Effects of immunosuppressive therapy on wound healing.

abstract：:Foot complications cause substantial morbidity in Tanzania, where 70% of leg amputations occur in diabetic patients. The Step by Step Foot Project was initiated to train healthcare personnel in diabetic foot management, facilitate transfer of knowledge and expertise, and improve patient education. The project comprise...

journal_title：International wound journal

authors： Abbas ZG,Lutale JK,Bakker K,Baker N,Archibald LK

更新日期：2011-04-01 00:00:00

abstract：:The purpose of this analysis was to evaluate the use of DermaPure, a decellularised human skin allograft, in the treatment of a variety of challenging wounds. This retrospective observational analysis reviewed a total of 37 patients from 29 different wound clinics across the USA. Each patient received one application ...

journal_title：International wound journal

authors： Kimmel H,Gittleman H

更新日期：2017-08-01 00:00:00

abstract：:Pathogenic, opportunistic, and commensal bacterial coexist in the intestinal tract, and imbalances among these strains have been linked to systemic inflammation and a variety of disease states. Similarly, human skin plays an important role as an interface between the body and the environment with an estimated 1 billio...

journal_title：International wound journal

authors： Knackstedt R,Knackstedt T,Gatherwright J

更新日期：2020-12-01 00:00:00

abstract：:Prevention and treatment of bacterial colonised/infected wounds are critical. Many commercially available silver dressings claim broad-spectrum bactericidal activity over days and are indicated for serious conditions including burns and ulcers. However, there is no peer-reviewed literature available for many newer dre...

journal_title：International wound journal

authors： Cavanagh MH,Burrell RE,Nadworny PL

更新日期：2010-10-01 00:00:00

abstract：:Wound complications following arterial surgery in the groin are relatively common and can result in significant morbidity and mortality. Vascularised muscle flaps (VMF) may be used as an adjunct to aid healing, either to manage complications or prophylactically. This series describes 46 patients who received sartorius...

journal_title：International wound journal

authors： Price A,Contractor U,White R,Williams I

更新日期：2020-12-01 00:00:00

abstract：:Numerous comorbidities and cofactors have been known to influence wound healing processes. In this multicentre study, clinical data of 1 000 patients with chronic leg ulcers from ten specialised dermatological wound care centers were analysed. The patient cohort comprised 567 females and 433 males with an average age ...

journal_title：International wound journal

authors： Jockenhöfer F,Gollnick H,Herberger K,Isbary G,Renner R,Stücker M,Valesky E,Wollina U,Weichenthal M,Karrer S,Kuepper B,Roesch A,Dissemond J

更新日期：2016-10-01 00:00:00

abstract：:The aim of the present study was to evaluate the efficacy of a new product (Neuropad repair foam(®)) in promoting skin hydration of the foot in type 2 diabetes. Included in this study were 20 type 2 diabetic patients (10 men, mean age 61·40 ± 2·44 years). Patients applied Neuropad repair foam(®) on the plantar aspect ...

journal_title：International wound journal

authors： Papanas N,Papazoglou D,Papatheodorou K,Maltezos E

更新日期：2011-06-01 00:00:00

abstract：:Covering the reconstructed area with a healthy soft-tissue envelope is a major challenge after limb-sparing surgery in patients with malignant bone and soft-tissue tumours. Negative pressure wound therapy (NPWT) of open wounds hastens healing and minimises the requirement for complex reconstructive soft-tissue surgery...

journal_title：International wound journal

authors： Mermerkaya U,Bekmez S,Alkan E,Ayvaz M,Tokgozoglu M

更新日期：2016-06-01 00:00:00

abstract：:The aim of this study was to determine the prevalence, severity, location, aetiology, treatment and healing of medical device-related pressure ulcers (PUs) in intensive care patients for up to 7 days. A prospective repeated measures study design was used. Patients in six intensive care units of two major medical centr...

journal_title：International wound journal

authors： Coyer FM,Stotts NA,Blackman VS

更新日期：2014-12-01 00:00:00

abstract：:Mohs micrographic surgery is the best therapeutical option for hand squamous cell carcinoma without bone involvement; however, the reconstruction of the surgical defect could be very difficult if the tumour is located in the distal phalanx of a finger. We present the case of a patient with a squamous cell carcinoma of...

journal_title：International wound journal

authors： Magliano J,Rossi V,Turra N,Bazzano C

更新日期：2019-06-01 00:00:00

abstract：:Fibronectin is an adhesive molecule that plays a crucial role in wound healing, particularly in extracellular matrix (ECM) formation and also in reepithelialisation. Fibronectin plays many different roles in the wound healing process because of the presence of specific function domains and binding sites in its structu...

journal_title：International wound journal

authors： Lenselink EA

更新日期：2015-06-01 00:00:00

abstract：:Chronic non-healing wounds are a burden in the Long-Term Care (LTC) sector, increasing costs, morbidity, and mortality and causing pain and suffering. The objective of this LTC Innovation pilot was to test the value of a promising new neuromuscular stimulation device in elevating the experience and satisfaction of the...

journal_title：International wound journal

authors： Harris C,Ramage D,Boloorchi A,Vaughan L,Kuilder G,Rakas S

更新日期：2019-02-01 00:00:00

abstract：:For the past 20 years, super-oxidised solutions (SOSs) have been shown to be potent antimicrobials and disinfectants via oxidative damage. However, the potential toxicity of SOSs on eukaryotic cells has not been documented in vitro. This is relevant because oxygen and chlorine reactive species may possibly induce agei...

journal_title：International wound journal

authors： González-Espinosa D,Pérez-Romano L,Guzmán-Soriano B,Arias E,Bongiovanni CM,Gutiérrez AA

更新日期：2007-09-01 00:00:00

abstract：:Symmetrical peripheral digital gangrene is a life-changing complication, caused by a pro-thrombotic life-threatening disease, such as disseminated intravascular coagulopathy (DIC) secondary to systemic infection. We describe the unusual case of a woman who developed symmetrical peripheral digital gangrene following DI...

journal_title：International wound journal

authors： Ghafoor SZ,MacRae EA,Harding KG,Patel GK

更新日期：2010-10-01 00:00:00

abstract：:Tendinopathy is a very common disease in the general population as well as in athletes. The aim of the present study was to examine the tendon thickness and cross-sectional area (CSA) in subjects with chronic mid-portion Achilles tendinopathy (AT) who engaged in either an eccentric exercise (EE) programme with vibrati...

journal_title：International wound journal

authors： Romero-Morales C,Javier Martín-Llantino P,Calvo-Lobo C,Palomo-López P,López-López D,Fernández-Carnero J,Rodríguez-Sanz D

更新日期：2019-04-01 00:00:00

abstract：:The aim of this study was to gain a better understanding of the venous leg ulcer (VLU) management in primary health care settings located in Melbourne metropolitan and rural Victoria, Australia. We explored health professionals' perspective on the use of the Australian and New Zealand Venous Leg Ulcer Clinical Practic...

journal_title：International wound journal

authors： Weller CD,Richards C,Turnour L,Team V

更新日期：2020-06-01 00:00:00

abstract：:Acellular dermal matrices can successfully heal wounds. This study's goal was to compare clinical outcomes of a novel, open-structure human reticular acellular dermis matrix (HR-ADM) to facilitate wound closure in non-healing diabetic foot ulcers (DFUs) versus DFUs treated with standard of care (SOC). Following a 2-we...

journal_title：International wound journal

authors： Zelen CM,Orgill DP,Serena T,Galiano R,Carter MJ,DiDomenico LA,Keller J,Kaufman J,Li WW

更新日期：2017-04-01 00:00:00

abstract：:Pressure injuries are one of the most common and costly complications occurring in US hospitals. With up to 3 million patients affected each year, hospital-acquired pressure injuries (HAPIs) place a substantial burden on the US healthcare system. In the current study, US hospital discharge records from 9.6 million pat...

journal_title：International wound journal

authors： Wassel CL,Delhougne G,Gayle JA,Dreyfus J,Larson B

更新日期：2020-12-01 00:00:00

abstract：:Venous leg ulcers are the most common form of non-healing leg ulcers. They are subjected to treatments such as topical medications, dressings, and compression therapies. This can lead to exposure to a number of allergens with subsequent sensitisation and contact dermatitis of the regional skin. This may contribute to ...

journal_title：International wound journal

authors： Rai R,Shenoy MM,Viswanath V,Sarma N,Majid I,Dogra S

更新日期：2018-08-01 00:00:00

abstract：:Continuous delivery of oxygen therapy has been observed to improve healing for individuals with an advanced diabetic foot ulcer (DFU). However, this intervention requires the purchasing of an oxygen delivery device and moist dressings. It is unknown whether this upfront financial investment represents good value for m...

journal_title：International wound journal

authors： Chan BC,Campbell KE

更新日期：2020-12-01 00:00:00

abstract：:Wound healing is a complex cellular and biochemical process and can be affected by several systemic and local factors. In this study, we aimed to discuss the aetiologic factors of non-healing wounds and the management of this complicated process with current information. The medical data of the patients who were admit...

journal_title：International wound journal

authors： Calis H,Sengul S,Guler Y,Karabulut Z

更新日期：2020-04-01 00:00:00

abstract：:Bacterial colonisation and infection remain the major causes of delayed healing and graft rejection following burns. Topical treatment is necessary to reduce the incidence of burn wound infection. Silver sulphadiazine (SD-Ag) is an often used microbicidal agent. However, this treatment produces adverse reactions and s...

journal_title：International wound journal

authors： Peral MC,Martinez MA,Valdez JC

更新日期：2009-02-01 00:00:00

abstract：:This data review reports the results of 15 patients who were treated with Vacuum-Assisted Closure (VAC) negative pressure therapy system in addition to the timed, intermittent delivery of an instilled topical solution for management of their complex, infected wounds. Prospective data for 15 patients treated with negat...

journal_title：International wound journal

authors： Gabriel A,Shores J,Heinrich C,Baqai W,Kalina S,Sogioka N,Gupta S

更新日期：2008-06-01 00:00:00

abstract：:The aim of this study was to retrospectively evaluate the clinical and culture-positive infection rates of open Gustilo/Anderson type II and III fractures using a protocol nanocrystalline silver wound dressing and hydrosurgical debridement. Retrospective case series through chart review on all type II and III open fra...

journal_title：International wound journal

authors： Keen JS,Desai PP,Smith CS,Suk M

更新日期：2012-02-01 00:00:00

abstract：:In addition to clinical signs of infection (e.g. inflammation, purulence and pain), a microbial count of ≥105 colony-forming units/g has historically been used to define wound infection. However, it is increasingly recognised that, rather than a high bioburden level alone being detrimental to wound healing, it is the ...

journal_title：International wound journal

authors： Lindsay S,Oates A,Bourdillon K

更新日期：2017-12-01 00:00:00

abstract：:Breast cancer is a serious disease in women. We estimated the global technical success rate and complication rates of percutaneous vacuum-assisted breast biopsy (VABB). PubMed, Embase, Web of Science, and Scopus databases were retrieved up to July 2018 to find studies in which technical success rate and complication r...

journal_title：International wound journal

authors： Fang M,Liu G,Luo G,Wu T

更新日期：2019-12-01 00:00:00

abstract：:Current embodiments of negative pressure wound therapy (NPWT) create a hermetically sealed chamber at the surface of the body using polyurethane foam connected to a vacuum pump, which is then covered by a flexible adhesive drape. Commercially available NPWT systems routinely use flexible polyethylene films that have a...

journal_title：International wound journal

authors： Daar DA,Wirth GA,Evans GR,Carmean M,Gordon IL

更新日期：2017-02-01 00:00:00

abstract：:A longitudinal observational study on a convenience sample was conducted between 4 January and 31 December of 2010 to evaluate clinical outcomes that occur when a new Interprofessional Diabetes Foot Ulcer Team (IPDFUT) helps in the management of diabetes-related foot ulcers (DFUs) in patients living in a small urban c...

journal_title：International wound journal

authors： Ogrin R,Houghton PE,Thompson GW

更新日期：2015-08-01 00:00:00

abstract：:Management of small-bowel fistulas which are in an open abdomen and have no soft tissue overlay or a fistula tract involves many complications and challenges. Controlling the local leakage of enteric contents has a central role in the success of medical treatment. There are several methods to deal with fistula dischar...

journal_title：International wound journal

authors： Miranda LE,Miranda AC

更新日期：2017-12-01 00:00:00

abstract：:Diabetic lower extremity wounds cause substantial burden to healthcare systems, costing tens of thousands of dollars per episode. Negative pressure wound therapy (NPWT) devices have been shown to be cost-effective at treating these wounds, but the traditional devices use bulky electrical pumps that require a durable m...

journal_title：International wound journal

authors： Hutton DW,Sheehan P

更新日期：2011-04-01 00:00:00