Skin grafting for the treatment of chronic leg ulcers - a systematic review in evidence-based medicine.

abstract：:Use of silicone derivative and onion extract had been reported in the prevention of hypertrophic scarring. Our experience showed the preventive use of silicone derivative plus onion extract gel on hypertrophic scars after median sternotomy. In a randomized, double blinded, placebo-controlled study, 60 patients after m...

journal_title：International wound journal

authors： Jenwitheesuk K,Surakunprapha P,Jenwitheesuk K,Kuptarnond C,Prathanee S,Intanoo W

更新日期：2012-08-01 00:00:00

abstract：:In addition to clinical signs of infection (e.g. inflammation, purulence and pain), a microbial count of ≥105 colony-forming units/g has historically been used to define wound infection. However, it is increasingly recognised that, rather than a high bioburden level alone being detrimental to wound healing, it is the ...

journal_title：International wound journal

authors： Lindsay S,Oates A,Bourdillon K

更新日期：2017-12-01 00:00:00

abstract：:This literature review aimed to provide a narrative review of evidence on validity of clinical and microbial indicators of infection and to gain insights into the diagnosis of infection in chronic leg ulcers (CLUs). A search was conducted in Cinahl, Medline, the Cochrane Library databases, Embase, Web of Science, Scie...

journal_title：International wound journal

authors： Bui UT,Finlayson K,Edwards H

更新日期：2019-06-01 00:00:00

abstract：:Ischaemia reperfusion (I/R) injury refers to tissue damage caused when blood supply returns to the tissue after a period of ischaemia. Matrix metalloproteinases (MMPs), neutrophil gelatinase-associated lipocalin (NGAL) and cytokines are biomarkers involved in several vascular complications. The aim of this study was t...

journal_title：International wound journal

authors： de Franciscis S,De Caridi G,Massara M,Spinelli F,Gallelli L,Buffone G,Caliò FG,Butrico L,Grande R,Serra R

更新日期：2016-10-01 00:00:00

abstract：:Osteoradionecrosis is an exceptional complication after the treatment of breast carcinoma. We report here a 63-year-old woman who presented with osteoradionecrosis of the sternum 17 years after initial treatment for breast cancer. Difficulty in diagnosing the lesion and its management is discussed. ...

journal_title：International wound journal

authors： Pandey M,Chandramohan KN,Mathew A

更新日期：2004-06-01 00:00:00

abstract：:Marjolin's ulcer refers to malignant degeneration in a chronic wound. Although originally described in an area of burns scar, many other chronic wounds such as osteomyelitis sinus tracts, venous stasis ulcers and chronic pressure sores have the potential to undergo malignant transformation. We present an interesting c...

journal_title：International wound journal

authors： Fairbairn NG,Hamilton SA

更新日期：2011-10-01 00:00:00

abstract：:Pressure ulcers (PUs) are one of the most prevalent adverse events in acute and chronic care. The root aetiological cause of PUs is sustained cell and tissue deformations, which triggers a synergistic tissue damage cascade that accelerates over relatively short time periods. Changes in skin microclimate conditions are...

journal_title：International wound journal

authors： Schwartz D,Gefen A

更新日期：2020-06-01 00:00:00

abstract：:This study sought to both assist in the selection of flaps for ischial pressure wound re-construction and to evaluate the overall complication rates associated with re-construction. A retrospective medical record review was conducted for 78 patients following the surgical re-construction of an ischial pressure sore. R...

journal_title：International wound journal

authors： Ahluwalia R,Martin D,Mahoney JL

更新日期：2010-04-01 00:00:00

abstract：:Patients with rheumatoid arthritis may develop leg ulcers of varied aetiologies, including venous disease, infection and inflammation (vasculitis or pyoderma gangrenosum). The leg ulcers in rheumatoid arthritis patients may involve several of these aetiological factors and are often difficult to heal. Both the ulcers ...

journal_title：International wound journal

authors： Coelho S,Amarelo M,Ryan S,Reddy M,Sibbald RG

更新日期：2004-04-01 00:00:00

abstract：:The overall quality of evidence of autologous platelet-rich plasma (PRP) for treating chronic wounds remains low. While further well-designed clinical studies are clearly required to convincingly demonstrate the efficacy of autologous PRP in improved healing of venous leg ulcers (VLUs) and other chronic wounds, there ...

journal_title：International wound journal

authors： Weller CD,Gardiner EE,Arthur JF,Southey M,Andrews RK

更新日期：2019-06-01 00:00:00

abstract：:Current embodiments of negative pressure wound therapy (NPWT) create a hermetically sealed chamber at the surface of the body using polyurethane foam connected to a vacuum pump, which is then covered by a flexible adhesive drape. Commercially available NPWT systems routinely use flexible polyethylene films that have a...

journal_title：International wound journal

authors： Daar DA,Wirth GA,Evans GR,Carmean M,Gordon IL

更新日期：2017-02-01 00:00:00

abstract：:An educational programme in wound healing was developed in France in 1998. The course lasts for 1 year and consists of 100 hours of interactive education including wound-healing principles, management of pressure ulcers, leg ulcers, diabetic foot ulcers, burns and trauma. The programme mixes theoretical and practical ...

journal_title：International wound journal

authors： Meaume S,Téot L,Dereure O

更新日期：2005-06-01 00:00:00

abstract：:The aim of this study was to retrospectively evaluate the clinical and culture-positive infection rates of open Gustilo/Anderson type II and III fractures using a protocol nanocrystalline silver wound dressing and hydrosurgical debridement. Retrospective case series through chart review on all type II and III open fra...

journal_title：International wound journal

authors： Keen JS,Desai PP,Smith CS,Suk M

更新日期：2012-02-01 00:00:00

abstract：:Pressure injuries (PIs) have now become a common complication of the elderly patients. Some studies have observed that pressure injuries may increase mortality, but this area of evidence has not been evaluated and summarised. The aim of this study was to compare the mortality of patients with pressure injuries and tho...

journal_title：International wound journal

authors： Song YP,Shen HW,Cai JY,Zha ML,Chen HL

更新日期：2019-12-01 00:00:00

abstract：:Previous studies have reported that the use of incisional negative pressure wound therapy (INPWT) might reduce the incidence of wound infections, although its mechanism remains unknown. We designed a prospective study to explore the effects of INPWT on different stages of the wound healing process. After meeting the i...

journal_title：International wound journal

authors： Rashed A,Csiszar M,Beledi A,Gombocz K

更新日期：2020-11-25 00:00:00

abstract：:The purpose of this project was to evaluate associations of increasing diabetic foot surgery stage with postoperative outcome. This project, designed as a retrospective cohort model, was conducted at three large, urban referral-based diabetic foot clinics. The investigators abstracted medical records from 180 patients...

journal_title：International wound journal

authors： Armstrong DG,Lavery LA,Frykberg RG,Wu SC,Boulton AJ

更新日期：2006-09-01 00:00:00

abstract：:Facial traumatic events are commonly encountered in plastic and reconstructive surgery. Primary reconstruction is a reliable procedure with function and aesthetic considerations. We conduct a retrospective study of the experience of reconstructing facial traumatic defects in the first stage. One hundred and thirty-two...

journal_title：International wound journal

authors： Chen B,Song H,Gao Q,Xu M,Chai J

更新日期：2017-02-01 00:00:00

abstract：:The initial care of burn wounds and choice of dressing are pivotal to optimally support the healing process. To ensure fast re-epithelialisation within 10-14 days and prevent complications, an optimal healing environment is essential. An innovative dressing based on nanocellulose was used for the treatment of burns in...

journal_title：International wound journal

authors： Resch A,Staud C,Radtke C

更新日期：2021-01-19 00:00:00

abstract：:Numerous comorbidities and cofactors have been known to influence wound healing processes. In this multicentre study, clinical data of 1 000 patients with chronic leg ulcers from ten specialised dermatological wound care centers were analysed. The patient cohort comprised 567 females and 433 males with an average age ...

journal_title：International wound journal

authors： Jockenhöfer F,Gollnick H,Herberger K,Isbary G,Renner R,Stücker M,Valesky E,Wollina U,Weichenthal M,Karrer S,Kuepper B,Roesch A,Dissemond J

更新日期：2016-10-01 00:00:00

abstract：:Continuous delivery of oxygen therapy has been observed to improve healing for individuals with an advanced diabetic foot ulcer (DFU). However, this intervention requires the purchasing of an oxygen delivery device and moist dressings. It is unknown whether this upfront financial investment represents good value for m...

journal_title：International wound journal

authors： Chan BC,Campbell KE

更新日期：2020-12-01 00:00:00

abstract：:The aim of this study was to investigate the relationship between perioperative corticosteroids administration and the incidence of pressure ulcers (PUs) in cardiovascular surgical patients. A retrospective analysis was performed on data from consecutive patients who had cardiac surgery in 2012. Univariate and multiva...

journal_title：International wound journal

authors： Chen HL,Shen WQ,Xu YH,Zhang Q,Wu J

更新日期：2015-10-01 00:00:00

abstract：:Cushing's syndrome is a condition caused by high levels of glucocorticoids, or most commonly as a result of prolonged exposure to exogenous steroids. Clinical features include diabetes, hypertension, obesity, skin atrophy, immune suppression and delayed wound healing. We report a patient with iatrogenic Cushing's synd...

journal_title：International wound journal

authors： Biswas M,Gibby O,Ivanova-Stoilova T,Harding K

更新日期：2011-02-01 00:00:00

abstract：:Reducing and preventing postoperative pain are currently a topic of great interest. There are different modalities for providing analgesia that can provide an alternative or adjunct to opioid therapy. One mode of therapy involves the use of portable pain pump devices that can deliver continuous local anaesthesia direc...

journal_title：International wound journal

authors： Scimeca CL,Fisher TK,Bharara M,Armstrong DG

更新日期：2010-06-01 00:00:00

abstract：:Over the last decade, maggot debridement therapy (MDT) has been recognized by many clinicians as a potential adjunct to conventional therapy, and many patients with non healing, chronic ulcers have been treated. Numerous case reports and case series have described the successful use of MDT in a variety of ulcers. Howe...

journal_title：International wound journal

authors： Zarchi K,Jemec GB

更新日期：2012-10-01 00:00:00

abstract：:A longitudinal observational study on a convenience sample was conducted between 4 January and 31 December of 2010 to evaluate clinical outcomes that occur when a new Interprofessional Diabetes Foot Ulcer Team (IPDFUT) helps in the management of diabetes-related foot ulcers (DFUs) in patients living in a small urban c...

journal_title：International wound journal

authors： Ogrin R,Houghton PE,Thompson GW

更新日期：2015-08-01 00:00:00

abstract：:Negative pressure wound therapy (NPWT) is an established method for the faster wound healing of chronic non-healing wounds. It is also used for laparostomy wounds and healing of split skin grafts. The commercially available machine and the consumables for NPWT are very expensive and economically not feasible in develo...

journal_title：International wound journal

authors： Gopal SV,Solomon A

更新日期：2019-02-01 00:00:00

abstract：:Pressure ulcers (PUs) are a common secondary complication experienced by community dwelling individuals with spinal cord injury (SCI). There is a paucity of literature on the health economic impact of PU in SCI population from a societal perspective. The objective of this study was to determine the resource use and co...

journal_title：International wound journal

authors： Chan BC,Nanwa N,Mittmann N,Bryant D,Coyte PC,Houghton PE

更新日期：2013-08-01 00:00:00

abstract：:An understanding of risk factors associated with mortality among pressure ulcer patients can inform prognostic counselling and treatment plans. This retrospective cohort study examined associations of comorbid illness, demographic characteristics and laboratory values with 90-day and 90- to 180-day mortality in adult ...

journal_title：International wound journal

authors： Flattau A,Blank AE

更新日期：2014-02-01 00:00:00

abstract：:Ulcers in radiated skin continue to be a challenge for health care practitioners. Healing impairment in the setting of radiation-damaged tissue will most of the time lead to chronic wounds that reduce the patient's quality of life. In this review, we present an update of the pathophysiology of tissue damage caused by ...

journal_title：International wound journal

authors： Olascoaga A,Vilar-Compte D,Poitevin-Chacón A,Contreras-Ruiz J

更新日期：2008-06-01 00:00:00

abstract：:Pre-tibial lacerations are complex wounds affecting a primarily aged population, with poor healing and a potentially significant impact on social well-being. Management of these wounds has changed little in 20 years, despite significant advances in wound care. A retrospective observational study was undertaken to obse...

journal_title：International wound journal

authors： McClelland HM,Stephenson J,Ousey KJ,Gillibrand WP,Underwood P

更新日期：2012-06-01 00:00:00