Serum levels of cystatin C in elderly lung cancer patients.

abstract：:Glycocholic acid (GCA) is a novel identified biomarker for hepatocellular carcinoma (HCC). However, clinical pathological study of GCA has not been extensive due to the limited availability of anti-GCA monoclonal antibodies (mAbs) and restricted detection methods. In the present study, using human GCA conjugated with ...

journal_title：Oncology letters

authors： Wu M,Zhai S,Gao J,Wei D,Xue J,Zhou Y,Li N,Hu L

更新日期：2019-03-01 00:00:00

abstract：:The aberrant expression of microRNAs (miRs) has a significant impact on the biological characteristics of lymphocytes, and is important in the pathogenesis of diffuse large B-cell lymphoma (DLBCL). It has been demonstrated, using miR profiling and detecting distinct miR signatures, that certain miRs may accurately dis...

journal_title：Oncology letters

authors： Ni H,Tong R,Zou L,Song G,Cho WC

更新日期：2016-02-01 00:00:00

abstract：:The aim of this study was to investigate the effect of dexmedetomidine (Dex) on the respiratory function during anesthesia induction in pediatric patients undergoing retinoblastoma (RB) resection. A total of 87 pediatric patients who underwent RB resection in Yidu Central Hospital of Weifang were recruited into this s...

journal_title：Oncology letters

authors： Rong X,Sun C,Zhang F,Zheng J

更新日期：2019-03-01 00:00:00

abstract：:Downregulation of microRNA-34a (miR-34a) has frequently been observed in esophageal squamous cell carcinoma (ESCC). However, the underlying role and molecular mechanism of miR-34a in ESCC remains largely unknown. In the current study, it was demonstrated that miR-34a was downregulated and forkhead box M1 (FOXM1), a ta...

journal_title：Oncology letters

authors： Zhou H,Yang L,Xu X,Lu M,Guo R,Li D,Huang Q,Liu Y,Deng G,Xu Y

更新日期：2019-01-01 00:00:00

abstract：:Herpesvirus entry mediator (HVEM) displays dual signals in T-cell activation according to the ligands and intracytoplasmic effectors it interacts with. High HVEM expression may play an immunosuppressive role in several malignancies. The present study investigated the clinical impact of HVEM on intrahepatic cholangioca...

journal_title：Oncology letters

authors： Ma B,Meng H,Tian Y,Wang Y,Song T,Zhang T,Wu Q,Cui Y,Li H,Zhang W,Li Q

更新日期：2021-01-01 00:00:00

abstract：:Although previous studies have demonstrated that Glut-1 is the predominant glucose transporter, is significantly overexpressed in various types of tumor and is correlated with poor prognosis, the potential function and clinical value of Glut-1 expression in osteosarcoma remains largely unclear. In particular, the pros...

journal_title：Oncology letters

authors： Fan J,Mei J,Zhang MZ,Yuan F,Li SZ,Yu GR,Chen LH,Tang Q,Xian CJ

更新日期：2017-08-01 00:00:00

abstract：:Pristimerin is an active compound isolated from the traditional Chinese herbs Celastraceae and Hippocrateaceae. It has been reported to exert antitumor effects under experimental and clinical conditions; however, the antitumor effects and underlying mechanisms of pristimerin in oral cancer cells have not yet been iden...

journal_title：Oncology letters

authors： Wu H,Li L,Ai Z,Yin J,Chen L

更新日期：2019-03-01 00:00:00

abstract：:This study aimed to investigate the clinicopathological characteristics, differential diagnosis and prognosis of pulmonary epithelioid hemangioendothelioma (PEH). PEH is a rare low-grade malignant vascular tumor. The cause of PEH remains unclear. Patient prognosis is unpredictable, with life expectancy ranging from 1 ...

journal_title：Oncology letters

authors： Shao J,Zhang J

更新日期：2014-12-01 00:00:00

abstract：:[This corrects the article DOI: 10.3892/ol.2017.6254.]. ...

journal_title：Oncology letters

authors： Sato S,Kato T,Abe K,Hanaoka T,Yano Y,Kurosaki A,Yasuda M,Sekino T,Fujiwara K,Hasegawa K

更新日期：2017-10-01 00:00:00

abstract：:Although there is evidence that galectin-9 is a critical factor in health and disease, the upstream regulatory microRNA (miRNA or miR) of the protein remains poorly defined. miR-455-5p is characterized as a tumor-associated miRNA in cancer research. However, the actual role of miR-455-5p with respect to inhibiting or ...

journal_title：Oncology letters

authors： Yang Q,Hou C,Huang D,Zhuang C,Jiang W,Geng Z,Wang X,Hu L

更新日期：2017-03-01 00:00:00

abstract：:Imaging techniques of upper tract urothelial carcinoma (UTUC) are presently limited. Upconversion particles (UCPs) could be used to target tumors for imaging. The present study aimed to assess the value of a nano-UCP as a diagnostic probe for deep tumor tissue, including UTUC. Polymer-coated water-soluble UCPs were sy...

journal_title：Oncology letters

authors： Liao G,Wang L,Yu W

更新日期：2018-11-01 00:00:00

abstract：:Head and neck squamous cell carcinoma (HNSCC), one of the most common malignant tumors, endangers human health. Recently, the incidence of HNSCC has kept increasing: However, its prognosis has not significantly improved. Understanding the molecular mechanism underlying HNSCC development will therefore provide new stra...

journal_title：Oncology letters

authors： Zou B,Guan X,Zhang W,Wang D,Xu K,Yuan DY,Meng Z,Zhang B

更新日期：2019-12-01 00:00:00

abstract：:Forkhead box M1 (FOXM1) and hedgehog (Hh) signaling pathway are implicated in the formation and development of human tumors, including cervical cancer. Previous studies have indicated that FOXM1 may be a downstream target gene of the Hh signaling pathway, but their association in cervical cancer is largely unknown. In...

journal_title：Oncology letters

authors： Chen H,Wang J,Yang H,Chen D,Li P

更新日期：2016-10-01 00:00:00

abstract：:Determining the resectable region and volume of the liver prior to anatomical resection is important. The synapse Vincent (SV) system is the current method for surgical liver resection that relies on the surgeon's individual experience and skill. Additionally, in cases involving abnormal liver function, the resectable...

journal_title：Oncology letters

authors： Shimoda M,Hariyama M,Oshiro Y,Suzuki S

更新日期：2019-12-01 00:00:00

abstract：:The risk factors for the development of hepatocellular carcinoma (HCC) in patients who have achieved a long-term sustained viral response (SVR) to interferon (IFN) are not fully understood. This study aimed to investigate the characteristics of patients who developed HCC after 10 years of achieving SVR. We retrospecti...

journal_title：Oncology letters

authors： Nojiri K,Sugimoto K,Shiraki K,Kusagawa S,Tanaka J,Beppu T,Yamamoto N,Takei Y,Hashimoto A,Shimizu A,Omori S,Tameda M,Takase K

更新日期：2010-05-01 00:00:00

abstract：:The present study reviewed three patients with acute myeloid leukemia (AML) who had the specific genetic abnormality t(16;21)(p11;q22). To investigate the clinical and laboratory characteristics of AML with t(16;21)(p11;q22) translocation, the similarities and differences of clinical characteristics and laboratory exa...

journal_title：Oncology letters

authors： Zhang Z,Zou J,Li Y,Liu Z,Xu R,Tian W,Zhao Z,Sun H,Han J,Wang J,Zhang B,Ju Y

更新日期：2015-05-01 00:00:00

abstract：:Adenocarcinoma is one of the most serious diseases that threaten human health. Numerous studies have investigated adenocarcinoma and have obtained a considerable amount of data regarding genes and microRNA (miRNA) in adenocarcinoma. However, studies have only focused on one or a small number of genes and miRNAs, and t...

journal_title：Oncology letters

authors： Ning J,Guo X,Wang N,Xue L

更新日期：2015-11-01 00:00:00

abstract：:Scalp angiosarcoma is a rare, extremely aggressive cutaneous malignancy with poor patient prognosis. The present study reviewed the cases of 42 patients who presented scalp angiosarcoma and were treated at the Zhongshan Hospital of Fudan University between January 2002 and December 2013. The clinical characteristics, ...

journal_title：Oncology letters

authors： Zhang Y,Yan Y,Zhu M,Chen C,Lu N,Qi F,Liu J

更新日期：2019-11-01 00:00:00

abstract：:Correlation of APOBEC3G expression with liver function indexes of patients with chronic hepatitis B and its expression in chronic hepatitis B, liver cirrhosis and liver cancer were investigated to evaluated the significance of APOBEC3G. Fifty-eight patients with chronic hepatitis B were selected, including 20 cases of...

journal_title：Oncology letters

authors： Ni L,Li C,Li Y

更新日期：2020-03-01 00:00:00

abstract：:Patients with non-platinum-sensitive recurrent ovarian cancer have a poor prognosis. Non-pegylated liposomal doxorubicin (Myocet®) is a promising drug that may be able to improve treatment for such patients. In the current study, patients with recurrent ovarian cancer relapsing within 12 months after primary treatment...

journal_title：Oncology letters

authors： Brucker J,Mayer C,Gebauer G,Mallmann P,Belau AK,Schneeweiss A,Sohn C,Eichbaum M

更新日期：2016-08-01 00:00:00

abstract：:Lung cancer is one of the leading causes of cancer-associated mortality. C-reactive protein (CRP), albumin (ALB), globulin (GLB), lactate dehydrogenase (LDH), neutrophil-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) have been identified as general parameters for systemic inflammatory response (SIR). Fu...

journal_title：Oncology letters

authors： Zhu J,Lian L,Qin H,Wang WJ,Ren R,Xu MD,Chen K,Duan W,Gong FR,Tao M,Zhi Q,Wu MY,Li W

更新日期：2019-02-01 00:00:00

abstract：:Zinc finger E-box binding homeobox 1 (ZEB1) has been shown to promote invasion and metastasis in several types of human cancer and to have a prognostic role in certain cancers. However, the clinical significance of ZEB1 in colorectal cancer (CRC) has not been sufficiently investigated. This study aimed to address this...

journal_title：Oncology letters

authors： Zhang GJ,Zhou T,Tian HP,Liu ZL,Xia SS

更新日期：2013-02-01 00:00:00

abstract：:MicroRNAs (miRNAs/miRs) are small, noncoding RNA molecules that are closely associated with the occurrence and development of tumors. miR-20b is overexpressed in hepatocellular carcinoma cell lines and tissues. However, it is not clear whether miR-20b can promote the proliferation of hepatocellular carcinoma cells. In...

journal_title：Oncology letters

authors： He J,Mu M,Luo Y,Wang H,Ma H,Guo S,Fang Q,Qian Z,Lu H,Song C

更新日期：2019-03-01 00:00:00

abstract：:The present study aimed to investigate potential recurrence-risk biomarkers based on significant pathways for Luminal A breast cancer through gene expression profile analysis. Initially, the gene expression profiles of Luminal A breast cancer patients were downloaded from The Cancer Genome Atlas database. The differen...

journal_title：Oncology letters

authors： Gao H,Yang M,Zhang X

更新日期：2018-04-01 00:00:00

abstract：:The causes of lung cancer in never-smokers remain unclear. The potential contribution of human papillomavirus (HPV) to the carcinogenesis of non-small cell lung cancer (NSCLC) has been reported. In 2008, a prospective registry of never-smokers with NSCLC was established at the Kinki-Chuo Chest Medical Center, Sakai, O...

journal_title：Oncology letters

authors： Isa SI,Kurahara Y,Yamamoto S,Tamiya A,Omachi N,Asami K,Okishio K,Utsumi T,Ito N,Yoon HE,Matsumura A,Atagi S,Kawaguchi T

更新日期：2015-02-01 00:00:00

abstract：:Gastric cancer is a major cause of cancer-associated mortality worldwide. The aberrant expression of microRNA (miRNA) is involved in tumorigenesis. Ras proteins transfer information from the extracellular environment to internal cellular compartments and are essential in numerous signal transduction pathways. To inves...

journal_title：Oncology letters

authors： Bo X,Chen Y,Sheng W,Gong Y,Wang H,Gao W,Zhang B

更新日期：2018-03-01 00:00:00

abstract：:The present study aimed to identify the level of programmed death-1 (PD-1) expression in infiltrating cluster of differentiation (CD)4+ and CD8+ T cells isolated from lung cancer tissues, and investigated whether the level of PD-1 expression may be directly regulated by lung cancer cells via prostaglandin E2 (PGE2)-as...

journal_title：Oncology letters

authors： Wang J,Zhang L,Kang D,Yang D,Tang Y

更新日期：2018-01-01 00:00:00

abstract：:FP3 (KH902/KH903) is a novel vascular endothelial growth factor (VEGF) blocker with antiangiogenic properties. Previous studies revealed that FP3, a humanized fusion protein that combines ligand binding elements from the extracellular domains of VEGF receptors 1 and 2 and the Fc portion of IgG1, has an inhibitory effe...

journal_title：Oncology letters

authors： Jin K,Lan H,Cao F,Xu Z,Han N,Li G,He K,Teng L

更新日期：2012-05-01 00:00:00

abstract：:Although cisplatin (DDP) has been reported to be a promising antitumor therapy for non-small cell lung cancer (NSCLC), the effectiveness of the treatment remains limited due to an inherent tumor resistance to DDP. Genistein (GEN) is an abundant, naturally occurring isoflavonoid found in soy products that has been demo...

journal_title：Oncology letters

authors： Liu D,Yan L,Wang L,Tai W,Wang W,Yang C

更新日期：2014-12-01 00:00:00

abstract：:Cervical cancer is the third most common malignancy worldwide, accounting for 250,000 mortalities annually. Notch1, an important regulator of cell-fate decisions and differentiation, has been found to be overexpressed in certain types of cancer. However, the role of Notch1 in cervical carcinogenesis remains unclear. I...

journal_title：Oncology letters

authors： Sun Y,Zhang R,Zhou S,Ji Y

更新日期：2015-06-01 00:00:00