Keloid progression: a stiffness gap hypothesis.

abstract：:Keratin proteins have been shown to play a key role in wound healing. Controlled keratin gene (KRT) expression promotes cell growth, migration and differentiation, and as an example of the importance of keratin proteins, absence of KRT17 has been shown to delay wound closure. In addition, downregulation of KRT6 and KR...

journal_title：International wound journal

authors： Batzer AT,Marsh C,Kirsner RS

更新日期：2016-02-01 00:00:00

abstract：:Iodine-based products are antibacterial. The small iodine molecular size is ideally suited to treat surface critical colonisation. Inadine is a 10% povidone iodine dressing with the equivalent of 1% available iodine that is easily extracted from the viscose backing by serum or exudate. The use of hydrophilic polyethyl...

journal_title：International wound journal

authors： Sibbald RG,Elliott JA

更新日期：2017-04-01 00:00:00

abstract：:Reducing and preventing postoperative pain are currently a topic of great interest. There are different modalities for providing analgesia that can provide an alternative or adjunct to opioid therapy. One mode of therapy involves the use of portable pain pump devices that can deliver continuous local anaesthesia direc...

journal_title：International wound journal

authors： Scimeca CL,Fisher TK,Bharara M,Armstrong DG

更新日期：2010-06-01 00:00:00

abstract：:This study sought to both assist in the selection of flaps for ischial pressure wound re-construction and to evaluate the overall complication rates associated with re-construction. A retrospective medical record review was conducted for 78 patients following the surgical re-construction of an ischial pressure sore. R...

journal_title：International wound journal

authors： Ahluwalia R,Martin D,Mahoney JL

更新日期：2010-04-01 00:00:00

abstract：:The initial care of burn wounds and choice of dressing are pivotal to optimally support the healing process. To ensure fast re-epithelialisation within 10-14 days and prevent complications, an optimal healing environment is essential. An innovative dressing based on nanocellulose was used for the treatment of burns in...

journal_title：International wound journal

authors： Resch A,Staud C,Radtke C

更新日期：2021-01-19 00:00:00

abstract：:A new method (V.A.C.ULTA Therapy System, KCI USA, Inc., San Antonio, TX) combines the benefits of negative pressure wound therapy (NPWT; V.A.C. Therapy, KCI USA, Inc.) with regulated, periodic instillation of user-selected topical wound solutions (V.A.C. VeraFlo Therapy, KCI USA, Inc.). In simulated wound model studie...

journal_title：International wound journal

authors： Rycerz AM,Allen D,Lessing MC

更新日期：2013-12-01 00:00:00

abstract：:Pathogenic, opportunistic, and commensal bacterial coexist in the intestinal tract, and imbalances among these strains have been linked to systemic inflammation and a variety of disease states. Similarly, human skin plays an important role as an interface between the body and the environment with an estimated 1 billio...

journal_title：International wound journal

authors： Knackstedt R,Knackstedt T,Gatherwright J

更新日期：2020-12-01 00:00:00

abstract：:To characterise the role of ethnicity in the occurrence of foot ulcer disease in persons with diabetes, we analysed prospectively collected data for persons attending the diabetes clinic at Muhimbili National Hospital (MNH), Dar es Salaam, Tanzania. A case was defined as any adult presenting to MNH with an ulcer at or...

journal_title：International wound journal

authors： Abbas ZG,Lutale JK,Archibald LK

更新日期：2009-04-01 00:00:00

abstract：:Globally, wound care costs the health care system 2-3% of the total expenditure on health, which equates to several billion dollars annually. To date, there are little data on the cost and healing rates of various wounds. This has been partly because of the difficulty in tracking wound management as the majority of wo...

journal_title：International wound journal

authors： Khalil H,Cullen M,Chambers H,Carroll M,Walker J

更新日期：2016-10-01 00:00:00

abstract：:The critical problem of post-burn depigmentation is the lacking normal melanocytes. Auto-skin grafting and autologous non-cultured epidermal cell suspension have been used to improve the appearance. However, a large amount of skin graft is required of donor sites in the former method, while the latter method is though...

journal_title：International wound journal

authors： Chen B,Xu M,Li B

更新日期：2017-02-01 00:00:00

abstract：:Hydrofluoric acid (HF) burns cause immediate damage and painful long-term sequellae. Traditionally, chelating agents have been used as the initial treatment for such burns. We have introduced epidermal growth factor (EGF) into an HF model to compare EGF with Ca(2+) and Mg(2+) treatments; 40 Sprague Dawley rats were di...

journal_title：International wound journal

authors： Songur MK,Akdemir O,Lineaweaver WC,Cavusoglu T,Ozsarac M,Aktug H,Songur E,Tiftikcioglu YO

更新日期：2015-12-01 00:00:00

abstract：:Recurrence of breast cancer is a predominant fear for patients who were treated for breast cancer. Acute and late dermatologic effects of radiotherapy are not uncommon and could have similar characteristics to breast cancer recurrence. Thus, it is important to highlight key differences between the clinical and histolo...

journal_title：International wound journal

authors： Gutkin PM,Fernandez-Pol S,Horst KC

更新日期：2020-08-01 00:00:00

abstract：:The overall quality of evidence of autologous platelet-rich plasma (PRP) for treating chronic wounds remains low. While further well-designed clinical studies are clearly required to convincingly demonstrate the efficacy of autologous PRP in improved healing of venous leg ulcers (VLUs) and other chronic wounds, there ...

journal_title：International wound journal

authors： Weller CD,Gardiner EE,Arthur JF,Southey M,Andrews RK

更新日期：2019-06-01 00:00:00

abstract：:The aims of this randomised controlled study were to determine whether the application of silicone adhesive dressings with standard preventive care would reduce the impairment of skin integrity and to evaluate the subepidermal moisture (SEM) value in anatomical locations to predict impairment of skin integrity. Of the...

journal_title：International wound journal

authors： Lee YJ,Kim JY,Shin WY

更新日期：2019-03-01 00:00:00

abstract：:This prospective, non comparative study evaluated the safety and effectiveness of an adhesive gelling foam dressing in pressure ulcer management. Twenty-three subjects with exuding pressure ulcers were recruited from seven centres in the USA and Canada. Study treatment included an adhesive gelling foam dressing, optio...

journal_title：International wound journal

authors： Parish LC,Dryjski M,Cadden S,Versiva XC Pressure Ulcer Study Group.

更新日期：2008-03-01 00:00:00

abstract：:The use of lavage was compared to negative pressure wound therapy (NPWT) with instillation (NPWTi) to assess extent of soft tissue damage, debris removal and environmental cross-contamination susceptibility in three distinct models. Scanning electron microscopy in an ex vivo model showed increased visible tissue traum...

journal_title：International wound journal

authors： Allen D,LaBarbera LA,Bondre IL,Lessing MC,Rycerz AM,Kilpadi DV,Collins BA,Perkins J,McNulty AK

更新日期：2014-04-01 00:00:00

abstract：:Wound chronification and opportunistic infections stand as major factors leading to lower extremities amputations in diabetes. The molecular mechanisms underlying diabetic's torpid healing have not been elucidated. We present the case of a female diabetic patient that after a plantar abscess surgical drainage, tight g...

journal_title：International wound journal

authors： Berlanga-Acosta J,Mendoza-Mari Y,Martínez MD,Valdés-Perez C,Ojalvo AG,Armstrong DG

更新日期：2013-04-01 00:00:00

abstract：:The aim of this study was to retrospectively evaluate the clinical and culture-positive infection rates of open Gustilo/Anderson type II and III fractures using a protocol nanocrystalline silver wound dressing and hydrosurgical debridement. Retrospective case series through chart review on all type II and III open fra...

journal_title：International wound journal

authors： Keen JS,Desai PP,Smith CS,Suk M

更新日期：2012-02-01 00:00:00

abstract：:Corticosteroid-induced skin atrophy (CISA) consists of a thinning of the skin and subcutaneous tissues, representing the natural consequence of a prolonged glucocorticosteroids use, both systemic as well as topical. It is characterised by the loss of elasticity and skin thickness, associated with an increased skin fra...

journal_title：International wound journal

authors： Vallini V,Rinaldi E,Mangano L,Modesti L,Ghelardini P,Roberts AT,Grazi G

更新日期：2020-06-01 00:00:00

abstract：:Pressure ulcers are associated with a significant economic burden that, in many cases, is recognised as being avoidable. The effectiveness of pressure relieving surfaces is well documented and acknowledged in clinical guidelines on the prevention and management of pressure ulcers. Whilst pressure relieving surfaces ar...

journal_title：International wound journal

authors： Trueman P,Whitehead SJ

更新日期：2010-02-01 00:00:00

abstract：BACKGROUND:This study was designed to elucidate the in vivo efficacy of epidermal growth factor (EGF) on wound healing in non diabetic and diabetic rats. METHODS:Ninety-six male Wistar-Albino rats were randomly divided into six groups. Saline-moistened gauze, pure gelatin or EGF in gelatin-microsphere dressings were u...

journal_title：International wound journal

authors： Dogan S,Demirer S,Kepenekci I,Erkek B,Kiziltay A,Hasirci N,Müftüoglu S,Nazikoglu A,Renda N,Dincer UD,Elhan A,Kuterdem E

更新日期：2009-04-01 00:00:00

abstract：:Pre-tibial lacerations are complex wounds affecting a primarily aged population, with poor healing and a potentially significant impact on social well-being. Management of these wounds has changed little in 20 years, despite significant advances in wound care. A retrospective observational study was undertaken to obse...

journal_title：International wound journal

authors： McClelland HM,Stephenson J,Ousey KJ,Gillibrand WP,Underwood P

更新日期：2012-06-01 00:00:00

abstract：:Surgical patients are at risk of developing a perioperative pressure injury (ORPI) during surgery. Accurate assessment and prompt implementation of prevention strategies or treatment of ORPI are dependent on knowledge and skills of operating room (OR) nurses. The study examined the knowledge and attitude of OR nurses ...

journal_title：International wound journal

authors： Khong BPC,Goh BC,Phang LY,David T

更新日期：2020-04-01 00:00:00

abstract：:Pressure injuries are one of the most common and costly complications occurring in US hospitals. With up to 3 million patients affected each year, hospital-acquired pressure injuries (HAPIs) place a substantial burden on the US healthcare system. In the current study, US hospital discharge records from 9.6 million pat...

journal_title：International wound journal

authors： Wassel CL,Delhougne G,Gayle JA,Dreyfus J,Larson B

更新日期：2020-12-01 00:00:00

abstract：:Nicorandil is an original vasodilatator used to control angina by decreasing cardiac preload and afterload. Since 1997, many reports of single or multiple nicorandil-induced ulcerations have been published. To date, eight cases of nicorandil-induced fistula into adjacent organs have been described. The pathogeneses of...

journal_title：International wound journal

authors： Trechot P,Petitpain N,Guy C,Pinzano A,Javot L,Schmutz JL,Marie B,Barbaud A

更新日期：2013-04-01 00:00:00

abstract：:Venous leg ulcers are the most common form of non-healing leg ulcers. They are subjected to treatments such as topical medications, dressings, and compression therapies. This can lead to exposure to a number of allergens with subsequent sensitisation and contact dermatitis of the regional skin. This may contribute to ...

journal_title：International wound journal

authors： Rai R,Shenoy MM,Viswanath V,Sarma N,Majid I,Dogra S

更新日期：2018-08-01 00:00:00

abstract：:Ulcers in radiated skin continue to be a challenge for health care practitioners. Healing impairment in the setting of radiation-damaged tissue will most of the time lead to chronic wounds that reduce the patient's quality of life. In this review, we present an update of the pathophysiology of tissue damage caused by ...

journal_title：International wound journal

authors： Olascoaga A,Vilar-Compte D,Poitevin-Chacón A,Contreras-Ruiz J

更新日期：2008-06-01 00:00:00

abstract：:This data review reports the results of 15 patients who were treated with Vacuum-Assisted Closure (VAC) negative pressure therapy system in addition to the timed, intermittent delivery of an instilled topical solution for management of their complex, infected wounds. Prospective data for 15 patients treated with negat...

journal_title：International wound journal

authors： Gabriel A,Shores J,Heinrich C,Baqai W,Kalina S,Sogioka N,Gupta S

更新日期：2008-06-01 00:00:00

abstract：:Pressure ulcers (PUs) are one of the most prevalent adverse events in acute and chronic care. The root aetiological cause of PUs is sustained cell and tissue deformations, which triggers a synergistic tissue damage cascade that accelerates over relatively short time periods. Changes in skin microclimate conditions are...

journal_title：International wound journal

authors： Schwartz D,Gefen A

更新日期：2020-06-01 00:00:00

abstract：:In addition to clinical signs of infection (e.g. inflammation, purulence and pain), a microbial count of ≥105 colony-forming units/g has historically been used to define wound infection. However, it is increasingly recognised that, rather than a high bioburden level alone being detrimental to wound healing, it is the ...

journal_title：International wound journal

authors： Lindsay S,Oates A,Bourdillon K

更新日期：2017-12-01 00:00:00