Early assessment of breast cancer response to neoadjuvant chemotherapy by semi-quantitative analysis of high-temporal resolution DCE-MRI: preliminary results.

Abstract:

PURPOSE:To evaluate whether semi-quantitative analysis of high temporal resolution dynamic contrast-enhanced MRI (DCE-MRI) acquired early in treatment can predict the response of locally advanced breast cancer (LABC) to neoadjuvant chemotherapy (NAC). MATERIALS AND METHODS:As part of an IRB-approved prospective study, 21 patients with LABC provided informed consent and underwent high temporal resolution 3T DCE-MRI before and after 1cycle of NAC. Using measurements performed by two radiologists, the following parameters were extracted for lesions at both examinations: lesion size (short and long axes, in both early and late phases of enhancement), radiologist's subjective assessment of lesion enhancement, and percentages of voxels within the lesion demonstrating progressive, plateau, or washout kinetics. The latter data were calculated using two filters, one selecting for voxels enhancing ≥50% over baseline and one for voxels enhancing ≥100% over baseline. Pretreatment imaging parameters and parameter changes following cycle 1 of NAC were evaluated for their ability to discriminate patients with an eventual pathological complete response (pCR). RESULTS:All 21 patients completed NAC followed by surgery, with 9 patients achieving a pCR. No pretreatment imaging parameters were predictive of pCR. However, change after cycle 1 of NAC in percentage of voxels demonstrating washout kinetics with a 100% enhancement filter discriminated patients with an eventual pCR with an area under the receiver operating characteristic curve (AUC) of 0.77. Changes in other parameters, including lesion size, did not predict pCR. CONCLUSION:Semi-quantitative analysis of high temporal resolution DCE-MRI in patients with LABC can discriminate patients with an eventual pCR after one cycle of NAC.

journal_name

Magn Reson Imaging

authors

Abramson RG,Li X,Hoyt TL,Su PF,Arlinghaus LR,Wilson KJ,Abramson VG,Chakravarthy AB,Yankeelov TE

doi

10.1016/j.mri.2013.07.002

subject

Has Abstract

pub_date

2013-11-01 00:00:00

pages

1457-64

issue

9

eissn

0730-725X

issn

1873-5894

pii

S0730-725X(13)00233-6

journal_volume

31

pub_type

临床试验,杂志文章
  • Analysis of time reduction methods for magnetic resonance elastography of the brain.

    abstract::Magnetic resonance elastography (MRE) uses a phase-contrast MRI technique to image shear wave propagation in tissue followed by the mathematical inversion of the equations of motion governing tissue mechanics to noninvasively image tissue stiffness. This work investigates the impact of various MR sampling strategies d...

    journal_title:Magnetic resonance imaging

    pub_type: 杂志文章

    doi:10.1016/j.mri.2010.06.016

    authors: Murphy MC,Glaser KJ,Manduca A,Felmlee JP,Huston J 3rd,Ehman RL

    更新日期:2010-12-01 00:00:00

  • Effects of apodization smoothing and denoising on spectral fitting.

    abstract:PURPOSE:Visual review of individual spectra in magnetic resonance spectroscopic imaging (MRSI) data benefits from the application of spectral smoothing; however, if this processing step is applied prior to spectral analysis this can impact the accuracy of the quantitation. This study aims to analyze the effect of spect...

    journal_title:Magnetic resonance imaging

    pub_type: 杂志文章

    doi:10.1016/j.mri.2020.04.013

    authors: Goryawala M,Sullivan M,Maudsley AA

    更新日期:2020-07-01 00:00:00

  • Quantitation of normal canine hippocampus formation volume: correlation of MRI with gross histology.

    abstract::The hippocampal formation possesses an important role in the development and maintenance of short-term memory. In this study, magnetic resonance imaging (MRI) and gross histology were used to quantify the volume of the hippocampal formation in canines. High resolution MRI, using 1 mm thick slices and an intraplanar re...

    journal_title:Magnetic resonance imaging

    pub_type: 杂志文章

    doi:10.1016/0730-725x(95)02083-6

    authors: Vullo T,Deo-Narine V,Stallmeyer MJ,Gomez DG,Cahill PT

    更新日期:1996-01-01 00:00:00

  • Imaging of HDR brachytherapy dose distributions using NMR Fricke-gelatin dosimetry.

    abstract::The application of NMR Fricke-gelatin dosimetry to the imaging of dose distributions around high dose rate (HDR) radioactive Ir-192 seeds in brachytherapy is presented. The duration of the irradiations required to give changes of the Fricke-gelatin NMR characteristics, which were readily detected by the magnetic reson...

    journal_title:Magnetic resonance imaging

    pub_type: 杂志文章

    doi:10.1016/0730-725x(94)92031-1

    authors: Schreiner LJ,Crooks I,Evans MD,Keller BM,Parker WA

    更新日期:1994-01-01 00:00:00

  • 4D MR phase and magnitude segmentations with GPU parallel computing.

    abstract::The increasing size and number of data sets of large four dimensional (three spatial, one temporal) magnetic resonance (MR) cardiac images necessitates efficient segmentation algorithms. Analysis of phase-contrast MR images yields cardiac flow information which can be manipulated to produce accurate segmentations of t...

    journal_title:Magnetic resonance imaging

    pub_type: 杂志文章

    doi:10.1016/j.mri.2014.08.019

    authors: Bergen RV,Lin HY,Alexander ME,Bidinosti CP

    更新日期:2015-01-01 00:00:00

  • In vivo temporal EPR imaging of the brain of rats by using two types of blood-brain barrier-permeable nitroxide radicals.

    abstract::In vivo temporal EPR imaging was conducted on the brain of rats that received one of two kinds of blood-brain barrier-permeable nitroxide radicals via the tail vein-one is a water-soluble 3-hydroxymethyl-2,2,5,5-tetramethylpyrrolidine-1-oxyl (hydroxymethyl-PROXYL); and the other is a non-water-soluble 3-methoxycarbony...

    journal_title:Magnetic resonance imaging

    pub_type: 杂志文章

    doi:10.1016/s0730-725x(02)00491-5

    authors: Yokoyama H,Itoh O,Aoyama M,Obara H,Ohya H,Kamada H

    更新日期:2002-04-01 00:00:00

  • Effects of 3D sampling in (k, t)-space on temporal qualities of dynamic MRI.

    abstract::3D (kx, ky, t)-space analysis is invoked to provide insights into dynamic magnetic resonance imaging (DMRI) with arbitrary k-space sampling trajectories. The effects of 3D sampling in (kx, ky, t) are analyzed theoretically and verified with computer simulation. The analyses show that a 3D sampling pattern that is more...

    journal_title:Magnetic resonance imaging

    pub_type: 杂志文章

    doi:10.1016/j.mri.2006.04.009

    authors: Park JB,Nishimura DG

    更新日期:2006-10-01 00:00:00

  • An intravascular loopless monopole antenna for vessel wall MR imaging at 3.0 T.

    abstract::The purpose of this study was to develop a novel intravascular loopless monopole antenna (ILMA) design specifically for imaging of small vessel walls. The ILMA consisted of an unshielded, low-friction guide wire and a tuning/matching box. The material of the guide wire was nitinol and it was coated with polyurethane. ...

    journal_title:Magnetic resonance imaging

    pub_type: 杂志文章

    doi:10.1016/j.mri.2012.06.032

    authors: Yuan H,Lv X,Ma X,Zhang R,Fu Y,Yang X,Wang X,Zhang Z,Zhang J,Fang J

    更新日期:2013-01-01 00:00:00

  • Effect of physiological heart rate variability on quantitative T2 measurement with ECG-gated Fast Spin Echo (FSE) sequence and its retrospective correction.

    abstract:OBJECT:Quantitative T2 measurement is applied in cardiac Magnetic Resonance Imaging (MRI) for the diagnosis and follow-up of myocardial pathologies. Standard Electrocardiogram (ECG)-gated fast spin echo pulse sequences can be used clinically for T2 assessment, with multiple breath-holds. However, heart rate is subject ...

    journal_title:Magnetic resonance imaging

    pub_type: 杂志文章

    doi:10.1016/j.mri.2013.06.006

    authors: de Roquefeuil M,Vuissoz PA,Escanyé JM,Felblinger J

    更新日期:2013-11-01 00:00:00

  • A spectroscopic NMR investigation of the calcium silicate hydrates present in cement and concrete.

    abstract::NMR spectroscopy is applied to study microstructure of calcium silicate hydrates present in cement and concrete. It is shown that 29Si NMR gives information on the siliceous skeleton of the hydrates. 1H NMR, using CRAMPS techniques, allows to discriminate between protons linked to silicon atoms or to calcium atoms. A ...

    journal_title:Magnetic resonance imaging

    pub_type: 杂志文章

    doi:10.1016/s0730-725x(96)00211-1

    authors: Zanni H,Rassem-Bertolo R,Masse S,Fernandez L,Nieto P,Bresson B

    更新日期:1996-01-01 00:00:00

  • Dose distribution of proton beams with NMR measurements of Fricke-agarose gels.

    abstract::Fricke-agarose gels have been irradiated with a proton beam. Then samples have been extracted at different depths with respect to the beam penetration distance, corresponding to different irradiation doses. Relaxation times T1 and T2, measured at 17 MHz, appear sensitive to this kind of radiation. In particular, T2 ex...

    journal_title:Magnetic resonance imaging

    pub_type: 杂志文章

    doi:10.1016/s0730-725x(96)00380-3

    authors: Di Capua S,D'Errico F,Egger E,Guidoni L,Luciani AM,Rosi A,Viti V

    更新日期:1997-01-01 00:00:00

  • Non-contrast MR Lymphography of lipedema of the lower extremities.

    abstract:AIM:To assess imaging findings and characteristics of the lymphatic system in patients affected by lipedema and lipolymphedema of the lower extremities on Non-Contrast MR Lymphography (NCMRL). MATERIALS AND METHODS:44 lower extremities in 11 consecutive female patients affected by lipedema, and 11 patients with lipoly...

    journal_title:Magnetic resonance imaging

    pub_type: 杂志文章

    doi:10.1016/j.mri.2020.06.010

    authors: Cellina M,Gibelli D,Soresina M,Menozzi A,Martinenghi C,Panzeri M,Oliva G

    更新日期:2020-09-01 00:00:00

  • Voxelwise analysis of diffusion MRI of cervical spinal cord using tract-based spatial statistics.

    abstract::Robust voxelwise analysis using tract-based spatial statistics (TBSS) together with permutation statistical method is standardly used in analyzing diffusion tensor imaging (DTI) of brain. A similar analytical method could be useful when studying DTI of cervical spinal cord. Based on anatomical data of sixty-four healt...

    journal_title:Magnetic resonance imaging

    pub_type: 杂志文章

    doi:10.1016/j.mri.2020.07.008

    authors: Dostál M,Keřkovský M,Staffa E,Bednařík J,Šprláková-Puková A,Mechl M

    更新日期:2020-11-01 00:00:00

  • Theoretical considerations in measurement of time discrepancies between input and myocardial time-signal intensity curves in estimates of regional myocardial perfusion with first-pass contrast-enhanced MRI.

    abstract::The purpose of this study was to develop a method to determine time discrepancies between input and myocardial time-signal intensity (TSI) curves for accurate estimation of myocardial perfusion with first-pass contrast-enhanced MRI. Estimation of myocardial perfusion with contrast-enhanced MRI using kinetic models req...

    journal_title:Magnetic resonance imaging

    pub_type: 杂志文章

    doi:10.1016/j.mri.2015.06.015

    authors: Natsume T,Ishida M,Kitagawa K,Nagata M,Sakuma H,Ichihara T

    更新日期:2015-11-01 00:00:00

  • Effect of ovariectomy on contrast agent diffusion into lumbar intervertebral disc: a dynamic contrast-enhanced MRI study in female rats.

    abstract:PURPOSE:The purpose was to study the effect of estrogen deficiency on contrast agent diffusion into intervertebral disc in a rat model. MATERIALS AND METHODS:Seven-month-old female Sprague-Dawley rats were used. Fourteen rats had ovariectomy, and nine rats had sham surgery. Magnetic resonance imaging (MRI) of sagittal...

    journal_title:Magnetic resonance imaging

    pub_type: 杂志文章

    doi:10.1016/j.mri.2012.01.001

    authors: Deng M,Griffith JF,Zhu XM,Poon WS,Ahuja AT,Wang YX

    更新日期:2012-06-01 00:00:00

  • Diffusion of water in industrial cement and concrete.

    abstract::We propose a deuterium diffusion tracer approach to measure diffusion coefficient in the case of very short NMR relaxation times, too short for NMR pulsed field gradient sequences (T1 or T2 below 1 ms). We also treat the case of porous media containing metallic fibers (such as reinforced concrete) strongly disturbing ...

    journal_title:Magnetic resonance imaging

    pub_type: 杂志文章

    doi:10.1016/j.mri.2018.09.010

    authors: Fleury M,Berthe G,Chevalier T

    更新日期:2019-02-01 00:00:00

  • Automated segmentation of lateral ventricles from human and primate magnetic resonance images using cognition network technology.

    abstract::Automatic segmentation of different types of tissue from magnetic resonance images is of great importance for clinical and research applications, particularly large-scale and longitudinal studies of brain pathology. We developed a fully automated algorithm for the segmentation of lateral ventricles from cranial magnet...

    journal_title:Magnetic resonance imaging

    pub_type: 杂志文章

    doi:10.1016/j.mri.2006.08.013

    authors: Schönmeyer R,Prvulovic D,Rotarska-Jagiela A,Haenschel C,Linden DE

    更新日期:2006-12-01 00:00:00

  • Test-retest reliability of cerebral blood flow in healthy individuals using arterial spin labeling: Findings from the EMBARC study.

    abstract:INTRODUCTION:Previous investigations of test-retest reliability of cerebral blood flow (CBF) at rest measured with pseudo-continuous Arterial Spin Labeling (pCASL) demonstrated good reliability, but are limited by the use of similar scanner platforms. In the present study we examined test-retest reliability of CBF in r...

    journal_title:Magnetic resonance imaging

    pub_type: 杂志文章

    doi:10.1016/j.mri.2017.09.004

    authors: Almeida JRC,Greenberg T,Lu H,Chase HW,Fournier JC,Cooper CM,Deckersbach T,Adams P,Carmody T,Fava M,Kurian B,McGrath PJ,McInnis MG,Oquendo MA,Parsey R,Weissman M,Trivedi M,Phillips ML

    更新日期:2018-01-01 00:00:00

  • In vivo magnetic resonance study of the histochemistry of coconut (Cocos nucifera).

    abstract::Magnetic resonance imaging (MRI) and localized proton MR spectroscopy (MRS) techniques have been applied for studying different maturation processes in the histochemistry of coconut (Cocos nucifera). Images of the tender and mature coconut are characterized by protons of the aqueous solution present in the cavity and ...

    journal_title:Magnetic resonance imaging

    pub_type: 杂志文章

    doi:10.1016/0730-725x(95)00033-d

    authors: Jagannathan NR,Govindaraju V,Raghunathan P

    更新日期:1995-01-01 00:00:00

  • Management of branch-duct intraductal papillary mucinous neoplasms of the pancreas: observation with MR imaging.

    abstract:PURPOSE:To evaluate the clinical outcomes of conservative management by observation with MRI of patients with branch-duct intraductal papillary mucinous neoplasms (BD-IPMNs). MATERIALS AND METHODS:Twenty-three consecutive patients, who were followed up by MRI with magnetic resonance cholangiopancreatography (MRCP) ove...

    journal_title:Magnetic resonance imaging

    pub_type: 杂志文章

    doi:10.1016/j.mri.2010.06.026

    authors: Shin SS,Armao DM,Shah M,Kim YH,Lee CH,Rubinas T,Brubaker LM,Semelka RC

    更新日期:2010-12-01 00:00:00

  • Simple phase method for measurement of magnetic field gradient waveforms.

    abstract::Magnetic field gradients play a fundamental role in MR imaging and localized spectroscopy. The MRI experiment, in particular fast MRI, relies on precise gradient switching, which has become more demanding with the constantly growing number of fast imaging techniques. Here we present a simple MR method to measure the b...

    journal_title:Magnetic resonance imaging

    pub_type: 杂志文章

    doi:10.1016/j.mri.2007.02.002

    authors: Latta P,Gruwel ML,Volotovskyy V,Weber MH,Tomanek B

    更新日期:2007-11-01 00:00:00

  • A purpose-built neck coil for black-blood DANTE-prepared carotid artery imaging at 7T.

    abstract::Atherosclerotic plaques in the bifurcation of the carotid arteries can pose a significant health risk due to possible plaque rupture and subsequent stroke. The assessment of plaques, and evaluation of the risk they pose, can be performed with Black-Blood (BB) vessel wall magnetic resonance imaging. However, resolution...

    journal_title:Magnetic resonance imaging

    pub_type: 杂志文章

    doi:10.1016/j.mri.2017.04.011

    authors: Papoutsis K,Li L,Near J,Payne S,Jezzard P

    更新日期:2017-07-01 00:00:00

  • A comprehensive approach to studies of porous media (rocks) using a laboratory spectrometer and logging tool with similar operating characteristics.

    abstract::The value of NMR spectrometry as a way to understand the porosity and permeability of rocks is well documented. Other more esoteric parameters, such as restrictive diffusion, grain size distribution, and fluid viscosities have received less notice but are also available from the NMR measurements as laboratory studies ...

    journal_title:Magnetic resonance imaging

    pub_type: 杂志文章

    doi:10.1016/0730-725x(94)91537-7

    authors: Taicher Z,Coates G,Gitartz Y,Berman L

    更新日期:1994-01-01 00:00:00

  • Free-running simultaneous myocardial T1/T2 mapping and cine imaging with 3D whole-heart coverage and isotropic spatial resolution.

    abstract:PURPOSE:To develop a free-running framework for 3D isotropic simultaneous myocardial T1/T2 mapping and cine imaging. METHODS:Continuous data acquisition with 3D golden angle radial trajectory is used in conjunction with T2 preparation of varying echo times and inversion recovery (IR) pulses to enable simultaneous myoc...

    journal_title:Magnetic resonance imaging

    pub_type: 杂志文章

    doi:10.1016/j.mri.2019.08.008

    authors: Qi H,Bustin A,Cruz G,Jaubert O,Chen H,Botnar RM,Prieto C

    更新日期:2019-11-01 00:00:00

  • Biliary cystadenocarcinoma: seven year follow-up and the role of MRI and MRCP.

    abstract::Biliary cystadenomas and their malignant counterparts, biliary cystadenocarcinomas, are rare cystic tumors that arise from hepatobiliary epithelium. Ultrasound (US) and computed tomography (CT) are the initial imaging modalities used for the evaluation of biliary cystic tumors, but are not specific. MRI and MRCP, beca...

    journal_title:Magnetic resonance imaging

    pub_type: 杂志文章

    doi:10.1016/s0730-725x(01)00453-2

    authors: Williams DM,Vitellas KM,Sheafor D

    更新日期:2001-11-01 00:00:00

  • Different magnetic resonance imaging features in two types of nontraumatic rabbit osteonecrosis models.

    abstract::A single injection of high-dose steroid (20 mg/kg) has been reported to induce necrotic lesions in the proximal metaphysis and diaphysis of the rabbit femur. In the rabbit osteonecrosis (ON) model induced by two-dose horse serum injections, contrast-enhanced magnetic resonance imaging (MRI) and T2*-weighted dynamic MR...

    journal_title:Magnetic resonance imaging

    pub_type: 杂志文章

    doi:10.1016/j.mri.2008.07.001

    authors: Takao M,Sugano N,Nishii T,Sakai T,Nakamura N,Yoshikawa H

    更新日期:2009-02-01 00:00:00

  • Pure uterine lipoma.

    abstract::Lipomatous tumors of the uterus are unusual, benign neoplasms seen in postmenopausal women. Although many of the mixed-type cases such as lipoleiomyoma and fibrolipoma have been reported, pure uterine lipomas are extremely rare. In the literature, a few cases with pure uterine lipoma have been reported. We first prese...

    journal_title:Magnetic resonance imaging

    pub_type: 杂志文章

    doi:10.1016/j.mri.2007.01.116

    authors: Erdem G,Celik O,Karakas HM,Alkan A,Hascalik S

    更新日期:2007-10-01 00:00:00

  • Correlation of MRI findings to histology of acetaminophen toxicity in the mouse.

    abstract::Acetaminophen (APAP) toxicity is responsible for approximately half of all cases of acute liver failure in the United States. The mouse model of APAP toxicity is widely used to examine mechanisms of APAP toxicity. Noninvasive approaches would allow for serial measurements in a single animal to study the effects of exp...

    journal_title:Magnetic resonance imaging

    pub_type: 杂志文章

    doi:10.1016/j.mri.2011.09.023

    authors: Brown AT,Ou X,James LP,Jambhekar K,Pandey T,McCullough S,Chaudhuri S,Borrelli MJ

    更新日期:2012-02-01 00:00:00

  • The reliability of routine clinical post-processing software in assessing potential diffusion-weighted MRI "biomarkers" in brain metastases.

    abstract:BACKGROUND AND PURPOSE:Diffusion MRI characteristics have been used as biomarkers to guide prognosis in cerebral pathologies including brain metastases. The measurement of ADC is often described poorly in clinical and research studies with little detail given to the practical considerations of where to place ROIs, whic...

    journal_title:Magnetic resonance imaging

    pub_type: 杂志文章

    doi:10.1016/j.mri.2013.12.010

    authors: Zakaria R,Das K,Bhojak M,Radon M,Sluming V,Walker C,Jenkinson MD

    更新日期:2014-04-01 00:00:00

  • Quantifying the dynamic density driven convection in high permeability packed beds.

    abstract::The density driven convection phenomenon is expected to have a significant and positive role in CO2 geological storage capacity and safety. The onset and development of density-driven convective on the core scale is critical to understand the mass transfer mechanism. In this paper, laboratory experiments were conducte...

    journal_title:Magnetic resonance imaging

    pub_type: 杂志文章

    doi:10.1016/j.mri.2017.03.004

    authors: Teng Y,Jiang L,Fan Y,Liu Y,Wang D,Abudula A,Song Y

    更新日期:2017-06-01 00:00:00