Abstract：
:Most animals develop coelomic cavities lined by an epithelial cell layer called the mesothelium. Embryonic mesothelial cells have the ability to transform into mesenchymal cells which populate many developing organs contributing to their connective and vascular tissues, and also to organ-specific cell types. Furthermore, embryonic mesothelium and mesothelial-derived cells produce essential signals for visceral morphogenesis. We review the most relevant literature about the mechanisms regulating the embryonic mesothelial-mesenchymal transition, the developmental fate of the mesothelial-derived cells and other functions of the embryonic mesothelium, such as its contribution to the establishment of left-right visceral asymmetries or its role in limb morphogenesis.
journal_name
Semin Cell Dev Bioljournal_title
Seminars in cell & developmental biologyauthors
Carmona R,Ariza L,Cano E,Jiménez-Navarro M,Muñoz-Chápuli Rdoi
10.1016/j.semcdb.2018.09.006subject
Has Abstractpub_date
2019-08-01 00:00:00pages
37-44eissn
1084-9521issn
1096-3634pii
S1084-9521(17)30538-4journal_volume
92pub_type
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journal_title：Seminars in cell & developmental biology
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journal_title：Seminars in cell & developmental biology
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