Enzymatic debridement with collagenase in wounds and ulcers: a systematic review and meta-analysis.

abstract：:Diabetic foot ulcers commonly precede diabetic foot osteomyelitis (DFO) and once the latter occurs, surgical management is often performed. The presence of osteomyelitis is an independent risk factor for the development of re-ulceration. We investigated the relationship between causative organisms in osteomyelitis and...

journal_title：International wound journal

authors： Schmidt BM,Ye W,Zhou S

更新日期：2020-12-01 00:00:00

abstract：:There are many porcine burn models that create burns using different materials (e.g. metal, water) and different burn conditions (e.g. temperature and duration of exposure). This review aims to determine whether a pooled analysis of these studies can provide insight into the burn materials and conditions required to c...

journal_title：International wound journal

authors： Andrews CJ,Cuttle L

更新日期：2017-12-01 00:00:00

abstract：:Pressure ulcers are associated with a significant economic burden that, in many cases, is recognised as being avoidable. The effectiveness of pressure relieving surfaces is well documented and acknowledged in clinical guidelines on the prevention and management of pressure ulcers. Whilst pressure relieving surfaces ar...

journal_title：International wound journal

authors： Trueman P,Whitehead SJ

更新日期：2010-02-01 00:00:00

abstract：:Foreign modelling agent reactions (FMAR) are the result of the injection of unapproved high-viscosity fluids with the purpose of cosmetic body modelling. Its consequences lead to ulceration, disfigurement and even death, and it has reached epidemic proportions in several regions of the world. We describe a series of p...

journal_title：International wound journal

authors： Martínez-Villarreal AA,Asz-Sigall D,Gutiérrez-Mendoza D,Serena TE,Lozano-Platonoff A,Sanchez-Cruz LY,Toussaint-Caire S,Domínguez-Cherit J,López-García LA,Cárdenas-Sánchez A,Contreras-Ruiz J

更新日期：2017-06-01 00:00:00

abstract：:The aim of the present study was to evaluate the efficacy of a new product (Neuropad repair foam(®)) in promoting skin hydration of the foot in type 2 diabetes. Included in this study were 20 type 2 diabetic patients (10 men, mean age 61·40 ± 2·44 years). Patients applied Neuropad repair foam(®) on the plantar aspect ...

journal_title：International wound journal

authors： Papanas N,Papazoglou D,Papatheodorou K,Maltezos E

更新日期：2011-06-01 00:00:00

abstract：:The aim of this systematic review was to determine the supporting evidence for the clinical use of hydrogel dressings as a first aid measure for burn wound management in the pre-hospital setting. Two authors searched three databases (Ovid Medline, Ovid Embase and The Cochrane Library) for relevant English language art...

journal_title：International wound journal

authors： Goodwin NS,Spinks A,Wasiak J

更新日期：2016-08-01 00:00:00

abstract：:Acellular dermal matrices can successfully heal wounds. This study's goal was to compare clinical outcomes of a novel, open-structure human reticular acellular dermis matrix (HR-ADM) to facilitate wound closure in non-healing diabetic foot ulcers (DFUs) versus DFUs treated with standard of care (SOC). Following a 2-we...

journal_title：International wound journal

authors： Zelen CM,Orgill DP,Serena T,Galiano R,Carter MJ,DiDomenico LA,Keller J,Kaufman J,Li WW

更新日期：2017-04-01 00:00:00

abstract：:Negative pressure therapy has been successfully applied to clean, closed incisions in patients at high-risk for wound complications. Using laser Doppler flowmetry, we evaluated peristernal perfusion after cardiac surgery via median sternotomy, assessing the influence of mammary artery harvesting and the impact of nega...

journal_title：International wound journal

authors： Atkins BZ,Tetterton JK,Petersen RP,Hurley K,Wolfe WG

更新日期：2011-02-01 00:00:00

abstract：:Chronic wounds, including diabetic foot ulcers, pressure ulcers and venous leg ulcers, represent a significant cause of morbidity in developed countries, predominantly in older patients. The aetiology of these wounds is probably multifactorial, but the role of bacteria in their pathogenesis is still unclear. Moreover,...

journal_title：International wound journal

authors： Baffoni M,Bessa LJ,Grande R,Di Giulio M,Mongelli M,Ciarelli A,Cellini L

更新日期：2012-10-01 00:00:00

abstract：:To characterise the role of ethnicity in the occurrence of foot ulcer disease in persons with diabetes, we analysed prospectively collected data for persons attending the diabetes clinic at Muhimbili National Hospital (MNH), Dar es Salaam, Tanzania. A case was defined as any adult presenting to MNH with an ulcer at or...

journal_title：International wound journal

authors： Abbas ZG,Lutale JK,Archibald LK

更新日期：2009-04-01 00:00:00

abstract：:Little is known about the cost-benefit of soft silicone foam dressings in pressure ulcer (PU) prevention among critically ill patients in the emergency department (ED) and intensive care unit (ICU). A randomised controlled trial to assess the efficacy of soft silicone foam dressings in preventing sacral and heel PUs w...

journal_title：International wound journal

authors： Santamaria N,Liu W,Gerdtz M,Sage S,McCann J,Freeman A,Vassiliou T,DeVincentis S,Ng AW,Manias E,Knott J,Liew D

更新日期：2015-06-01 00:00:00

abstract：:Prevention and treatment of bacterial colonised/infected wounds are critical. Many commercially available silver dressings claim broad-spectrum bactericidal activity over days and are indicated for serious conditions including burns and ulcers. However, there is no peer-reviewed literature available for many newer dre...

journal_title：International wound journal

authors： Cavanagh MH,Burrell RE,Nadworny PL

更新日期：2010-10-01 00:00:00

abstract：:To describe the steps needed for a successful implementation of an e-health programme (the Mobile Wound Care system) in rural Victoria, Australia and to provide recommendations for future e-health initiatives. Wound care is a major burden on the health care system. Optimal wound care was found to be impeded by issues ...

journal_title：International wound journal

authors： Khalil H,Cullen M,Chambers H,Steers N,Walker J

更新日期：2014-06-01 00:00:00

abstract：:The purpose of this analysis was to evaluate the use of DermaPure, a decellularised human skin allograft, in the treatment of a variety of challenging wounds. This retrospective observational analysis reviewed a total of 37 patients from 29 different wound clinics across the USA. Each patient received one application ...

journal_title：International wound journal

authors： Kimmel H,Gittleman H

更新日期：2017-08-01 00:00:00

abstract：:Senescent fibroblasts, which are present in chronic ulcers, are the reason for the wound becoming chronic. In this study, we introduce full-thickness micro skin grafts in the ulcer, a surgical technique known as a 'nested graft', which gave encouraging results leading to complete wound healing in all patients. The ass...

journal_title：International wound journal

authors： Gualdi G,Crotti S,Monari P,Calzavara-Pinton P,Vitali M,Baronio M,Lougaris V

更新日期：2016-12-01 00:00:00

abstract：:Hydrofluoric acid (HF) burns cause immediate damage and painful long-term sequellae. Traditionally, chelating agents have been used as the initial treatment for such burns. We have introduced epidermal growth factor (EGF) into an HF model to compare EGF with Ca(2+) and Mg(2+) treatments; 40 Sprague Dawley rats were di...

journal_title：International wound journal

authors： Songur MK,Akdemir O,Lineaweaver WC,Cavusoglu T,Ozsarac M,Aktug H,Songur E,Tiftikcioglu YO

更新日期：2015-12-01 00:00:00

abstract：:Tendinopathy is a very common disease in the general population as well as in athletes. The aim of the present study was to examine the tendon thickness and cross-sectional area (CSA) in subjects with chronic mid-portion Achilles tendinopathy (AT) who engaged in either an eccentric exercise (EE) programme with vibrati...

journal_title：International wound journal

authors： Romero-Morales C,Javier Martín-Llantino P,Calvo-Lobo C,Palomo-López P,López-López D,Fernández-Carnero J,Rodríguez-Sanz D

更新日期：2019-04-01 00:00:00

abstract：:In recent years, oxidative stress and free radicals have been implicated in impaired wound healing. Grape (Vitis vinifera) seed extract (GSE) possesses anti-inflammatory and antioxidant properties. The present study was undertaken to assess the potential activity of grape seed hydroalcoholic extract in wound healing i...

journal_title：International wound journal

authors： Hemmati AA,Aghel N,Rashidi I,Gholampur-Aghdami A

更新日期：2011-10-01 00:00:00

abstract：:The aim of this study was to gain a better understanding of the venous leg ulcer (VLU) management in primary health care settings located in Melbourne metropolitan and rural Victoria, Australia. We explored health professionals' perspective on the use of the Australian and New Zealand Venous Leg Ulcer Clinical Practic...

journal_title：International wound journal

authors： Weller CD,Richards C,Turnour L,Team V

更新日期：2020-06-01 00:00:00

abstract：:The aim of this study was to determine the prevalence, severity, location, aetiology, treatment and healing of medical device-related pressure ulcers (PUs) in intensive care patients for up to 7 days. A prospective repeated measures study design was used. Patients in six intensive care units of two major medical centr...

journal_title：International wound journal

authors： Coyer FM,Stotts NA,Blackman VS

更新日期：2014-12-01 00:00:00

abstract：:Indwelling foreign-body infections are a critical medical problem, especially in immunocompromised patients. To examine the pathogenicity of biofilm-forming bacteria settling on foreign materials, mice implanted with plastic discs were infected with Staphylococcus aureus. After opening a wide subcutaneous pocket on th...

journal_title：International wound journal

authors： Makino T,Jimi S,Oyama T,Nakano Y,Hamamoto K,Mamishin K,Yahiro T,Hara S,Takata T,Ohjimi H

更新日期：2015-04-01 00:00:00

abstract：:Mohs micrographic surgery is the best therapeutical option for hand squamous cell carcinoma without bone involvement; however, the reconstruction of the surgical defect could be very difficult if the tumour is located in the distal phalanx of a finger. We present the case of a patient with a squamous cell carcinoma of...

journal_title：International wound journal

authors： Magliano J,Rossi V,Turra N,Bazzano C

更新日期：2019-06-01 00:00:00

abstract：:Chemotaxis, mitogenesis, motogenesis and cytoprotection are common cellular events involved in both tumourigenesis and tissue repair, which appear amplified upon growth factors exposure. Epidermal growth factor (EGF) promotes these events in epithelial and mesenchymal cells through the binding to a specific tyrosine k...

journal_title：International wound journal

authors： Berlanga-Acosta J,Gavilondo-Cowley J,López-Saura P,González-López T,Castro-Santana MD,López-Mola E,Guillén-Nieto G,Herrera-Martinez L

更新日期：2009-10-01 00:00:00

abstract：:Pressure injuries are key clinical indicators of care standard. In Australia, pressure injuries increase length of hospital stay by 4.31 and cost $285 million annually. This pilot study examined the effectiveness of sacral dressing in reducing the prevalence of pressure injuries in older, high-risk patients. A non ran...

journal_title：International wound journal

authors： Cubit K,McNally B,Lopez V

更新日期：2013-10-01 00:00:00

abstract：:Even though it is estimated that at least 300 000 people in Canada may be affected by chronic oedema/lymphoedema, recognition of the seriousness of this chronic disease in health care is scarce. Lymphoedema affects up to 70% of breast and prostate cancer patients, substantially increasing their postoperative medical c...

journal_title：International wound journal

authors： Keast DH,Despatis M,Allen JO,Brassard A

更新日期：2015-06-01 00:00:00

abstract：:A sandwich graft was applied to the debrided cortical bone layer of the tibia in the case of a 72-year-old male patient with full-thickness necrotic burn injury. The combined graft consisted of a dermal template material and autologous split thickness skin graft. After application, the graft was found totally accepted...

journal_title：International wound journal

authors： Gáspár K,Erdei I,Péter Z,Dezsö B,Hunyadi J,Juhász I

更新日期：2006-03-01 00:00:00

abstract：:Infiltration of surgical wounds with long-acting local anaesthetics (LA) is used to reduce postoperative incisional pain. We hypothesised that infiltration with LA interferes with wound healing in rats. Seventy-two rats were allocated into nine groups. After intraperitoneal anaesthesia, the interscapular dorsal region...

journal_title：International wound journal

authors： Abrão J,Fernandes CR,White PF,Shimano AC,Okubo R,Lima GB,Bachur JA,Garcia SB

更新日期：2014-08-01 00:00:00

abstract：:Negative pressure wound therapy (NPWT) is an established method for the faster wound healing of chronic non-healing wounds. It is also used for laparostomy wounds and healing of split skin grafts. The commercially available machine and the consumables for NPWT are very expensive and economically not feasible in develo...

journal_title：International wound journal

authors： Gopal SV,Solomon A

更新日期：2019-02-01 00:00:00

abstract：:Covering the reconstructed area with a healthy soft-tissue envelope is a major challenge after limb-sparing surgery in patients with malignant bone and soft-tissue tumours. Negative pressure wound therapy (NPWT) of open wounds hastens healing and minimises the requirement for complex reconstructive soft-tissue surgery...

journal_title：International wound journal

authors： Mermerkaya U,Bekmez S,Alkan E,Ayvaz M,Tokgozoglu M

更新日期：2016-06-01 00:00:00

abstract：:The aim of this study was to investigate the relationship between perioperative corticosteroids administration and the incidence of pressure ulcers (PUs) in cardiovascular surgical patients. A retrospective analysis was performed on data from consecutive patients who had cardiac surgery in 2012. Univariate and multiva...

journal_title：International wound journal

authors： Chen HL,Shen WQ,Xu YH,Zhang Q,Wu J

更新日期：2015-10-01 00:00:00