analgesia at 6 hours, we found that this could have been likely reduced through the use of a 5-ml bolus dose of 0.25% bupivacaine at the time of implantation. The device provided sufficient analgesia to the patient without any observed adverse effects, and showed significant potential in avoiding an increase in his requirement for other systemic analgesia including opioids.
journal_name
Int Wound Jjournal_title
International wound journalauthors
Scimeca CL,Fisher TK,Bharara M,Armstrong DGdoi
10.1111/j.1742-481X.2010.00675.xsubject
Has Abstractpub_date
2010-06-01 00:00:00pages
195-8issue
3eissn
1742-4801issn
1742-481Xpii
IWJ675journal_volume
7pub_type
杂志文章abstract::The aims of this randomised controlled study were to determine whether the application of silicone adhesive dressings with standard preventive care would reduce the impairment of skin integrity and to evaluate the subepidermal moisture (SEM) value in anatomical locations to predict impairment of skin integrity. Of the...
journal_title:International wound journal
pub_type: 杂志文章,随机对照试验
doi:10.1111/iwj.13028
更新日期:2019-03-01 00:00:00
abstract::We present a new surgical modification to allow propeller perforator flaps to cover pressure sores at various locations. We used a propeller perforator flap concept based on the detection of newly formed perforator vessels located 1 cm from the wound margin and stimulated by the chronic inflammation process. Between J...
journal_title:International wound journal
pub_type: 杂志文章
doi:10.1111/iwj.12783
更新日期:2017-12-01 00:00:00
abstract::Venous leg ulcers are the most common form of non-healing leg ulcers. They are subjected to treatments such as topical medications, dressings, and compression therapies. This can lead to exposure to a number of allergens with subsequent sensitisation and contact dermatitis of the regional skin. This may contribute to ...
journal_title:International wound journal
pub_type: 杂志文章,多中心研究
doi:10.1111/iwj.12905
更新日期:2018-08-01 00:00:00
abstract::For nearly two decades, Negative Pressure Wound Therapy (NPWT) has been used for temporary wound coverage as well as wound bed preparation. The addition of instillation and dwell time as an adjunct to NPWT (NPWTi-d) enables wound bed cleaning and improved wound bed granulation. Thirty patients with different types of ...
journal_title:International wound journal
pub_type: 杂志文章
doi:10.1111/iwj.13462
更新日期:2020-12-01 00:00:00
abstract::A study conducted in an Australian home nursing service sought to ascertain whether the provision of funding for compression bandaging and medical footwear would impact on compression therapy use, wound healing and quality of life (QoL) among people with venous leg ulcers. Clients (n = 120) were randomly allocated to ...
journal_title:International wound journal
pub_type: 杂志文章,随机对照试验
doi:10.1111/j.1742-481X.2011.00908.x
更新日期:2012-10-01 00:00:00
abstract::Nicorandil, a nicotinamide ester, was first reported to be involved in the induction of oral ulcers in 1997. Since then, many reports of single or multiple nicorandil-induced ulcerations (NIUs) have been reported. We hypothesised that in the case of high-dosage nicorandil or after an increased dosage of nicorandil, ni...
journal_title:International wound journal
pub_type: 杂志文章
doi:10.1111/iwj.12147
更新日期:2015-10-01 00:00:00
abstract::Tendinopathy is a very common disease in the general population as well as in athletes. The aim of the present study was to examine the tendon thickness and cross-sectional area (CSA) in subjects with chronic mid-portion Achilles tendinopathy (AT) who engaged in either an eccentric exercise (EE) programme with vibrati...
journal_title:International wound journal
pub_type: 杂志文章,随机对照试验
doi:10.1111/iwj.13074
更新日期:2019-04-01 00:00:00
abstract::Over the last decade Vacuum Assisted Closure((R)) (KCI Licensing, Inc., San Antonio, TX) has been established as an effective wound care modality for managing complex acute and chronic wounds. The therapy has been widely adopted by many institutions to treat a variety of wound types. Increasingly, the therapy is being...
journal_title:International wound journal
pub_type: 杂志文章,评审
doi:10.1111/j.1742-481X.2009.00628.x
更新日期:2009-10-01 00:00:00
abstract::This data review reports the results of 15 patients who were treated with Vacuum-Assisted Closure (VAC) negative pressure therapy system in addition to the timed, intermittent delivery of an instilled topical solution for management of their complex, infected wounds. Prospective data for 15 patients treated with negat...
journal_title:International wound journal
pub_type: 杂志文章
doi:10.1111/j.1742-481X.2007.00423.x
更新日期:2008-06-01 00:00:00
abstract::There are many porcine burn models that create burns using different materials (e.g. metal, water) and different burn conditions (e.g. temperature and duration of exposure). This review aims to determine whether a pooled analysis of these studies can provide insight into the burn materials and conditions required to c...
journal_title:International wound journal
pub_type: 杂志文章,评审
doi:10.1111/iwj.12786
更新日期:2017-12-01 00:00:00
abstract::The prognosis of stage I pressure ulcers cannot be predicted; therefore, nursing interventions for preventing their deterioration have not been clearly established. This study describes the clinical course of stage I pressure ulcers and prospectively investigates the factors related to their deterioration. Thirty-one ...
journal_title:International wound journal
pub_type: 杂志文章
doi:10.1111/j.1742-481X.2006.00267.x
更新日期:2006-12-01 00:00:00
abstract::Wound complications following arterial surgery in the groin are relatively common and can result in significant morbidity and mortality. Vascularised muscle flaps (VMF) may be used as an adjunct to aid healing, either to manage complications or prophylactically. This series describes 46 patients who received sartorius...
journal_title:International wound journal
pub_type: 杂志文章
doi:10.1111/iwj.13449
更新日期:2020-12-01 00:00:00
abstract::Although chronic wounds have a high socio-economic impact, data on comparative effectiveness of treatments are rare. UrgoStart(®) is a hydroactive dressing containing a nano-oligosaccharide factor (NOSF). This study aimed at evaluating the cost-effectiveness of this NOSF-containing wound dressing in vascular leg ulcer...
journal_title:International wound journal
pub_type: 杂志文章
doi:10.1111/iwj.12238
更新日期:2016-02-01 00:00:00
abstract::Randomised clinical trials (RCTs) to evaluate diabetic foot wound therapies have systematically eliminated large acute wounds from evaluation, focusing only on smaller chronic wounds. The purpose of this study was to evaluate the proportion and rate of wound healing in acute and chronic wounds after partial foot amput...
journal_title:International wound journal
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1111/j.1742-481X.2006.00270.x
更新日期:2007-03-01 00:00:00
abstract::Nicorandil is an original vasodilatator used to control angina by decreasing cardiac preload and afterload. Since 1997, many reports of single or multiple nicorandil-induced ulcerations have been published. To date, eight cases of nicorandil-induced fistula into adjacent organs have been described. The pathogeneses of...
journal_title:International wound journal
pub_type: 杂志文章
doi:10.1111/j.1742-481X.2012.00966.x
更新日期:2013-04-01 00:00:00
abstract::Previous studies have reported that the use of incisional negative pressure wound therapy (INPWT) might reduce the incidence of wound infections, although its mechanism remains unknown. We designed a prospective study to explore the effects of INPWT on different stages of the wound healing process. After meeting the i...
journal_title:International wound journal
pub_type: 杂志文章
doi:10.1111/iwj.13497
更新日期:2020-11-25 00:00:00
abstract::Chronic wounds are a significant problem in Australia. The health care-related costs of chronic wounds in Australia are considerable, equivalent to more than AUD $3.5 billion, approximately 2% of national health care expenditure. Chronic wounds can also have a significant negative impact on the health-related quality ...
journal_title:International wound journal
pub_type: 杂志文章
doi:10.1111/iwj.12996
更新日期:2019-02-01 00:00:00
abstract::Pre-tibial lacerations are complex wounds affecting a primarily aged population, with poor healing and a potentially significant impact on social well-being. Management of these wounds has changed little in 20 years, despite significant advances in wound care. A retrospective observational study was undertaken to obse...
journal_title:International wound journal
pub_type: 杂志文章,多中心研究
doi:10.1111/j.1742-481X.2011.00884.x
更新日期:2012-06-01 00:00:00
abstract::A significant proportion of chronic wounds fail to heal in response to treatment of underlying pathologies combined with good wound care practice. Current prognostic tests to identify these wounds rely on the use of algorithms based on clinically measurable parameters such as wound dimensions and wound duration. Venou...
journal_title:International wound journal
pub_type: 杂志文章,评审
doi:10.1111/j.1742-4801.2006.00212.x
更新日期:2006-06-01 00:00:00
abstract::Wound clinics are seeing an increase in the number of 'complex' wounds, which arise as the result of the interaction between multiple coexisting systemic pathologies, environmental factors and local wound factors. These complex wounds require an approach to diagnosis and management that can encapsulate all these facto...
journal_title:International wound journal
pub_type: 杂志文章,评审
doi:10.1111/j.1742-481X.2007.00329.x
更新日期:2007-06-01 00:00:00
abstract::Diabetic lower extremity wounds cause substantial burden to healthcare systems, costing tens of thousands of dollars per episode. Negative pressure wound therapy (NPWT) devices have been shown to be cost-effective at treating these wounds, but the traditional devices use bulky electrical pumps that require a durable m...
journal_title:International wound journal
pub_type: 杂志文章
doi:10.1111/j.1742-481X.2011.00775.x
更新日期:2011-04-01 00:00:00
abstract::The use of lavage was compared to negative pressure wound therapy (NPWT) with instillation (NPWTi) to assess extent of soft tissue damage, debris removal and environmental cross-contamination susceptibility in three distinct models. Scanning electron microscopy in an ex vivo model showed increased visible tissue traum...
journal_title:International wound journal
pub_type: 杂志文章
doi:10.1111/j.1742-481X.2012.01073.x
更新日期:2014-04-01 00:00:00
abstract::Leg ulcer management is complex, time-consuming and of high socio-economic importance. Data on cost-of-illness in leg ulcer care are sparse. The objective of this study was to evaluate the cost-of-illness in leg ulcer treatment in the metropolitan area of Hamburg. About 147 institutions involved in wound care particip...
journal_title:International wound journal
pub_type: 杂志文章
doi:10.1111/j.1742-481X.2012.01089.x
更新日期:2014-06-01 00:00:00
abstract::This study sought to both assist in the selection of flaps for ischial pressure wound re-construction and to evaluate the overall complication rates associated with re-construction. A retrospective medical record review was conducted for 78 patients following the surgical re-construction of an ischial pressure sore. R...
journal_title:International wound journal
pub_type: 杂志文章
doi:10.1111/j.1742-481X.2010.00662.x
更新日期:2010-04-01 00:00:00
abstract::Several researches have shown that negative-pressure wound dressings can secure split-thickness skin grafts and improve graft survival. However, in anatomically difficult body regions such as the perineum it is questionable whether these dressings have similar beneficial effects. In this study, we evaluated the effect...
journal_title:International wound journal
pub_type: 杂志文章
doi:10.1111/j.1742-481X.2012.01078.x
更新日期:2014-04-01 00:00:00
abstract::This literature review aimed to provide a narrative review of evidence on validity of clinical and microbial indicators of infection and to gain insights into the diagnosis of infection in chronic leg ulcers (CLUs). A search was conducted in Cinahl, Medline, the Cochrane Library databases, Embase, Web of Science, Scie...
journal_title:International wound journal
pub_type: 杂志文章,评审
doi:10.1111/iwj.13069
更新日期:2019-06-01 00:00:00
abstract::Patients with rheumatoid arthritis may develop leg ulcers of varied aetiologies, including venous disease, infection and inflammation (vasculitis or pyoderma gangrenosum). The leg ulcers in rheumatoid arthritis patients may involve several of these aetiological factors and are often difficult to heal. Both the ulcers ...
journal_title:International wound journal
pub_type: 杂志文章
doi:10.1111/j.1742-481x.2004.0002.x
更新日期:2004-04-01 00:00:00
abstract::This study aimed to demonstrate the antibacterial effects of bupivacaine and prilocaine on Escherichia coli, Staphylococcus aureus, and Pseudomonas aeruginosa. In our study, the in vitro antimicrobial effects of 20 mg/mL prilocaine and 5 mg/mL bupivacaine were tested against a S. aureus American-type culture collectio...
journal_title:International wound journal
pub_type: 杂志文章
doi:10.1111/iwj.13180
更新日期:2019-10-01 00:00:00
abstract::Fibronectin is an adhesive molecule that plays a crucial role in wound healing, particularly in extracellular matrix (ECM) formation and also in reepithelialisation. Fibronectin plays many different roles in the wound healing process because of the presence of specific function domains and binding sites in its structu...
journal_title:International wound journal
pub_type: 杂志文章,评审
doi:10.1111/iwj.12109
更新日期:2015-06-01 00:00:00
abstract::Use of silicone derivative and onion extract had been reported in the prevention of hypertrophic scarring. Our experience showed the preventive use of silicone derivative plus onion extract gel on hypertrophic scars after median sternotomy. In a randomized, double blinded, placebo-controlled study, 60 patients after m...
journal_title:International wound journal
pub_type: 杂志文章,随机对照试验
doi:10.1111/j.1742-481X.2011.00898.x
更新日期:2012-08-01 00:00:00