Abstract:
BACKGROUND AND OBJECTIVES:Sentinel node (SN) biopsy is a new standard of care for axillary node staging in patients with early-stage, clinically node-negative breast cancer. A second operation can be avoided when the results are available intraoperatively. However, there is no standard intraoperative method for SN assessment. The aim of this study was to evaluate intraoperative imprint cytology (IC) for the detection of SN involvement in patients with early-stage breast cancer. METHODS:One hundred eighty-five consecutive patients with a breast tumor underwent SN biopsy with intraoperative IC. The SN was bisected and a touch preparation was made with a glass slide, on both sides of the cut. Permanent sections were evaluated with H&E and immunohistochemical staining. The IC results were compared with the final histologic results. RESULTS:The sensitivity, specificity, accuracy, and positive and negative predictive values of IC were 33.3, 78.4, 78.9, 90, and 77.5%, respectively. IC was more sensitive for macrometastases than for micrometastases. In the 118 patients studied after the learning phase, 9 patients with a positive SN by IC avoided a second operation. CONCLUSIONS:Intraoperative IC of SNs appears to be reasonably reliable in patients with breast cancer, permitting axillary dissection during the same surgical procedure when positive. In contrast, sensitivity for detection of micrometastases is low.
journal_name
J Surg Oncoljournal_title
Journal of surgical oncologyauthors
Barranger E,Antoine M,Grahek D,Callard P,Uzan Sdoi
10.1002/jso.20067subject
Has Abstractpub_date
2004-06-01 00:00:00pages
128-33issue
3eissn
0022-4790issn
1096-9098journal_volume
86pub_type
杂志文章,评审abstract::A massive lymphatic leak developed following radical retroperitoneal lymph node dissection for recurrent extragonadal seminoma. Chylous ascites persisted for over 3 months, with an average daily external drainage of 1.5 liters, and was successfully treated with a peritoneovenous shunt. ...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930360315
更新日期:1987-11-01 00:00:00
abstract:BACKGROUND:Some cases of mass-forming intrahepatic cholangiocarcinoma (ICC) are diagnosed as hepatocellular carcinoma (HCC) based on preoperative imaging and clinical findings. We investigated the backgrounds of such cases. METHODS:Sixty-seven patients with mass-forming ICC underwent surgery from 1980 to 2002. Twenty-...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.20091
更新日期:2004-08-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Blue nevi are benign pigmented dermal lesions that can mimic cutaneous melanoma in appearance. Cellular components may infiltrate subcutaneous tissue. We present a complex case of cellular blue nevus (CBN) to demonstrate the ambiguous clinical appearance of these lesions and to provide an appr...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/1096-9098(200008)74:4<278::aid-jso7>3.0.co
更新日期:2000-08-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:When performed at select centers, minimally invasive gastrectomy (MIG) for gastric adenocarcinoma is associated with reduced perioperative morbidity, and similar oncologic outcomes as compared to open gastrectomy (OG). Utilization of, and outcomes associated with, MIG in the United States have...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.24052
更新日期:2015-11-01 00:00:00
abstract:BACKGROUND:CD109, a TGF-β co-receptor, is reported to be preferentially expressed during the early stages of tumorigenesis in several carcinoma types. Myxofibrosarcoma is one of the most common soft-tissue sarcomas found in elderly patients. This study aimed to elucidate the impact of CD109 expression in myxofibrosarco...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.23934
更新日期:2015-06-01 00:00:00
abstract::Adenocarcinomas of the trachea are rare but important because the only reported treatment in the past (radiation) has resulted in uniformly poor results. The authors recently had the opportunity to treat a young woman with a mucin-producing adenocarcinoma of the trachea. A sleeve resection of the involved trachea with...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930280108
更新日期:1985-01-01 00:00:00
abstract::To clarify the role of neural cell adhesion molecule (NCAM) in perineural invasion, NCAM expression was studied by immunohistochemical staining in 26 cases with gallbladder cancer. In gallbladder cancer, the incidence of perineural invasion and that of positive NCAM expression was 42% and 31%, respectively, which are ...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930580205
更新日期:1995-02-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Surgical procedures can cause tumor cells to disseminate into the circulatory system. Although this spread of metastatic cells will be limited by immune activity, immunosuppression tends to be the main effect resulting from surgery. The objective of this study is to assess hormonal and immunol...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.21662
更新日期:2010-11-01 00:00:00
abstract::Palliative care (PC) seeks to improve the quality of life for patients facing serious illness. Several oncology organizations have guidelines about PC, reflecting the need to integrate PC into standard oncology care. Many surgical patients do not receive PC despite the need for these services and established surgical ...
journal_title:Journal of surgical oncology
pub_type: 杂志文章,评审
doi:10.1002/jso.25449
更新日期:2019-07-01 00:00:00
abstract:BACKGROUND:Recurrent adrenocortical carcinoma (ACC) has a poor prognosis with minimal clinical and biochemical factors to guide management. The aim of this study was to evaluate the prognostic significance of systemic inflammatory response in patients with recurrent ACC. METHODS:Patients who underwent resection for re...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.25760
更新日期:2019-12-01 00:00:00
abstract:OBJECTIVES:To identify the prognostic implications of human papillomavirus (HPV)-related cell cycle marker profiles in patients who have received a transoral lateral oropharyngectomy (TLO) as a primary treatment for tonsillar squamous cell carcinoma (TSCC). PATIENTS AND METHODS:Immunohistochemical profiles of HPV-rela...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.23672
更新日期:2014-09-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:B7-H4 is a novel molecular B7 ligand that plays an important role as a negative regulator of the T cell-mediated immune response. However, the clinical significance of B7-H4 expression in gastric cancer remains uncertain. Here, we assessed B7-H4 expression in blood of patients with gastric can...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.21722
更新日期:2010-12-01 00:00:00
abstract::Intrapancreatic extension of pancreatic duct cell carcinoma in 19 resectable cases was evaluated by both hematoxylin and eosin (H&E) staining and quick immunostaining using antibodies against cancer-associated antigens--e.g., CA19-9, DUPAN 2, and CEA--on the intraoperative frozen-section biopsy during the course of la...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930400105
更新日期:1989-01-01 00:00:00
abstract:INTRODUCTION:The Siewert classification has been used to plan treatment for tumours of the gastro-oesophageal junction since its proposal in the 1980s. The purpose of this study was to assess its continued relevance by evaluating whether there were differences in the biology and clinical characteristics of adenocarcino...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.23484
更新日期:2014-03-01 00:00:00
abstract::The present study has investigated whether Kaposi's sarcoma (KS) in Nigeria is associated with infection with the AIDS virus variously called human T-cell lymphotropic virus type III (HTLV-III), lymphadenopathy/AIDS virus (LAV), and AIDS-associated retrovirus (ARV). Serum samples from 40 KS patients, 30 patients with ...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930370303
更新日期:1988-03-01 00:00:00
abstract::A retrospective analysis was performed of 20 patients with Ewing's sarcoma treated by combined modality therapy, consisting of surgery, radiotherapy, and chemotherapy. Fourteen patients (70%) achieved complete remission and 5 patients (25%) were in partial remission at the end of treatment. One patient (5%) failed to ...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930480110
更新日期:1991-09-01 00:00:00
abstract:BACKGROUND:The aim of this study is to describe the influence of geography, socio-economic development, and demographic shift on the trends in global incidence, mortality, and prevalence of liver cancer (LC). METHODS:Data (2012-2030) relating to LC and demographic shifts based on WHO regions and HDI areas were extract...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.24518
更新日期:2017-04-01 00:00:00
abstract:INTRODUCTION:The need for regional lymphadenectomy for treating appendiceal neuroendocrine tumors (A-NET) is determined by the risk of nodal metastasis. Current guidelines for A-NET are solely based on tumor size. Methods Patients with A-NET from 1988 to 2012 were identified from the SEER registry. The depth of invasio...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.24714
更新日期:2017-11-01 00:00:00
abstract::A primary retroperitoneal dermoid cyst (benign cystic teratoma) is described in a 64-year-old male, who died postoperatively of a leaking grafted abdominal aortic aneurysm. The asymptomatic tumor, measuring 12 cm in greatest diameter, showed an extensive sclerosing lipogranulomatous reaction in its wall and wide-sprea...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930140102
更新日期:1980-01-01 00:00:00
abstract::A single-row suturing anastomosis (SRA) for an esophagogastrostomy was experimentally investigated in dogs. SRA not only shortened operating time, but also led to better pathological results when compared with double-row suturing anastomosis. Wide-brim suturing and equal distance between the sutures, providing increas...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930430309
更新日期:1990-03-01 00:00:00
abstract:BACKGROUND:Based on the promising results of EAP (etoposide, doxorubicin, and cisplatin) combination, a phase II study of modified EAP combination was performed in patients with advanced gastric cancer to evaluate the response, toxicity, and survival. METHOD:Fifty-two consecutive patients with measurable or evaluable ...
journal_title:Journal of surgical oncology
pub_type: 临床试验,杂志文章
doi:10.1002/(sici)1096-9098(199704)64:4<318::aid-jso13
更新日期:1997-04-01 00:00:00
abstract:UNLABELLED:Thirty-three patients with primary gastrointestinal lymphoma (GIL) followed at Ankara University Medical School have been evaluated. The most frequent locations of the disease are the small intestine (48.4%) and the stomach (39.3%). The intermediate and high grade lymphomas constitute 84.8% of the cases. The...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930510414
更新日期:1992-12-01 00:00:00
abstract::As patients with ovarian cancer are living longer, surgeons will be faced with the management of metastatic lesions amenable to resection more frequently. We present two patients with ovarian cancer metastatic to the breast who underwent resection for their metastases, but their outcomes differed significantly. After ...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.24055
更新日期:2015-11-01 00:00:00
abstract::Australia has the world's highest incidence of skin cancer. Despite excellent prevention and early diagnosis education programs and an increasing percentage of the population with darker and more UV tolerant skins, skin cancer remains a major and expensive community medical problem. However, primary and secondary prev...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.20086
更新日期:2004-07-01 00:00:00
abstract::A specific red cell adhesion test was done in 243 patients with carcinoma of the cervix uteri and showed the presence of isoantigens in only 27.16% of the patients with infiltrating squamous cell carcinoma. There was a gradual loss of isoantigens during the development of carcinoma. The test can be usefully employed i...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.2930160111
更新日期:1981-01-01 00:00:00
abstract:PURPOSE:To describe venous thromboembolism (VTE) rates in patients with pancreatic cancer (PC) during neoadjuvant therapy. METHODS:Factors associated with VTE were evaluated using multivariable logistic regression modeling in patients with resectable and BLR PC treated with neoadjuvant therapy between 2009 and 2014. ...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.24361
更新日期:2016-10-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Variants of CD44 have been proposed to be important in promoting tumor progression and metastasis. We attempted to determine the expression of CD44v6 product in advanced gastric cancer and to evaluate its prognostic value. METHODS:The expression of CD44v6 was analyzed immunohistochemically in...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.10082
更新日期:2002-04-01 00:00:00
abstract:PURPOSE:Imatinib mesylate (IM) demonstrates substantial efficacy in most patients with metastatic gastrointestinal stromal tumors (GISTs). However, progression of GIST eventually develops and emerges as a challenge. To assess the role of surgery in the multidisciplinary management of GISTs, we studied the surgical outc...
journal_title:Journal of surgical oncology
pub_type: 杂志文章
doi:10.1002/jso.21630
更新日期:2010-11-01 00:00:00
abstract::Locally recurrent cancer of the rectum has been under-recognized as a complication, although it affects up to 40% of patients treated with surgery alone. Even in the best centers, rates average 25%. While radiotherapy may reduce recurrence, it is now apparent that total mesorectal excision is the most effective modali...
journal_title:Journal of surgical oncology
pub_type: 杂志文章,评审
doi:10.1002/(sici)1096-9098(200001)73:1<47::aid-jso12>
更新日期:2000-01-01 00:00:00
abstract::Retroperitoneal sarcomas (RPS) have fascinated and intrigued physicians both past and present. Operative mortality rates were historically very high and complete resection was not possible for the majority of patients until only the last 2 decades. More recently, changes to the surgical approach and clinical decision-...
journal_title:Journal of surgical oncology
pub_type: 历史文章,杂志文章,评审
doi:10.1002/jso.24888
更新日期:2018-01-01 00:00:00