The diagnosis of infection in chronic leg ulcers: A narrative review on clinical practice.

abstract：:Skin grafting is one of the most common surgical procedures in the area of non-healing wounds by which skin or a skin substitute is placed over a wound to replace and regenerate the damaged skin. Chronic leg ulcers are an important problem and a major source of expense for Western countries and for which many differen...

journal_title：International wound journal

authors： Serra R,Rizzuto A,Rossi A,Perri P,Barbetta A,Abdalla K,Caroleo S,Longo C,Amantea B,Sammarco G,de Franciscis S

更新日期：2017-02-01 00:00:00

abstract：:Wound chronification and opportunistic infections stand as major factors leading to lower extremities amputations in diabetes. The molecular mechanisms underlying diabetic's torpid healing have not been elucidated. We present the case of a female diabetic patient that after a plantar abscess surgical drainage, tight g...

journal_title：International wound journal

authors： Berlanga-Acosta J,Mendoza-Mari Y,Martínez MD,Valdés-Perez C,Ojalvo AG,Armstrong DG

更新日期：2013-04-01 00:00:00

abstract：:Prevention and treatment of bacterial colonised/infected wounds are critical. Many commercially available silver dressings claim broad-spectrum bactericidal activity over days and are indicated for serious conditions including burns and ulcers. However, there is no peer-reviewed literature available for many newer dre...

journal_title：International wound journal

authors： Cavanagh MH,Burrell RE,Nadworny PL

更新日期：2010-10-01 00:00:00

abstract：:Chronic wounds, including diabetic foot ulcers, pressure ulcers and venous leg ulcers, represent a significant cause of morbidity in developed countries, predominantly in older patients. The aetiology of these wounds is probably multifactorial, but the role of bacteria in their pathogenesis is still unclear. Moreover,...

journal_title：International wound journal

authors： Baffoni M,Bessa LJ,Grande R,Di Giulio M,Mongelli M,Ciarelli A,Cellini L

更新日期：2012-10-01 00:00:00

abstract：:Nicorandil is an original vasodilatator used to control angina by decreasing cardiac preload and afterload. Since 1997, many reports of single or multiple nicorandil-induced ulcerations have been published. To date, eight cases of nicorandil-induced fistula into adjacent organs have been described. The pathogeneses of...

journal_title：International wound journal

authors： Trechot P,Petitpain N,Guy C,Pinzano A,Javot L,Schmutz JL,Marie B,Barbaud A

更新日期：2013-04-01 00:00:00

abstract：:In May 2011, an international panel of wound care experts from multiple disciplines convened to develop this document to summarise the evolution of negative pressure wound therapy (NPWT) technology devices over the past 15 years, specifically concentrating on the V.A.C.(®) Therapy (KCI USA, Inc., San Antonio, TX) fam...

journal_title：International wound journal

authors： Gupta S

更新日期：2012-08-01 00:00:00

abstract：:The aim of the study was to assess the reliability of measuring the cross-sectional area of diabetic foot ulcers using Image J software. The inter- and intra-rater reliability of ulcer area measures were assessed using digital images of acetate tracings of ulcers of the foot affecting 31 participants in an off-loading...

journal_title：International wound journal

authors： Jeffcoate WJ,Musgrove AJ,Lincoln NB

更新日期：2017-12-01 00:00:00

abstract：:Negative pressure wound therapy with instillation and dwell time (NPWTi-d) is an adjunctive therapy that can be used in the management of complex wounds with infection. NPWTi-d incorporates the intermittent instillation of a topical solution to the wound in a programmed manner. Unlike standard negative pressure wound ...

journal_title：International wound journal

authors： Anghel EL,Kim PJ,Attinger CE

更新日期：2016-09-01 00:00:00

abstract：:Continuous delivery of oxygen therapy has been observed to improve healing for individuals with an advanced diabetic foot ulcer (DFU). However, this intervention requires the purchasing of an oxygen delivery device and moist dressings. It is unknown whether this upfront financial investment represents good value for m...

journal_title：International wound journal

authors： Chan BC,Campbell KE

更新日期：2020-12-01 00:00:00

abstract：:Leg ulcer management is complex, time-consuming and of high socio-economic importance. Data on cost-of-illness in leg ulcer care are sparse. The objective of this study was to evaluate the cost-of-illness in leg ulcer treatment in the metropolitan area of Hamburg. About 147 institutions involved in wound care particip...

journal_title：International wound journal

authors： Augustin M,Brocatti LK,Rustenbach SJ,Schäfer I,Herberger K

更新日期：2014-06-01 00:00:00

abstract：:The factors preventing healing in venous leg ulcers are still not fully understood. Iron-mediated tissue damage has been hypothesised, yet anecdotally anaemia is also thought to have a negative effect on wound healing. This article summarises the current evidence for these theories and their likely effects in the cont...

journal_title：International wound journal

authors： Ferris AE,Harding KG

更新日期：2019-12-01 00:00:00

abstract：:Necrobiosis lipoidica is a rare granulomatous disorder of the skin. In up to 30% of the affected patients it can lead to ulcerations, which can impair the quality of life and are also very difficult to treat. Its pathogenesis is not fully understood. Only few studies focussing on necrobiosis lipoidica can be found, bu...

journal_title：International wound journal

authors： Franklin C,Stoffels-Weindorf M,Hillen U,Dissemond J

更新日期：2015-10-01 00:00:00

abstract：:Wound healing is a complex cellular and biochemical process and can be affected by several systemic and local factors. In this study, we aimed to discuss the aetiologic factors of non-healing wounds and the management of this complicated process with current information. The medical data of the patients who were admit...

journal_title：International wound journal

authors： Calis H,Sengul S,Guler Y,Karabulut Z

更新日期：2020-04-01 00:00:00

abstract：:Patients with diabetes mellitus have a lifetime risk of 15% to 25% of developing diabetic foot ulcers (DFUs). DFU is associated with significant morbidity and mortality. Wound imaging systems are useful adjuncts in monitoring of wound progress. Our study aims to review existing literature on the available wound assess...

journal_title：International wound journal

authors： Chan KS,Lo ZJ

更新日期：2020-12-01 00:00:00

abstract：:Biological alternatives to synthetic meshes are increasingly utilised in complex abdominal wall reconstruction. There is a lack of evidence demonstrating that non-cross-linked porcine acellular dermal matrix vascularizes and integrates with human tissue in suboptimal wound conditions. We aimed to evaluate these proper...

journal_title：International wound journal

authors： Gowda AU,Chang SM,Chopra K,Matthews JA,Sabino J,Stromberg JA,Zahiri HR,Pinczewski J,Holton LH 3rd,Silverman RP,Singh DP

更新日期：2016-10-01 00:00:00

abstract：:Nicorandil, a nicotinamide ester, was first reported to be involved in the induction of oral ulcers in 1997. Since then, many reports of single or multiple nicorandil-induced ulcerations (NIUs) have been reported. We hypothesised that in the case of high-dosage nicorandil or after an increased dosage of nicorandil, ni...

journal_title：International wound journal

authors： Trechot P,Jouzeau JY,Brouillard C,Scala-Bertola J,Petitpain N,Cuny JF,Gauchotte G,Schmutz JL,Barbaud A

更新日期：2015-10-01 00:00:00

abstract：:Wound clinics are seeing an increase in the number of 'complex' wounds, which arise as the result of the interaction between multiple coexisting systemic pathologies, environmental factors and local wound factors. These complex wounds require an approach to diagnosis and management that can encapsulate all these facto...

journal_title：International wound journal

authors： Harding K,Gray D,Timmons J,Hurd T

更新日期：2007-06-01 00:00:00

abstract：:Pressure ulcers (PUs) are one of the most prevalent adverse events in acute and chronic care. The root aetiological cause of PUs is sustained cell and tissue deformations, which triggers a synergistic tissue damage cascade that accelerates over relatively short time periods. Changes in skin microclimate conditions are...

journal_title：International wound journal

authors： Schwartz D,Gefen A

更新日期：2020-06-01 00:00:00

abstract：:Negative pressure wound therapy (NPWT) is considered an effective wound treatment, but there are a number of issues that need to be addressed for improvements to be made. This review aimed to explore the literature relating to the pain and skin trauma that may be experienced during NPWT. A literature search was carrie...

journal_title：International wound journal

authors： Upton D,Andrews A

更新日期：2015-02-01 00:00:00

abstract：:A sandwich graft was applied to the debrided cortical bone layer of the tibia in the case of a 72-year-old male patient with full-thickness necrotic burn injury. The combined graft consisted of a dermal template material and autologous split thickness skin graft. After application, the graft was found totally accepted...

journal_title：International wound journal

authors： Gáspár K,Erdei I,Péter Z,Dezsö B,Hunyadi J,Juhász I

更新日期：2006-03-01 00:00:00

abstract：:The initial care of burn wounds and choice of dressing are pivotal to optimally support the healing process. To ensure fast re-epithelialisation within 10-14 days and prevent complications, an optimal healing environment is essential. An innovative dressing based on nanocellulose was used for the treatment of burns in...

journal_title：International wound journal

authors： Resch A,Staud C,Radtke C

更新日期：2021-01-19 00:00:00

abstract：:Although platelet gel is considered one of the most popular tools in the treatment of chronic ulcers, current consensus on its use is not unanimous. A prospective randomised trial was carried out at the Plastic Surgery Unit of the 'Salvatore Maugeri' Foundation Hospital of Pavia (Italy). The study involved 13 patients...

journal_title：International wound journal

authors： Scevola S,Nicoletti G,Brenta F,Isernia P,Maestri M,Faga A

更新日期：2010-06-01 00:00:00

abstract：:Bacterial colonisation and infection remain the major causes of delayed healing and graft rejection following burns. Topical treatment is necessary to reduce the incidence of burn wound infection. Silver sulphadiazine (SD-Ag) is an often used microbicidal agent. However, this treatment produces adverse reactions and s...

journal_title：International wound journal

authors： Peral MC,Martinez MA,Valdez JC

更新日期：2009-02-01 00:00:00

abstract：:The aim of this article was to investigate the effectiveness of testing cold immersion recovery responses in the diabetic foot with neuropathy using a contact thermography system based on thermochromic liquid crystals. A total of 81 subjects with no history of diabetic foot ulceration were assigned to neuropathy, non ...

journal_title：International wound journal

authors： Bharara M,Viswanathan V,Cobb JE

更新日期：2008-10-01 00:00:00

abstract：:Indwelling foreign-body infections are a critical medical problem, especially in immunocompromised patients. To examine the pathogenicity of biofilm-forming bacteria settling on foreign materials, mice implanted with plastic discs were infected with Staphylococcus aureus. After opening a wide subcutaneous pocket on th...

journal_title：International wound journal

authors： Makino T,Jimi S,Oyama T,Nakano Y,Hamamoto K,Mamishin K,Yahiro T,Hara S,Takata T,Ohjimi H

更新日期：2015-04-01 00:00:00

abstract：:Pressure injuries are key clinical indicators of care standard. In Australia, pressure injuries increase length of hospital stay by 4.31 and cost $285 million annually. This pilot study examined the effectiveness of sacral dressing in reducing the prevalence of pressure injuries in older, high-risk patients. A non ran...

journal_title：International wound journal

authors： Cubit K,McNally B,Lopez V

更新日期：2013-10-01 00:00:00

abstract：:The use of a rigid disc as a barrier between the wound bed and the wound filler during negative pressure wound therapy (NPWT) has been suggested to prevent damage to exposed organs. However, it is important to determine that the effects of NPWT, such as wound contraction and fluid removal, are maintained during treatm...

journal_title：International wound journal

authors： Anesäter E,Roupé KM,Robertsson P,Borgquist O,Torbrand C,Ingemansson R,Lindstedt S,Malmsjö M

更新日期：2011-08-01 00:00:00

abstract：:Several researches have shown that negative-pressure wound dressings can secure split-thickness skin grafts and improve graft survival. However, in anatomically difficult body regions such as the perineum it is questionable whether these dressings have similar beneficial effects. In this study, we evaluated the effect...

journal_title：International wound journal

authors： Lee KT,Pyon JK,Lim SY,Mun GH,Oh KS,Bang SI

更新日期：2014-04-01 00:00:00

abstract：:Assess the outcome of a standardised protocol for the treatment of post-operative wound infection in patients undergoing deformity correction for neuro-muscular scoliosis (NMS). Retrospective review of 443 consecutive patients with a minimum 18 months' follow-up, following a primary posterior deformity correction for ...

journal_title：International wound journal

authors： Haleem S,Edwin J,Bashir MA,Soltani S,Nadarajah R,Kieser DC

更新日期：2020-06-01 00:00:00

abstract：:The pathogenesis of hypertrophic scar (HS) is still poorly understood. Macrophages, especially the polarisation of that to M1 or M2, play a pivotal role in control of the degree of scar formation. Profiling of macrophage phenotypes in human specimens during long-term period of wound healing and HS formation may provid...

journal_title：International wound journal

authors： Chen L,Wang J,Li S,Yu Z,Liu B,Song B,Su Y

更新日期：2019-04-01 00:00:00