Abstract:
:Combinations of various treatment modalities were shown to be more effective than monotherapy when treating hypertrophic scars and keloids. This study was conducted to assess the effectiveness of combination therapy with non-ablative fractional laser and intralesional steroid injection. From May 2015 to June 2017, a total of 38 patients with hypertrophic scars or keloids were evaluated. The control group of 21 patients received steroid injection alone, and 17 patients (the combined group) received 1550-nm erbium-glass fractional laser treatment and steroid injection simultaneously. The mean number of treatment sessions was statistically fewer in the combined group than in the control group (6.95 vs 5.47, P = .042). There was a significant difference in the patient's scale in the combined group (14.62 vs 22.82, P = .005); however, the observer's scale was not significantly different (17.92 vs 20.55, P = .549). The recurrence rate was 38.1% (8/21) in the control group and 35.3% (6/17) in the combined groups and showed no significant difference (P = .859). However, the mean remission period was statistically longer in the combined group (3.00 months vs 4.17 months, P = .042). Combination therapy with non-ablative fractional laser and intralesional steroid injection showed better results for the treatment of hypertrophic scars and keloids with fewer treatment sessions, better patient satisfaction, and longer remission periods.
journal_name
Int Wound Jjournal_title
International wound journalauthors
Shin J,Cho JT,Park SI,Jung SNdoi
10.1111/iwj.13213subject
Has Abstractpub_date
2019-12-01 00:00:00pages
1450-1456issue
6eissn
1742-4801issn
1742-481Xjournal_volume
16pub_type
杂志文章abstract::Surgical site infections are the most common nosocomial infections in surgical patients. The preventable and the unmodifiable risk factors for deep sternal wound infections (DSWI) have been amply assessed in the literature. The aim of this review was to describe the results of the numerous published studies to describ...
journal_title:International wound journal
pub_type: 杂志文章,评审
doi:10.1111/j.1742-481X.2011.00896.x
更新日期:2012-08-01 00:00:00
abstract::This study aimed to demonstrate the antibacterial effects of bupivacaine and prilocaine on Escherichia coli, Staphylococcus aureus, and Pseudomonas aeruginosa. In our study, the in vitro antimicrobial effects of 20 mg/mL prilocaine and 5 mg/mL bupivacaine were tested against a S. aureus American-type culture collectio...
journal_title:International wound journal
pub_type: 杂志文章
doi:10.1111/iwj.13180
更新日期:2019-10-01 00:00:00
abstract::Surgical patients are at risk of developing a perioperative pressure injury (ORPI) during surgery. Accurate assessment and prompt implementation of prevention strategies or treatment of ORPI are dependent on knowledge and skills of operating room (OR) nurses. The study examined the knowledge and attitude of OR nurses ...
journal_title:International wound journal
pub_type: 杂志文章
doi:10.1111/iwj.13295
更新日期:2020-04-01 00:00:00
abstract::This review and case study report considers the evidence to indicate that the progress of wound healing is negatively affected by the presence of stressors and in circumstances where patients are in pain. It considers the relationship between perceptions of pain, stress and delayed wound healing with a specific focus ...
journal_title:International wound journal
pub_type: 杂志文章,评审
doi:10.1111/j.1742-481X.2012.01038.x
更新日期:2013-12-01 00:00:00
abstract::Non healing diabetic foot ulcers and the resulting potential amputations present significant costs to the health care system and reduce patient quality of life. The goal of diabetic foot ulcer treatment is to obtain wound closure as expeditiously as possible. The use of platelet-rich plasma (PRP) to enhance wound heal...
journal_title:International wound journal
pub_type: 杂志文章,随机对照试验
doi:10.1111/j.1742-481X.2011.00797.x
更新日期:2011-06-01 00:00:00
abstract::Hydrofluoric acid (HF) burns cause immediate damage and painful long-term sequellae. Traditionally, chelating agents have been used as the initial treatment for such burns. We have introduced epidermal growth factor (EGF) into an HF model to compare EGF with Ca(2+) and Mg(2+) treatments; 40 Sprague Dawley rats were di...
journal_title:International wound journal
pub_type: 杂志文章
doi:10.1111/iwj.12214
更新日期:2015-12-01 00:00:00
abstract::Negative pressure wound therapy (NPWT) is considered an effective wound treatment, but there are a number of issues that need to be addressed for improvements to be made. This review aimed to explore the literature relating to the pain and skin trauma that may be experienced during NPWT. A literature search was carrie...
journal_title:International wound journal
pub_type: 杂志文章,评审
doi:10.1111/iwj.12059
更新日期:2015-02-01 00:00:00
abstract::Management of small-bowel fistulas which are in an open abdomen and have no soft tissue overlay or a fistula tract involves many complications and challenges. Controlling the local leakage of enteric contents has a central role in the success of medical treatment. There are several methods to deal with fistula dischar...
journal_title:International wound journal
pub_type: 杂志文章
doi:10.1111/iwj.12726
更新日期:2017-12-01 00:00:00
abstract::Infiltration of surgical wounds with long-acting local anaesthetics (LA) is used to reduce postoperative incisional pain. We hypothesised that infiltration with LA interferes with wound healing in rats. Seventy-two rats were allocated into nine groups. After intraperitoneal anaesthesia, the interscapular dorsal region...
journal_title:International wound journal
pub_type: 杂志文章
doi:10.1111/j.1742-481X.2012.01101.x
更新日期:2014-08-01 00:00:00
abstract::Acellular dermal matrices can successfully heal wounds. This study's goal was to compare clinical outcomes of a novel, open-structure human reticular acellular dermis matrix (HR-ADM) to facilitate wound closure in non-healing diabetic foot ulcers (DFUs) versus DFUs treated with standard of care (SOC). Following a 2-we...
journal_title:International wound journal
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1111/iwj.12600
更新日期:2017-04-01 00:00:00
abstract::Venous leg ulcers are the most common form of non-healing leg ulcers. They are subjected to treatments such as topical medications, dressings, and compression therapies. This can lead to exposure to a number of allergens with subsequent sensitisation and contact dermatitis of the regional skin. This may contribute to ...
journal_title:International wound journal
pub_type: 杂志文章,多中心研究
doi:10.1111/iwj.12905
更新日期:2018-08-01 00:00:00
abstract::Numerous comorbidities and cofactors have been known to influence wound healing processes. In this multicentre study, clinical data of 1 000 patients with chronic leg ulcers from ten specialised dermatological wound care centers were analysed. The patient cohort comprised 567 females and 433 males with an average age ...
journal_title:International wound journal
pub_type: 杂志文章,多中心研究
doi:10.1111/iwj.12387
更新日期:2016-10-01 00:00:00
abstract::Several researches have shown that negative-pressure wound dressings can secure split-thickness skin grafts and improve graft survival. However, in anatomically difficult body regions such as the perineum it is questionable whether these dressings have similar beneficial effects. In this study, we evaluated the effect...
journal_title:International wound journal
pub_type: 杂志文章
doi:10.1111/j.1742-481X.2012.01078.x
更新日期:2014-04-01 00:00:00
abstract::Corticosteroid-induced skin atrophy (CISA) consists of a thinning of the skin and subcutaneous tissues, representing the natural consequence of a prolonged glucocorticosteroids use, both systemic as well as topical. It is characterised by the loss of elasticity and skin thickness, associated with an increased skin fra...
journal_title:International wound journal
pub_type: 杂志文章
doi:10.1111/iwj.13312
更新日期:2020-06-01 00:00:00
abstract::Patients with diabetes mellitus have a lifetime risk of 15% to 25% of developing diabetic foot ulcers (DFUs). DFU is associated with significant morbidity and mortality. Wound imaging systems are useful adjuncts in monitoring of wound progress. Our study aims to review existing literature on the available wound assess...
journal_title:International wound journal
pub_type: 杂志文章
doi:10.1111/iwj.13481
更新日期:2020-12-01 00:00:00
abstract::Diabetic lower extremity wounds cause substantial burden to healthcare systems, costing tens of thousands of dollars per episode. Negative pressure wound therapy (NPWT) devices have been shown to be cost-effective at treating these wounds, but the traditional devices use bulky electrical pumps that require a durable m...
journal_title:International wound journal
pub_type: 杂志文章
doi:10.1111/j.1742-481X.2011.00775.x
更新日期:2011-04-01 00:00:00
abstract::For nearly two decades, Negative Pressure Wound Therapy (NPWT) has been used for temporary wound coverage as well as wound bed preparation. The addition of instillation and dwell time as an adjunct to NPWT (NPWTi-d) enables wound bed cleaning and improved wound bed granulation. Thirty patients with different types of ...
journal_title:International wound journal
pub_type: 杂志文章
doi:10.1111/iwj.13462
更新日期:2020-12-01 00:00:00
abstract::The purpose of the study is to assess the effectiveness of low level laser therapy for wound healing when combined with the Extendicare Wound Prevention and Management Program. Sixteen residents at a Canadian Extendicare nursing home had a total of 27 sites treated consisting of 23 open wounds and 4 'at risk' areas. O...
journal_title:International wound journal
pub_type: 杂志文章
doi:10.1111/j.1742-481X.2008.00491.x
更新日期:2008-06-01 00:00:00
abstract::The aim of this article was to investigate the effectiveness of testing cold immersion recovery responses in the diabetic foot with neuropathy using a contact thermography system based on thermochromic liquid crystals. A total of 81 subjects with no history of diabetic foot ulceration were assigned to neuropathy, non ...
journal_title:International wound journal
pub_type: 杂志文章
doi:10.1111/j.1742-481X.2008.00454.x
更新日期:2008-10-01 00:00:00
abstract::Foot complications cause substantial morbidity in Tanzania, where 70% of leg amputations occur in diabetic patients. The Step by Step Foot Project was initiated to train healthcare personnel in diabetic foot management, facilitate transfer of knowledge and expertise, and improve patient education. The project comprise...
journal_title:International wound journal
pub_type: 杂志文章,多中心研究
doi:10.1111/j.1742-481X.2010.00764.x
更新日期:2011-04-01 00:00:00
abstract::Enzymatic debridement with collagenase is a technique that is commonly used in clinical practice. This systematic review examines the effect of collagenase on all kinds of wounds, compared to an alternative therapy, on wound healing, wound bed characteristics, cost-effectiveness and the occurrence of adverse events. W...
journal_title:International wound journal
pub_type: 杂志文章,meta分析,评审
doi:10.1111/iwj.12760
更新日期:2017-12-01 00:00:00
abstract::Pressure ulcers (PUs) are one of the most prevalent adverse events in acute and chronic care. The root aetiological cause of PUs is sustained cell and tissue deformations, which triggers a synergistic tissue damage cascade that accelerates over relatively short time periods. Changes in skin microclimate conditions are...
journal_title:International wound journal
pub_type: 杂志文章
doi:10.1111/iwj.13309
更新日期:2020-06-01 00:00:00
abstract::Keratin proteins have been shown to play a key role in wound healing. Controlled keratin gene (KRT) expression promotes cell growth, migration and differentiation, and as an example of the importance of keratin proteins, absence of KRT17 has been shown to delay wound closure. In addition, downregulation of KRT6 and KR...
journal_title:International wound journal
pub_type: 杂志文章
doi:10.1111/iwj.12245
更新日期:2016-02-01 00:00:00
abstract::Over the last decade, maggot debridement therapy (MDT) has been recognized by many clinicians as a potential adjunct to conventional therapy, and many patients with non healing, chronic ulcers have been treated. Numerous case reports and case series have described the successful use of MDT in a variety of ulcers. Howe...
journal_title:International wound journal
pub_type: 杂志文章,评审
doi:10.1111/j.1742-481X.2011.00919.x
更新日期:2012-10-01 00:00:00
abstract::Covering the reconstructed area with a healthy soft-tissue envelope is a major challenge after limb-sparing surgery in patients with malignant bone and soft-tissue tumours. Negative pressure wound therapy (NPWT) of open wounds hastens healing and minimises the requirement for complex reconstructive soft-tissue surgery...
journal_title:International wound journal
pub_type: 杂志文章
doi:10.1111/iwj.12318
更新日期:2016-06-01 00:00:00
abstract::Cushing's syndrome is a condition caused by high levels of glucocorticoids, or most commonly as a result of prolonged exposure to exogenous steroids. Clinical features include diabetes, hypertension, obesity, skin atrophy, immune suppression and delayed wound healing. We report a patient with iatrogenic Cushing's synd...
journal_title:International wound journal
pub_type: 杂志文章
doi:10.1111/j.1742-481X.2010.00746.x
更新日期:2011-02-01 00:00:00
abstract:BACKGROUND:This study was designed to elucidate the in vivo efficacy of epidermal growth factor (EGF) on wound healing in non diabetic and diabetic rats. METHODS:Ninety-six male Wistar-Albino rats were randomly divided into six groups. Saline-moistened gauze, pure gelatin or EGF in gelatin-microsphere dressings were u...
journal_title:International wound journal
pub_type: 杂志文章
doi:10.1111/j.1742-481X.2009.00584.x
更新日期:2009-04-01 00:00:00
abstract::Current embodiments of negative pressure wound therapy (NPWT) create a hermetically sealed chamber at the surface of the body using polyurethane foam connected to a vacuum pump, which is then covered by a flexible adhesive drape. Commercially available NPWT systems routinely use flexible polyethylene films that have a...
journal_title:International wound journal
pub_type: 杂志文章
doi:10.1111/iwj.12589
更新日期:2017-02-01 00:00:00
abstract::The initial care of burn wounds and choice of dressing are pivotal to optimally support the healing process. To ensure fast re-epithelialisation within 10-14 days and prevent complications, an optimal healing environment is essential. An innovative dressing based on nanocellulose was used for the treatment of burns in...
journal_title:International wound journal
pub_type: 杂志文章
doi:10.1111/iwj.13548
更新日期:2021-01-19 00:00:00
abstract::Keloids are fibroproliferative skin disorders characterised clinically by continuous horizontal progression and post-surgical recurrence and histologically by the accumulation of collagen and fibroblast ingredients. Till now, their aetiology remains clear, which may cover genetic, environmental and metabolic factors. ...
journal_title:International wound journal
pub_type: 杂志文章
doi:10.1111/iwj.12693
更新日期:2017-10-01 00:00:00