Contact sensitivity in patients with venous leg ulcer: A multi-centric Indian study.

Abstract:

:Venous leg ulcers are the most common form of non-healing leg ulcers. They are subjected to treatments such as topical medications, dressings, and compression therapies. This can lead to exposure to a number of allergens with subsequent sensitisation and contact dermatitis of the regional skin. This may contribute to the poor ulcer healing. To detect the various contact sensitisers in patients with venous leg ulcers through patch testing, patients from 6 centres across India with venous leg ulcers of longer than 6 weeks duration were enrolled for the study. They were patch tested using a special parch test kit with 27 antigens. A total of 172 patients were included in the study; 82 (48.2%) tested positive for at least 1 antigen. Among them, polyvalent sensitisation was noted in 71% of patients. Wood tar mix (10.4%) and the framycetin (8.7%) were the most common allergens. There is a high frequency of allergic sensitisation to various ingredients of topical therapies used in the venous ulcer management, which may interfere with wound healing. Avoiding them can help obtain a better therapeutic outcome.

journal_name

Int Wound J

authors

Rai R,Shenoy MM,Viswanath V,Sarma N,Majid I,Dogra S

doi

10.1111/iwj.12905

subject

Has Abstract

pub_date

2018-08-01 00:00:00

pages

618-622

issue

4

eissn

1742-4801

issn

1742-481X

journal_volume

15

pub_type

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