Abstract:
BACKGROUND:Cytoreductive surgery plus hyperthermic intraperitoneal chemotherapy (CS + HIPEC) is a treatment combining cytoreductive surgery with hyperthermic chemotherapy directly into the peritoneal cavity. Recipients may gain extended life when compared with best supportive care; yet results often are achieved with substantial morbidity and health-related quality of life (HRQOL) deficits. The purpose of this study was to record patient rated outcomes and the HRQOL of long-term survivors. METHODS:One hundred and two patients living 12+ months post-treatment completed a survey including the Medical Outcomes Study 36-item Short Form Health Survey (SF-36), Functional Assessment of Cancer Therapy-Colon (FACT-C), and Pittsburgh Sleep Quality Index. RESULTS:SF-36 Physical Component scores were significantly lower than general population norms (46.7, z= -2.943, P=0.003), while Mental Component scores were significantly higher (53.6, z=4.208, P ≤ 0.001). FACT scores were higher than general FACT normative scores. The majority (56%) of these survivors reported significant sleep quality impairment. CONCLUSION:Although most HRQOL scores were comparable to or higher than those of the general population, long-term physical and functional deficits remain. These deficits, along with the poor sleep quality of recipients, may be improved by survivorship programs or targeted psychosocial interventions.
journal_name
J Surg Oncoljournal_title
Journal of surgical oncologyauthors
Duckworth KE,McQuellon RP,Russell GB,Cashwell CS,Shen P,Stewart JH 4th,Levine EAdoi
10.1002/jso.23089subject
Has Abstractpub_date
2012-09-15 00:00:00pages
376-80issue
4eissn
0022-4790issn
1096-9098journal_volume
106pub_type
杂志文章abstract::Metastasis to the breast is uncommon, with an incidence of 0.5-3%. Alveolar soft part sarcoma is rare, accounting for < 1% of malignant soft tissue tumors, which are themselves unusual. Excluding contralateral breast and hematologic malignant disease, the primary lesion in most cases of metastasis to the breast is mel...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/(SICI)1096-9098(199602)61:2<159::AID-JSO13
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abstract::RLV-A serum activity was measured by the agar colony assay to determine the effect of this erythroid dyscrasia on the granulopoietic humoral regulator, colony stimulating factor (CSF). In general, the sera of early, midstage and terminal animals not given endotoxin had high cluster forming properties compared to norma...
journal_title:Journal of surgical oncology
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abstract::Upper extremity malignancies have the potential to create significant functional impairment, and as such represent an opportunity for collaborative reconstruction to minimize potential morbidity. Given the increased complexity and array of potential reconstruction solutions, functional limb preservation is overwhelmin...
journal_title:Journal of surgical oncology
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更新日期:2016-06-01 00:00:00
abstract::Giant cell tumor of bone is a challenging surgical problem due to its mostly aggressive growth with tendency to recur locally, to develop in rare instances pulmonary metastases without histologic evidence of malignant changes, and due to its potential to dedifferentiate into a frankly malignant tumor in a limited numb...
journal_title:Journal of surgical oncology
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更新日期:1994-12-01 00:00:00
abstract:OBJECTIVE:We retrospectively evaluated the impact of postoperative complications on long-term outcomes after curative resection for colorectal cancer (CRC), using propensity-score analysis (PSA). PATIENTS AND METHODS:We reviewed data from 673 consecutive patients with stage I to III CRC, who underwent curative resecti...
journal_title:Journal of surgical oncology
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abstract::Ten patients with Stage III-IV ovarian adenocarcinoma were treated with the drug combination etoposide (VP-16) plus cisplatin (DDP). All patients were in relapse following prior vigorous, uninterrupted treatment with three or more lines of chemotherapy that included (1) courses of weekly 1-mg/kg single-agent DDP, (2) ...
journal_title:Journal of surgical oncology
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abstract::"Taking less treating better" has been one of the major improvements of breast cancer surgery in the last four decades. The application of this principle translates into equivalent survival of breast cancer conserving treatment (BCT) when compared to mastectomy, with a better cosmetic outcome. While it is relatively e...
journal_title:Journal of surgical oncology
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abstract::About one third of leiomyosarcomas of the gastrointestinal tract do develop metastasis; and nearly 90% of the metastasis are intra-abdominal. It is said that leiomyosarcoma rarely involves regional nodes, although two series reported 8% of leiomyosarcomas of the stomach and 7% of the small intestines had nodal metasta...
journal_title:Journal of surgical oncology
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abstract:BACKGROUND AND OBJECTIVES:There have been few reports on the objective assessment of quality of life (QOL) in patients with gastric cancer following palliative operations. The benefit of a palliative operation for survival and QOL of patients with gastric cancer is not clear. METHODS:Survival and hospital-free surviva...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
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更新日期:1998-09-01 00:00:00
abstract::Tumor markers such as carcinoembryonic antigen (CEA) and CA19-9 were analyzed as response indicators and prognostic factors in advanced colorectal carcinoma. Eighty-five patients participated in a phase II chemotherapy study from October 1984 to July 1990. A three-drug schedule was administered including low dose epir...
journal_title:Journal of surgical oncology
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更新日期:1992-02-01 00:00:00
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journal_title:Journal of surgical oncology
pub_type: 杂志文章
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更新日期:2002-11-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:The median of pO2 values in tumor measured by Eppendorf "Histograph" with a needle-type electrode has been used as a prognostic indicator in cancer patients. However, it is not established that a pretreatment measured pO2 value can be used as a universal predictor of local control probability,...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/(sici)1096-9098(199709)66:1<30::aid-jso7>3
更新日期:1997-09-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Small lung adenocarcinomas are detected more frequently than in the past. However, the clinicopathologic characteristics and prognostic significance of EGFR/p53 mutations in these tumors remains unclear. METHODS:We evaluated the correlation of EGFR/p53 mutations with clinicopathologic charact...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.23628
更新日期:2014-08-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:To determine whether thyroid carcinoma in elderly patients presents any peculiar characteristics, whether the greater biological aggressiveness of the neoplasm modifies the surgical treatment selected, and whether age greater than 70 years represents an independent prognostic factor. METHODS:...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.20140
更新日期:2004-12-15 00:00:00
abstract::The Author describes criteria for selection of patients who might be eligible for entry into a clinical trial of definitive Radiation Therapy for adenocarcinoma of the pancreas. Most emphasis is placed on careful surgical staging, target volume and location, and the use of bypass procedures when appropriate. ...
journal_title:Journal of surgical oncology
pub_type: 临床试验,杂志文章
doi:10.1002/jso.2930070208
更新日期:1975-01-01 00:00:00
abstract:BACKGROUND:Preoperative prognostic information to select a treatment strategy is important especially in patients who need highly aggressive surgery, such as those with biliary cancer. We evaluated various prognostic factors and non-curative surgical factors using multidetector computed tomography (MDCT). METHODS:We r...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.21501
更新日期:2010-04-01 00:00:00
abstract::Several months (an average of 12.86 months) after perineal needling of the cancerous prostate for the purpose of obtaining tissue for biopsy, a tumor nodule becomes clinically evident in the subcutaneous tissue of the perineum, at the site of the needling in 0.34% of the cases. This nodule presents the same histologic...
journal_title:Journal of surgical oncology
pub_type: 杂志文章,评审
doi:10.1002/jso.2930350309
更新日期:1987-07-01 00:00:00
abstract:PURPOSE:The aims of the study were to estimate the frequency of epiphora and to identify factors associated with epiphora after orbital-sparing maxillectomy via modified Weber-Ferguson incision with lower blepharoplasty (OSOSM-MWFILB). METHODS:We performed a retrospective cohort study enrolling a sample derived from t...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.26408
更新日期:2021-02-01 00:00:00
abstract::Sentinel lymph node (sN) biopsy has gained special attention among surgical and medical oncologists as it represents an accepted technique for detecting occult nodal disease in regional lymph nodes of patients with melanoma and breast cancer. The histopathologic examination of the sN may well predict regional lymph no...
journal_title:Journal of surgical oncology
pub_type: 杂志文章,评审
doi:10.1002/jso.20031
更新日期:2004-03-01 00:00:00
abstract::To gauge the impact of screening mammography and opinions regarding surgical procedures on the pattern of primary surgical care of breast cancer, tumor registry statistics from 1980-81 were compared to those from 1987 at a large community hospital. Over the course of six years, there was a significant increase in the ...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930450104
更新日期:1990-09-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Accumulating epidemiological and molecular evidence suggests that inflammation is an important component in the etiology of PCa. Macrophage migration inhibitory factor (MIF) plays an important role in the pro- and anti-inflammatory response to infection. This study is aimed at investigating th...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.21304
更新日期:2009-08-01 00:00:00
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journal_title:Journal of surgical oncology
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doi:10.1002/jso.25454
更新日期:2019-07-01 00:00:00
abstract:BACKGROUND:Few studies describe quality of life (QoL) outcomes following gastrectomy for gastric cancer using a validated instrument. The gastric cancer module for the Functional Assessment of Cancer Therapy system of QoL measurement tools (FACT-Ga) was utilized to determine the changes in QoL following gastrectomy, an...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
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更新日期:2012-03-15 00:00:00
abstract:BACKGROUND:This study evaluates several tumor-related markers to examine the expression pattern of markers according to the invasiveness and histopathologic differentiation of squamous cell carcinoma and basal cell carcinoma. METHODS:Ninety-four cases of squamous cell carcinoma and 108 cases of basal cell carcinoma us...
journal_title:Journal of surgical oncology
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更新日期:2008-06-01 00:00:00
abstract:BACKGROUND:Proper tip position is a major determinant of totally implantable venous access device (TIVAD) outcome. The aim of this study is to analyze the potential utilization of intravenous electrocardiography (IV-ECG) to help inexperienced operators for TIVAD placement. PATIENTS AND METHODS:This is a retrospective,...
journal_title:Journal of surgical oncology
pub_type: 临床试验,杂志文章
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更新日期:2012-06-15 00:00:00
abstract:BACKGROUND:Somatostatin analog functional imaging with gallium-68 (Ga-68) dotatate positron emission tomography/computed tomography (PET/CT) has demonstrated superiority in lesion detection in patients with neuroendocrine tumors (NETs). The clinical impact of this imaging modality on US surgical and medical oncology pr...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
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更新日期:2020-03-01 00:00:00
abstract::Over the past decade, there has been a considerable increase in the utilization of cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) in the management of patients with peritoneal metastases. This is due to improved safety and favorable oncologic outcomes, including curative potential. C...
journal_title:Journal of surgical oncology
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更新日期:2020-07-01 00:00:00
abstract::Tumor-associated antigen(s) from a specimen of human malignant melanoma and from spent culture medium of a melanoma cell line were extracted and purified. The incidence of antibody activity to these antigens, in sera from cancer patients with neoplasms of various histologic types, was higher (65--83%) than normal dono...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930130112
更新日期:1980-01-01 00:00:00
abstract::We reviewed the records of 66 consecutive patients who underwent placement of totally implantable venous access devices (TIVADs). Fourteen patients (21%) experienced complications related to the TIVAD. Complications included hematoma, infection, pneumothorax, subclavian vein thrombosis, and chronic clavicular pain. Th...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
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更新日期:1990-05-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:The reported risk of nodal metastasis in hard palate and upper gingival squamous cell carcinoma (SCC) has been inconsistent with inadequate consensus regarding the utility of neck dissection in the clinically negative (cN0) neck. MATERIALS AND METHODS:Using the National Cancer Database, cN0 p...
journal_title:Journal of surgical oncology
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更新日期:2019-12-01 00:00:00