Abstract:
:We evaluated the efficacy and safety of a povidone-iodine (PVP-I) foam dressing (Betafoam) for donor site dressing versus a hydrocellular foam dressing (Allevyn) and petrolatum gauze. This prospective Phase 4 study was conducted between March 2016 and April 2017 at eight sites in Korea. A total of 106 consenting patients (aged ≥ 19 years, scheduled for split-thickness skin graft) were randomised 1:1:1 to PVP-I foam, hydrocellular, or petrolatum gauze dressings for up to 28 days after donor site collection. We assessed time to complete epithelialisation, proportion with complete epithelialisation at Day 14, and wound infection. Epithelialisation time was the shortest with PVP-I foam dressing (12.74 ± 3.51 days) versus hydrocellular foam dressing (16.61 ± 4.45 days; P = 0.0003) and petrolatum gauze (15.06 ± 4.26 days, P = 0.0205). At Day 14, 83.87% of PVP-I foam dressing donor sites had complete epithelialisation, versus 36.36% of hydrocellular foam dressing donor sites (P = 0.0001) and 55.88% of petrolatum gauze donor sites (P = 0.0146). There were no wound infections. Incidence rates of adverse events were comparable across groups (P = 0.1940). PVP-I foam dressing required less time to complete epithelialisation and had a good safety profile.
journal_name
Int Wound Jjournal_title
International wound journalauthors
Pak CS,Park DH,Oh TS,Lee WJ,Jun YJ,Lee KA,Oh KS,Kwak KH,Rhie JWdoi
10.1111/iwj.13043subject
Has Abstractpub_date
2019-04-01 00:00:00pages
379-386issue
2eissn
1742-4801issn
1742-481Xjournal_volume
16pub_type
杂志文章abstract::The aims of this randomised controlled study were to determine whether the application of silicone adhesive dressings with standard preventive care would reduce the impairment of skin integrity and to evaluate the subepidermal moisture (SEM) value in anatomical locations to predict impairment of skin integrity. Of the...
journal_title:International wound journal
pub_type: 杂志文章,随机对照试验
doi:10.1111/iwj.13028
更新日期:2019-03-01 00:00:00
abstract::Wound dehiscence is a surgical complication caused by the application of opposing and distracting forces tending to pull apart the suture line. In recent years, a novel negative pressure surgical management system has been developed to prevent surgical wound complications. This system creates a closed environment that...
journal_title:International wound journal
pub_type: 杂志文章
doi:10.1111/iwj.12040
更新日期:2015-02-01 00:00:00
abstract::Senescent fibroblasts, which are present in chronic ulcers, are the reason for the wound becoming chronic. In this study, we introduce full-thickness micro skin grafts in the ulcer, a surgical technique known as a 'nested graft', which gave encouraging results leading to complete wound healing in all patients. The ass...
journal_title:International wound journal
pub_type: 杂志文章,评审
doi:10.1111/iwj.12415
更新日期:2016-12-01 00:00:00
abstract::Wide and deep wound defects are a challenge to surgeons, particularly when aggressive or more radical operations are unavailable. This article introduces refined techniques, indications and the clinical experience of the application of negative pressure wound therapy (NPWT) as an easy ancillary wound dressing method f...
journal_title:International wound journal
pub_type: 杂志文章
doi:10.1111/j.1742-481X.2011.00813.x
更新日期:2011-08-01 00:00:00
abstract::The initial care of burn wounds and choice of dressing are pivotal to optimally support the healing process. To ensure fast re-epithelialisation within 10-14 days and prevent complications, an optimal healing environment is essential. An innovative dressing based on nanocellulose was used for the treatment of burns in...
journal_title:International wound journal
pub_type: 杂志文章
doi:10.1111/iwj.13548
更新日期:2021-01-19 00:00:00
abstract::Mohs micrographic surgery is the best therapeutical option for hand squamous cell carcinoma without bone involvement; however, the reconstruction of the surgical defect could be very difficult if the tumour is located in the distal phalanx of a finger. We present the case of a patient with a squamous cell carcinoma of...
journal_title:International wound journal
pub_type:
doi:10.1111/iwj.12979
更新日期:2019-06-01 00:00:00
abstract::Enzymatic debridement with collagenase is a technique that is commonly used in clinical practice. This systematic review examines the effect of collagenase on all kinds of wounds, compared to an alternative therapy, on wound healing, wound bed characteristics, cost-effectiveness and the occurrence of adverse events. W...
journal_title:International wound journal
pub_type: 杂志文章,meta分析,评审
doi:10.1111/iwj.12760
更新日期:2017-12-01 00:00:00
abstract::In May 2011, an international panel of wound care experts from multiple disciplines convened to develop this document to summarise the evolution of negative pressure wound therapy (NPWT) technology devices over the past 15 years, specifically concentrating on the V.A.C.(®) Therapy (KCI USA, Inc., San Antonio, TX) fam...
journal_title:International wound journal
pub_type:
doi:10.1111/j.1742-481X.2012.00978.x
更新日期:2012-08-01 00:00:00
abstract::Chronic wounds, including diabetic foot ulcers, pressure ulcers and venous leg ulcers, represent a significant cause of morbidity in developed countries, predominantly in older patients. The aetiology of these wounds is probably multifactorial, but the role of bacteria in their pathogenesis is still unclear. Moreover,...
journal_title:International wound journal
pub_type: 杂志文章
doi:10.1111/j.1742-481X.2011.00910.x
更新日期:2012-10-01 00:00:00
abstract::The aim of this study was to investigate the relationship between perioperative corticosteroids administration and the incidence of pressure ulcers (PUs) in cardiovascular surgical patients. A retrospective analysis was performed on data from consecutive patients who had cardiac surgery in 2012. Univariate and multiva...
journal_title:International wound journal
pub_type: 杂志文章
doi:10.1111/iwj.12168
更新日期:2015-10-01 00:00:00
abstract::The World Health Assembly declared 2020, the International Year of the Nurse and the Midwife. Recent editorials and commentaries support the leading role of nurses and midwives as frontline caregivers emphasizing the need to invest in the nursing workforce worldwide to meet global health needs. Today nurses are also l...
journal_title:International wound journal
pub_type: 杂志文章
doi:10.1111/iwj.13492
更新日期:2020-12-01 00:00:00
abstract::It has been shown that pressure ulcer formation in critically ill paediatric patients increases morbidity and mortality. We sought to identify factors associated with pressure ulcer formation in paediatric patients on extracorporeal membrane oxygenation (ECMO). From December 2014 to 2015, we identified patients at our...
journal_title:International wound journal
pub_type: 杂志文章
doi:10.1111/iwj.13049
更新日期:2019-04-01 00:00:00
abstract::Chronic wounds are a significant problem in Australia. The health care-related costs of chronic wounds in Australia are considerable, equivalent to more than AUD $3.5 billion, approximately 2% of national health care expenditure. Chronic wounds can also have a significant negative impact on the health-related quality ...
journal_title:International wound journal
pub_type: 杂志文章
doi:10.1111/iwj.12996
更新日期:2019-02-01 00:00:00
abstract::The purpose of this study was to determine the relationship between the scores of Braden scale and pressure ulcer development among critically ill patients. All patients who admitted to intensive care unit (ICU) in 3 months (during July-October 2010) were surveyed with Braden scale. Patients who gained higher score of...
journal_title:International wound journal
pub_type: 杂志文章
doi:10.1111/j.1742-481X.2011.00852.x
更新日期:2012-06-01 00:00:00
abstract::Current embodiments of negative pressure wound therapy (NPWT) create a hermetically sealed chamber at the surface of the body using polyurethane foam connected to a vacuum pump, which is then covered by a flexible adhesive drape. Commercially available NPWT systems routinely use flexible polyethylene films that have a...
journal_title:International wound journal
pub_type: 杂志文章
doi:10.1111/iwj.12589
更新日期:2017-02-01 00:00:00
abstract::Although chronic wounds have a high socio-economic impact, data on comparative effectiveness of treatments are rare. UrgoStart(®) is a hydroactive dressing containing a nano-oligosaccharide factor (NOSF). This study aimed at evaluating the cost-effectiveness of this NOSF-containing wound dressing in vascular leg ulcer...
journal_title:International wound journal
pub_type: 杂志文章
doi:10.1111/iwj.12238
更新日期:2016-02-01 00:00:00
abstract::The aim of this study was to determine the prevalence, severity, location, aetiology, treatment and healing of medical device-related pressure ulcers (PUs) in intensive care patients for up to 7 days. A prospective repeated measures study design was used. Patients in six intensive care units of two major medical centr...
journal_title:International wound journal
pub_type: 杂志文章
doi:10.1111/iwj.12026
更新日期:2014-12-01 00:00:00
abstract::The aim of the present study was to evaluate the efficacy of a new product (Neuropad repair foam(®)) in promoting skin hydration of the foot in type 2 diabetes. Included in this study were 20 type 2 diabetic patients (10 men, mean age 61·40 ± 2·44 years). Patients applied Neuropad repair foam(®) on the plantar aspect ...
journal_title:International wound journal
pub_type: 杂志文章
doi:10.1111/j.1742-481X.2011.00786.x
更新日期:2011-06-01 00:00:00
abstract::Previous studies have reported that the use of incisional negative pressure wound therapy (INPWT) might reduce the incidence of wound infections, although its mechanism remains unknown. We designed a prospective study to explore the effects of INPWT on different stages of the wound healing process. After meeting the i...
journal_title:International wound journal
pub_type: 杂志文章
doi:10.1111/iwj.13497
更新日期:2020-11-25 00:00:00
abstract::Globally, wound care costs the health care system 2-3% of the total expenditure on health, which equates to several billion dollars annually. To date, there are little data on the cost and healing rates of various wounds. This has been partly because of the difficulty in tracking wound management as the majority of wo...
journal_title:International wound journal
pub_type: 杂志文章
doi:10.1111/iwj.12414
更新日期:2016-10-01 00:00:00
abstract::This prospective, non comparative study evaluated the safety and effectiveness of an adhesive gelling foam dressing in pressure ulcer management. Twenty-three subjects with exuding pressure ulcers were recruited from seven centres in the USA and Canada. Study treatment included an adhesive gelling foam dressing, optio...
journal_title:International wound journal
pub_type: 临床试验,杂志文章,多中心研究
doi:10.1111/j.1742-481X.2007.00428.x
更新日期:2008-03-01 00:00:00
abstract::The aim of the study was to evaluate the maintenance of the 30° side-lying lateral tilt position among aged care residents at the risk of developing pressure injuries when using the standard care pillow and a purpose-designed positioning device. An observational study was conducted. Participants were monitored during ...
journal_title:International wound journal
pub_type: 杂志文章
doi:10.1111/iwj.13142
更新日期:2019-10-01 00:00:00
abstract::Wound chronification and opportunistic infections stand as major factors leading to lower extremities amputations in diabetes. The molecular mechanisms underlying diabetic's torpid healing have not been elucidated. We present the case of a female diabetic patient that after a plantar abscess surgical drainage, tight g...
journal_title:International wound journal
pub_type: 杂志文章
doi:10.1111/j.1742-481X.2012.12000.x
更新日期:2013-04-01 00:00:00
abstract::The purpose of this project was to evaluate associations of increasing diabetic foot surgery stage with postoperative outcome. This project, designed as a retrospective cohort model, was conducted at three large, urban referral-based diabetic foot clinics. The investigators abstracted medical records from 180 patients...
journal_title:International wound journal
pub_type: 杂志文章,多中心研究
doi:10.1111/j.1742-481X.2006.00236.x
更新日期:2006-09-01 00:00:00
abstract::Pressure injuries are key clinical indicators of care standard. In Australia, pressure injuries increase length of hospital stay by 4.31 and cost $285 million annually. This pilot study examined the effectiveness of sacral dressing in reducing the prevalence of pressure injuries in older, high-risk patients. A non ran...
journal_title:International wound journal
pub_type: 临床试验,杂志文章
doi:10.1111/j.1742-481X.2012.01025.x
更新日期:2013-10-01 00:00:00
abstract::Wound healing is a complex cellular and biochemical process and can be affected by several systemic and local factors. In this study, we aimed to discuss the aetiologic factors of non-healing wounds and the management of this complicated process with current information. The medical data of the patients who were admit...
journal_title:International wound journal
pub_type: 杂志文章
doi:10.1111/iwj.13292
更新日期:2020-04-01 00:00:00
abstract::Infiltration of surgical wounds with long-acting local anaesthetics (LA) is used to reduce postoperative incisional pain. We hypothesised that infiltration with LA interferes with wound healing in rats. Seventy-two rats were allocated into nine groups. After intraperitoneal anaesthesia, the interscapular dorsal region...
journal_title:International wound journal
pub_type: 杂志文章
doi:10.1111/j.1742-481X.2012.01101.x
更新日期:2014-08-01 00:00:00
abstract::Wound clinics are seeing an increase in the number of 'complex' wounds, which arise as the result of the interaction between multiple coexisting systemic pathologies, environmental factors and local wound factors. These complex wounds require an approach to diagnosis and management that can encapsulate all these facto...
journal_title:International wound journal
pub_type: 杂志文章,评审
doi:10.1111/j.1742-481X.2007.00329.x
更新日期:2007-06-01 00:00:00
abstract::This study sought to both assist in the selection of flaps for ischial pressure wound re-construction and to evaluate the overall complication rates associated with re-construction. A retrospective medical record review was conducted for 78 patients following the surgical re-construction of an ischial pressure sore. R...
journal_title:International wound journal
pub_type: 杂志文章
doi:10.1111/j.1742-481X.2010.00662.x
更新日期:2010-04-01 00:00:00
abstract::Randomised clinical trials (RCTs) to evaluate diabetic foot wound therapies have systematically eliminated large acute wounds from evaluation, focusing only on smaller chronic wounds. The purpose of this study was to evaluate the proportion and rate of wound healing in acute and chronic wounds after partial foot amput...
journal_title:International wound journal
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1111/j.1742-481X.2006.00270.x
更新日期:2007-03-01 00:00:00