Sequence analysis of the genes encoding for H+/K+-ATPase in autoimmune gastritis.

abstract：:The WHO Multinational Monitoring of Trends and Determinants in Cardiovascular Disease (MONICA) Project was initiated in the early 1980s with the main objective of assessing the extent to which trends in coronary heart disease and cerebrovascular disease are related to changes in known risk factors, daily living habits...

journal_title：Annals of medicine

authors： Gutzwiller F

更新日期：1994-02-01 00:00:00

abstract：:One of the major discoveries in modern genetics is the phenomenon of genomic, or parental, imprinting. The parent-of-origin effects seen after transmission of an imprinted gene from parents to their children do not follow the genetic rules postulated by Gregor Mendel. This has obvious consequences for genetic counsell...

journal_title：Annals of medicine

authors： Mannens M,Alders M

更新日期：1999-02-01 00:00:00

abstract：:The prevalence of immunoglobulin E (IgE)-mediated allergic diseases has been increasing for the last four decades. In this review determinants for an increased IgE synthesis are discussed on both an epidemiological and on an immunological level with special emphasis on the differentiation of the B cell to an IgE-produ...

journal_title：Annals of medicine

authors： Poulsen LK,Hummelshoj L

更新日期：2007-01-01 00:00:00

abstract：:Hypertrophic cardiomyopathy (HCM) is an autosomal dominant disease caused by mutations in sarcomeric proteins. It is characterized by left ventricular hypertrophy in the absence of an increased external load, and myofibrillar disarray. While hypertrophy is a common cardiac response to injury, disarray is the pathologi...

journal_title：Annals of medicine

authors： Marian AJ,Roberts R

更新日期：1998-08-01 00:00:00

abstract：:There is increasing evidence that fasting hypertriglyceridaemia identifies individuals who are at increased risk for coronary artery disease. It is probable that this reflects the effects of the smaller triglyceride-bearing lipoproteins. It may also reflect increased levels of postprandial lipoproteins. There is consi...

journal_title：Annals of medicine

authors： Steiner G

更新日期：1993-10-01 00:00:00

abstract：:The mucosal surfaces are the first portals of entry for most infectious agents, among which respiratory and intestinal viruses are of greatest epidemiological importance. To combat these infections, the immune system uses unspecific and specific mechanisms. Unspecific responses include the production of virus-induced ...

journal_title：Annals of medicine

authors： Freihorst J,Ogra PL

更新日期：2001-04-01 00:00:00

abstract：BACKGROUND AIMS:A mild increase in liver enzyme levels is sometimes observed in patients with diabetic ketosis or ketoacidosis. The aim of the present study was to assess the cause and prevalence of the elevation of liver transaminase levels in fulminant and acute-onset type 1 diabetic patients experiencing diabetic ke...

journal_title：Annals of medicine

authors： Takaike H,Uchigata Y,Iwamoto Y,Imagawa A,Iwahashi H,Kanatsuka A,Kawasaki E,Kobayashi T,Shimada A,Shimizu I,Maruyama T,Hanafusa T,Makino H

更新日期：2008-01-01 00:00:00

abstract：:Statins are the first-line choice in Lipid-lowering therapy to reduce cardiovascular risk. In a continuous attempt to optimise treatment success, there is a need for additional research on genes and related molecular pathways that can determine the efficacy and toxicity of lipid-lowering drugs. Several variations with...

journal_title：Annals of medicine

authors： Ahangari N,Doosti M,Ghayour Mobarhan M,Sahebkar A,Ferns GA,Pasdar A

更新日期：2020-12-01 00:00:00

abstract：:Scleroderma or systemic sclerosis (SSc) is a complex disease in which the vasculopathy and the activation of the immune system with production of inflammatory mediators lead to dysregulated fibroblast activation. The resulting excessive deposition of collagens and other extracellular matrix proteins ends in fibrosis a...

journal_title：Annals of medicine

authors： Chizzolini C

更新日期：2007-01-01 00:00:00

abstract：:Although obesity and alcohol intake as well as dietary sodium, potassium and magnesium are the major non-genetic determinants of blood pressure levels, interest has recently been stimulated in the function of fatty acids and antioxidants in the aetiology of hypertension. In the Kuopio Ischaemic Heart Disease Risk Fact...

journal_title：Annals of medicine

authors： Salonen JT

更新日期：1991-08-01 00:00:00

abstract：:Cardiac rhythm during sleep was analysed in 168 healthy men aged 19 to 30 (mean 21.8) years using continuous nocturnal ECG recordings. Thirty five of the subjects were endurance athletes; 99 were recorded at home and 69 at a garrison during military service. The number of short term (less than one min) accelerations o...

journal_title：Annals of medicine

authors： Viitasalo M,Halonen L,Partinen M,Iivanainen M,Kala R,Eisalo A

更新日期：1991-04-01 00:00:00

abstract：:Several lines of evidence suggest that abnormal brain serotonin metabolism may occur in early onset, type 2 alcoholism in men. Low cerebrospinal fluid 5-hydroxy-indoleacetic acid concentration has been found to be associated with a history of paternal alcoholism, and abnormal oral glucose tolerance tests (tendency to ...

journal_title：Annals of medicine

authors： Virkkunen M,Linnoila M

更新日期：1990-01-01 00:00:00

abstract：:The Cardiovascular Risk in Young Finns Study is a collaborative effort of all university departments of paediatrics and several other institutions in Finland to study the risk factors of coronary heart disease (CHD) and their determinants in children and adolescents in different parts of the country. The main cross-se...

journal_title：Annals of medicine

authors： Akerblom HK,Viikari J,Raitakari OT,Uhari M

更新日期：1999-04-01 00:00:00

abstract：:About 40 years ago Friedenstein described stromal cells in the bone marrow that were spindle shaped and proliferate to form colonies. These cells attach to plastic and are able to differentiate under defined in vitro conditions into multiple cell types present in many different tissues, e.g. osteoblasts, chondroblasts...

journal_title：Annals of medicine

authors： Väänänen HK

更新日期：2005-01-01 00:00:00

abstract：AIM:To evaluate dyslipidemia as predictor of myocardial infarction (MI) in subjects with or without chronic kidney disease (CKD). METHODS:In 142,394 middle-aged Swedes referred for laboratory evaluation, glomerular filtration rates (GFR) were estimated using the Modification of Diet in Renal Disease study equation. CK...

journal_title：Annals of medicine

authors： Holzmann MJ,Jungner I,Walldius G,Ivert T,Nordqvist T,Ostergren J,Hammar N

更新日期：2012-05-01 00:00:00

abstract：:More than 50 different pharmacological and mechanical interventions have been tested to date for prevention of vascular restenosis without success. Intracoronary radiotherapy is the first one showing promise of significantly attenuating neointimal proliferation, causing positive vascular remodelling and thus inhibitin...

journal_title：Annals of medicine

authors： Kaluza GL,Ali NM,Raizner AE

更新日期：2000-12-01 00:00:00

abstract：:Certain bacterial infections have been demonstrated to be causative of reactive arthritis. The most common bacterial trigger of reactive arthritis is Chlamydia trachomatis. Chlamydia pneumoniae is another known cause, albeit far less frequently. Although Chlamydia-induced reactive arthritis will often spontaneously re...

journal_title：Annals of medicine

authors： Carter JD,Inman RD,Whittum-Hudson J,Hudson AP

更新日期：2012-12-01 00:00:00

abstract：:Aggregates of dysfunctional proteins and peptides in or between brain neurons are key neuropathological features of dementia and are believed to directly cause or substantially contribute to the development of these diseases. Fundamental parts of the mechanisms underlying the dysregulation of proteins in Alzheimer's d...

journal_title：Annals of medicine

authors： Ingelsson M,Hyman BT

更新日期：2002-01-01 00:00:00

abstract：:Although food habits arc not stable and unchanging during a person's lifetime, a base for healthy food habits can be created in early childhood. Children's food habits can be assumed to be influenced by their parents' food habits and choices. The aim of this article is to review factors influencing food choice in chil...

journal_title：Annals of medicine

authors： Hursti UK

更新日期：1999-01-01 00:00:00

abstract：:Objective: Investigation of the clinical potential of extensive phenotype data and machine learning (ML) in the prediction of mortality in acute coronary syndrome (ACS). Methods: The value of ML and extensive clinical data was analyzed in a retrospective registry study of 9066 consecutive ACS patients (January 2007 to...

journal_title：Annals of medicine

authors： Hernesniemi JA,Mahdiani S,Tynkkynen JA,Lyytikäinen LP,Mishra PP,Lehtimäki T,Eskola M,Nikus K,Antila K,Oksala N

更新日期：2019-03-01 00:00:00

abstract：:Inflammatory diseases are on the rise in westernized countries, but also in urbanized areas of developing countries. A number of studies have now demonstrated a negative association between helminth infections and inflammatory diseases, such as allergy, suggesting a potential role for helminth-induced immune responses...

journal_title：Annals of medicine

authors： Smits HH,Yazdanbakhsh M

更新日期：2007-01-01 00:00:00

abstract：OBJECTIVES:To appraise effective predictors for COVID-19 mortality in a retrospective cohort study. METHODS:A total of 1270 COVID-19 patients, including 984 admitted in Sino French New City Branch (training and internal validation sets randomly split at 7:3 ratio) and 286 admitted in Optical Valley Branch (external va...

journal_title：Annals of medicine

authors： Guan X,Zhang B,Fu M,Li M,Yuan X,Zhu Y,Peng J,Guo H,Lu Y

更新日期：2021-12-01 00:00:00

abstract：OBJECTIVE:To assess the relationship between the FRAX index and the Barthel index/MiniMental State Examination in older people. PATIENTS AND METHODS:Observational descriptive study. Demographic data, comorbidity, dependency and cognitive state, and risk of osteoporotic fracture were collected. RESULTS:A total of 375 ...

journal_title：Annals of medicine

authors： González Silva Y,Abad Manteca L,de la Red Gallego H,Álvarez Muñoz M,Rodríguez Carbajo M,Murcia Casado T,Ausín Pérez L,Abadía Otero J,Pérez-Castrillón JL

更新日期：2018-09-01 00:00:00

abstract：INTRODUCTION:The association between sleep disturbances and cardiometabolic diseases has been understudied in blacks with metabolic syndrome. METHODS:This study is a cross-sectional analysis of the Metabolic Syndrome Outcome Study (MetSO) trial. We assessed insomnia symptoms, sleep duration, and risk for sleep apnea. ...

journal_title：Annals of medicine

authors： Ramos AR,Wallace DM,Pandi-Perumal SR,Williams NJ,Castor C,Sevick MA,Mcfarlane SI,Jean-Louis G

更新日期：2015-05-01 00:00:00

abstract：:Mitochondria provide cells with most of the energy in the form of adenosine triphosphate (ATP). Mitochondria are complex organelles encoded both by nuclear and mtDNA. Only a few mitochondrial components are encoded by mtDNA, most of the mt-proteins are nuclear DNA encoded. Remarkably, the majority of the known mutatio...

journal_title：Annals of medicine

authors： Maassen JA,Janssen GM,'t Hart LM

更新日期：2005-01-01 00:00:00

abstract：:Troglitazone is a novel once-daily oral antidiabetic agent for the treatment of type 2 diabetes patients. Here, we report the overall dose response characteristics of troglitazone, with respect to effects on metabolic control, using a pharmacodynamic model. Data from week 12 from two previously reported double-blind, ...

journal_title：Annals of medicine

authors： Young MA,Eckland DJ,Eastmond R,Lettis S

更新日期：1998-04-01 00:00:00

abstract：:Atrial fibrillation is a common cardiac arrhythmia with rapid and irregular atrial activity. Instead of uniformly contracting as one chamber, the atrial compartment fibrillates. Several studies have demonstrated that this arrhythmia contributes substantially to cardiac morbidity and mortality. The purpose of this revi...

journal_title：Annals of medicine

authors： Miyazaki S,Shah AJ,Scherr D,Haïssaguerre M

更新日期：2011-01-01 00:00:00

abstract：:In Europe around 1970 there were only a few small and often poorly known epidemiological studies on risk factors and the incidence of coronary heart disease. In order to enhance the utilization of the information contained in them, the Medical Clinic in Heidelberg offered uniform data analysis to qualifying contributi...

journal_title：Annals of medicine

authors： Lamm G

更新日期：1989-06-01 00:00:00

abstract：:In the aetiological diagnosis of pulmonary infections in patients affected by haematological malignancies we evaluated the utility of bronchoalveolar lavage (BAL). One hundred and twenty-seven BAL were performed in 119 patients. In our series, we identified the agent of pneumonia in 53.5% of episodes with the best res...

journal_title：Annals of medicine

authors： Pagano L,Pagliari G,Basso A,Marra R,Sica S,Frigieri L,Morace G,Ardito F,Leone G

更新日期：1997-12-01 00:00:00

abstract：BACKGROUND AND AIMS:The expression of disintegrin and metalloprotease ADAM-9, ADAM-15, and ADAM-17 has been associated with cell-cell, cell-platelet, and cell-matrix interactions and inflammation. They are possibly implicated in the pathophysiology of atherosclerosis. METHODS AND RESULTS:Whole-genome expression array ...

journal_title：Annals of medicine

authors： Oksala N,Levula M,Airla N,Pelto-Huikko M,Ortiz RM,Järvinen O,Salenius JP,Ozsait B,Komurcu-Bayrak E,Erginel-Unaltuna N,Huovila AP,Kytömäki L,Soini JT,Kähönen M,Karhunen PJ,Laaksonen R,Lehtimäki T

更新日期：2009-01-01 00:00:00