Expression of cell proliferation cycle negative regulators in fibroblasts of an ischemic diabetic foot ulcer. A clinical case report.

abstract：:This review and case study report considers the evidence to indicate that the progress of wound healing is negatively affected by the presence of stressors and in circumstances where patients are in pain. It considers the relationship between perceptions of pain, stress and delayed wound healing with a specific focus ...

journal_title：International wound journal

authors： Matsuzaki K,Upton D

更新日期：2013-12-01 00:00:00

abstract：:For nearly two decades, Negative Pressure Wound Therapy (NPWT) has been used for temporary wound coverage as well as wound bed preparation. The addition of instillation and dwell time as an adjunct to NPWT (NPWTi-d) enables wound bed cleaning and improved wound bed granulation. Thirty patients with different types of ...

journal_title：International wound journal

authors： Diehm YF,Loew J,Will PA,Fischer S,Hundeshagen G,Ziegler B,Gazyakan E,Kneser U,Hirche C

更新日期：2020-12-01 00:00:00

abstract：:We report a 53-year-old farmer who developed subcutaneous and cerebral masses 24 years after penetrating trauma during a tropic storm. Computed tomography scans, magnetic resonance imaging and histopathology disclosed actinomycetoma, a disease that rarely develops after trauma and is only occasionally seen with intrac...

journal_title：International wound journal

authors： Verma SB,Nayak S,Pasale RK,Kittner T,Wollina U

更新日期：2008-12-01 00:00:00

abstract：:Chronic non-healing wounds are a burden in the Long-Term Care (LTC) sector, increasing costs, morbidity, and mortality and causing pain and suffering. The objective of this LTC Innovation pilot was to test the value of a promising new neuromuscular stimulation device in elevating the experience and satisfaction of the...

journal_title：International wound journal

authors： Harris C,Ramage D,Boloorchi A,Vaughan L,Kuilder G,Rakas S

更新日期：2019-02-01 00:00:00

abstract：:Mohs micrographic surgery is the best therapeutical option for hand squamous cell carcinoma without bone involvement; however, the reconstruction of the surgical defect could be very difficult if the tumour is located in the distal phalanx of a finger. We present the case of a patient with a squamous cell carcinoma of...

journal_title：International wound journal

authors： Magliano J,Rossi V,Turra N,Bazzano C

更新日期：2019-06-01 00:00:00

abstract：:Randomised clinical trials (RCTs) to evaluate diabetic foot wound therapies have systematically eliminated large acute wounds from evaluation, focusing only on smaller chronic wounds. The purpose of this study was to evaluate the proportion and rate of wound healing in acute and chronic wounds after partial foot amput...

journal_title：International wound journal

authors： Armstrong DG,Lavery LA,Boulton AJ

更新日期：2007-03-01 00:00:00

abstract：:Chronic wounds are a growing challenge for physicians and health insurance agencies. The burden of affected patients is enormous, because of pain but also because of long-lasting therapies and dependence on nursing services. In other areas of medicine, computer-based diagnostics is established, yet, accurate wound doc...

journal_title：International wound journal

authors： Stremitzer S,Wild T,Hoelzenbein T

更新日期：2007-06-01 00:00:00

abstract：:Nicorandil, a nicotinamide ester, was first reported to be involved in the induction of oral ulcers in 1997. Since then, many reports of single or multiple nicorandil-induced ulcerations (NIUs) have been reported. We hypothesised that in the case of high-dosage nicorandil or after an increased dosage of nicorandil, ni...

journal_title：International wound journal

authors： Trechot P,Jouzeau JY,Brouillard C,Scala-Bertola J,Petitpain N,Cuny JF,Gauchotte G,Schmutz JL,Barbaud A

更新日期：2015-10-01 00:00:00

abstract：:Negative pressure wound therapy (NPWT) is an established method for the faster wound healing of chronic non-healing wounds. It is also used for laparostomy wounds and healing of split skin grafts. The commercially available machine and the consumables for NPWT are very expensive and economically not feasible in develo...

journal_title：International wound journal

authors： Gopal SV,Solomon A

更新日期：2019-02-01 00:00:00

abstract：:Pressure ulcers (PUs) are one of the most prevalent adverse events in acute and chronic care. The root aetiological cause of PUs is sustained cell and tissue deformations, which triggers a synergistic tissue damage cascade that accelerates over relatively short time periods. Changes in skin microclimate conditions are...

journal_title：International wound journal

authors： Schwartz D,Gefen A

更新日期：2020-06-01 00:00:00

abstract：:Ulcers in radiated skin continue to be a challenge for health care practitioners. Healing impairment in the setting of radiation-damaged tissue will most of the time lead to chronic wounds that reduce the patient's quality of life. In this review, we present an update of the pathophysiology of tissue damage caused by ...

journal_title：International wound journal

authors： Olascoaga A,Vilar-Compte D,Poitevin-Chacón A,Contreras-Ruiz J

更新日期：2008-06-01 00:00:00

abstract：:Marjolin's ulcer refers to malignant degeneration in a chronic wound. Although originally described in an area of burns scar, many other chronic wounds such as osteomyelitis sinus tracts, venous stasis ulcers and chronic pressure sores have the potential to undergo malignant transformation. We present an interesting c...

journal_title：International wound journal

authors： Fairbairn NG,Hamilton SA

更新日期：2011-10-01 00:00:00

abstract：:This is a prospective study with the aim to determine specific patterns of burn wound bacterial colonisation and antimicrobial resistance profiles. There is a high incidence of infections and septicaemia in post-burn patients, which, in turn, are associated with high morbidity and mortality, a fact that compelled us t...

journal_title：International wound journal

authors： Mir MA,Khurram MF,Khan AH

更新日期：2017-02-01 00:00:00

abstract：:Keloids are fibroproliferative skin disorders characterised clinically by continuous horizontal progression and post-surgical recurrence and histologically by the accumulation of collagen and fibroblast ingredients. Till now, their aetiology remains clear, which may cover genetic, environmental and metabolic factors. ...

journal_title：International wound journal

authors： Huang C,Liu L,You Z,Wang B,Du Y,Ogawa R

更新日期：2017-10-01 00:00:00

abstract：:Biological alternatives to synthetic meshes are increasingly utilised in complex abdominal wall reconstruction. There is a lack of evidence demonstrating that non-cross-linked porcine acellular dermal matrix vascularizes and integrates with human tissue in suboptimal wound conditions. We aimed to evaluate these proper...

journal_title：International wound journal

authors： Gowda AU,Chang SM,Chopra K,Matthews JA,Sabino J,Stromberg JA,Zahiri HR,Pinczewski J,Holton LH 3rd,Silverman RP,Singh DP

更新日期：2016-10-01 00:00:00

abstract：:We demonstrate sodium pyruvate (NaPy) pre-treatment as a successful approach for pressure ulcer (PU) prevention by averting their aetiological origin-cell-level damage and death by large, sustained mechanical loads. We evaluated the NaPy pre-treatment effect on permeability changes in the cell's plasma membrane (PM) f...

journal_title：International wound journal

authors： Alvarez-Elizondo MB,Barenholz-Cohen T,Weihs D

更新日期：2019-10-01 00:00:00

abstract：:The aims of this randomised controlled study were to determine whether the application of silicone adhesive dressings with standard preventive care would reduce the impairment of skin integrity and to evaluate the subepidermal moisture (SEM) value in anatomical locations to predict impairment of skin integrity. Of the...

journal_title：International wound journal

authors： Lee YJ,Kim JY,Shin WY

更新日期：2019-03-01 00:00:00

abstract：:Negative pressure wound therapy (NPWT) contracts the wound and alters the pressure in the tissue of the wound edge, which accelerates wound healing. The aim of this study was to examine the effect of the type (foam or gauze) and size (small or large) of wound filler for NPWT on wound contraction and tissue pressure. N...

journal_title：International wound journal

authors： Anesäter E,Borgquist O,Hedström E,Waga J,Ingemansson R,Malmsjö M

更新日期：2011-08-01 00:00:00

abstract：:Necrobiosis lipoidica is a rare granulomatous disorder of the skin. In up to 30% of the affected patients it can lead to ulcerations, which can impair the quality of life and are also very difficult to treat. Its pathogenesis is not fully understood. Only few studies focussing on necrobiosis lipoidica can be found, bu...

journal_title：International wound journal

authors： Franklin C,Stoffels-Weindorf M,Hillen U,Dissemond J

更新日期：2015-10-01 00:00:00

abstract：:Patients with rheumatoid arthritis may develop leg ulcers of varied aetiologies, including venous disease, infection and inflammation (vasculitis or pyoderma gangrenosum). The leg ulcers in rheumatoid arthritis patients may involve several of these aetiological factors and are often difficult to heal. Both the ulcers ...

journal_title：International wound journal

authors： Coelho S,Amarelo M,Ryan S,Reddy M,Sibbald RG

更新日期：2004-04-01 00:00:00

abstract：:Although platelet gel is considered one of the most popular tools in the treatment of chronic ulcers, current consensus on its use is not unanimous. A prospective randomised trial was carried out at the Plastic Surgery Unit of the 'Salvatore Maugeri' Foundation Hospital of Pavia (Italy). The study involved 13 patients...

journal_title：International wound journal

authors： Scevola S,Nicoletti G,Brenta F,Isernia P,Maestri M,Faga A

更新日期：2010-06-01 00:00:00

abstract：:Patients with diabetes mellitus have a lifetime risk of 15% to 25% of developing diabetic foot ulcers (DFUs). DFU is associated with significant morbidity and mortality. Wound imaging systems are useful adjuncts in monitoring of wound progress. Our study aims to review existing literature on the available wound assess...

journal_title：International wound journal

authors： Chan KS,Lo ZJ

更新日期：2020-12-01 00:00:00

abstract：:Prevention and treatment of bacterial colonised/infected wounds are critical. Many commercially available silver dressings claim broad-spectrum bactericidal activity over days and are indicated for serious conditions including burns and ulcers. However, there is no peer-reviewed literature available for many newer dre...

journal_title：International wound journal

authors： Cavanagh MH,Burrell RE,Nadworny PL

更新日期：2010-10-01 00:00:00

abstract：:Increasing evidence within the literature has identified the presence of biofilms in chronic wounds and proposed that they contribute to delayed wound healing. This research aimed to investigate the presence of biofilm in diabetic foot ulcers (DFUs) using microscopy and molecular approaches and define if these are pre...

journal_title：International wound journal

authors： Johani K,Malone M,Jensen S,Gosbell I,Dickson H,Hu H,Vickery K

更新日期：2017-12-01 00:00:00

abstract：:Pressure injuries are key clinical indicators of care standard. In Australia, pressure injuries increase length of hospital stay by 4.31 and cost $285 million annually. This pilot study examined the effectiveness of sacral dressing in reducing the prevalence of pressure injuries in older, high-risk patients. A non ran...

journal_title：International wound journal

authors： Cubit K,McNally B,Lopez V

更新日期：2013-10-01 00:00:00

abstract：:A study conducted in an Australian home nursing service sought to ascertain whether the provision of funding for compression bandaging and medical footwear would impact on compression therapy use, wound healing and quality of life (QoL) among people with venous leg ulcers. Clients (n = 120) were randomly allocated to ...

journal_title：International wound journal

authors： Kapp S,Miller C,Elder K

更新日期：2012-10-01 00:00:00

abstract：:Symmetrical peripheral digital gangrene is a life-changing complication, caused by a pro-thrombotic life-threatening disease, such as disseminated intravascular coagulopathy (DIC) secondary to systemic infection. We describe the unusual case of a woman who developed symmetrical peripheral digital gangrene following DI...

journal_title：International wound journal

authors： Ghafoor SZ,MacRae EA,Harding KG,Patel GK

更新日期：2010-10-01 00:00:00

abstract：:Acellular dermal matrices can successfully heal wounds. This study's goal was to compare clinical outcomes of a novel, open-structure human reticular acellular dermis matrix (HR-ADM) to facilitate wound closure in non-healing diabetic foot ulcers (DFUs) versus DFUs treated with standard of care (SOC). Following a 2-we...

journal_title：International wound journal

authors： Zelen CM,Orgill DP,Serena T,Galiano R,Carter MJ,DiDomenico LA,Keller J,Kaufman J,Li WW

更新日期：2017-04-01 00:00:00

abstract：:The purpose of the study is to assess the effectiveness of low level laser therapy for wound healing when combined with the Extendicare Wound Prevention and Management Program. Sixteen residents at a Canadian Extendicare nursing home had a total of 27 sites treated consisting of 23 open wounds and 4 'at risk' areas. O...

journal_title：International wound journal

authors： Saltmarche AE

更新日期：2008-06-01 00:00:00

abstract：:Negative pressure wound therapy with instillation and dwell time (NPWTi-d) is an adjunctive therapy that can be used in the management of complex wounds with infection. NPWTi-d incorporates the intermittent instillation of a topical solution to the wound in a programmed manner. Unlike standard negative pressure wound ...

journal_title：International wound journal

authors： Anghel EL,Kim PJ,Attinger CE

更新日期：2016-09-01 00:00:00