Primary lymphoma of bone: experience of 39 cases at the Tata Memorial Hospital, India.

Abstract:

:Primary lymphoma of bone (PLB) is an uncommon clinical entity and a rare presentation of non-Hodgkin's lymphoma. At the Tata Memorial Hospital, over a period of 10 years from 1976 to 1985, 39 cases with a diagnosis of PLB were seen. Twenty-seven cases completed the prescribed treatment and were evaluable for treatment response. Eight patients (21%) presented in clinical stage I (E), four patients (10%) in stage II (E), and 27 patients (69%) in stage IV (E). All of the evaluable patients except two were treated with combination chemotherapy, which consisted of cyclophosphamide, vincristine, and prednisolone in 18 patients, and seven patients received Adriamycin in addition. The majority of patients received six courses of chemotherapy extending over 8 to 12 months. External radiotherapy was given to all except one patient, who had surgery as local treatment. Five patients had generalised relapse, one of which had in addition a local relapse. Five were resistant to treatment. Overall and disease-free survival by Kaplan-Meier method at 60 months are 66% and 56%, respectively.

journal_name

J Surg Oncol

authors

Susnerwala SS,Dinshaw KA,Pande SC,Shrivastava SK,Gonsalves MA,Advani SH,Gopal R

doi

10.1002/jso.2930440408

subject

Has Abstract

pub_date

1990-08-01 00:00:00

pages

229-33

issue

4

eissn

0022-4790

issn

1096-9098

journal_volume

44

pub_type

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