Abstract:
INTRODUCTION:Inflammation is an important contributor to the development of chronic diseases. We examined whether a healthy Nordic diet, also called the Baltic Sea diet, associates with lower concentrations of inflammatory markers. METHODS:We used two independent cross-sectional studies: the DILGOM study including Finnish participants aged 25-74 years (n = 4579), and the Helsinki Birth Cohort Study including individuals born at Helsinki University Central Hospital between 1934 and 1944 and who participated in a clinical examination in 2001-2004 (n = 1911). Both studies measured anthropometrics, drew blood, and assessed concentrations of leptin, high-molecular-weight adiponectin, tumor necrosis factor α, interleukin 6, and high-sensitivity C-reactive protein (hs-CRP). A food frequency questionnaire was used to measure dietary intake over the past year and calculate the Baltic Sea Diet Score (BSDS). RESULTS:In both studies, linear regression adjusting for age, sex, energy intake, lifestyle factors, obesity, statin medication, and upstream inflammatory markers revealed an inverse association between the BSDS and hs-CRP concentrations (P < 0.01). Especially, high intake of Nordic fruits and cereals, low intake of red and processed meat, and moderate intake of alcohol contributed to the emerged association (P < 0.05). The BSDS did not associate with other inflammatory markers. CONCLUSION:The Baltic Sea diet is associated with lower hs-CRP concentrations.
journal_name
Ann Medjournal_title
Annals of medicineauthors
Kanerva N,Loo BM,Eriksson JG,Leiviskä J,Kaartinen NE,Jula A,Männistö Sdoi
10.3109/07853890.2013.870020subject
Has Abstractpub_date
2014-03-01 00:00:00pages
90-6issue
2eissn
0785-3890issn
1365-2060journal_volume
46pub_type
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