Abstract：
:This study aimed to demonstrate the antibacterial effects of bupivacaine and prilocaine on Escherichia coli, Staphylococcus aureus, and Pseudomonas aeruginosa. In our study, the in vitro antimicrobial effects of 20 mg/mL prilocaine and 5 mg/mL bupivacaine were tested against a S. aureus American-type culture collection (ATCC) 29213, P. aeruginosa ATCC 27853, and E. coli ATCC 25922, divided into Group P (Prilocaine) and Group B (Bupivacaine), respectively. S. aureus ATCC 29213, P. aeruginosa ATCC 27853, and E. coli ATCC 25922 were cultured on Mueller Hinton agar (Oxoid, Basingstoke, UK) plates for 18 to 24 hours at 37°C. In terms of inhibition zone diameters, inhibition of S. aureus ATCC 29213 was observed in both groups at the 12th and 24th hours. The 12th- and 24th-hour S. aureus ATCC 29213 value was significantly higher in Group P compared with Group B (P = .008). At the 12th and 24th hours, inhibition of E. coli ATCC 25922 was observed in both groups. The 12th- and 24th-hour E. coli ATCC 25922 value was significantly higher in Group P compared with Group B (P = .008). In our study, it was seen that prilocaine and bupivacaine had an antimicrobial effect on S. aureus and E. coli. In the comparison between these two local anesthetics (LAs), this effect was found to be significantly higher in prilocaine than bupivacaine. Therefore, we are of the opinion that antimicrobial effect potentials should also be taken into account in the selection of an LA agent in order to prevent the complications of an infection that might develop during LA infiltration and might lead to serious morbidity.
journal_name
Int Wound Jjournal_title
International wound journalauthors
Kesici S,Demirci M,Kesici Udoi
10.1111/iwj.13180subject
Has Abstractpub_date
2019-10-01 00:00:00pages
1185-1189issue
5eissn
1742-4801issn
1742-481Xjournal_volume
16pub_type
杂志文章abstract：:This prospective, non comparative study evaluated the safety and effectiveness of an adhesive gelling foam dressing in pressure ulcer management. Twenty-three subjects with exuding pressure ulcers were recruited from seven centres in the USA and Canada. Study treatment included an adhesive gelling foam dressing, optio...
journal_title：International wound journal
pub_type： 临床试验,杂志文章,多中心研究
doi：10.1111/j.1742-481X.2007.00428.x
更新日期：2008-03-01 00:00:00
abstract：:Wound bed preparation (WBP) is an integral part of the care programme for chronic wounds. The acronym TIME is used in the context of WBP and describes four barriers to healing in chronic wounds; namely, dead Tissue, Infection and inflammation, Moisture imbalance and a non-migrating Edge. Larval debridement therapy (LD...
journal_title：International wound journal
pub_type： 杂志文章,评审
doi：10.1111/iwj.12457
更新日期：2016-08-01 00:00:00
abstract：:Iodine-based products are antibacterial. The small iodine molecular size is ideally suited to treat surface critical colonisation. Inadine is a 10% povidone iodine dressing with the equivalent of 1% available iodine that is easily extracted from the viscose backing by serum or exudate. The use of hydrophilic polyethyl...
journal_title：International wound journal
pub_type： 杂志文章
doi：10.1111/iwj.12602
更新日期：2017-04-01 00:00:00
abstract：:Foreign modelling agent reactions (FMAR) are the result of the injection of unapproved high-viscosity fluids with the purpose of cosmetic body modelling. Its consequences lead to ulceration, disfigurement and even death, and it has reached epidemic proportions in several regions of the world. We describe a series of p...
journal_title：International wound journal
pub_type： 杂志文章,评审
doi：10.1111/iwj.12643
更新日期：2017-06-01 00:00:00
abstract：:Negative pressure wound therapy (NPWT) contracts the wound and alters the pressure in the tissue of the wound edge, which accelerates wound healing. The aim of this study was to examine the effect of the type (foam or gauze) and size (small or large) of wound filler for NPWT on wound contraction and tissue pressure. N...
journal_title：International wound journal
pub_type： 杂志文章
doi：10.1111/j.1742-481X.2011.00790.x
更新日期：2011-08-01 00:00:00
abstract：:The aim of this systematic review was to determine the supporting evidence for the clinical use of hydrogel dressings as a first aid measure for burn wound management in the pre-hospital setting. Two authors searched three databases (Ovid Medline, Ovid Embase and The Cochrane Library) for relevant English language art...
journal_title：International wound journal
pub_type： 杂志文章,评审
doi：10.1111/iwj.12469
更新日期：2016-08-01 00:00:00
abstract：:An understanding of risk factors associated with mortality among pressure ulcer patients can inform prognostic counselling and treatment plans. This retrospective cohort study examined associations of comorbid illness, demographic characteristics and laboratory values with 90-day and 90- to 180-day mortality in adult ...
journal_title：International wound journal
pub_type： 杂志文章
doi：10.1111/j.1742-481X.2012.01032.x
更新日期：2014-02-01 00:00:00
abstract：:Health care-associated infections in hospitals, including surgical site infections, contribute significantly to morbidity as well as mortality. Surgical incision management (SIM) using negative pressure wound therapy (Prevena™ Incision Management System, Kinetic Concepts, Inc., San Antonio, TX, USA) is designed to cov...
journal_title：International wound journal
pub_type： 杂志文章
doi：10.1111/iwj.12261
更新日期：2014-06-01 00:00:00
abstract：:Breast cancer is a serious disease in women. We estimated the global technical success rate and complication rates of percutaneous vacuum-assisted breast biopsy (VABB). PubMed, Embase, Web of Science, and Scopus databases were retrieved up to July 2018 to find studies in which technical success rate and complication r...
journal_title：International wound journal
pub_type： 杂志文章,meta分析
doi：10.1111/iwj.13224
更新日期：2019-12-01 00:00:00
abstract：:We demonstrate sodium pyruvate (NaPy) pre-treatment as a successful approach for pressure ulcer (PU) prevention by averting their aetiological origin-cell-level damage and death by large, sustained mechanical loads. We evaluated the NaPy pre-treatment effect on permeability changes in the cell's plasma membrane (PM) f...
journal_title：International wound journal
pub_type： 杂志文章
doi：10.1111/iwj.13173
更新日期：2019-10-01 00:00:00
abstract：:Immunosuppressive therapy is increasingly being used in clinical practice and has been shown to affect wound healing to varying degrees. This article looks at the effects of the newer immunosuppressive agents on wound healing. It is shown that wound healing is impaired via different mechanisms. Some of the animal and ...
journal_title：International wound journal
pub_type： 杂志文章,评审
doi：10.1111/j.1742-481X.2012.00950.x
更新日期：2013-02-01 00:00:00
abstract：:Surgical site infections are the most common nosocomial infections in surgical patients. The preventable and the unmodifiable risk factors for deep sternal wound infections (DSWI) have been amply assessed in the literature. The aim of this review was to describe the results of the numerous published studies to describ...
journal_title：International wound journal
pub_type： 杂志文章,评审
doi：10.1111/j.1742-481X.2011.00896.x
更新日期：2012-08-01 00:00:00
abstract：:Management of small-bowel fistulas which are in an open abdomen and have no soft tissue overlay or a fistula tract involves many complications and challenges. Controlling the local leakage of enteric contents has a central role in the success of medical treatment. There are several methods to deal with fistula dischar...
journal_title：International wound journal
pub_type： 杂志文章
doi：10.1111/iwj.12726
更新日期：2017-12-01 00:00:00
abstract：:This study developed a measuring instrument of pressure-injury risk assessment competence for nursing education adopting theoretical procedures based on competence structuration to support the psychometric quality. The objective of this study is testing the psychometric properties of the instrument using simulation st...
journal_title：International wound journal
pub_type： 杂志文章
doi：10.1111/iwj.13311
更新日期：2020-06-01 00:00:00
abstract：:The aims of this randomised controlled study were to determine whether the application of silicone adhesive dressings with standard preventive care would reduce the impairment of skin integrity and to evaluate the subepidermal moisture (SEM) value in anatomical locations to predict impairment of skin integrity. Of the...
journal_title：International wound journal
pub_type： 杂志文章,随机对照试验
doi：10.1111/iwj.13028
更新日期：2019-03-01 00:00:00
abstract：:Silver nanoparticles are gaining importance as an antimicrobial agent in wound dressings. Chitin is a biopolymer envisioned to promote rapid dermal regeneration and accelerate wound healing. This study was focused on the evaluation of chitin membranes containing silver nanoparticles for use as an antimicrobial wound d...
journal_title：International wound journal
pub_type： 杂志文章
doi：10.1111/j.1742-481X.2012.01084.x
更新日期：2014-06-01 00:00:00
abstract：:Indwelling foreign-body infections are a critical medical problem, especially in immunocompromised patients. To examine the pathogenicity of biofilm-forming bacteria settling on foreign materials, mice implanted with plastic discs were infected with Staphylococcus aureus. After opening a wide subcutaneous pocket on th...
journal_title：International wound journal
pub_type： 杂志文章
doi：10.1111/iwj.12061
更新日期：2015-04-01 00:00:00
abstract：:We evaluated the efficacy and safety of a povidone-iodine (PVP-I) foam dressing (Betafoam) for donor site dressing versus a hydrocellular foam dressing (Allevyn) and petrolatum gauze. This prospective Phase 4 study was conducted between March 2016 and April 2017 at eight sites in Korea. A total of 106 consenting patie...
journal_title：International wound journal
pub_type： 杂志文章
doi：10.1111/iwj.13043
更新日期：2019-04-01 00:00:00
abstract：:Reducing and preventing postoperative pain are currently a topic of great interest. There are different modalities for providing analgesia that can provide an alternative or adjunct to opioid therapy. One mode of therapy involves the use of portable pain pump devices that can deliver continuous local anaesthesia direc...
journal_title：International wound journal
pub_type： 杂志文章
doi：10.1111/j.1742-481X.2010.00675.x
更新日期：2010-06-01 00:00:00
abstract：:To describe the steps needed for a successful implementation of an e-health programme (the Mobile Wound Care system) in rural Victoria, Australia and to provide recommendations for future e-health initiatives. Wound care is a major burden on the health care system. Optimal wound care was found to be impeded by issues ...
journal_title：International wound journal
pub_type： 杂志文章
doi：10.1111/iwj.12041
更新日期：2014-06-01 00:00:00
abstract：:A 6-month-old Caucasian baby is described with a postaxial polydactyly of the letf foot. Radiographic examination revealed the accessory digit was composed of soft tissue, some with a tiny osseous element, originated from around the metatarsophalangeal joint, defined by floating type (FT). The parents had consistent d...
journal_title：International wound journal
pub_type： 杂志文章
doi：10.1111/iwj.12700
更新日期：2017-10-01 00:00:00
abstract：:This review and case study report considers the evidence to indicate that the progress of wound healing is negatively affected by the presence of stressors and in circumstances where patients are in pain. It considers the relationship between perceptions of pain, stress and delayed wound healing with a specific focus ...
journal_title：International wound journal
pub_type： 杂志文章,评审
doi：10.1111/j.1742-481X.2012.01038.x
更新日期：2013-12-01 00:00:00
abstract：:Skin grafting is one of the most common surgical procedures in the area of non-healing wounds by which skin or a skin substitute is placed over a wound to replace and regenerate the damaged skin. Chronic leg ulcers are an important problem and a major source of expense for Western countries and for which many differen...
journal_title：International wound journal
pub_type： 杂志文章,评审
doi：10.1111/iwj.12575
更新日期：2017-02-01 00:00:00
abstract：:The initial care of burn wounds and choice of dressing are pivotal to optimally support the healing process. To ensure fast re-epithelialisation within 10-14 days and prevent complications, an optimal healing environment is essential. An innovative dressing based on nanocellulose was used for the treatment of burns in...
journal_title：International wound journal
pub_type： 杂志文章
doi：10.1111/iwj.13548
更新日期：2021-01-19 00:00:00
abstract：:This data review reports the results of 15 patients who were treated with Vacuum-Assisted Closure (VAC) negative pressure therapy system in addition to the timed, intermittent delivery of an instilled topical solution for management of their complex, infected wounds. Prospective data for 15 patients treated with negat...
journal_title：International wound journal
pub_type： 杂志文章
doi：10.1111/j.1742-481X.2007.00423.x
更新日期：2008-06-01 00:00:00
abstract：:Wound chronification and opportunistic infections stand as major factors leading to lower extremities amputations in diabetes. The molecular mechanisms underlying diabetic's torpid healing have not been elucidated. We present the case of a female diabetic patient that after a plantar abscess surgical drainage, tight g...
journal_title：International wound journal
pub_type： 杂志文章
doi：10.1111/j.1742-481X.2012.12000.x
更新日期：2013-04-01 00:00:00
abstract：:Pressure injuries are one of the most common and costly complications occurring in US hospitals. With up to 3 million patients affected each year, hospital-acquired pressure injuries (HAPIs) place a substantial burden on the US healthcare system. In the current study, US hospital discharge records from 9.6 million pat...
journal_title：International wound journal
pub_type： 杂志文章
doi：10.1111/iwj.13482
更新日期：2020-12-01 00:00:00
abstract：:Major sickle cell disease syndrome (SCD) is a set of potentially serious and disabling constitutional haemoglobin pathologies characterised by chronic haemolysis and vaso-occlusion phenomena. If expression takes the form of acute vaso-occlusive crisis, SCD is currently considered to be a chronic systemic pathology, pr...
journal_title：International wound journal
pub_type： 杂志文章
doi：10.1111/iwj.13115
更新日期：2019-08-01 00:00:00
abstract：:The Smart Negative Pressure (SNaP) wound care system is a novel device that is single-patient use, ultra-portable, and light weight and does not rely on battery or need recharging. A systematic search was performed on major databases to identify relevant articles including case reports, retrospective case series, and ...
journal_title：International wound journal
pub_type： 杂志文章
doi：10.1111/iwj.13114
更新日期：2019-08-01 00:00:00
abstract：:Senescent fibroblasts, which are present in chronic ulcers, are the reason for the wound becoming chronic. In this study, we introduce full-thickness micro skin grafts in the ulcer, a surgical technique known as a 'nested graft', which gave encouraging results leading to complete wound healing in all patients. The ass...
journal_title：International wound journal
pub_type： 杂志文章,评审
doi：10.1111/iwj.12415
更新日期：2016-12-01 00:00:00
