Platelet-rich plasma versus platelet-poor plasma in the management of chronic diabetic foot ulcers: a comparative study.

Abstract:

:Non healing diabetic foot ulcers and the resulting potential amputations present significant costs to the health care system and reduce patient quality of life. The goal of diabetic foot ulcer treatment is to obtain wound closure as expeditiously as possible. The use of platelet-rich plasma (PRP) to enhance wound healing has increased dramatically over the last decade. However, controversies exist in the literature regarding the added benefit of this procedure. The aim of this study is to investigate the efficiency of platelet releasate on the healing of chronic diabetic ulcers in comparison with platelet-poor plasma (PPP). This study included 24 patients with chronic diabetic ulcers. They were systematically randomised into two groups: PRP group (n = 12) and PPP group (n = 12). The results showed that healing in PRP group was significantly faster (P < 0·005). PRP enhances healing of chronic diabetic foot ulcers.

journal_name

Int Wound J

authors

Saad Setta H,Elshahat A,Elsherbiny K,Massoud K,Safe I

doi

10.1111/j.1742-481X.2011.00797.x

subject

Has Abstract

pub_date

2011-06-01 00:00:00

pages

307-12

issue

3

eissn

1742-4801

issn

1742-481X

journal_volume

8

pub_type

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