A prospective, randomised, controlled, multicentre clinical trial examining healing rates, safety and cost to closure of an acellular reticular allogenic human dermis versus standard of care in the treatment of chronic diabetic foot ulcers.

abstract：:The aim of the study was to assess the reliability of measuring the cross-sectional area of diabetic foot ulcers using Image J software. The inter- and intra-rater reliability of ulcer area measures were assessed using digital images of acetate tracings of ulcers of the foot affecting 31 participants in an off-loading...

journal_title：International wound journal

authors： Jeffcoate WJ,Musgrove AJ,Lincoln NB

更新日期：2017-12-01 00:00:00

abstract：:The aim of this study was to gain a better understanding of the venous leg ulcer (VLU) management in primary health care settings located in Melbourne metropolitan and rural Victoria, Australia. We explored health professionals' perspective on the use of the Australian and New Zealand Venous Leg Ulcer Clinical Practic...

journal_title：International wound journal

authors： Weller CD,Richards C,Turnour L,Team V

更新日期：2020-06-01 00:00:00

abstract：:Cushing's syndrome is a condition caused by high levels of glucocorticoids, or most commonly as a result of prolonged exposure to exogenous steroids. Clinical features include diabetes, hypertension, obesity, skin atrophy, immune suppression and delayed wound healing. We report a patient with iatrogenic Cushing's synd...

journal_title：International wound journal

authors： Biswas M,Gibby O,Ivanova-Stoilova T,Harding K

更新日期：2011-02-01 00:00:00

abstract：:Ulcers in radiated skin continue to be a challenge for health care practitioners. Healing impairment in the setting of radiation-damaged tissue will most of the time lead to chronic wounds that reduce the patient's quality of life. In this review, we present an update of the pathophysiology of tissue damage caused by ...

journal_title：International wound journal

authors： Olascoaga A,Vilar-Compte D,Poitevin-Chacón A,Contreras-Ruiz J

更新日期：2008-06-01 00:00:00

abstract：:Wound bed preparation (WBP) is an integral part of the care programme for chronic wounds. The acronym TIME is used in the context of WBP and describes four barriers to healing in chronic wounds; namely, dead Tissue, Infection and inflammation, Moisture imbalance and a non-migrating Edge. Larval debridement therapy (LD...

journal_title：International wound journal

authors： Pritchard DI,Čeřovský V,Nigam Y,Pickles SF,Cazander G,Nibbering PH,Bültemann A,Jung W

更新日期：2016-08-01 00:00:00

abstract：:Pressure injuries are one of the most common and costly complications occurring in US hospitals. With up to 3 million patients affected each year, hospital-acquired pressure injuries (HAPIs) place a substantial burden on the US healthcare system. In the current study, US hospital discharge records from 9.6 million pat...

journal_title：International wound journal

authors： Wassel CL,Delhougne G,Gayle JA,Dreyfus J,Larson B

更新日期：2020-12-01 00:00:00

abstract：:Leg ulcer management is complex, time-consuming and of high socio-economic importance. Data on cost-of-illness in leg ulcer care are sparse. The objective of this study was to evaluate the cost-of-illness in leg ulcer treatment in the metropolitan area of Hamburg. About 147 institutions involved in wound care particip...

journal_title：International wound journal

authors： Augustin M,Brocatti LK,Rustenbach SJ,Schäfer I,Herberger K

更新日期：2014-06-01 00:00:00

abstract：:Infiltration of surgical wounds with long-acting local anaesthetics (LA) is used to reduce postoperative incisional pain. We hypothesised that infiltration with LA interferes with wound healing in rats. Seventy-two rats were allocated into nine groups. After intraperitoneal anaesthesia, the interscapular dorsal region...

journal_title：International wound journal

authors： Abrão J,Fernandes CR,White PF,Shimano AC,Okubo R,Lima GB,Bachur JA,Garcia SB

更新日期：2014-08-01 00:00:00

abstract：:The aims of this randomised controlled study were to determine whether the application of silicone adhesive dressings with standard preventive care would reduce the impairment of skin integrity and to evaluate the subepidermal moisture (SEM) value in anatomical locations to predict impairment of skin integrity. Of the...

journal_title：International wound journal

authors： Lee YJ,Kim JY,Shin WY

更新日期：2019-03-01 00:00:00

abstract：:The aim of the study was to compare three sampling techniques used in routine diagnostics to identify the microbiota in chronic venous leg ulcers. A total of 46 patients with persisting venous leg ulcers were included in the study. At inclusion, swab, biopsy and filter paper pad samples were collected. After 4 weeks, ...

journal_title：International wound journal

authors： Gjødsbøl K,Skindersoe ME,Christensen JJ,Karlsmark T,Jørgensen B,Jensen AM,Klein BM,Sonnested MK,Krogfelt KA

更新日期：2012-06-01 00:00:00

abstract：:Chronic wounds are a growing challenge for physicians and health insurance agencies. The burden of affected patients is enormous, because of pain but also because of long-lasting therapies and dependence on nursing services. In other areas of medicine, computer-based diagnostics is established, yet, accurate wound doc...

journal_title：International wound journal

authors： Stremitzer S,Wild T,Hoelzenbein T

更新日期：2007-06-01 00:00:00

abstract：:Skin grafting is one of the most common surgical procedures in the area of non-healing wounds by which skin or a skin substitute is placed over a wound to replace and regenerate the damaged skin. Chronic leg ulcers are an important problem and a major source of expense for Western countries and for which many differen...

journal_title：International wound journal

authors： Serra R,Rizzuto A,Rossi A,Perri P,Barbetta A,Abdalla K,Caroleo S,Longo C,Amantea B,Sammarco G,de Franciscis S

更新日期：2017-02-01 00:00:00

abstract：:Hydrofluoric acid (HF) burns cause immediate damage and painful long-term sequellae. Traditionally, chelating agents have been used as the initial treatment for such burns. We have introduced epidermal growth factor (EGF) into an HF model to compare EGF with Ca(2+) and Mg(2+) treatments; 40 Sprague Dawley rats were di...

journal_title：International wound journal

authors： Songur MK,Akdemir O,Lineaweaver WC,Cavusoglu T,Ozsarac M,Aktug H,Songur E,Tiftikcioglu YO

更新日期：2015-12-01 00:00:00

abstract：:Even though it is estimated that at least 300 000 people in Canada may be affected by chronic oedema/lymphoedema, recognition of the seriousness of this chronic disease in health care is scarce. Lymphoedema affects up to 70% of breast and prostate cancer patients, substantially increasing their postoperative medical c...

journal_title：International wound journal

authors： Keast DH,Despatis M,Allen JO,Brassard A

更新日期：2015-06-01 00:00:00

abstract：:Wound chronification and opportunistic infections stand as major factors leading to lower extremities amputations in diabetes. The molecular mechanisms underlying diabetic's torpid healing have not been elucidated. We present the case of a female diabetic patient that after a plantar abscess surgical drainage, tight g...

journal_title：International wound journal

authors： Berlanga-Acosta J,Mendoza-Mari Y,Martínez MD,Valdés-Perez C,Ojalvo AG,Armstrong DG

更新日期：2013-04-01 00:00:00

abstract：:An educational programme in wound healing was developed in France in 1998. The course lasts for 1 year and consists of 100 hours of interactive education including wound-healing principles, management of pressure ulcers, leg ulcers, diabetic foot ulcers, burns and trauma. The programme mixes theoretical and practical ...

journal_title：International wound journal

authors： Meaume S,Téot L,Dereure O

更新日期：2005-06-01 00:00:00

abstract：:Immunosuppressive therapy is increasingly being used in clinical practice and has been shown to affect wound healing to varying degrees. This article looks at the effects of the newer immunosuppressive agents on wound healing. It is shown that wound healing is impaired via different mechanisms. Some of the animal and ...

journal_title：International wound journal

authors： Bootun R

更新日期：2013-02-01 00:00:00

abstract：:We demonstrate sodium pyruvate (NaPy) pre-treatment as a successful approach for pressure ulcer (PU) prevention by averting their aetiological origin-cell-level damage and death by large, sustained mechanical loads. We evaluated the NaPy pre-treatment effect on permeability changes in the cell's plasma membrane (PM) f...

journal_title：International wound journal

authors： Alvarez-Elizondo MB,Barenholz-Cohen T,Weihs D

更新日期：2019-10-01 00:00:00

abstract：:Tendinopathy is a very common disease in the general population as well as in athletes. The aim of the present study was to examine the tendon thickness and cross-sectional area (CSA) in subjects with chronic mid-portion Achilles tendinopathy (AT) who engaged in either an eccentric exercise (EE) programme with vibrati...

journal_title：International wound journal

authors： Romero-Morales C,Javier Martín-Llantino P,Calvo-Lobo C,Palomo-López P,López-López D,Fernández-Carnero J,Rodríguez-Sanz D

更新日期：2019-04-01 00:00:00

abstract：:Silver nanoparticles are gaining importance as an antimicrobial agent in wound dressings. Chitin is a biopolymer envisioned to promote rapid dermal regeneration and accelerate wound healing. This study was focused on the evaluation of chitin membranes containing silver nanoparticles for use as an antimicrobial wound d...

journal_title：International wound journal

authors： Singh R,Singh D

更新日期：2014-06-01 00:00:00

abstract：:Pressure ulcers (PUs) are a common secondary complication experienced by community dwelling individuals with spinal cord injury (SCI). There is a paucity of literature on the health economic impact of PU in SCI population from a societal perspective. The objective of this study was to determine the resource use and co...

journal_title：International wound journal

authors： Chan BC,Nanwa N,Mittmann N,Bryant D,Coyte PC,Houghton PE

更新日期：2013-08-01 00:00:00

abstract：:We present a new surgical modification to allow propeller perforator flaps to cover pressure sores at various locations. We used a propeller perforator flap concept based on the detection of newly formed perforator vessels located 1 cm from the wound margin and stimulated by the chronic inflammation process. Between J...

journal_title：International wound journal

authors： Kelahmetoglu O,Van Landuyt K,Yagmur C,Sommeling CE,Keles MK,Tayfur V,Simsek T,Demirtas Y,Guneren E

更新日期：2017-12-01 00:00:00

abstract：:Iodine-based products are antibacterial. The small iodine molecular size is ideally suited to treat surface critical colonisation. Inadine is a 10% povidone iodine dressing with the equivalent of 1% available iodine that is easily extracted from the viscose backing by serum or exudate. The use of hydrophilic polyethyl...

journal_title：International wound journal

authors： Sibbald RG,Elliott JA

更新日期：2017-04-01 00:00:00

abstract：:Deep sternal wound infection (DSWI) is a fatal complication after median sternotomy. This study was to assess the effect of vacuum-assisted closure (VAC) combined with bi-pectoral muscle advancement flap therapy on rehabilitation for the treatment of DSWI. Fifty-two patients with DSWI underwent treatment of VAC and bi...

journal_title：International wound journal

authors： Wang C,Zhang J,Liu Z

更新日期：2020-04-01 00:00:00

abstract：:Marjolin's ulcer refers to malignant degeneration in a chronic wound. Although originally described in an area of burns scar, many other chronic wounds such as osteomyelitis sinus tracts, venous stasis ulcers and chronic pressure sores have the potential to undergo malignant transformation. We present an interesting c...

journal_title：International wound journal

authors： Fairbairn NG,Hamilton SA

更新日期：2011-10-01 00:00:00

abstract：:Keratin proteins have been shown to play a key role in wound healing. Controlled keratin gene (KRT) expression promotes cell growth, migration and differentiation, and as an example of the importance of keratin proteins, absence of KRT17 has been shown to delay wound closure. In addition, downregulation of KRT6 and KR...

journal_title：International wound journal

authors： Batzer AT,Marsh C,Kirsner RS

更新日期：2016-02-01 00:00:00

abstract：:Venous leg ulcers are the most common form of non-healing leg ulcers. They are subjected to treatments such as topical medications, dressings, and compression therapies. This can lead to exposure to a number of allergens with subsequent sensitisation and contact dermatitis of the regional skin. This may contribute to ...

journal_title：International wound journal

authors： Rai R,Shenoy MM,Viswanath V,Sarma N,Majid I,Dogra S

更新日期：2018-08-01 00:00:00

abstract：:This study aimed to demonstrate the antibacterial effects of bupivacaine and prilocaine on Escherichia coli, Staphylococcus aureus, and Pseudomonas aeruginosa. In our study, the in vitro antimicrobial effects of 20 mg/mL prilocaine and 5 mg/mL bupivacaine were tested against a S. aureus American-type culture collectio...

journal_title：International wound journal

authors： Kesici S,Demirci M,Kesici U

更新日期：2019-10-01 00:00:00

abstract：:Nicorandil, a nicotinamide ester, was first reported to be involved in the induction of oral ulcers in 1997. Since then, many reports of single or multiple nicorandil-induced ulcerations (NIUs) have been reported. We hypothesised that in the case of high-dosage nicorandil or after an increased dosage of nicorandil, ni...

journal_title：International wound journal

authors： Trechot P,Jouzeau JY,Brouillard C,Scala-Bertola J,Petitpain N,Cuny JF,Gauchotte G,Schmutz JL,Barbaud A

更新日期：2015-10-01 00:00:00

abstract：:The World Health Assembly declared 2020, the International Year of the Nurse and the Midwife. Recent editorials and commentaries support the leading role of nurses and midwives as frontline caregivers emphasizing the need to invest in the nursing workforce worldwide to meet global health needs. Today nurses are also l...

journal_title：International wound journal

authors： Gethin G,Probst S,Weller C,Kottner J,Beeckman D

更新日期：2020-12-01 00:00:00