Role of nicotinic acid and nicotinamide in nicorandil-induced ulcerations: from hypothesis to demonstration.

abstract：:The purpose of the study is to assess the effectiveness of low level laser therapy for wound healing when combined with the Extendicare Wound Prevention and Management Program. Sixteen residents at a Canadian Extendicare nursing home had a total of 27 sites treated consisting of 23 open wounds and 4 'at risk' areas. O...

journal_title：International wound journal

authors： Saltmarche AE

更新日期：2008-06-01 00:00:00

abstract：:Although chronic wounds have a high socio-economic impact, data on comparative effectiveness of treatments are rare. UrgoStart(®) is a hydroactive dressing containing a nano-oligosaccharide factor (NOSF). This study aimed at evaluating the cost-effectiveness of this NOSF-containing wound dressing in vascular leg ulcer...

journal_title：International wound journal

authors： Augustin M,Herberger K,Kroeger K,Muenter KC,Goepel L,Rychlik R

更新日期：2016-02-01 00:00:00

abstract：:An educational programme in wound healing was developed in France in 1998. The course lasts for 1 year and consists of 100 hours of interactive education including wound-healing principles, management of pressure ulcers, leg ulcers, diabetic foot ulcers, burns and trauma. The programme mixes theoretical and practical ...

journal_title：International wound journal

authors： Meaume S,Téot L,Dereure O

更新日期：2005-06-01 00:00:00

abstract：:Immunosuppressive therapy is increasingly being used in clinical practice and has been shown to affect wound healing to varying degrees. This article looks at the effects of the newer immunosuppressive agents on wound healing. It is shown that wound healing is impaired via different mechanisms. Some of the animal and ...

journal_title：International wound journal

authors： Bootun R

更新日期：2013-02-01 00:00:00

abstract：:The aim of this study was to investigate the relationship between perioperative corticosteroids administration and the incidence of pressure ulcers (PUs) in cardiovascular surgical patients. A retrospective analysis was performed on data from consecutive patients who had cardiac surgery in 2012. Univariate and multiva...

journal_title：International wound journal

authors： Chen HL,Shen WQ,Xu YH,Zhang Q,Wu J

更新日期：2015-10-01 00:00:00

abstract：:This retrospective study compared the clinical outcomes of negative pressure wound therapy with reticulated open cell foam (NPWT/ROCF) as delivered by Vacuum-Assisted Therapy(®) (V.A.C.(®) Therapy, KCI Licensing Inc., San Antonio, TX) to non-NPWT/ROCF conventional therapy (CT) in split-thickness skin graft (STSG) surv...

journal_title：International wound journal

authors： Blume PA,Key JJ,Thakor P,Thakor S,Sumpio B

更新日期：2010-12-01 00:00:00

abstract：:Non healing diabetic foot ulcers and the resulting potential amputations present significant costs to the health care system and reduce patient quality of life. The goal of diabetic foot ulcer treatment is to obtain wound closure as expeditiously as possible. The use of platelet-rich plasma (PRP) to enhance wound heal...

journal_title：International wound journal

authors： Saad Setta H,Elshahat A,Elsherbiny K,Massoud K,Safe I

更新日期：2011-06-01 00:00:00

abstract：:Acellular dermal matrices can successfully heal wounds. This study's goal was to compare clinical outcomes of a novel, open-structure human reticular acellular dermis matrix (HR-ADM) to facilitate wound closure in non-healing diabetic foot ulcers (DFUs) versus DFUs treated with standard of care (SOC). Following a 2-we...

journal_title：International wound journal

authors： Zelen CM,Orgill DP,Serena T,Galiano R,Carter MJ,DiDomenico LA,Keller J,Kaufman J,Li WW

更新日期：2017-04-01 00:00:00

abstract：:The purpose of this project was to evaluate associations of increasing diabetic foot surgery stage with postoperative outcome. This project, designed as a retrospective cohort model, was conducted at three large, urban referral-based diabetic foot clinics. The investigators abstracted medical records from 180 patients...

journal_title：International wound journal

authors： Armstrong DG,Lavery LA,Frykberg RG,Wu SC,Boulton AJ

更新日期：2006-09-01 00:00:00

abstract：:Marjolin's ulcer refers to malignant degeneration in a chronic wound. Although originally described in an area of burns scar, many other chronic wounds such as osteomyelitis sinus tracts, venous stasis ulcers and chronic pressure sores have the potential to undergo malignant transformation. We present an interesting c...

journal_title：International wound journal

authors： Fairbairn NG,Hamilton SA

更新日期：2011-10-01 00:00:00

abstract：:Ulcers in radiated skin continue to be a challenge for health care practitioners. Healing impairment in the setting of radiation-damaged tissue will most of the time lead to chronic wounds that reduce the patient's quality of life. In this review, we present an update of the pathophysiology of tissue damage caused by ...

journal_title：International wound journal

authors： Olascoaga A,Vilar-Compte D,Poitevin-Chacón A,Contreras-Ruiz J

更新日期：2008-06-01 00:00:00

abstract：:The initial care of burn wounds and choice of dressing are pivotal to optimally support the healing process. To ensure fast re-epithelialisation within 10-14 days and prevent complications, an optimal healing environment is essential. An innovative dressing based on nanocellulose was used for the treatment of burns in...

journal_title：International wound journal

authors： Resch A,Staud C,Radtke C

更新日期：2021-01-19 00:00:00

abstract：:For nearly two decades, Negative Pressure Wound Therapy (NPWT) has been used for temporary wound coverage as well as wound bed preparation. The addition of instillation and dwell time as an adjunct to NPWT (NPWTi-d) enables wound bed cleaning and improved wound bed granulation. Thirty patients with different types of ...

journal_title：International wound journal

authors： Diehm YF,Loew J,Will PA,Fischer S,Hundeshagen G,Ziegler B,Gazyakan E,Kneser U,Hirche C

更新日期：2020-12-01 00:00:00

abstract：:Chronic wounds are a growing challenge for physicians and health insurance agencies. The burden of affected patients is enormous, because of pain but also because of long-lasting therapies and dependence on nursing services. In other areas of medicine, computer-based diagnostics is established, yet, accurate wound doc...

journal_title：International wound journal

authors： Stremitzer S,Wild T,Hoelzenbein T

更新日期：2007-06-01 00:00:00

abstract：:Diabetic foot ulcers commonly precede diabetic foot osteomyelitis (DFO) and once the latter occurs, surgical management is often performed. The presence of osteomyelitis is an independent risk factor for the development of re-ulceration. We investigated the relationship between causative organisms in osteomyelitis and...

journal_title：International wound journal

authors： Schmidt BM,Ye W,Zhou S

更新日期：2020-12-01 00:00:00

abstract：:Surgical patients are at risk of developing a perioperative pressure injury (ORPI) during surgery. Accurate assessment and prompt implementation of prevention strategies or treatment of ORPI are dependent on knowledge and skills of operating room (OR) nurses. The study examined the knowledge and attitude of OR nurses ...

journal_title：International wound journal

authors： Khong BPC,Goh BC,Phang LY,David T

更新日期：2020-04-01 00:00:00

abstract：:Corticosteroid-induced skin atrophy (CISA) consists of a thinning of the skin and subcutaneous tissues, representing the natural consequence of a prolonged glucocorticosteroids use, both systemic as well as topical. It is characterised by the loss of elasticity and skin thickness, associated with an increased skin fra...

journal_title：International wound journal

authors： Vallini V,Rinaldi E,Mangano L,Modesti L,Ghelardini P,Roberts AT,Grazi G

更新日期：2020-06-01 00:00:00

abstract：:The use of a rigid disc as a barrier between the wound bed and the wound filler during negative pressure wound therapy (NPWT) has been suggested to prevent damage to exposed organs. However, it is important to determine that the effects of NPWT, such as wound contraction and fluid removal, are maintained during treatm...

journal_title：International wound journal

authors： Anesäter E,Roupé KM,Robertsson P,Borgquist O,Torbrand C,Ingemansson R,Lindstedt S,Malmsjö M

更新日期：2011-08-01 00:00:00

abstract：:We present a new surgical modification to allow propeller perforator flaps to cover pressure sores at various locations. We used a propeller perforator flap concept based on the detection of newly formed perforator vessels located 1 cm from the wound margin and stimulated by the chronic inflammation process. Between J...

journal_title：International wound journal

authors： Kelahmetoglu O,Van Landuyt K,Yagmur C,Sommeling CE,Keles MK,Tayfur V,Simsek T,Demirtas Y,Guneren E

更新日期：2017-12-01 00:00:00

abstract：:A case study reporting on the successful treatment of a patient affected by a basal cell carcinoma is submitted. Because the carcinoma had infiltrated deeply, a wide excision was necessary, including the removal of bone tissue. The deep tissue defect was treated with PROMOGRAN* Matrix, a protease-modulating matrix, to...

journal_title：International wound journal

authors： Tausche AK,Sebastian G

更新日期：2005-09-01 00:00:00

abstract：:Negative pressure wound therapy (NPWT) is an established method for the faster wound healing of chronic non-healing wounds. It is also used for laparostomy wounds and healing of split skin grafts. The commercially available machine and the consumables for NPWT are very expensive and economically not feasible in develo...

journal_title：International wound journal

authors： Gopal SV,Solomon A

更新日期：2019-02-01 00:00:00

abstract：:Negative pressure wound therapy with instillation and dwell time (NPWTi-d) is an adjunctive therapy that can be used in the management of complex wounds with infection. NPWTi-d incorporates the intermittent instillation of a topical solution to the wound in a programmed manner. Unlike standard negative pressure wound ...

journal_title：International wound journal

authors： Anghel EL,Kim PJ,Attinger CE

更新日期：2016-09-01 00:00:00

abstract：:Senescent fibroblasts, which are present in chronic ulcers, are the reason for the wound becoming chronic. In this study, we introduce full-thickness micro skin grafts in the ulcer, a surgical technique known as a 'nested graft', which gave encouraging results leading to complete wound healing in all patients. The ass...

journal_title：International wound journal

authors： Gualdi G,Crotti S,Monari P,Calzavara-Pinton P,Vitali M,Baronio M,Lougaris V

更新日期：2016-12-01 00:00:00

abstract：:Numerous comorbidities and cofactors have been known to influence wound healing processes. In this multicentre study, clinical data of 1 000 patients with chronic leg ulcers from ten specialised dermatological wound care centers were analysed. The patient cohort comprised 567 females and 433 males with an average age ...

journal_title：International wound journal

authors： Jockenhöfer F,Gollnick H,Herberger K,Isbary G,Renner R,Stücker M,Valesky E,Wollina U,Weichenthal M,Karrer S,Kuepper B,Roesch A,Dissemond J

更新日期：2016-10-01 00:00:00

abstract：:Wound clinics are seeing an increase in the number of 'complex' wounds, which arise as the result of the interaction between multiple coexisting systemic pathologies, environmental factors and local wound factors. These complex wounds require an approach to diagnosis and management that can encapsulate all these facto...

journal_title：International wound journal

authors： Harding K,Gray D,Timmons J,Hurd T

更新日期：2007-06-01 00:00:00

abstract：:Wound dehiscence is a surgical complication caused by the application of opposing and distracting forces tending to pull apart the suture line. In recent years, a novel negative pressure surgical management system has been developed to prevent surgical wound complications. This system creates a closed environment that...

journal_title：International wound journal

authors： Bollero D,Malvasio V,Catalano F,Stella M

更新日期：2015-02-01 00:00:00

abstract：:Gethin G, Cowman S. Case series of use of Manuka honey in leg ulceration. Abstract The historical and current literature reports the successful use of honey to manage a diversity of wound aetiologies. However, only in the last 40 years is research on its mode of action and contribution to wound healing being investiga...

journal_title：International wound journal

authors： Gethin G,Cowman S

更新日期：2005-03-01 00:00:00

abstract：:Wound healing is a complex cellular and biochemical process and can be affected by several systemic and local factors. In this study, we aimed to discuss the aetiologic factors of non-healing wounds and the management of this complicated process with current information. The medical data of the patients who were admit...

journal_title：International wound journal

authors： Calis H,Sengul S,Guler Y,Karabulut Z

更新日期：2020-04-01 00:00:00

abstract：:Ischaemia reperfusion (I/R) injury refers to tissue damage caused when blood supply returns to the tissue after a period of ischaemia. Matrix metalloproteinases (MMPs), neutrophil gelatinase-associated lipocalin (NGAL) and cytokines are biomarkers involved in several vascular complications. The aim of this study was t...

journal_title：International wound journal

authors： de Franciscis S,De Caridi G,Massara M,Spinelli F,Gallelli L,Buffone G,Caliò FG,Butrico L,Grande R,Serra R

更新日期：2016-10-01 00:00:00

abstract：:Pressure injuries (PIs) have now become a common complication of the elderly patients. Some studies have observed that pressure injuries may increase mortality, but this area of evidence has not been evaluated and summarised. The aim of this study was to compare the mortality of patients with pressure injuries and tho...

journal_title：International wound journal

authors： Song YP,Shen HW,Cai JY,Zha ML,Chen HL

更新日期：2019-12-01 00:00:00