Perforated sarcomatoid carcinoma of the jejunum: Case report.

abstract：:The present study aimed to investigate the association between excision repair cross-complementation group 1 (ERCC1) expression and clinical resistance to platinum-based chemotherapy or clinical characteristics, including survival time, in patients with epithelial ovarian cancer (EOC). ERCC1 expression was determined ...

journal_title：Oncology letters

authors： Du P,Wang Y,Chen L,Gan Y,Wu Q

更新日期：2016-08-01 00:00:00

abstract：:Human papillomavirus (HPV) E6 and E7 oncoproteins are essential factors for HPV oncogenesis. These E6 and E7 gene products play a central role in the induction of malignant transformation by interacting with several cellular regulatory proteins such as p16(INK4a), p53 and nuclear factor κB (NF-κB). In the present stud...

journal_title：Oncology letters

authors： Senba M,Mori N,Fujita S,Jutavijittum P,Yousukh A,Toriyama K,Wada A

更新日期：2010-07-01 00:00:00

abstract：:Low-grade endometrial stromal sarcoma (LGESS) is a rare malignancy. The tumor is reportedly responsive to hormonal therapy, most commonly with medroxyprogesterone acetate (MPA), but the effectiveness of aromatase inhibitors for recurrent LGESS remains unclear. The present study reports a case of stage IC LGESS present...

journal_title：Oncology letters

authors： Nakamura K,Nakayama K,Ishikawa M,Ishikawa N,Katagiri H,Katagiri A,Ishibashi T,Sato E,Iida K,Sultana R,Kyo S

更新日期：2016-11-01 00:00:00

abstract：:Gastric cancer is a pathological process of an accumulation of multigene and multistage mutations. A new gene segment, MDSCBC11, has been previously obtained using a gene chip and is negatively associated with gastric cancer. The present study aimed to clone the full cDNA sequence of the MDSCBC11 segment and to detect...

journal_title：Oncology letters

authors： Gan R,Liu X,Zhou Y,Tan Y,Liu H,Li G,Tang Y,Xie H

更新日期：2013-12-01 00:00:00

abstract：:The present study examined the association between squamous cell carcinoma antigen (SCCA) expression and the response of patients with cervical cancer to docetaxel-carboplatin (DC) combination chemotherapy, in order to determine the prognostic potential of SCCA expression. A total of 21 patients were enrolled with sta...

journal_title：Oncology letters

authors： Chen P,Jiao L,Wang DB

更新日期：2017-03-01 00:00:00

abstract：:The current report presents the case of a 43-year-old male suffering from a penile cutaneous horn. A surgical excision of the lesion was performed and histopathology demonstrated hyperkeratosis, dyskeratosis and epithelial hyperplasia. The cutaneous horn progressed to squamous cell carcinoma <1.5 months following surg...

journal_title：Oncology letters

authors： Zhou Y,Tang Y,Tang J,Xia B,Dai Y

更新日期：2014-09-01 00:00:00

abstract：:Neuroblastoma is a neural crest-derived tumor that accounts for 7-10% of all malignancies in children and ~15% of all childhood cancer-associated mortalities. Approximately 50% of patients are characterized as high-risk (HR) and have an overall survival of <40% at 5 years from diagnosis. HR patients with unfavorable p...

journal_title：Oncology letters

authors： Fusco P,Esposito MR,Tonini GP

更新日期：2018-12-01 00:00:00

abstract：:Lung cancer is one of the most common malignancies worldwide; however, its detailed molecular mechanism remains largely unknown. Long non-coding RNAs (lncRNAs) have been identified to serve critical roles in tumorigenesis. The aim of the present study was to investigate the role of a newly identified lncRNA, overexpre...

journal_title：Oncology letters

authors： Zou Y,Zhang B,Mao Y,Zhang H,Hong W

更新日期：2019-09-01 00:00:00

abstract：:Leptomeningeal metastasis (LM) is an uncommon presentation of relapse in breast cancer, which is associated with poor clinical outcomes and poor prognosis. Notably, LM most commonly occurs in breast cancer. The aim of the present review was to investigate the occurrence of LM as the primary presentation of relapse fol...

journal_title：Oncology letters

authors： Sacco K,Muhammad A,Saleem W,Alshaker H,Monzon L,Islam MR,Pchejetski D

更新日期：2016-08-01 00:00:00

abstract：:The present study aimed to investigate the expression levels of microRNA (miR)-23a and miR-23b in the tumor tissues of patients with ovarian cancer. The study also explored the correlation of miR-23a and miR-23b expression levels in the tumor tissues with the clinic-pathological parameters and prognosis of the patient...

journal_title：Oncology letters

authors： Su L,Liu M

更新日期：2018-07-01 00:00:00

abstract：:Leiomyosarcomas account for ~24% of all adult sarcomas, and develop predominantly either in the uterus [uterine leiomyosarcoma (ULMS)] or in deep soft tissue or the retroperitoneum [non-uterine leiomyosarcoma (NULMS)]. Leiomyosarcomas are relatively chemoresistant tumors, and the prognosis of patients with leiomyosarc...

journal_title：Oncology letters

authors： Iura K,Kohashi K,Yasutake N,Ishii T,Maekawa A,Bekki H,Otsuka H,Yamada Y,Yamamoto H,Ohishi Y,Matsumoto Y,Iwamoto Y,Oda Y

更新日期：2018-01-01 00:00:00

abstract：:[-2]pro-prostate-specific antigen (2pPSA), a proform of PSA, is a new marker in patients at risk of prostate cancer. We explored the potential role of 2pPSA in the identification of patients with metastatic progression following radical prostatectomy for prostate cancer. Seventy-six patients with biochemical (PSA) rec...

journal_title：Oncology letters

authors： Sottile A,Ortega C,Berruti A,Mangioni M,Saponaro S,Polo A,Prati V,Muto G,Aglietta M,Montemurro F

更新日期：2012-04-01 00:00:00

abstract：:The purpose of this study was to present the results of fertility-sparing treatment using medroxyprogesterone acetate (MPA) for endometrial carcinoma (EC), and to clarify patient characteristics by investigating patient background factors. A total of 59 patients with EC, who received MPA as fertility-sparing therapy a...

journal_title：Oncology letters

authors： Fujiwara H,Jobo T,Takei Y,Saga Y,Imai M,Arai T,Taneichi A,Machida S,Takahashi Y,Suzuki M

更新日期：2012-05-01 00:00:00

abstract：:Metastasis-associated in colon cancer-1 (MACC1) is a gene that has been newly identified by a genome-wide search for differentially expressed genes in human colon cancer tissues, metastases and normal tissues. MACC1 exerts an important role in colon cancer metastasis through upregulation of the c-Met proto-oncogene. T...

journal_title：Oncology letters

authors： Li H,Zhang H,Zhao S,Shi Y,Yao J,Zhang Y,Guo H,Liu X

更新日期：2015-05-01 00:00:00

abstract：:The aim of the present study was to identify and characterize side population (SP) cells in primary cervical cancer. A primary culture was successfully established, and the SP cells were isolated via fluorescence-activated cell sorting. Subsequently, in vitro analysis of clonogenic capacity by soft agar assay and in v...

journal_title：Oncology letters

authors： Wei ZT,Yu XW,He JX,Liu Y,Zhang SL

更新日期：2017-09-01 00:00:00

abstract：:The multidrug resistance of glioma impedes chemo-radiotherapy and leads to adverse outcomes. In the present study, the doxorubicin (DOX)-resistant glioma SHG44/DOX cell line was established to investigate the effects and mechanisms of Salvia miltiorrhiza ligustrazine (SML), a traditional Chinese medicine, on the rever...

journal_title：Oncology letters

authors： Wang F,Huang N,Yang Q,Liu J,Chen J

更新日期：2017-10-01 00:00:00

abstract：:Evaluation of carcinogenic substances from the environment is a challenge for scientists. Recently, a novel approach based on 10 key characteristics of human carcinogens classified by the International Agency for Research on Cancer (IARC) has emerged. Carcinogenesis depends on different mechanisms and factors, includi...

journal_title：Oncology letters

authors： Calaf GM,Ponce-Cusi R,Aguayo F,Muñoz JP,Bleak TC

更新日期：2020-07-01 00:00:00

abstract：:The long non-coding RNA (lncRNA), RP11-480I12.5 is one of the most dysregulated lncRNAs, which is believed to contribute to the progression of cervical carcinoma (CC); however, the exact function of RP11-480I12.5 in human CC remains unknown. The present study aimed to investigate the function and underlying molecular ...

journal_title：Oncology letters

authors： Zhang L,Li Y,Sona L

更新日期：2020-01-01 00:00:00

abstract：:Propofol is an intravenous anesthetic, which is widely used in clinical anesthesia induction and maintenance and is critical in the sedation of patients. However, the functions and mechanisms of propofol on apoptosis of melanoma cells remain unclear. The present study investigated whether propofol promotes cell apopto...

journal_title：Oncology letters

authors： Shang Z,Feng H,Cui L,Wang W,Fu H

更新日期：2018-01-01 00:00:00

abstract：:The adaptive response of the genome protection mechanism occurs in cells when exposed to genotoxic stress due to the overproduction of free radicals via inflammation and infection. In such circumstances, cells attempt to maintain health via several genome protection mechanisms. However, evidence is increasing that thi...

journal_title：Oncology letters

authors： Loilome W,Kadsanit S,Muisook K,Yongvanit P,Namwat N,Techasen A,Puapairoj A,Khuntikeo N,Phonjit P

更新日期：2017-02-01 00:00:00

abstract：:MicroRNAs (miRs) are a group of short, endogenous, non-protein-coding and single-stranded RNAs that regulate gene expression by binding to the 3'-untranslated region (3'UTR) of mRNAs, which results in their degradation or translational repression. The aim of the present study was to investigate the expression and func...

journal_title：Oncology letters

authors： Kan Q,Su Y,Yang H

更新日期：2017-12-01 00:00:00

abstract：:A standard therapeutic approach for advanced malignant thymoma has yet to be defined given the rarity of this condition. We present a patient with advanced thymoma, evaluated as inoperable at diagnosis due to multiple serosal metastases. The strong constitution and determination of the patient allowed treatment with s...

journal_title：Oncology letters

authors： Bergonzi M,Orlandoni G,Corbella F,Gobbi PG

更新日期：2011-05-01 00:00:00

abstract：:Parathyroid carcinoma (PTCA) is a rare disease, and ectopic PTCA is particularly rare. Parathyroid hormone-related protein (PTHrP) expression in PTCA has not been previously described in the relevant literature to the best of our knowledge. The present study reports a unique case with a mediastinal parathyroid carcino...

journal_title：Oncology letters

authors： Cao C,Dou C,Chen F,Wang Y,Zhang X,Lai H

更新日期：2016-06-01 00:00:00

abstract：:It has been demonstrated that numerous types of metastatic cancer overexpress vacuolar-type H+ (V)-ATPases. It may be possible to inhibit the growth and metastasis of human cancer cells by inhibiting V-ATPases. It was previously reported that diphyllin, a novel V-ATPase inhibitor, can inhibit the migration and invasio...

journal_title：Oncology letters

authors： Pan S,Cai H,Gu L,Cao S

更新日期：2017-11-01 00:00:00

abstract：:The present study aimed to assess the feasibility, safety and efficiency of ultrasound-guided percutaneous microwave ablation (MWA) on liver metastases from colon or rectal cancer. Patients who received MWA therapy for liver metastases from colon or rectal cancer between June 2009 and May 2012 were enrolled in the stu...

journal_title：Oncology letters

authors： Wang J,Liang P,Yu J,Yu MA,Liu F,Cheng Z,Yu X

更新日期：2014-07-01 00:00:00

abstract：:The purpose of this study was to confirm the correlation between serum levels of cystatin C (Cys-C) and those of creatinine (Cre), the most widely used index of renal function in clinical practice, and to evaluate serum levels of Cys-C, with a particular focus on the effects of aging, body mass index (BMI), C-reactive...

journal_title：Oncology letters

authors： Ohara G,Miyazaki K,Kurishima K,Kagohashi K,Ishikawa H,Satoh H,Hizawa N

更新日期：2012-02-01 00:00:00

abstract：:There is a growing body of evidence indicating that several melanoma-associated antigen-A (MAGE-A) subgroups contribute to the malignancy of head and neck cancer. The present study retrospectively analyzed the expression of all known MAGE-A subgroups in the tumor front and center of 38 head and neck cancer patients (U...

journal_title：Oncology letters

authors： Hartmann S,Brisam M,Rauthe S,Driemel O,Brands RC,Rosenwald A,Kübler AC,Müller-Richter UD

更新日期：2016-10-01 00:00:00

abstract：:The frequency of deficient mismatch repair (dMMR) or microsatellite instability-high colorectal cancer (CRC) is estimated to be ~15% of all patients with CRC; however, the patients reported are limited to surgical cases, and the frequency of patients exhibiting stage 0 disease is not considered, despite the currently ...

journal_title：Oncology letters

authors： Sugiyama T,Iwaizumi M,Kaneko M,Tani S,Yamade M,Hamaya Y,Furuta T,Miyajima H,Osawa S,Baba S,Maekawa M,Sugimoto K

更新日期：2020-09-01 00:00:00

abstract：:Non-small cell lung cancer is a subtype of adenocarcinoma, which has previously shown positive responses to gefitinib. The aim of the current study was to determine a clinical profile of gefitinib-induced disease controls for patients with lung adenocarcinoma. Retrospective evaluation of the clinical characteristics o...

journal_title：Oncology letters

authors： Wang Z,Han QB,Gu JL,Yu XM,Sun XJ,Lin QR,Fang J,Wang YZ,Xu YP,Mao WM

更新日期：2015-01-01 00:00:00

abstract：:Acute promyelocytic leukemia (APL) is a rare leukemia characterized by the balanced reciprocal translocation between the promyelocytic leukemia gene on chromosome 15 and the retinoic acid receptor α (RARα) gene on chromosome 17, and accounts for 10-15% of newly diagnosed acute myeloid leukemia each year. The combined ...

journal_title：Oncology letters

authors： Chen C,Huang X,Wang K,Chen K,Gao D,Qian S

更新日期：2018-04-01 00:00:00