Abstract:
PURPOSE:To determine whether apparent diffusion coefficient (ADC) values vary according to tumor-stroma ratio, dominant stroma type, or presence of central fibrosis in estrogen receptor-positive breast cancer. MATERIALS AND METHODS:Institutional review board approval was obtained, and patient consent was waived. Sixty-one patients with estrogen receptor-positive invasive ductal carcinoma-not otherwise specified who underwent breast magnetic resonance (MR) imaging with diffusion-weighted (DW) imaging were included in this study. The ADC values of the lesions were measured. Two pathologists evaluated the tumor-stroma ratio, dominant stroma type (collagen, fibroblast, lymphocyte), and central fibrosis. Detectability on DW images was compared between the two groups according to the tumor-stroma ratio (stroma rich or stroma poor). Mean ADC values were retrospectively compared with the tumor-stroma ratio, dominant stroma type, and presence of a central fibrosis. Multiple linear regression analysis was performed to determine variables independently associated with ADC. RESULTS:On DW images, detectability was not significantly different between stroma-rich and stroma-poor groups (P = .244). ADC values were significantly lower in the stroma-poor group (P < .001). The mean ADC values in the collagen-dominant type were lower than in fibroblast-dominant or lymphocyte-dominant types (P = .021). In multiple linear regression analysis, tumor-stroma ratio (P = .007), tumor size (P = .007), and dominant stroma type (collagen dominant, P = .029) were independently correlated with ADC. CONCLUSION:In estrogen receptor-positive breast cancers, ADC values showed significant differences according to the tumor-stroma ratio and dominant stroma type.
journal_name
Radiologyjournal_title
Radiologyauthors
Ko ES,Han BK,Kim RB,Cho EY,Ahn S,Nam SJ,Ko EY,Shin JH,Hahn SYdoi
10.1148/radiol.13131073subject
Has Abstractpub_date
2014-04-01 00:00:00pages
30-7issue
1eissn
0033-8419issn
1527-1315journal_volume
271pub_type
杂志文章相关文献
RADIOLOGY文献大全abstract::Twenty-three patients with malignant hepatic tumors underwent magnetic resonance (MR) imaging before and after intravenous administration of gadolinium-diethylene-triaminepentaacetic acid (DTPA). Two different doses were used, 0.1 mmol/kg and 0.2 mmol/kg. The larger dose proved to be more effective than the smaller do...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiology.164.2.3037590
更新日期:1987-08-01 00:00:00
abstract:PURPOSE:To test the hypothesis that computed tomographic (CT) scanning during early rather than middle diastole can significantly reduce the interscan variability of coronary artery calcium (CAC) scores. MATERIALS AND METHODS:Five hundred thirty-eight patients were initially enrolled; 282 of them were found to have CA...
journal_title:Radiology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1148/radiol.2203001129
更新日期:2001-09-01 00:00:00
abstract::A consensus does not exist as to the optimal contrast agent for hysterosalpingography. This study was undertaken to evaluate the early and delayed inflammatory responses of the peritoneal surfaces to various types of iodinated contrast media. Guinea pigs received intraperitoneal injections of lactated Ringer solution,...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiology.172.1.2544920
更新日期:1989-07-01 00:00:00
abstract:PURPOSE:To investigate the cost-effectiveness of computed tomography (CT) relative to radiography for cervical spine screening in trauma patients. MATERIALS AND METHODS:A decision analysis model was constructed to compare the incremental cost-effectiveness of radiography and CT as primary cervical spine screening moda...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiology.212.1.r99jl08117
更新日期:1999-07-01 00:00:00
abstract:PURPOSE:To retrospectively determine whether there is a relationship between the intranodular blood supply evaluated at computed tomography (CT) during arterial portography (CTAP) and CT during hepatic arteriography (CTHA) and the magnetic resonance (MR) imaging signal intensity of nodules associated with cirrhosis. M...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiol.2372041389
更新日期:2005-11-01 00:00:00
abstract:PURPOSE:To evaluate the potential of quantitative susceptibility (QS) and R2* mapping as surrogate biomarkers of clinically relevant, age-adjusted demyelination and iron deposition in multiple sclerosis (MS). MATERIALS AND METHODS:All study participants gave written informed consent, and the study was approved by the ...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiol.14132475
更新日期:2014-09-01 00:00:00
abstract::Purpose To report the impact of changing from screen-film mammography to digital mammography (DM) in a large organized national screening program. Materials and Methods A retrospective analysis of prospectively collected annual screening data from 2009-2010 to 2015-2016 for the 80 facilities of the English National He...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiol.2018181426
更新日期:2019-03-01 00:00:00
abstract:PURPOSE:To describe a program for controlling intravenous use of low-osmolar contrast agents (LOCAs). MATERIALS AND METHODS:The department of radiology at the authors' institution adopted a policy of selective use of intravenously administered LOCAs. Clinical indications for LOCA use were specified after consultation ...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiology.189.3.8234700
更新日期:1993-12-01 00:00:00
abstract:PURPOSE:To evaluate the effect of the increase in total cross-sectional area of arteries as they branch beyond the main trunks on the resistive index (RI) and early systolic acceleration (ESA). MATERIALS AND METHODS:An essentially noncompliant in vitro model that used a pulsatile pump, blood-mimicking fluid, and a bra...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiology.212.3.r99se13732
更新日期:1999-09-01 00:00:00
abstract::The extraperitoneal space around the urinary bladder is lamellate, just like the retroperitoneal space around the kidneys. The bladder, urachus, and obliterated umbilical arteries lie within the perivesical space, surrounded by umbilicovesical fascia, analogous to the perinephric space within the renal fascia. A much ...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiology.159.2.2938210
更新日期:1986-05-01 00:00:00
abstract:PURPOSE:To prospectively evaluate the learning curves and reading times of inexperienced readers who used the virtual dissection reading method for retrospective computed tomographic (CT) colonography data sets, with and without concurrent computer-aided detection (CAD). MATERIALS AND METHODS:An Institutional Review B...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiol.2482070895
更新日期:2008-09-01 00:00:00
abstract:PURPOSE:To demonstrate the variety and recurrence patterns of severe arterial and venous thromboembolic events that occur in patients with the antiphospholipid syndrome. MATERIALS AND METHODS:Radiology records were reviewed in 800 of 1,633 patients with positive test results of antiphospholipid syndrome. Patients with...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiology.202.2.9015050
更新日期:1997-02-01 00:00:00
abstract:PURPOSE:To compare the postdural puncture headache (PDPH) rates after myelography with use of 22-gauge Whitacre (blunt tip) versus standard 22-gauge Quincke (bevel-tip) spinal needles. MATERIALS AND METHODS:At myelography, 340 patients were randomly assigned to one of two groups in which either the Whitacre (167 patie...
journal_title:Radiology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1148/radiology.200.3.8756930
更新日期:1996-09-01 00:00:00
abstract:PURPOSE:To measure scanner and patient variation in computed tomographic (CT) numbers for electron-beam CT and to determine the ability of calibration phantoms to reduce variability in calcium quantitation. MATERIALS AND METHODS:Two calibration phantoms were imaged to ensure longitudinal homogeneity and to determine t...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiology.196.1.7784560
更新日期:1995-07-01 00:00:00
abstract::Sports-related muscle pain is frequent in both trained and untrained persons; however, its severity and significance may be difficult to assess clinically. The authors used magnetic resonance (MR) imaging to evaluate acute strains and delayed-onset muscle soreness in sedentary subjects and postmarathon myalgia in trai...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiology.172.3.2772190
更新日期:1989-09-01 00:00:00
abstract:PURPOSE:To evaluate prospectively bolus tracking to time hepatic arterial phase (HAP) imaging of hypervascular hepatocellular carcinomas (HCCs) with a 40-detector computed tomographic (CT) scanner. MATERIALS AND METHODS:This study received institutional review board approval; informed consent was obtained. The study i...
journal_title:Radiology
pub_type: 杂志文章,随机对照试验
doi:10.1148/radiol.2431060069
更新日期:2007-04-01 00:00:00
abstract:PURPOSE:To determine characteristic features of peripheral cholangiocarcinoma on two-phase spiral computed tomographic (CT) scans. MATERIALS AND METHODS:Thirty-four patients with peripheral cholangiocarcinoma underwent two-phase spiral CT. Hepatic arterial phase and portal venous phase images were obtained 30 and 65 s...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiology.204.2.9240550
更新日期:1997-08-01 00:00:00
abstract:PURPOSE:To prospectively assess the effect of including or excluding endocardial trabeculae in left ventricular (LV) measurements and the reproducibility of these measurements at cine cardiovascular magnetic resonance (MR) imaging with true fast imaging with steady-state precession (FISP). MATERIALS AND METHODS:The st...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiol.2353040601
更新日期:2005-07-01 00:00:00
abstract:PURPOSE:To prospectively evaluate multiobserver diagnostic performance and reader agreement for colorectal polyp detection in a well-characterized cohort of patients with increased number of polyps, compared with an average-risk patient, with colonoscopy as the reference standard. MATERIALS AND METHODS:A cohort of 70 ...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiol.2252011625
更新日期:2002-11-01 00:00:00
abstract:PURPOSE:To evaluate the effect of preprocedural prediction of the best tube angle obliquity for visualization of the uterine artery origin by using three-dimensional (3D)-reconstructed contrast material-enhanced magnetic resonance (MR) angiography on the radiation dose, fluoroscopy time, and contrast medium volume duri...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiol.2513081751
更新日期:2009-06-01 00:00:00
abstract::Magnetic resonance (MR) imaging-related artifacts associated with five different aneurysm clips made of five different metals (commercially pure titanium, titanium alloy, Phynox, Elgiloy, and cobalt alloy) were evaluated. Aneurysm clips made of commercially pure titanium and titanium alloy produced the smallest artifa...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiology.209.2.9807590
更新日期:1998-11-01 00:00:00
abstract::Balloon dilation is a well-described, nonoperative, alternative treatment for postoperative strictures of the colon and rectum. This procedure may not be technically feasible when an occluded lumen prevents passage of a guide wire across the obstruction. The authors describe the use of transrectal ultrasound guidance ...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiology.189.2.8210400
更新日期:1993-11-01 00:00:00
abstract:PURPOSE:To assess pregnancy outcome in patients with amniotic sheets and to determine whether outcome is affected by placental implantation on the amniotic sheet. MATERIALS AND METHODS:Sonograms obtained during the 2nd and 3rd trimesters were reviewed in 157 patients with amniotic sheets to confirm the presence of an ...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiology.206.3.9494500
更新日期:1998-03-01 00:00:00
abstract::An anomalous branch of the cavernous carotid artery, not reported previously, is described. Its appearance and distribution were unlike those of any known cavernous branch, originating at the level where the trigeminal artery is usually found but having no communication with the basilar artery. Its distribution approx...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/116.1.93
更新日期:1975-07-01 00:00:00
abstract:PURPOSE:To study white matter (WM) changes in patients with Unverricht-Lundborg progressive myoclonus epilepsy (EPM1) caused by mutations in the cystatin B gene and in the cystatin B-deficient (Cstb-/-) mouse model and to validate imaging findings with histopathologic analysis of mice. MATERIALS AND METHODS:Informed c...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiol.13122458
更新日期:2013-10-01 00:00:00
abstract::In order to test a hypothesis that the routine use of one midsagittal and four preselected coronal reconstruction images would disclose lesions unsuspected on standard cranial computed tomography (CT) scans, 204 patient examinations were subjected to such multiplanar reconstruction manipulation; the original CT diagno...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiology.140.1.7244210
更新日期:1981-07-01 00:00:00
abstract::A 49-year-old premenopausal woman presented with acute onset of lower abdominal pain. Physical examination revealed her abdomen was distended and nontender. Her white blood cell count and serum markers for ovarian cancer were normal (alpha-fetoprotein level, 1.6 microg/L; Ca-125 level, 15 U/mL; beta-human chorionic go...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiol.2441040790
更新日期:2007-07-01 00:00:00
abstract::Rod-shaped reflectors such as those used in the AIUM test object resonate at medical ultrasound frequencies, producing artifacts posterior to the reflector. Rods of various diameters and materials were examined to determine their resonant properties, and the effect of the Plexiglas scanning surface of the enclosure on...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiology.139.1.7208920
更新日期:1981-04-01 00:00:00
abstract:PURPOSE:To evaluate diagnostic performance of three nonenhanced methods: variable-refocusing-flip angle (FA) fast spin-echo (SE)-based magnetic resonance (MR) angiography (variable FA MR) and constant-refocusing-FA fast SE-based MR angiography (constant-FA MR) and flow-sensitive dephasing (FSD)-prepared steady-state fr...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiol.12120859
更新日期:2013-04-01 00:00:00
abstract::It has recently been suggested that the resistive index (RI) in native kidneys of healthy children is age dependent; however, this relationship has not been completely defined or explained. In 110 kidneys in 71 healthy children aged newborn to 11 years, RIs were determined from peripheral sites (presumed to be arcuate...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiology.184.2.1620850
更新日期:1992-08-01 00:00:00