The clinical dynamic changes of macrophage phenotype and function in different stages of human wound healing and hypertrophic scar formation.

abstract：:The World Health Assembly declared 2020, the International Year of the Nurse and the Midwife. Recent editorials and commentaries support the leading role of nurses and midwives as frontline caregivers emphasizing the need to invest in the nursing workforce worldwide to meet global health needs. Today nurses are also l...

journal_title：International wound journal

authors： Gethin G,Probst S,Weller C,Kottner J,Beeckman D

更新日期：2020-12-01 00:00:00

abstract：:Chronic non-healing wounds are a burden in the Long-Term Care (LTC) sector, increasing costs, morbidity, and mortality and causing pain and suffering. The objective of this LTC Innovation pilot was to test the value of a promising new neuromuscular stimulation device in elevating the experience and satisfaction of the...

journal_title：International wound journal

authors： Harris C,Ramage D,Boloorchi A,Vaughan L,Kuilder G,Rakas S

更新日期：2019-02-01 00:00:00

abstract：:Previous studies have reported that the use of incisional negative pressure wound therapy (INPWT) might reduce the incidence of wound infections, although its mechanism remains unknown. We designed a prospective study to explore the effects of INPWT on different stages of the wound healing process. After meeting the i...

journal_title：International wound journal

authors： Rashed A,Csiszar M,Beledi A,Gombocz K

更新日期：2020-11-25 00:00:00

abstract：:Surgical site infections are the most common nosocomial infections in surgical patients. The preventable and the unmodifiable risk factors for deep sternal wound infections (DSWI) have been amply assessed in the literature. The aim of this review was to describe the results of the numerous published studies to describ...

journal_title：International wound journal

authors： Buja A,Zampieron A,Cavalet S,Chiffi D,Sandonà P,Vinelli A,Baldovin T,Baldo V

更新日期：2012-08-01 00:00:00

abstract：:Perianal fistula is a common disease that affects particular patients with inflammatory bowel disease. Honey has been used as a natural remedy for centuries for the treatment of various disorders. We report a patient with persistent fistulas, in whom conventional medical and surgical therapy failed. In this case, most...

journal_title：International wound journal

authors： Vlcekova P,Krutakova B,Takac P,Kozanek M,Salus J,Majtan J

更新日期：2012-02-01 00:00:00

abstract：:Negative pressure wound therapy (NPWT) is considered an effective wound treatment, but there are a number of issues that need to be addressed for improvements to be made. This review aimed to explore the literature relating to the pain and skin trauma that may be experienced during NPWT. A literature search was carrie...

journal_title：International wound journal

authors： Upton D,Andrews A

更新日期：2015-02-01 00:00:00

abstract：:This study developed a measuring instrument of pressure-injury risk assessment competence for nursing education adopting theoretical procedures based on competence structuration to support the psychometric quality. The objective of this study is testing the psychometric properties of the instrument using simulation st...

journal_title：International wound journal

authors： Moura ECC,Peres AM,Caliri MHL,Lopez V,F Soares S

更新日期：2020-06-01 00:00:00

abstract：:Continuous delivery of oxygen therapy has been observed to improve healing for individuals with an advanced diabetic foot ulcer (DFU). However, this intervention requires the purchasing of an oxygen delivery device and moist dressings. It is unknown whether this upfront financial investment represents good value for m...

journal_title：International wound journal

authors： Chan BC,Campbell KE

更新日期：2020-12-01 00:00:00

abstract：:Cushing's syndrome is a condition caused by high levels of glucocorticoids, or most commonly as a result of prolonged exposure to exogenous steroids. Clinical features include diabetes, hypertension, obesity, skin atrophy, immune suppression and delayed wound healing. We report a patient with iatrogenic Cushing's synd...

journal_title：International wound journal

authors： Biswas M,Gibby O,Ivanova-Stoilova T,Harding K

更新日期：2011-02-01 00:00:00

abstract：:Non healing diabetic foot ulcers and the resulting potential amputations present significant costs to the health care system and reduce patient quality of life. The goal of diabetic foot ulcer treatment is to obtain wound closure as expeditiously as possible. The use of platelet-rich plasma (PRP) to enhance wound heal...

journal_title：International wound journal

authors： Saad Setta H,Elshahat A,Elsherbiny K,Massoud K,Safe I

更新日期：2011-06-01 00:00:00

abstract：:Silver nanoparticles are gaining importance as an antimicrobial agent in wound dressings. Chitin is a biopolymer envisioned to promote rapid dermal regeneration and accelerate wound healing. This study was focused on the evaluation of chitin membranes containing silver nanoparticles for use as an antimicrobial wound d...

journal_title：International wound journal

authors： Singh R,Singh D

更新日期：2014-06-01 00:00:00

abstract：:Nicorandil is an original vasodilatator used to control angina by decreasing cardiac preload and afterload. Since 1997, many reports of single or multiple nicorandil-induced ulcerations have been published. To date, eight cases of nicorandil-induced fistula into adjacent organs have been described. The pathogeneses of...

journal_title：International wound journal

authors： Trechot P,Petitpain N,Guy C,Pinzano A,Javot L,Schmutz JL,Marie B,Barbaud A

更新日期：2013-04-01 00:00:00

abstract：:The aim of this study was to investigate the relationship between perioperative corticosteroids administration and the incidence of pressure ulcers (PUs) in cardiovascular surgical patients. A retrospective analysis was performed on data from consecutive patients who had cardiac surgery in 2012. Univariate and multiva...

journal_title：International wound journal

authors： Chen HL,Shen WQ,Xu YH,Zhang Q,Wu J

更新日期：2015-10-01 00:00:00

abstract：:Covering the reconstructed area with a healthy soft-tissue envelope is a major challenge after limb-sparing surgery in patients with malignant bone and soft-tissue tumours. Negative pressure wound therapy (NPWT) of open wounds hastens healing and minimises the requirement for complex reconstructive soft-tissue surgery...

journal_title：International wound journal

authors： Mermerkaya U,Bekmez S,Alkan E,Ayvaz M,Tokgozoglu M

更新日期：2016-06-01 00:00:00

abstract：:Acellular dermal matrices can successfully heal wounds. This study's goal was to compare clinical outcomes of a novel, open-structure human reticular acellular dermis matrix (HR-ADM) to facilitate wound closure in non-healing diabetic foot ulcers (DFUs) versus DFUs treated with standard of care (SOC). Following a 2-we...

journal_title：International wound journal

authors： Zelen CM,Orgill DP,Serena T,Galiano R,Carter MJ,DiDomenico LA,Keller J,Kaufman J,Li WW

更新日期：2017-04-01 00:00:00

abstract：:Podologists are nurses who care for the diabetic foot (orthotics, offloading devices, blisters, calluses, treatment of fungus infection and patient education). In contrast to podiatrists, they are not qualified to perform any surgical treatment or wound care. We analysed whether there is an association between the dec...

journal_title：International wound journal

authors： Kröger K,Moysidis T,Feghaly M,Schäfer E,Bufe A,Initiative Chronische Wunden e.V., Germany.

更新日期：2016-10-01 00:00:00

abstract：:This review and case study report considers the evidence to indicate that the progress of wound healing is negatively affected by the presence of stressors and in circumstances where patients are in pain. It considers the relationship between perceptions of pain, stress and delayed wound healing with a specific focus ...

journal_title：International wound journal

authors： Matsuzaki K,Upton D

更新日期：2013-12-01 00:00:00

abstract：:Hydrofluoric acid (HF) burns cause immediate damage and painful long-term sequellae. Traditionally, chelating agents have been used as the initial treatment for such burns. We have introduced epidermal growth factor (EGF) into an HF model to compare EGF with Ca(2+) and Mg(2+) treatments; 40 Sprague Dawley rats were di...

journal_title：International wound journal

authors： Songur MK,Akdemir O,Lineaweaver WC,Cavusoglu T,Ozsarac M,Aktug H,Songur E,Tiftikcioglu YO

更新日期：2015-12-01 00:00:00

abstract：:Reducing and preventing postoperative pain are currently a topic of great interest. There are different modalities for providing analgesia that can provide an alternative or adjunct to opioid therapy. One mode of therapy involves the use of portable pain pump devices that can deliver continuous local anaesthesia direc...

journal_title：International wound journal

authors： Scimeca CL,Fisher TK,Bharara M,Armstrong DG

更新日期：2010-06-01 00:00:00

abstract：:Wound healing is a complex cellular and biochemical process and can be affected by several systemic and local factors. In this study, we aimed to discuss the aetiologic factors of non-healing wounds and the management of this complicated process with current information. The medical data of the patients who were admit...

journal_title：International wound journal

authors： Calis H,Sengul S,Guler Y,Karabulut Z

更新日期：2020-04-01 00:00:00

abstract：:A study conducted in an Australian home nursing service sought to ascertain whether the provision of funding for compression bandaging and medical footwear would impact on compression therapy use, wound healing and quality of life (QoL) among people with venous leg ulcers. Clients (n = 120) were randomly allocated to ...

journal_title：International wound journal

authors： Kapp S,Miller C,Elder K

更新日期：2012-10-01 00:00:00

abstract：:The purpose of this analysis was to evaluate the use of DermaPure, a decellularised human skin allograft, in the treatment of a variety of challenging wounds. This retrospective observational analysis reviewed a total of 37 patients from 29 different wound clinics across the USA. Each patient received one application ...

journal_title：International wound journal

authors： Kimmel H,Gittleman H

更新日期：2017-08-01 00:00:00

abstract：:Pre-tibial lacerations are complex wounds affecting a primarily aged population, with poor healing and a potentially significant impact on social well-being. Management of these wounds has changed little in 20 years, despite significant advances in wound care. A retrospective observational study was undertaken to obse...

journal_title：International wound journal

authors： McClelland HM,Stephenson J,Ousey KJ,Gillibrand WP,Underwood P

更新日期：2012-06-01 00:00:00

abstract：:Negative pressure wound therapy (NPWT) is an established method for the faster wound healing of chronic non-healing wounds. It is also used for laparostomy wounds and healing of split skin grafts. The commercially available machine and the consumables for NPWT are very expensive and economically not feasible in develo...

journal_title：International wound journal

authors： Gopal SV,Solomon A

更新日期：2019-02-01 00:00:00

abstract：:Pathogenic, opportunistic, and commensal bacterial coexist in the intestinal tract, and imbalances among these strains have been linked to systemic inflammation and a variety of disease states. Similarly, human skin plays an important role as an interface between the body and the environment with an estimated 1 billio...

journal_title：International wound journal

authors： Knackstedt R,Knackstedt T,Gatherwright J

更新日期：2020-12-01 00:00:00

abstract：:Wound dehiscence is a surgical complication caused by the application of opposing and distracting forces tending to pull apart the suture line. In recent years, a novel negative pressure surgical management system has been developed to prevent surgical wound complications. This system creates a closed environment that...

journal_title：International wound journal

authors： Bollero D,Malvasio V,Catalano F,Stella M

更新日期：2015-02-01 00:00:00

abstract：:Mohs micrographic surgery is the best therapeutical option for hand squamous cell carcinoma without bone involvement; however, the reconstruction of the surgical defect could be very difficult if the tumour is located in the distal phalanx of a finger. We present the case of a patient with a squamous cell carcinoma of...

journal_title：International wound journal

authors： Magliano J,Rossi V,Turra N,Bazzano C

更新日期：2019-06-01 00:00:00

abstract：:Although platelet gel is considered one of the most popular tools in the treatment of chronic ulcers, current consensus on its use is not unanimous. A prospective randomised trial was carried out at the Plastic Surgery Unit of the 'Salvatore Maugeri' Foundation Hospital of Pavia (Italy). The study involved 13 patients...

journal_title：International wound journal

authors： Scevola S,Nicoletti G,Brenta F,Isernia P,Maestri M,Faga A

更新日期：2010-06-01 00:00:00

abstract：:The critical problem of post-burn depigmentation is the lacking normal melanocytes. Auto-skin grafting and autologous non-cultured epidermal cell suspension have been used to improve the appearance. However, a large amount of skin graft is required of donor sites in the former method, while the latter method is though...

journal_title：International wound journal

authors： Chen B,Xu M,Li B

更新日期：2017-02-01 00:00:00

abstract：:Health care-associated infections in hospitals, including surgical site infections, contribute significantly to morbidity as well as mortality. Surgical incision management (SIM) using negative pressure wound therapy (Prevena™ Incision Management System, Kinetic Concepts, Inc., San Antonio, TX, USA) is designed to cov...

journal_title：International wound journal

authors： Weir G

更新日期：2014-06-01 00:00:00