Abstract:
:This is a prospective study with the aim to determine specific patterns of burn wound bacterial colonisation and antimicrobial resistance profiles. There is a high incidence of infections and septicaemia in post-burn patients, which, in turn, are associated with high morbidity and mortality, a fact that compelled us to undertake this study. The study was conducted over a period 11 months, from 1 August 2014 to 30 June 2015, in 50 burn patients admitted in our burn unit. Wound cultures were taken after 72 hours of admission from all the patients, and then, empirical systemic antibiotics were administered. For wound cultures; 1 cubic cm tissue was taken and placed in aerobic and anaerobic culture vials and transported to the microbiology lab under all aseptic precautions as soon as possible. At the time of fever any time after 72 hours of admission, 16 ml of blood was drawn under all aseptic precautions. Both aerobic and anaerobic blood culture vials were filled with 8 ml of blood each and transported to the microbiology lab. The results of culture and sensitivity reports of 50 patients were recorded. The data obtained was analysed using appropriate statistical analytical tests. The most common organism responsible for bacteraemia is Pseudomonas (43%). Most of the strains of organisms isolated were resistant to commonly used antibiotics in the hospital; Pseudomonas was found 100% resistant to a combination of ampicillin + sulbactum, ceftriaxone and was most often sensitive to imipenem, amikacin and vancomycin. Methicillin-resistant Staphylococcus aureus (MRSA) was also found resistant to commonly used antibiotics like ceftriaxone, ampicillin + sulbactum and ceftazidime + calvulanic acid. Linzolid and vancomycin were effective in 83% and 100% cases, respectively. We conclude that similar institution-specific studies should be conducted, and such studies will be helpful in providing useful guidelines for choosing effective empirical therapy that will have a great impact on the prevention of infection and its complications in burn patients because of bacteraemia.
journal_name
Int Wound Jjournal_title
International wound journalauthors
Mir MA,Khurram MF,Khan AHdoi
10.1111/iwj.12588subject
Has Abstractpub_date
2017-02-01 00:00:00pages
194-197issue
1eissn
1742-4801issn
1742-481Xjournal_volume
14pub_type
杂志文章abstract::Little is known about the cost-benefit of soft silicone foam dressings in pressure ulcer (PU) prevention among critically ill patients in the emergency department (ED) and intensive care unit (ICU). A randomised controlled trial to assess the efficacy of soft silicone foam dressings in preventing sacral and heel PUs w...
journal_title:International wound journal
pub_type: 杂志文章,随机对照试验
doi:10.1111/iwj.12160
更新日期:2015-06-01 00:00:00
abstract::Negative pressure wound therapy (NPWT) is considered an effective wound treatment, but there are a number of issues that need to be addressed for improvements to be made. This review aimed to explore the literature relating to the pain and skin trauma that may be experienced during NPWT. A literature search was carrie...
journal_title:International wound journal
pub_type: 杂志文章,评审
doi:10.1111/iwj.12059
更新日期:2015-02-01 00:00:00
abstract::Ulcers in radiated skin continue to be a challenge for health care practitioners. Healing impairment in the setting of radiation-damaged tissue will most of the time lead to chronic wounds that reduce the patient's quality of life. In this review, we present an update of the pathophysiology of tissue damage caused by ...
journal_title:International wound journal
pub_type: 杂志文章,评审
doi:10.1111/j.1742-481X.2008.00436.x
更新日期:2008-06-01 00:00:00
abstract::Chronic wounds are a growing challenge for physicians and health insurance agencies. The burden of affected patients is enormous, because of pain but also because of long-lasting therapies and dependence on nursing services. In other areas of medicine, computer-based diagnostics is established, yet, accurate wound doc...
journal_title:International wound journal
pub_type: 杂志文章
doi:10.1111/j.1742-481X.2007.00334.x
更新日期:2007-06-01 00:00:00
abstract::Hydrofluoric acid (HF) burns cause immediate damage and painful long-term sequellae. Traditionally, chelating agents have been used as the initial treatment for such burns. We have introduced epidermal growth factor (EGF) into an HF model to compare EGF with Ca(2+) and Mg(2+) treatments; 40 Sprague Dawley rats were di...
journal_title:International wound journal
pub_type: 杂志文章
doi:10.1111/iwj.12214
更新日期:2015-12-01 00:00:00
abstract::The aim of this study was to determine the prevalence, severity, location, aetiology, treatment and healing of medical device-related pressure ulcers (PUs) in intensive care patients for up to 7 days. A prospective repeated measures study design was used. Patients in six intensive care units of two major medical centr...
journal_title:International wound journal
pub_type: 杂志文章
doi:10.1111/iwj.12026
更新日期:2014-12-01 00:00:00
abstract::Numerous comorbidities and cofactors have been known to influence wound healing processes. In this multicentre study, clinical data of 1 000 patients with chronic leg ulcers from ten specialised dermatological wound care centers were analysed. The patient cohort comprised 567 females and 433 males with an average age ...
journal_title:International wound journal
pub_type: 杂志文章,多中心研究
doi:10.1111/iwj.12387
更新日期:2016-10-01 00:00:00
abstract::Biological alternatives to synthetic meshes are increasingly utilised in complex abdominal wall reconstruction. There is a lack of evidence demonstrating that non-cross-linked porcine acellular dermal matrix vascularizes and integrates with human tissue in suboptimal wound conditions. We aimed to evaluate these proper...
journal_title:International wound journal
pub_type: 杂志文章,评审
doi:10.1111/iwj.12558
更新日期:2016-10-01 00:00:00
abstract::Subcutaneous mastectomy, the first step in sexual reassignment surgery of female-to-male transsexuals, is associated with high rates of complication and revision surgery. Also, conventional electrosurgery and the associated thermal tissue damage may compromise outcome. This retrospective randomised clinical study eval...
journal_title:International wound journal
pub_type: 杂志文章
doi:10.1111/iwj.13382
更新日期:2020-10-01 00:00:00
abstract::Patients with rheumatoid arthritis may develop leg ulcers of varied aetiologies, including venous disease, infection and inflammation (vasculitis or pyoderma gangrenosum). The leg ulcers in rheumatoid arthritis patients may involve several of these aetiological factors and are often difficult to heal. Both the ulcers ...
journal_title:International wound journal
pub_type: 杂志文章
doi:10.1111/j.1742-481x.2004.0002.x
更新日期:2004-04-01 00:00:00
abstract::The prognosis of stage I pressure ulcers cannot be predicted; therefore, nursing interventions for preventing their deterioration have not been clearly established. This study describes the clinical course of stage I pressure ulcers and prospectively investigates the factors related to their deterioration. Thirty-one ...
journal_title:International wound journal
pub_type: 杂志文章
doi:10.1111/j.1742-481X.2006.00267.x
更新日期:2006-12-01 00:00:00
abstract::The aim of the present study was to evaluate the efficacy of a new product (Neuropad repair foam(®)) in promoting skin hydration of the foot in type 2 diabetes. Included in this study were 20 type 2 diabetic patients (10 men, mean age 61·40 ± 2·44 years). Patients applied Neuropad repair foam(®) on the plantar aspect ...
journal_title:International wound journal
pub_type: 杂志文章
doi:10.1111/j.1742-481X.2011.00786.x
更新日期:2011-06-01 00:00:00
abstract::Negative pressure wound therapy with instillation and dwell time (NPWTi-d) is an adjunctive therapy that can be used in the management of complex wounds with infection. NPWTi-d incorporates the intermittent instillation of a topical solution to the wound in a programmed manner. Unlike standard negative pressure wound ...
journal_title:International wound journal
pub_type: 杂志文章,评审
doi:10.1111/iwj.12664
更新日期:2016-09-01 00:00:00
abstract::The aim of the study was to compare three sampling techniques used in routine diagnostics to identify the microbiota in chronic venous leg ulcers. A total of 46 patients with persisting venous leg ulcers were included in the study. At inclusion, swab, biopsy and filter paper pad samples were collected. After 4 weeks, ...
journal_title:International wound journal
pub_type: 杂志文章
doi:10.1111/j.1742-481X.2011.00883.x
更新日期:2012-06-01 00:00:00
abstract::We aimed to systematically assess the overall value of interleukin 6 (IL-6) in diagnosing neonates with sepsis. A systematic literature search was conducted using the following electronic databases: PubMed, Embase, and Cochrane, to identify eligible studies through the index words updated till November 2018. Cross-sec...
journal_title:International wound journal
pub_type: 杂志文章,meta分析
doi:10.1111/iwj.13079
更新日期:2019-04-01 00:00:00
abstract::Wound dehiscence is a surgical complication caused by the application of opposing and distracting forces tending to pull apart the suture line. In recent years, a novel negative pressure surgical management system has been developed to prevent surgical wound complications. This system creates a closed environment that...
journal_title:International wound journal
pub_type: 杂志文章
doi:10.1111/iwj.12040
更新日期:2015-02-01 00:00:00
abstract::A 16-year-old girl with pyoderma gangrenosum (PG)-like skin lesions on the extremities, trunk and face developed Takayasu's arteritis (TA; pulseless disease). After 3 years under maintenance cyclosporin A therapy, the patient developed an ischaemic cerebral accident. Severe obstruction of both subclavian and left caro...
journal_title:International wound journal
pub_type: 杂志文章
doi:10.1111/j.1742-4801.2005.00103.x
更新日期:2005-12-01 00:00:00
abstract::Negative pressure wound therapy (NPWT) is an established method for the faster wound healing of chronic non-healing wounds. It is also used for laparostomy wounds and healing of split skin grafts. The commercially available machine and the consumables for NPWT are very expensive and economically not feasible in develo...
journal_title:International wound journal
pub_type: 杂志文章
doi:10.1111/iwj.13002
更新日期:2019-02-01 00:00:00
abstract::Enzymatic debridement with collagenase is a technique that is commonly used in clinical practice. This systematic review examines the effect of collagenase on all kinds of wounds, compared to an alternative therapy, on wound healing, wound bed characteristics, cost-effectiveness and the occurrence of adverse events. W...
journal_title:International wound journal
pub_type: 杂志文章,meta分析,评审
doi:10.1111/iwj.12760
更新日期:2017-12-01 00:00:00
abstract::This literature review aimed to provide a narrative review of evidence on validity of clinical and microbial indicators of infection and to gain insights into the diagnosis of infection in chronic leg ulcers (CLUs). A search was conducted in Cinahl, Medline, the Cochrane Library databases, Embase, Web of Science, Scie...
journal_title:International wound journal
pub_type: 杂志文章,评审
doi:10.1111/iwj.13069
更新日期:2019-06-01 00:00:00
abstract::A study conducted in an Australian home nursing service sought to ascertain whether the provision of funding for compression bandaging and medical footwear would impact on compression therapy use, wound healing and quality of life (QoL) among people with venous leg ulcers. Clients (n = 120) were randomly allocated to ...
journal_title:International wound journal
pub_type: 杂志文章,随机对照试验
doi:10.1111/j.1742-481X.2011.00908.x
更新日期:2012-10-01 00:00:00
abstract::This data review reports the results of 15 patients who were treated with Vacuum-Assisted Closure (VAC) negative pressure therapy system in addition to the timed, intermittent delivery of an instilled topical solution for management of their complex, infected wounds. Prospective data for 15 patients treated with negat...
journal_title:International wound journal
pub_type: 杂志文章
doi:10.1111/j.1742-481X.2007.00423.x
更新日期:2008-06-01 00:00:00
abstract::Wide and deep wound defects are a challenge to surgeons, particularly when aggressive or more radical operations are unavailable. This article introduces refined techniques, indications and the clinical experience of the application of negative pressure wound therapy (NPWT) as an easy ancillary wound dressing method f...
journal_title:International wound journal
pub_type: 杂志文章
doi:10.1111/j.1742-481X.2011.00813.x
更新日期:2011-08-01 00:00:00
abstract::This study sought to both assist in the selection of flaps for ischial pressure wound re-construction and to evaluate the overall complication rates associated with re-construction. A retrospective medical record review was conducted for 78 patients following the surgical re-construction of an ischial pressure sore. R...
journal_title:International wound journal
pub_type: 杂志文章
doi:10.1111/j.1742-481X.2010.00662.x
更新日期:2010-04-01 00:00:00
abstract::Pressure ulcers are associated with a significant economic burden that, in many cases, is recognised as being avoidable. The effectiveness of pressure relieving surfaces is well documented and acknowledged in clinical guidelines on the prevention and management of pressure ulcers. Whilst pressure relieving surfaces ar...
journal_title:International wound journal
pub_type: 杂志文章
doi:10.1111/j.1742-481X.2009.00647.x
更新日期:2010-02-01 00:00:00
abstract::In the present study, the age- and sex-related differences in platelet ultrastructure were investigated using transmission electron microscopy (TEM). A total of 15 healthy volunteers were grouped according to age, with 5 people in each of the following groups: young group (25-45 years), middle-aged group (46-65 years)...
journal_title:International wound journal
pub_type: 杂志文章
doi:10.1111/iwj.13214
更新日期:2019-12-01 00:00:00
abstract::Acellular dermal matrices can successfully heal wounds. This study's goal was to compare clinical outcomes of a novel, open-structure human reticular acellular dermis matrix (HR-ADM) to facilitate wound closure in non-healing diabetic foot ulcers (DFUs) versus DFUs treated with standard of care (SOC). Following a 2-we...
journal_title:International wound journal
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1111/iwj.12600
更新日期:2017-04-01 00:00:00
abstract::Foreign modelling agent reactions (FMAR) are the result of the injection of unapproved high-viscosity fluids with the purpose of cosmetic body modelling. Its consequences lead to ulceration, disfigurement and even death, and it has reached epidemic proportions in several regions of the world. We describe a series of p...
journal_title:International wound journal
pub_type: 杂志文章,评审
doi:10.1111/iwj.12643
更新日期:2017-06-01 00:00:00
abstract::A new method (V.A.C.ULTA Therapy System, KCI USA, Inc., San Antonio, TX) combines the benefits of negative pressure wound therapy (NPWT; V.A.C. Therapy, KCI USA, Inc.) with regulated, periodic instillation of user-selected topical wound solutions (V.A.C. VeraFlo Therapy, KCI USA, Inc.). In simulated wound model studie...
journal_title:International wound journal
pub_type: 杂志文章,评审
doi:10.1111/iwj.12171
更新日期:2013-12-01 00:00:00
abstract::This prospective, non comparative study evaluated the safety and effectiveness of an adhesive gelling foam dressing in pressure ulcer management. Twenty-three subjects with exuding pressure ulcers were recruited from seven centres in the USA and Canada. Study treatment included an adhesive gelling foam dressing, optio...
journal_title:International wound journal
pub_type: 临床试验,杂志文章,多中心研究
doi:10.1111/j.1742-481X.2007.00428.x
更新日期:2008-03-01 00:00:00