Abstract:
:A new method (V.A.C.ULTA Therapy System, KCI USA, Inc., San Antonio, TX) combines the benefits of negative pressure wound therapy (NPWT; V.A.C. Therapy, KCI USA, Inc.) with regulated, periodic instillation of user-selected topical wound solutions (V.A.C. VeraFlo Therapy, KCI USA, Inc.). In simulated wound model studies comparing solution distribution using NPWT with and without a soak phase, the instillation soak phase allowed for uniform solution distribution across the wound bed, whereas continuous (no soak) irrigation resulted in uneven coverage. Additional in vitro work illustrated that bacterial particle aerosolisation during wound cleansing was significantly decreased using NPWT with instillation (NPWTi) versus commercially available low-pressure wound cleansers (P < 0·05). In porcine studies, NPWT with saline instillation induced 43% more granulation tissue versus NPWT (P < 0·05) and was as effective at wound cleansing as pulsed lavage. These studies have demonstrated that NPWTi may be an effective wound management therapy that provides both wound cleansing and NPWT benefits.
journal_name
Int Wound Jjournal_title
International wound journalauthors
Rycerz AM,Allen D,Lessing MCdoi
10.1111/iwj.12171subject
Has Abstractpub_date
2013-12-01 00:00:00pages
20-4eissn
1742-4801issn
1742-481Xjournal_volume
10 Suppl 1pub_type
杂志文章,评审abstract::Perianal fistula is a common disease that affects particular patients with inflammatory bowel disease. Honey has been used as a natural remedy for centuries for the treatment of various disorders. We report a patient with persistent fistulas, in whom conventional medical and surgical therapy failed. In this case, most...
journal_title:International wound journal
pub_type: 杂志文章
doi:10.1111/j.1742-481X.2011.00844.x
更新日期:2012-02-01 00:00:00
abstract::Negative pressure wound therapy with instillation and dwell time (NPWTi-d) is an automated system used to deliver, dwell, and remove topical solutions from the wound bed. Recently, a reticulated open cell foam dressing with through holes (ROCF-CC) was developed, which assists with wound cleansing by removing thick exu...
journal_title:International wound journal
pub_type: 杂志文章
doi:10.1111/iwj.13097
更新日期:2019-06-01 00:00:00
abstract::Negative pressure therapy has been successfully applied to clean, closed incisions in patients at high-risk for wound complications. Using laser Doppler flowmetry, we evaluated peristernal perfusion after cardiac surgery via median sternotomy, assessing the influence of mammary artery harvesting and the impact of nega...
journal_title:International wound journal
pub_type: 杂志文章
doi:10.1111/j.1742-481X.2010.00743.x
更新日期:2011-02-01 00:00:00
abstract::In May 2011, an international panel of wound care experts from multiple disciplines convened to develop this document to summarise the evolution of negative pressure wound therapy (NPWT) technology devices over the past 15 years, specifically concentrating on the V.A.C.(®) Therapy (KCI USA, Inc., San Antonio, TX) fam...
journal_title:International wound journal
pub_type:
doi:10.1111/j.1742-481X.2012.00978.x
更新日期:2012-08-01 00:00:00
abstract::Patients with rheumatoid arthritis may develop leg ulcers of varied aetiologies, including venous disease, infection and inflammation (vasculitis or pyoderma gangrenosum). The leg ulcers in rheumatoid arthritis patients may involve several of these aetiological factors and are often difficult to heal. Both the ulcers ...
journal_title:International wound journal
pub_type: 杂志文章
doi:10.1111/j.1742-481x.2004.0002.x
更新日期:2004-04-01 00:00:00
abstract::The aim of the present study was to evaluate the efficacy of a new product (Neuropad repair foam(®)) in promoting skin hydration of the foot in type 2 diabetes. Included in this study were 20 type 2 diabetic patients (10 men, mean age 61·40 ± 2·44 years). Patients applied Neuropad repair foam(®) on the plantar aspect ...
journal_title:International wound journal
pub_type: 杂志文章
doi:10.1111/j.1742-481X.2011.00786.x
更新日期:2011-06-01 00:00:00
abstract::We evaluated the efficacy and safety of a povidone-iodine (PVP-I) foam dressing (Betafoam) for donor site dressing versus a hydrocellular foam dressing (Allevyn) and petrolatum gauze. This prospective Phase 4 study was conducted between March 2016 and April 2017 at eight sites in Korea. A total of 106 consenting patie...
journal_title:International wound journal
pub_type: 杂志文章
doi:10.1111/iwj.13043
更新日期:2019-04-01 00:00:00
abstract::Fibronectin is an adhesive molecule that plays a crucial role in wound healing, particularly in extracellular matrix (ECM) formation and also in reepithelialisation. Fibronectin plays many different roles in the wound healing process because of the presence of specific function domains and binding sites in its structu...
journal_title:International wound journal
pub_type: 杂志文章,评审
doi:10.1111/iwj.12109
更新日期:2015-06-01 00:00:00
abstract::This is a prospective study with the aim to determine specific patterns of burn wound bacterial colonisation and antimicrobial resistance profiles. There is a high incidence of infections and septicaemia in post-burn patients, which, in turn, are associated with high morbidity and mortality, a fact that compelled us t...
journal_title:International wound journal
pub_type: 杂志文章
doi:10.1111/iwj.12588
更新日期:2017-02-01 00:00:00
abstract::Osteoradionecrosis is an exceptional complication after the treatment of breast carcinoma. We report here a 63-year-old woman who presented with osteoradionecrosis of the sternum 17 years after initial treatment for breast cancer. Difficulty in diagnosing the lesion and its management is discussed. ...
journal_title:International wound journal
pub_type: 杂志文章
doi:10.1111/j.1742-4801.2004.00037.x
更新日期:2004-06-01 00:00:00
abstract::Indwelling foreign-body infections are a critical medical problem, especially in immunocompromised patients. To examine the pathogenicity of biofilm-forming bacteria settling on foreign materials, mice implanted with plastic discs were infected with Staphylococcus aureus. After opening a wide subcutaneous pocket on th...
journal_title:International wound journal
pub_type: 杂志文章
doi:10.1111/iwj.12061
更新日期:2015-04-01 00:00:00
abstract::The use of a rigid disc as a barrier between the wound bed and the wound filler during negative pressure wound therapy (NPWT) has been suggested to prevent damage to exposed organs. However, it is important to determine that the effects of NPWT, such as wound contraction and fluid removal, are maintained during treatm...
journal_title:International wound journal
pub_type: 杂志文章
doi:10.1111/j.1742-481X.2011.00805.x
更新日期:2011-08-01 00:00:00
abstract::Randomised clinical trials (RCTs) to evaluate diabetic foot wound therapies have systematically eliminated large acute wounds from evaluation, focusing only on smaller chronic wounds. The purpose of this study was to evaluate the proportion and rate of wound healing in acute and chronic wounds after partial foot amput...
journal_title:International wound journal
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1111/j.1742-481X.2006.00270.x
更新日期:2007-03-01 00:00:00
abstract::The overall quality of evidence of autologous platelet-rich plasma (PRP) for treating chronic wounds remains low. While further well-designed clinical studies are clearly required to convincingly demonstrate the efficacy of autologous PRP in improved healing of venous leg ulcers (VLUs) and other chronic wounds, there ...
journal_title:International wound journal
pub_type: 杂志文章
doi:10.1111/iwj.13098
更新日期:2019-06-01 00:00:00
abstract::This retrospective study compared the clinical outcomes of negative pressure wound therapy with reticulated open cell foam (NPWT/ROCF) as delivered by Vacuum-Assisted Therapy(®) (V.A.C.(®) Therapy, KCI Licensing Inc., San Antonio, TX) to non-NPWT/ROCF conventional therapy (CT) in split-thickness skin graft (STSG) surv...
journal_title:International wound journal
pub_type: 杂志文章
doi:10.1111/j.1742-481X.2010.00728.x
更新日期:2010-12-01 00:00:00
abstract::Iodine-based products are antibacterial. The small iodine molecular size is ideally suited to treat surface critical colonisation. Inadine is a 10% povidone iodine dressing with the equivalent of 1% available iodine that is easily extracted from the viscose backing by serum or exudate. The use of hydrophilic polyethyl...
journal_title:International wound journal
pub_type: 杂志文章
doi:10.1111/iwj.12602
更新日期:2017-04-01 00:00:00
abstract::Infiltration of surgical wounds with long-acting local anaesthetics (LA) is used to reduce postoperative incisional pain. We hypothesised that infiltration with LA interferes with wound healing in rats. Seventy-two rats were allocated into nine groups. After intraperitoneal anaesthesia, the interscapular dorsal region...
journal_title:International wound journal
pub_type: 杂志文章
doi:10.1111/j.1742-481X.2012.01101.x
更新日期:2014-08-01 00:00:00
abstract::Wound chronification and opportunistic infections stand as major factors leading to lower extremities amputations in diabetes. The molecular mechanisms underlying diabetic's torpid healing have not been elucidated. We present the case of a female diabetic patient that after a plantar abscess surgical drainage, tight g...
journal_title:International wound journal
pub_type: 杂志文章
doi:10.1111/j.1742-481X.2012.12000.x
更新日期:2013-04-01 00:00:00
abstract::Marjolin's ulcer refers to malignant degeneration in a chronic wound. Although originally described in an area of burns scar, many other chronic wounds such as osteomyelitis sinus tracts, venous stasis ulcers and chronic pressure sores have the potential to undergo malignant transformation. We present an interesting c...
journal_title:International wound journal
pub_type: 杂志文章
doi:10.1111/j.1742-481X.2011.00831.x
更新日期:2011-10-01 00:00:00
abstract::The World Health Assembly declared 2020, the International Year of the Nurse and the Midwife. Recent editorials and commentaries support the leading role of nurses and midwives as frontline caregivers emphasizing the need to invest in the nursing workforce worldwide to meet global health needs. Today nurses are also l...
journal_title:International wound journal
pub_type: 杂志文章
doi:10.1111/iwj.13492
更新日期:2020-12-01 00:00:00
abstract::Enzymatic debridement with collagenase is a technique that is commonly used in clinical practice. This systematic review examines the effect of collagenase on all kinds of wounds, compared to an alternative therapy, on wound healing, wound bed characteristics, cost-effectiveness and the occurrence of adverse events. W...
journal_title:International wound journal
pub_type: 杂志文章,meta分析,评审
doi:10.1111/iwj.12760
更新日期:2017-12-01 00:00:00
abstract::For the past 20 years, super-oxidised solutions (SOSs) have been shown to be potent antimicrobials and disinfectants via oxidative damage. However, the potential toxicity of SOSs on eukaryotic cells has not been documented in vitro. This is relevant because oxygen and chlorine reactive species may possibly induce agei...
journal_title:International wound journal
pub_type: 杂志文章
doi:10.1111/j.1742-481X.2007.00331.x
更新日期:2007-09-01 00:00:00
abstract::Biological alternatives to synthetic meshes are increasingly utilised in complex abdominal wall reconstruction. There is a lack of evidence demonstrating that non-cross-linked porcine acellular dermal matrix vascularizes and integrates with human tissue in suboptimal wound conditions. We aimed to evaluate these proper...
journal_title:International wound journal
pub_type: 杂志文章,评审
doi:10.1111/iwj.12558
更新日期:2016-10-01 00:00:00
abstract::The initial care of burn wounds and choice of dressing are pivotal to optimally support the healing process. To ensure fast re-epithelialisation within 10-14 days and prevent complications, an optimal healing environment is essential. An innovative dressing based on nanocellulose was used for the treatment of burns in...
journal_title:International wound journal
pub_type: 杂志文章
doi:10.1111/iwj.13548
更新日期:2021-01-19 00:00:00
abstract::Pathogenic, opportunistic, and commensal bacterial coexist in the intestinal tract, and imbalances among these strains have been linked to systemic inflammation and a variety of disease states. Similarly, human skin plays an important role as an interface between the body and the environment with an estimated 1 billio...
journal_title:International wound journal
pub_type: 杂志文章
doi:10.1111/iwj.13451
更新日期:2020-12-01 00:00:00
abstract::The aim of this study was to gain a better understanding of the venous leg ulcer (VLU) management in primary health care settings located in Melbourne metropolitan and rural Victoria, Australia. We explored health professionals' perspective on the use of the Australian and New Zealand Venous Leg Ulcer Clinical Practic...
journal_title:International wound journal
pub_type: 杂志文章
doi:10.1111/iwj.13334
更新日期:2020-06-01 00:00:00
abstract::A 6-month-old Caucasian baby is described with a postaxial polydactyly of the letf foot. Radiographic examination revealed the accessory digit was composed of soft tissue, some with a tiny osseous element, originated from around the metatarsophalangeal joint, defined by floating type (FT). The parents had consistent d...
journal_title:International wound journal
pub_type: 杂志文章
doi:10.1111/iwj.12700
更新日期:2017-10-01 00:00:00
abstract::Although platelet gel is considered one of the most popular tools in the treatment of chronic ulcers, current consensus on its use is not unanimous. A prospective randomised trial was carried out at the Plastic Surgery Unit of the 'Salvatore Maugeri' Foundation Hospital of Pavia (Italy). The study involved 13 patients...
journal_title:International wound journal
pub_type: 杂志文章,随机对照试验
doi:10.1111/j.1742-481X.2010.00671.x
更新日期:2010-06-01 00:00:00
abstract::Mohs micrographic surgery is the best therapeutical option for hand squamous cell carcinoma without bone involvement; however, the reconstruction of the surgical defect could be very difficult if the tumour is located in the distal phalanx of a finger. We present the case of a patient with a squamous cell carcinoma of...
journal_title:International wound journal
pub_type:
doi:10.1111/iwj.12979
更新日期:2019-06-01 00:00:00
abstract::Pressure injuries are one of the most common and costly complications occurring in US hospitals. With up to 3 million patients affected each year, hospital-acquired pressure injuries (HAPIs) place a substantial burden on the US healthcare system. In the current study, US hospital discharge records from 9.6 million pat...
journal_title:International wound journal
pub_type: 杂志文章
doi:10.1111/iwj.13482
更新日期:2020-12-01 00:00:00