Wound healing in radiated skin: pathophysiology and treatment options.

abstract：:Reducing and preventing postoperative pain are currently a topic of great interest. There are different modalities for providing analgesia that can provide an alternative or adjunct to opioid therapy. One mode of therapy involves the use of portable pain pump devices that can deliver continuous local anaesthesia direc...

journal_title：International wound journal

authors： Scimeca CL,Fisher TK,Bharara M,Armstrong DG

更新日期：2010-06-01 00:00:00

abstract：:Patients with rheumatoid arthritis may develop leg ulcers of varied aetiologies, including venous disease, infection and inflammation (vasculitis or pyoderma gangrenosum). The leg ulcers in rheumatoid arthritis patients may involve several of these aetiological factors and are often difficult to heal. Both the ulcers ...

journal_title：International wound journal

authors： Coelho S,Amarelo M,Ryan S,Reddy M,Sibbald RG

更新日期：2004-04-01 00:00:00

abstract：:A case study reporting on the successful treatment of a patient affected by a basal cell carcinoma is submitted. Because the carcinoma had infiltrated deeply, a wide excision was necessary, including the removal of bone tissue. The deep tissue defect was treated with PROMOGRAN* Matrix, a protease-modulating matrix, to...

journal_title：International wound journal

authors： Tausche AK,Sebastian G

更新日期：2005-09-01 00:00:00

abstract：:A 16-year-old girl with pyoderma gangrenosum (PG)-like skin lesions on the extremities, trunk and face developed Takayasu's arteritis (TA; pulseless disease). After 3 years under maintenance cyclosporin A therapy, the patient developed an ischaemic cerebral accident. Severe obstruction of both subclavian and left caro...

journal_title：International wound journal

authors： Dourmishev AL,Serafimova DK,Vassileva SG,Dourmishev LA,Schwartz RA

更新日期：2005-12-01 00:00:00

abstract：:The aim of the study was to compare three sampling techniques used in routine diagnostics to identify the microbiota in chronic venous leg ulcers. A total of 46 patients with persisting venous leg ulcers were included in the study. At inclusion, swab, biopsy and filter paper pad samples were collected. After 4 weeks, ...

journal_title：International wound journal

authors： Gjødsbøl K,Skindersoe ME,Christensen JJ,Karlsmark T,Jørgensen B,Jensen AM,Klein BM,Sonnested MK,Krogfelt KA

更新日期：2012-06-01 00:00:00

abstract：:Nicorandil, a nicotinamide ester, was first reported to be involved in the induction of oral ulcers in 1997. Since then, many reports of single or multiple nicorandil-induced ulcerations (NIUs) have been reported. We hypothesised that in the case of high-dosage nicorandil or after an increased dosage of nicorandil, ni...

journal_title：International wound journal

authors： Trechot P,Jouzeau JY,Brouillard C,Scala-Bertola J,Petitpain N,Cuny JF,Gauchotte G,Schmutz JL,Barbaud A

更新日期：2015-10-01 00:00:00

abstract：:Deep sternal wound infection (DSWI) is a fatal complication after median sternotomy. This study was to assess the effect of vacuum-assisted closure (VAC) combined with bi-pectoral muscle advancement flap therapy on rehabilitation for the treatment of DSWI. Fifty-two patients with DSWI underwent treatment of VAC and bi...

journal_title：International wound journal

authors： Wang C,Zhang J,Liu Z

更新日期：2020-04-01 00:00:00

abstract：:Pressure injuries (PIs) have now become a common complication of the elderly patients. Some studies have observed that pressure injuries may increase mortality, but this area of evidence has not been evaluated and summarised. The aim of this study was to compare the mortality of patients with pressure injuries and tho...

journal_title：International wound journal

authors： Song YP,Shen HW,Cai JY,Zha ML,Chen HL

更新日期：2019-12-01 00:00:00

abstract：:Wound healing is a complex cellular and biochemical process and can be affected by several systemic and local factors. In this study, we aimed to discuss the aetiologic factors of non-healing wounds and the management of this complicated process with current information. The medical data of the patients who were admit...

journal_title：International wound journal

authors： Calis H,Sengul S,Guler Y,Karabulut Z

更新日期：2020-04-01 00:00:00

abstract：:Continuous delivery of oxygen therapy has been observed to improve healing for individuals with an advanced diabetic foot ulcer (DFU). However, this intervention requires the purchasing of an oxygen delivery device and moist dressings. It is unknown whether this upfront financial investment represents good value for m...

journal_title：International wound journal

authors： Chan BC,Campbell KE

更新日期：2020-12-01 00:00:00

abstract：:Breast cancer is a serious disease in women. We estimated the global technical success rate and complication rates of percutaneous vacuum-assisted breast biopsy (VABB). PubMed, Embase, Web of Science, and Scopus databases were retrieved up to July 2018 to find studies in which technical success rate and complication r...

journal_title：International wound journal

authors： Fang M,Liu G,Luo G,Wu T

更新日期：2019-12-01 00:00:00

abstract：:Recent studies have indicated the potential benefits of Non-thermal atmospheric pressure plasma (NTAPP) as a novel therapeutic approach. The purpose of the current study was thus to assess the effect of NTAPP on gingival wound healing. Fifteen patients with bilaterally symmetrical gingival hyperplasia were included in...

journal_title：International wound journal

authors： Kusakci-Seker B,Demirayak-Akdemir M

更新日期：2020-10-01 00:00:00

abstract：:In addition to clinical signs of infection (e.g. inflammation, purulence and pain), a microbial count of ≥105 colony-forming units/g has historically been used to define wound infection. However, it is increasingly recognised that, rather than a high bioburden level alone being detrimental to wound healing, it is the ...

journal_title：International wound journal

authors： Lindsay S,Oates A,Bourdillon K

更新日期：2017-12-01 00:00:00

abstract：:The factors preventing healing in venous leg ulcers are still not fully understood. Iron-mediated tissue damage has been hypothesised, yet anecdotally anaemia is also thought to have a negative effect on wound healing. This article summarises the current evidence for these theories and their likely effects in the cont...

journal_title：International wound journal

authors： Ferris AE,Harding KG

更新日期：2019-12-01 00:00:00

abstract：:Chemotaxis, mitogenesis, motogenesis and cytoprotection are common cellular events involved in both tumourigenesis and tissue repair, which appear amplified upon growth factors exposure. Epidermal growth factor (EGF) promotes these events in epithelial and mesenchymal cells through the binding to a specific tyrosine k...

journal_title：International wound journal

authors： Berlanga-Acosta J,Gavilondo-Cowley J,López-Saura P,González-López T,Castro-Santana MD,López-Mola E,Guillén-Nieto G,Herrera-Martinez L

更新日期：2009-10-01 00:00:00

abstract：:The use of lavage was compared to negative pressure wound therapy (NPWT) with instillation (NPWTi) to assess extent of soft tissue damage, debris removal and environmental cross-contamination susceptibility in three distinct models. Scanning electron microscopy in an ex vivo model showed increased visible tissue traum...

journal_title：International wound journal

authors： Allen D,LaBarbera LA,Bondre IL,Lessing MC,Rycerz AM,Kilpadi DV,Collins BA,Perkins J,McNulty AK

更新日期：2014-04-01 00:00:00

abstract：:Acellular dermal matrices can successfully heal wounds. This study's goal was to compare clinical outcomes of a novel, open-structure human reticular acellular dermis matrix (HR-ADM) to facilitate wound closure in non-healing diabetic foot ulcers (DFUs) versus DFUs treated with standard of care (SOC). Following a 2-we...

journal_title：International wound journal

authors： Zelen CM,Orgill DP,Serena T,Galiano R,Carter MJ,DiDomenico LA,Keller J,Kaufman J,Li WW

更新日期：2017-04-01 00:00:00

abstract：:The critical problem of post-burn depigmentation is the lacking normal melanocytes. Auto-skin grafting and autologous non-cultured epidermal cell suspension have been used to improve the appearance. However, a large amount of skin graft is required of donor sites in the former method, while the latter method is though...

journal_title：International wound journal

authors： Chen B,Xu M,Li B

更新日期：2017-02-01 00:00:00

abstract：:An understanding of risk factors associated with mortality among pressure ulcer patients can inform prognostic counselling and treatment plans. This retrospective cohort study examined associations of comorbid illness, demographic characteristics and laboratory values with 90-day and 90- to 180-day mortality in adult ...

journal_title：International wound journal

authors： Flattau A,Blank AE

更新日期：2014-02-01 00:00:00

abstract：:Gethin G, Cowman S. Case series of use of Manuka honey in leg ulceration. Abstract The historical and current literature reports the successful use of honey to manage a diversity of wound aetiologies. However, only in the last 40 years is research on its mode of action and contribution to wound healing being investiga...

journal_title：International wound journal

authors： Gethin G,Cowman S

更新日期：2005-03-01 00:00:00

abstract：:Necrobiosis lipoidica is a rare granulomatous disorder of the skin. In up to 30% of the affected patients it can lead to ulcerations, which can impair the quality of life and are also very difficult to treat. Its pathogenesis is not fully understood. Only few studies focussing on necrobiosis lipoidica can be found, bu...

journal_title：International wound journal

authors： Franklin C,Stoffels-Weindorf M,Hillen U,Dissemond J

更新日期：2015-10-01 00:00:00

abstract：:Biological alternatives to synthetic meshes are increasingly utilised in complex abdominal wall reconstruction. There is a lack of evidence demonstrating that non-cross-linked porcine acellular dermal matrix vascularizes and integrates with human tissue in suboptimal wound conditions. We aimed to evaluate these proper...

journal_title：International wound journal

authors： Gowda AU,Chang SM,Chopra K,Matthews JA,Sabino J,Stromberg JA,Zahiri HR,Pinczewski J,Holton LH 3rd,Silverman RP,Singh DP

更新日期：2016-10-01 00:00:00

abstract：:This retrospective study compared the clinical outcomes of negative pressure wound therapy with reticulated open cell foam (NPWT/ROCF) as delivered by Vacuum-Assisted Therapy(®) (V.A.C.(®) Therapy, KCI Licensing Inc., San Antonio, TX) to non-NPWT/ROCF conventional therapy (CT) in split-thickness skin graft (STSG) surv...

journal_title：International wound journal

authors： Blume PA,Key JJ,Thakor P,Thakor S,Sumpio B

更新日期：2010-12-01 00:00:00

abstract：:The use of a rigid disc as a barrier between the wound bed and the wound filler during negative pressure wound therapy (NPWT) has been suggested to prevent damage to exposed organs. However, it is important to determine that the effects of NPWT, such as wound contraction and fluid removal, are maintained during treatm...

journal_title：International wound journal

authors： Anesäter E,Roupé KM,Robertsson P,Borgquist O,Torbrand C,Ingemansson R,Lindstedt S,Malmsjö M

更新日期：2011-08-01 00:00:00

abstract：:Although platelet gel is considered one of the most popular tools in the treatment of chronic ulcers, current consensus on its use is not unanimous. A prospective randomised trial was carried out at the Plastic Surgery Unit of the 'Salvatore Maugeri' Foundation Hospital of Pavia (Italy). The study involved 13 patients...

journal_title：International wound journal

authors： Scevola S,Nicoletti G,Brenta F,Isernia P,Maestri M,Faga A

更新日期：2010-06-01 00:00:00

abstract：:Keloids are fibroproliferative skin disorders characterised clinically by continuous horizontal progression and post-surgical recurrence and histologically by the accumulation of collagen and fibroblast ingredients. Till now, their aetiology remains clear, which may cover genetic, environmental and metabolic factors. ...

journal_title：International wound journal

authors： Huang C,Liu L,You Z,Wang B,Du Y,Ogawa R

更新日期：2017-10-01 00:00:00

abstract：:Diabetic lower extremity wounds cause substantial burden to healthcare systems, costing tens of thousands of dollars per episode. Negative pressure wound therapy (NPWT) devices have been shown to be cost-effective at treating these wounds, but the traditional devices use bulky electrical pumps that require a durable m...

journal_title：International wound journal

authors： Hutton DW,Sheehan P

更新日期：2011-04-01 00:00:00

abstract：:Combinations of various treatment modalities were shown to be more effective than monotherapy when treating hypertrophic scars and keloids. This study was conducted to assess the effectiveness of combination therapy with non-ablative fractional laser and intralesional steroid injection. From May 2015 to June 2017, a t...

journal_title：International wound journal

authors： Shin J,Cho JT,Park SI,Jung SN

更新日期：2019-12-01 00:00:00

abstract：:Indwelling foreign-body infections are a critical medical problem, especially in immunocompromised patients. To examine the pathogenicity of biofilm-forming bacteria settling on foreign materials, mice implanted with plastic discs were infected with Staphylococcus aureus. After opening a wide subcutaneous pocket on th...

journal_title：International wound journal

authors： Makino T,Jimi S,Oyama T,Nakano Y,Hamamoto K,Mamishin K,Yahiro T,Hara S,Takata T,Ohjimi H

更新日期：2015-04-01 00:00:00

abstract：:The aim of this study was to retrospectively evaluate the clinical and culture-positive infection rates of open Gustilo/Anderson type II and III fractures using a protocol nanocrystalline silver wound dressing and hydrosurgical debridement. Retrospective case series through chart review on all type II and III open fra...

journal_title：International wound journal

authors： Keen JS,Desai PP,Smith CS,Suk M

更新日期：2012-02-01 00:00:00