Centrioles in flies: the exception to the rule?

Abstract:

:Centrioles and basal bodies are MT based structures that present a highly conserved ninefold symmetry. Centrioles can be found at the core of the centrosome where they participate in PCM recruitment and organization, contributing to cytoplasmic MT nucleation. Basal bodies are normally located closely to the plasma membrane where they are responsible for axoneme assembly to form structures such as cilia or flagella. While it is well accepted that these organelles have important roles in cell and tissue organization, their contribution to certain phases of animal development is still not entirely established. Here we review the role of centrosomes and cilia in Drosophila melanogaster and briefly discuss the implications of these findings to other model organisms.

journal_name

Semin Cell Dev Biol

authors

Gogendeau D,Basto R

doi

10.1016/j.semcdb.2009.07.001

subject

Has Abstract

pub_date

2010-04-01 00:00:00

pages

163-73

issue

2

eissn

1084-9521

issn

1096-3634

pii

S1084-9521(09)00148-7

journal_volume

21

pub_type

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