Sodium pyruvate pre-treatment prevents cell death due to localised, damaging mechanical strains in the context of pressure ulcers.

abstract：:Pressure injuries are one of the most common and costly complications occurring in US hospitals. With up to 3 million patients affected each year, hospital-acquired pressure injuries (HAPIs) place a substantial burden on the US healthcare system. In the current study, US hospital discharge records from 9.6 million pat...

journal_title：International wound journal

authors： Wassel CL,Delhougne G,Gayle JA,Dreyfus J,Larson B

更新日期：2020-12-01 00:00:00

abstract：:Pressure ulcers (PUs) are a common secondary complication experienced by community dwelling individuals with spinal cord injury (SCI). There is a paucity of literature on the health economic impact of PU in SCI population from a societal perspective. The objective of this study was to determine the resource use and co...

journal_title：International wound journal

authors： Chan BC,Nanwa N,Mittmann N,Bryant D,Coyte PC,Houghton PE

更新日期：2013-08-01 00:00:00

abstract：:Keloids are fibroproliferative skin disorders characterised clinically by continuous horizontal progression and post-surgical recurrence and histologically by the accumulation of collagen and fibroblast ingredients. Till now, their aetiology remains clear, which may cover genetic, environmental and metabolic factors. ...

journal_title：International wound journal

authors： Huang C,Liu L,You Z,Wang B,Du Y,Ogawa R

更新日期：2017-10-01 00:00:00

abstract：:Diabetic lower extremity wounds cause substantial burden to healthcare systems, costing tens of thousands of dollars per episode. Negative pressure wound therapy (NPWT) devices have been shown to be cost-effective at treating these wounds, but the traditional devices use bulky electrical pumps that require a durable m...

journal_title：International wound journal

authors： Hutton DW,Sheehan P

更新日期：2011-04-01 00:00:00

abstract：:A 16-year-old girl with pyoderma gangrenosum (PG)-like skin lesions on the extremities, trunk and face developed Takayasu's arteritis (TA; pulseless disease). After 3 years under maintenance cyclosporin A therapy, the patient developed an ischaemic cerebral accident. Severe obstruction of both subclavian and left caro...

journal_title：International wound journal

authors： Dourmishev AL,Serafimova DK,Vassileva SG,Dourmishev LA,Schwartz RA

更新日期：2005-12-01 00:00:00

abstract：:For the past 20 years, super-oxidised solutions (SOSs) have been shown to be potent antimicrobials and disinfectants via oxidative damage. However, the potential toxicity of SOSs on eukaryotic cells has not been documented in vitro. This is relevant because oxygen and chlorine reactive species may possibly induce agei...

journal_title：International wound journal

authors： González-Espinosa D,Pérez-Romano L,Guzmán-Soriano B,Arias E,Bongiovanni CM,Gutiérrez AA

更新日期：2007-09-01 00:00:00

abstract：:In May 2011, an international panel of wound care experts from multiple disciplines convened to develop this document to summarise the evolution of negative pressure wound therapy (NPWT) technology devices over the past 15 years, specifically concentrating on the V.A.C.(®) Therapy (KCI USA, Inc., San Antonio, TX) fam...

journal_title：International wound journal

authors： Gupta S

更新日期：2012-08-01 00:00:00

abstract：:Negative pressure wound therapy (NPWT) is considered an effective wound treatment, but there are a number of issues that need to be addressed for improvements to be made. This review aimed to explore the literature relating to the pain and skin trauma that may be experienced during NPWT. A literature search was carrie...

journal_title：International wound journal

authors： Upton D,Andrews A

更新日期：2015-02-01 00:00:00

abstract：:Management of small-bowel fistulas which are in an open abdomen and have no soft tissue overlay or a fistula tract involves many complications and challenges. Controlling the local leakage of enteric contents has a central role in the success of medical treatment. There are several methods to deal with fistula dischar...

journal_title：International wound journal

authors： Miranda LE,Miranda AC

更新日期：2017-12-01 00:00:00

abstract：:Assess the outcome of a standardised protocol for the treatment of post-operative wound infection in patients undergoing deformity correction for neuro-muscular scoliosis (NMS). Retrospective review of 443 consecutive patients with a minimum 18 months' follow-up, following a primary posterior deformity correction for ...

journal_title：International wound journal

authors： Haleem S,Edwin J,Bashir MA,Soltani S,Nadarajah R,Kieser DC

更新日期：2020-06-01 00:00:00

abstract：:The aim of the study was to evaluate the maintenance of the 30° side-lying lateral tilt position among aged care residents at the risk of developing pressure injuries when using the standard care pillow and a purpose-designed positioning device. An observational study was conducted. Participants were monitored during ...

journal_title：International wound journal

authors： Kapp S,Gerdtz M,Gefen A,Prematunga R,Santamaria N

更新日期：2019-10-01 00:00:00

abstract：:Leg ulcer management is complex, time-consuming and of high socio-economic importance. Data on cost-of-illness in leg ulcer care are sparse. The objective of this study was to evaluate the cost-of-illness in leg ulcer treatment in the metropolitan area of Hamburg. About 147 institutions involved in wound care particip...

journal_title：International wound journal

authors： Augustin M,Brocatti LK,Rustenbach SJ,Schäfer I,Herberger K

更新日期：2014-06-01 00:00:00

abstract：:Bacterial colonisation and infection remain the major causes of delayed healing and graft rejection following burns. Topical treatment is necessary to reduce the incidence of burn wound infection. Silver sulphadiazine (SD-Ag) is an often used microbicidal agent. However, this treatment produces adverse reactions and s...

journal_title：International wound journal

authors： Peral MC,Martinez MA,Valdez JC

更新日期：2009-02-01 00:00:00

abstract：:This study sought to both assist in the selection of flaps for ischial pressure wound re-construction and to evaluate the overall complication rates associated with re-construction. A retrospective medical record review was conducted for 78 patients following the surgical re-construction of an ischial pressure sore. R...

journal_title：International wound journal

authors： Ahluwalia R,Martin D,Mahoney JL

更新日期：2010-04-01 00:00:00

abstract：:In recent years, oxidative stress and free radicals have been implicated in impaired wound healing. Grape (Vitis vinifera) seed extract (GSE) possesses anti-inflammatory and antioxidant properties. The present study was undertaken to assess the potential activity of grape seed hydroalcoholic extract in wound healing i...

journal_title：International wound journal

authors： Hemmati AA,Aghel N,Rashidi I,Gholampur-Aghdami A

更新日期：2011-10-01 00:00:00

abstract：:Chronic wounds are a significant problem in Australia. The health care-related costs of chronic wounds in Australia are considerable, equivalent to more than AUD $3.5 billion, approximately 2% of national health care expenditure. Chronic wounds can also have a significant negative impact on the health-related quality ...

journal_title：International wound journal

authors： McCosker L,Tulleners R,Cheng Q,Rohmer S,Pacella T,Graves N,Pacella R

更新日期：2019-02-01 00:00:00

abstract：:Venous leg ulcers are the most common form of non-healing leg ulcers. They are subjected to treatments such as topical medications, dressings, and compression therapies. This can lead to exposure to a number of allergens with subsequent sensitisation and contact dermatitis of the regional skin. This may contribute to ...

journal_title：International wound journal

authors： Rai R,Shenoy MM,Viswanath V,Sarma N,Majid I,Dogra S

更新日期：2018-08-01 00:00:00

abstract：:This is a prospective study with the aim to determine specific patterns of burn wound bacterial colonisation and antimicrobial resistance profiles. There is a high incidence of infections and septicaemia in post-burn patients, which, in turn, are associated with high morbidity and mortality, a fact that compelled us t...

journal_title：International wound journal

authors： Mir MA,Khurram MF,Khan AH

更新日期：2017-02-01 00:00:00

abstract：:Wound clinics are seeing an increase in the number of 'complex' wounds, which arise as the result of the interaction between multiple coexisting systemic pathologies, environmental factors and local wound factors. These complex wounds require an approach to diagnosis and management that can encapsulate all these facto...

journal_title：International wound journal

authors： Harding K,Gray D,Timmons J,Hurd T

更新日期：2007-06-01 00:00:00

abstract：:An educational programme in wound healing was developed in France in 1998. The course lasts for 1 year and consists of 100 hours of interactive education including wound-healing principles, management of pressure ulcers, leg ulcers, diabetic foot ulcers, burns and trauma. The programme mixes theoretical and practical ...

journal_title：International wound journal

authors： Meaume S,Téot L,Dereure O

更新日期：2005-06-01 00:00:00

abstract：:Combinations of various treatment modalities were shown to be more effective than monotherapy when treating hypertrophic scars and keloids. This study was conducted to assess the effectiveness of combination therapy with non-ablative fractional laser and intralesional steroid injection. From May 2015 to June 2017, a t...

journal_title：International wound journal

authors： Shin J,Cho JT,Park SI,Jung SN

更新日期：2019-12-01 00:00:00

abstract：:Wound healing is a complex cellular and biochemical process and can be affected by several systemic and local factors. In this study, we aimed to discuss the aetiologic factors of non-healing wounds and the management of this complicated process with current information. The medical data of the patients who were admit...

journal_title：International wound journal

authors： Calis H,Sengul S,Guler Y,Karabulut Z

更新日期：2020-04-01 00:00:00

abstract：:Deep sternal wound infection (DSWI) is a fatal complication after median sternotomy. This study was to assess the effect of vacuum-assisted closure (VAC) combined with bi-pectoral muscle advancement flap therapy on rehabilitation for the treatment of DSWI. Fifty-two patients with DSWI underwent treatment of VAC and bi...

journal_title：International wound journal

authors： Wang C,Zhang J,Liu Z

更新日期：2020-04-01 00:00:00

abstract：:Diabetic foot ulcers commonly precede diabetic foot osteomyelitis (DFO) and once the latter occurs, surgical management is often performed. The presence of osteomyelitis is an independent risk factor for the development of re-ulceration. We investigated the relationship between causative organisms in osteomyelitis and...

journal_title：International wound journal

authors： Schmidt BM,Ye W,Zhou S

更新日期：2020-12-01 00:00:00

abstract：:The initial care of burn wounds and choice of dressing are pivotal to optimally support the healing process. To ensure fast re-epithelialisation within 10-14 days and prevent complications, an optimal healing environment is essential. An innovative dressing based on nanocellulose was used for the treatment of burns in...

journal_title：International wound journal

authors： Resch A,Staud C,Radtke C

更新日期：2021-01-19 00:00:00

abstract：:The use of lavage was compared to negative pressure wound therapy (NPWT) with instillation (NPWTi) to assess extent of soft tissue damage, debris removal and environmental cross-contamination susceptibility in three distinct models. Scanning electron microscopy in an ex vivo model showed increased visible tissue traum...

journal_title：International wound journal

authors： Allen D,LaBarbera LA,Bondre IL,Lessing MC,Rycerz AM,Kilpadi DV,Collins BA,Perkins J,McNulty AK

更新日期：2014-04-01 00:00:00

abstract：:Digital ulcers (DUs) represent one of the major burdens for patients with systemic sclerosis (SSc), especially when associated with skin calcinosis (SC). The aim of this work is to evaluate the impact of SC in DUs of patients with SSc for clinical characteristics and prognosis assessed by the wound bed score (WBS). We...

journal_title：International wound journal

authors： Barsotti S,Venturini V,Di Battista M,Janowska A,Dini V,Della Rossa A,Mosca M

更新日期：2020-12-01 00:00:00

abstract：:We aimed to systematically assess the overall value of interleukin 6 (IL-6) in diagnosing neonates with sepsis. A systematic literature search was conducted using the following electronic databases: PubMed, Embase, and Cochrane, to identify eligible studies through the index words updated till November 2018. Cross-sec...

journal_title：International wound journal

authors： Sun B,Liang LF,Li J,Yang D,Zhao XB,Zhang KG

更新日期：2019-04-01 00:00:00

abstract：:Surgical patients are at risk of developing a perioperative pressure injury (ORPI) during surgery. Accurate assessment and prompt implementation of prevention strategies or treatment of ORPI are dependent on knowledge and skills of operating room (OR) nurses. The study examined the knowledge and attitude of OR nurses ...

journal_title：International wound journal

authors： Khong BPC,Goh BC,Phang LY,David T

更新日期：2020-04-01 00:00:00

abstract：:In addition to clinical signs of infection (e.g. inflammation, purulence and pain), a microbial count of ≥105 colony-forming units/g has historically been used to define wound infection. However, it is increasingly recognised that, rather than a high bioburden level alone being detrimental to wound healing, it is the ...

journal_title：International wound journal

authors： Lindsay S,Oates A,Bourdillon K

更新日期：2017-12-01 00:00:00